GPCR
Structure Therapeutics Inc. · Healthcare · Biotechnology
Momentum inputs (comparable managers): holder breadth 0.0% · share flow -2.7% · net new positions 0.0% — formula
All ownership figures: tracked 13F managers only, common-stock positions, reporting period Q2 2026
| Quarter | Holders | Δ | Shares | Reported value | New | Exits |
|---|---|---|---|---|---|---|
| Q2 2026 | 66 | 0 | 29.19M | $1.56B | +7 | −7 |
| Q1 2026 | 68 | -4 | 35.35M | $1.72B | +6 | −10 |
| Q4 2025 | 71 | 0 | 34.16M | $2.38B | +1 | −1 |
| Q3 2025 | 15 | 0 | 15.29M | $428.25M | +1 | −1 |
| Q2 2025 | 12 | 0 | 15.65M | $324.65M | — | — |
| Q1 2025 | 10 | +2 | 10.69M | $185.13M | +2 | — |
| Q4 2024 | 8 | -1 | 12.53M | $339.72M | — | −1 |
| Q3 2024 | 8 | -3 | 13.88M | $609.35M | — | −3 |
| Q2 2024 | 11 | — | 14.51M | $569.72M | — | — |
| # | Manager | Shares | Δ shares | Value | Their weight | Held | ||
|---|---|---|---|---|---|---|---|---|
| 1 | Fidelity (FMR) ✦ | 7.81M | -7.1% | $419.18M | 0.0% | ▼ Trim | 5 | SEC ↗ |
| 2 | Fidelity (FMR) ✦ | 7.81M | -7.1% | $419.18M | 0.0% | ▼ Trim | 5 | SEC ↗ |
| 3 | Fidelity (FMR) ✦ | 7.81M | -7.1% | $419.18M | 0.0% | ▼ Trim | 5 | SEC ↗ |
| 4 | Fidelity (FMR) ✦ | 7.81M | -7.1% | $419.18M | 0.0% | ▼ Trim | 5 | SEC ↗ |
| 5 | Fidelity (FMR) ✦ | 7.81M | -7.1% | $419.18M | 0.0% | ▼ Trim | 5 | SEC ↗ |
| 6 | Fidelity (FMR) ✦ | 7.81M | -7.1% | $419.18M | 0.0% | ▼ Trim | 5 | SEC ↗ |
| 7 | Wellington Management ✦ | 7.38M | +1.6% | $396.05M | 0.1% | ▲ Add | 9 | SEC ↗ |
| 8 | Wellington Management ✦ | 7.38M | +1.6% | $396.05M | 0.1% | ▲ Add | 9 | SEC ↗ |
| 9 | Wellington Management ✦ | 7.38M | +1.6% | $396.05M | 0.1% | ▲ Add | 9 | SEC ↗ |
| 10 | Wellington Management ✦ | 7.38M | +1.6% | $396.05M | 0.1% | ▲ Add | 9 | SEC ↗ |
| 11 | Wellington Management ✦ | 7.38M | +1.6% | $396.05M | 0.1% | ▲ Add | 9 | SEC ↗ |
| 12 | Wellington Management ✦ | 7.38M | +1.6% | $396.05M | 0.1% | ▲ Add | 9 | SEC ↗ |
| 13 | Wellington Management ✦ | 7.38M | +1.6% | $396.05M | 0.1% | ▲ Add | 9 | SEC ↗ |
| 14 | Wellington Management ✦ | 7.38M | +1.6% | $396.05M | 0.1% | ▲ Add | 9 | SEC ↗ |
| 15 | Morgan Stanley ✦ | 2.81M | +21.7% | $150.63M | 0.0% | ▲ Add | 4 | SEC ↗ |
| 16 | Morgan Stanley ✦ | 2.81M | +21.7% | $150.63M | 0.0% | ▲ Add | 4 | SEC ↗ |
| 17 | Morgan Stanley ✦ | 2.81M | +21.7% | $150.63M | 0.0% | ▲ Add | 4 | SEC ↗ |
| 18 | Morgan Stanley ✦ | 2.81M | +21.7% | $150.63M | 0.0% | ▲ Add | 4 | SEC ↗ |
| 19 | Morgan Stanley ✦ | 2.81M | +21.7% | $150.63M | 0.0% | ▲ Add | 4 | SEC ↗ |
| 20 | Morgan Stanley ✦ | 2.81M | +21.7% | $150.63M | 0.0% | ▲ Add | 4 | SEC ↗ |
| 21 | Morgan Stanley ✦ | 2.81M | +21.7% | $150.63M | 0.0% | ▲ Add | 4 | SEC ↗ |
| 22 | Morgan Stanley ✦ | 2.81M | +21.7% | $150.63M | 0.0% | ▲ Add | 4 | SEC ↗ |
| 23 | Morgan Stanley ✦ | 2.81M | +21.7% | $150.63M | 0.0% | ▲ Add | 4 | SEC ↗ |
| 24 | Principal Financial Group Inc | 1.75M | -0.1% | $94.07M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 25 | American Century Companies Inc | 1.68M | +17.0% | $90.28M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 26 | T. Rowe Price ✦ | 845.53K | -57.7% | $45.38M | 0.0% | ▼ Trim | 9 | SEC ↗ |
