Security record · archived quarter
GPCR
Structure Therapeutics Inc. · Healthcare · Biotechnology
68Tracked holders
-4Δ holders
35.35MShares held
$1.72BReported value
+6New positions
−10Exits
Momentum inputs (comparable managers):
holder breadth -5.6% ·
share flow +3.1% ·
net new positions -5.9%
· formula
Concentrated accumulation: rising shares among fewer holders
All ownership figures: tracked 13F managers only, common-stock positions, reporting period Q1 2026
Ownership over time
| Quarter | Holders | Δ | Shares | Reported value | New | Exits |
|---|---|---|---|---|---|---|
| Q2 2026 | 66 | 0 | 29.19M | $1.56B | +7 | −7 |
| Q1 2026 | 68 | -4 | 35.35M | $1.72B | +6 | −10 |
| Q4 2025 | 71 | 0 | 34.16M | $2.38B | +1 | −1 |
| Q3 2025 | 15 | 0 | 15.29M | $428.25M | +1 | −1 |
| Q2 2025 | 12 | 0 | 15.65M | $324.65M | n/a | n/a |
| Q1 2025 | 10 | +2 | 10.69M | $185.13M | +2 | n/a |
| Q4 2024 | 8 | -1 | 12.53M | $339.72M | n/a | −1 |
| Q3 2024 | 8 | -3 | 13.88M | $609.35M | n/a | −3 |
| Q2 2024 | 11 | n/a | 14.51M | $569.72M | n/a | n/a |
Who holds it · Q1 2026
| # | Manager | Shares | Δ shares | Value | Their weight | Held | ||
|---|---|---|---|---|---|---|---|---|
| 1 | Fidelity (FMR) ✦ | 8.40M | -3.5% | $405.05M | 0.0% | ▼ Trim | 4 | SEC ↗ ×6 |
| 2 | Wellington Management ✦ | 7.26M | +1.9% | $349.95M | 0.1% | ▲ Add | 8 | SEC ↗ ×8 |
| 3 | Janus Henderson Group Plc | 5.35M | +5.2% | $258.26M | 0.1% | ▲ Add | 2 | SEC ↗ ×4 |
| 4 | Morgan Stanley ✦ | 2.31M | +10.4% | $111.12M | 0.0% | ▲ Add | 3 | SEC ↗ ×8 |
| 5 | T. Rowe Price ✦ | 2.00M | +19.7% | $96.43M | 0.0% | ▲ Add | 8 | SEC ↗ |
| 6 | Principal Financial Group Inc | 1.75M | +36.6% | $84.53M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 7 | American Century Companies Inc | 1.44M | +183.7% | $69.31M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 8 | Alliancebernstein L.P. | 638.81K | -24.7% | $44.43M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 9 | Franklin Resources Inc | 531.60K | -38.9% | $25.62M | 0.0% | ▼ Trim | 2 | SEC ↗ ×4 |
| 10 | Healthcare Of Ontario Pension Plan… | 467.80K | 0.0% | $22.55M | 0.0% | Held | 2 | SEC ↗ |
| 11 | BlackRock ✦ (passive) | 441.98K | +2.8% | $21.30M | 0.0% | ▲ Add | 4 | SEC ↗ ×4 |
| 12 | Aberdeen Group plc | 391.81K | +47.9% | $18.89M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 13 | Deutsche Bank Ag\ | 331.87K | -60.5% | $16.00M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 14 | National Bank Of Canada /Fi/ | 305.40K | +15.1% | $14.72M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 15 | Balyasny Asset Management L.P. | 304.93K | +41.0% | $14.70M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 16 | Goldman Sachs Group ✦ | 260.54K | +16.1% | $12.56M | 0.0% | ▲ Add | 3 | SEC ↗ ×2 |
| 17 | Bank Of America Corp /De/ | 227.13K | +617.0% | $10.95M | 0.0% | ▲ Add | 2 | SEC ↗ ×4 |
| 18 | Ameriprise Financial Inc | 219.52K | -23.1% | $10.58M | 0.0% | ▼ Trim | 2 | SEC ↗ ×4 |
| 19 | UBS Group AG | 212.92K | +5.2% | $10.26M | 0.0% | ▲ Add | 2 | SEC ↗ ×2 |
| 20 | D. E. Shaw & Co. ✦ | 204.79K | +2274.9% | $9.87M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 21 | Td Asset Management Inc | 204.76K | +17.2% | $9.87M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 22 | JPMorgan Chase ✦ | 212.80K | +1542.5% | $9.35M | 0.0% | ▲ Add | 3 | SEC ↗ ×6 |