| 27 | Aberdeen Group plc | 639.91K | +63.3% | $34.34M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 28 | Franklin Resources Inc | 578.84K | +8.9% | $31.07M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 29 | Franklin Resources Inc | 578.84K | +8.9% | $31.07M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 30 | Franklin Resources Inc | 578.84K | +8.9% | $31.07M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 31 | Bank Of America Corp /De/ | 563.42K | +148.1% | $30.24M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 32 | Bank Of America Corp /De/ | 563.42K | +148.1% | $30.24M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 33 | Bank Of America Corp /De/ | 563.42K | +148.1% | $30.24M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 34 | Bank Of America Corp /De/ | 563.42K | +148.1% | $30.24M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 35 | Alliancebernstein L.P. | 611.71K | -4.2% | $29.48M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 36 | BlackRock ✦ (passive) | 511.15K | +15.7% | $27.43M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 37 | BlackRock ✦ (passive) | 511.15K | +15.7% | $27.43M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 38 | BlackRock ✦ (passive) | 511.15K | +15.7% | $27.43M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 39 | BlackRock ✦ (passive) | 511.15K | +15.7% | $27.43M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 40 | BlackRock ✦ (passive) | 511.15K | +15.7% | $27.43M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 41 | BlackRock ✦ (passive) | 511.15K | +15.7% | $27.43M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 42 | BlackRock ✦ (passive) | 511.15K | +15.7% | $27.43M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 43 | BlackRock ✦ (passive) | 511.15K | +15.7% | $27.43M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 44 | Healthcare Of Ontario Pension Plan… | 418.80K | -10.5% | $22.48M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 45 | UBS Group AG | 378.99K | +78.0% | $20.34M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 46 | UBS Group AG | 378.99K | +78.0% | $20.34M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 47 | Deutsche Bank Ag\ | 331.87K | 0.0% | $17.81M | 0.0% | Held | 3 | SEC ↗ |
| 48 | Marshall Wace ✦ | 267.59K | +287.2% | $14.36M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 49 | Goldman Sachs Group ✦ | 242.79K | -6.8% | $13.03M | 0.0% | ▼ Trim | 4 | SEC ↗ |
| 50 | Goldman Sachs Group ✦ | 242.79K | -6.8% | $13.03M | 0.0% | ▼ Trim | 4 | SEC ↗ |
| 51 | Ameriprise Financial Inc | 230.51K | +5.0% | $12.37M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 52 | Ameriprise Financial Inc | 230.51K | +5.0% | $12.37M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 53 | Ameriprise Financial Inc | 230.51K | +5.0% | $12.37M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 54 | Ameriprise Financial Inc | 230.51K | +5.0% | $12.37M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 55 | National Bank Of Canada /Fi/ | 215.80K | -29.3% | $11.58M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 56 | Two Sigma Investments ✦ | 204.16K | +12.5% | $10.96M | 0.0% | ▲ Add | 4 | SEC ↗ |
| 57 | Nomura Asset Management… | 153.12K | +14.3% | $8.22M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 58 | Universal- Beteiligungs- und… | 125.69K | +14.6% | $6.75M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 59 | Squarepoint Ops LLC | 125.58K | +454.5% | $6.74M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 60 | Susquehanna International Group, Llp | 122.34K | +119.1% | $6.57M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 61 | D. E. Shaw & Co. ✦ | 115.30K | -43.7% | $6.19M | 0.0% | ▼ Trim | 6 | SEC ↗ |
| 62 | Geode Capital Management ✦ (passive) | 97.18K | +43.2% | $5.22M | 0.0% | ▲ Add | 9 | SEC ↗ |
| 63 | Qube Research & Technologies Ltd | 93.40K | +26.9% | $5.01M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 64 | Millennium Management ✦ | 89.57K | -47.0% | $4.81M | 0.0% | ▼ Trim | 9 | SEC ↗ |
| 65 | Adage Capital Partners ✦ | 75.00K | New | $4.03M | 0.0% | New | 1 | SEC ↗ |