| 23 | Two Sigma Investments ✦ | 181.41K | +89.9% | $8.74M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 24 | Millennium Management ✦ | 168.93K | +10.7% | $8.14M | 0.0% | ▲ Add | 8 | SEC ↗ |
| 25 | Holocene Advisors, LP | 159.01K | New | $7.66M | 0.0% | New | 1 | SEC ↗ |
| 26 | Nomura Asset Management… | 134.01K | +62.2% | $6.46M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 27 | Manufacturers Life Insurance… | 114.81K | +19.1% | $5.53M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 28 | Universal- Beteiligungs- und… | 109.64K | +32.0% | $5.28M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 29 | Schroder Investment Management Group | 118.22K | n/a | $5.19M | 0.0% | n/c | 1 | SEC ↗ |
| 30 | Tudor Investment Corp Et Al | 75.30K | +114.8% | $3.63M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 31 | Qube Research & Technologies Ltd | 73.60K | New | $3.55M | 0.0% | New | 1 | SEC ↗ |
| 32 | Marshall Wace ✦ | 69.11K | -59.0% | $3.33M | 0.0% | ▼ Trim | 2 | SEC ↗ ×2 |
| 33 | Geode Capital Management ✦ (passive) | 67.86K | +23.1% | $3.27M | 0.0% | ▲ Add | 8 | SEC ↗ |
| 34 | Susquehanna International Group, Llp | 55.84K | +520.5% | $2.69M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 35 | Renaissance Technologies ✦ | 55.80K | -51.6% | $2.69M | 0.0% | ▼ Trim | 5 | SEC ↗ |
| 36 | State Street Global Advisors ✦ (passive) | 47.58K | -1.3% | $2.29M | 0.0% | ▼ Trim | 6 | SEC ↗ |
| 37 | Raymond James Financial Inc | 45.14K | +1.7% | $2.18M | 0.0% | ▲ Add | 2 | SEC ↗ ×3 |
| 38 | Osaic Holdings, Inc. | 44.42K | -25.0% | $2.14M | 0.0% | ▼ Trim | 2 | SEC ↗ ×2 |
| 39 | Voya Investment Management Llc | 44.41K | -19.7% | $2.14M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 40 | Bank Of Montreal /Can/ | 39.98K | -26.4% | $1.93M | 0.0% | ▼ Trim | 2 | SEC ↗ ×3 |
| 41 | Mariner, LLC | 34.48K | -21.9% | $1.66M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 42 | Nomura Asset Management Co Ltd | 32.79K | +12.5% | $1.58M | 0.0% | ▲ Add | 2 | SEC ↗ ×2 |
| 43 | Squarepoint Ops LLC | 22.65K | New | $1.09M | 0.0% | New | 1 | SEC ↗ |
| 44 | Citigroup Inc | 20.49K | +179.4% | $987,811 | 0.0% | ▲ Add | 2 | SEC ↗ ×2 |
| 45 | Barclays Plc | 19.19K | +145.0% | $924,861 | 0.0% | ▲ Add | 2 | SEC ↗ ×2 |
| 46 | Sei Investments Co | 13.99K | -6.1% | $674,317 | 0.0% | ▼ Trim | 2 | SEC ↗ ×2 |
| 47 | Mml Investors Services, Llc | 13.89K | +77.5% | $669,353 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 48 | Envestnet Asset Management Inc | 11.38K | -1.7% | $548,371 | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 49 | Stifel Financial Corp | 11.34K | +134.8% | $546,684 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 50 | Bnp Paribas Financial Markets | 10.88K | +24.4% | $524,368 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 51 | Russell Investments Group, Ltd. | 10.70K | -59.3% | $515,797 | 0.0% | ▼ Trim | 2 | SEC ↗ ×5 |
| 52 | HighTower Advisors, LLC | 9.62K | +3.2% | $463,684 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 53 | LPL Financial LLC | 9.26K | +14.2% | $446,332 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 54 | Allianz Asset Management GmbH | 8.60K | -28.3% | $414,520 | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 55 | Wells Fargo & Company/Mn | 7.82K | +38.0% | $376,804 | 0.0% | ▲ Add | 2 | SEC ↗ ×2 |
| 56 | Cetera Investment Advisers | 7.72K | +17.0% | $372,104 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 57 | Mirae Asset Global Investments Co.… | 6.41K | +21.7% | $309,010 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 58 | Peak6 Llc | 6.05K | -61.9% | $291,851 | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 59 | Tidal Investments LLC | 4.64K | New | $223,793 | 0.0% | New | 1 | SEC ↗ |
| 60 | Invesco Ltd. | 4.58K | +43.2% | $220,804 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 61 | Pnc Financial Services Group, Inc. | 2.85K | -27.3% | $137,563 | 0.0% | ▼ Trim | 2 | SEC ↗ ×3 |
| 62 | Assetmark, Inc | 2.54K | +21.4% | $122,621 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 63 | Rockefeller Capital Management L.P. | 2.22K | +203.7% | $107,004 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 64 | Royal Bank Of Canada | 722 | -92.9% | $35,000 | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 65 | Jones Financial Companies Lllp | 341 | -67.4% | $15,659 | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 66 | Zurcher Kantonalbank (Zurich… | 212 | New | $10,218 | 0.0% | New | 1 | SEC ↗ |
| 67 | Cwm, Llc | 125 | -74.0% | $6,025 | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 68 | Us Bancorp \De\ | 10 | New | $482 | 0.0% | New | 1 | SEC ↗ |
“Their weight” = the position's share of that manager's reported 13F equity value: the conviction measure. ✦ = curated manager.
New buyers
| Holocene Advisors, LP | $7.66M | 0.0% |
| Qube Research & Technologies… | $3.55M | 0.0% |
| Squarepoint Ops LLC | $1.09M | 0.0% |
| Tidal Investments LLC | $223,793 | 0.0% |
| Zurcher Kantonalbank (Zurich… | $10,218 | 0.0% |
| Us Bancorp \De\ | $482 | 0.0% |
Exited
| Citadel Advisors | $53.73M | was 0.0% |
| Jane Street Group, Llc | $10.24M | was 0.0% |
| Alyeska Investment Group, L.P. | $8.00M | was 0.0% |
| Simplex Trading, Llc | $6.45M | was 0.2% |
| Northern Trust Corp | $253,509 | was 0.0% |
| Bank of New York Mellon Corp | $250,635 | was 0.0% |
| Cibc World Market Inc. | $225,898 | was 0.0% |
| ProShare Advisors LLC | $205,659 | was 0.0% |
| Daiwa Securities Group Inc. | $13,000 | was 0.0% |
| Northwestern Mutual Wealth… | $4,173 | was 0.0% |
Full-market context: across ALL 13F filers (SEC structured data, Q1 2026): 1 holders, 118.22K shares, $5.19M reported. This is a different, older period than the tracked-universe figures above and the two are never mixed.
Frequently co-owned
What else this security's tracked holders most often hold: shared-ownership counts, not fundamental relationships.
Aug 06
SC 13G/A: FMR LLC
Provenance: Ownership from parsed 13F common-stock positions (tracked universe, comparable sets for changes); insider rows from Forms 3/4/5; stakes from Schedules 13D/13G; every filing links to its original on SEC EDGAR.
Reporting period: Q1 2026 ·
Methodology ·
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