| 66 | Td Asset Management Inc | 68.96K | -66.3% | $3.70M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 67 | Raymond James Financial Inc | 59.36K | +31.5% | $3.19M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 68 | Raymond James Financial Inc | 59.36K | +31.5% | $3.19M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 69 | Raymond James Financial Inc | 59.36K | +31.5% | $3.19M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 70 | Tudor Investment Corp Et Al | 53.66K | -28.7% | $2.88M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 71 | Mariner, LLC | 46.28K | +34.2% | $2.48M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 72 | Osaic Holdings, Inc. | 44.79K | +0.8% | $2.40M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 73 | Osaic Holdings, Inc. | 44.79K | +0.8% | $2.40M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 74 | State Street Global Advisors ✦ (passive) | 44.63K | -6.2% | $2.40M | 0.0% | ▼ Trim | 7 | SEC ↗ |
| 75 | Voya Investment Management Llc | 44.41K | 0.0% | $2.38M | 0.0% | Held | 3 | SEC ↗ |
| 76 | Bank Of Montreal /Can/ | 42.57K | +6.5% | $2.28M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 77 | Bank Of Montreal /Can/ | 42.57K | +6.5% | $2.28M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 78 | Bank Of Montreal /Can/ | 42.57K | +6.5% | $2.28M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 79 | Manufacturers Life Insurance… | 38.11K | -66.8% | $2.05M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 80 | Nomura Asset Management Co Ltd | 32.79K | 0.0% | $1.76M | 0.0% | Held | 3 | SEC ↗ |
| 81 | Nomura Asset Management Co Ltd | 32.79K | 0.0% | $1.76M | 0.0% | Held | 3 | SEC ↗ |
| 82 | Mml Investors Services, Llc | 25.60K | +84.3% | $1.37M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 83 | Nomura Holdings Inc | 22.87K | New | $1.23M | 0.0% | New | 1 | SEC ↗ |
| 84 | Barclays Plc | 20.23K | +5.4% | $1.09M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 85 | Barclays Plc | 20.23K | +5.4% | $1.09M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 86 | Bnp Paribas Financial Markets | 17.78K | +63.4% | $954,306 | 0.0% | ▲ Add | 3 | SEC ↗ |
| 87 | Stifel Financial Corp | 15.03K | +32.5% | $806,771 | 0.0% | ▲ Add | 3 | SEC ↗ |
| 88 | LPL Financial LLC | 14.33K | +54.8% | $769,252 | 0.0% | ▲ Add | 3 | SEC ↗ |
| 89 | Sei Investments Co | 13.68K | -2.2% | $734,422 | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 90 | Sei Investments Co | 13.68K | -2.2% | $734,422 | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 91 | Envestnet Asset Management Inc | 11.57K | +1.7% | $621,241 | 0.0% | ▲ Add | 3 | SEC ↗ |
| 92 | Wells Fargo & Company/Mn | 10.40K | +33.0% | $558,033 | 0.0% | ▲ Add | 3 | SEC ↗ |
| 93 | Wells Fargo & Company/Mn | 10.40K | +33.0% | $558,033 | 0.0% | ▲ Add | 3 | SEC ↗ |
| 94 | HighTower Advisors, LLC | 10.03K | +4.2% | $538,253 | 0.0% | ▲ Add | 3 | SEC ↗ |
| 95 | Citigroup Inc | 9.68K | -52.8% | $519,526 | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 96 | Citigroup Inc | 9.68K | -52.8% | $519,526 | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 97 | IMC-Chicago, LLC | 8.62K | New | $462,528 | 0.0% | New | 1 | SEC ↗ |
| 98 | Simplex Trading, Llc | 7.87K | New | $422,436 | 0.0% | New | 1 | SEC ↗ |
| 99 | Allianz Asset Management GmbH | 8.60K | 0.0% | $414,520 | 0.0% | Held | 3 | SEC ↗ |
| 100 | Cetera Investment Advisers | 6.64K | -14.0% | $356,261 | 0.0% | ▼ Trim | 3 | SEC ↗ |
“Their weight” = the position's share of that manager's reported 13F equity value — the conviction measure. ✦ = curated manager.
New buyers
| Adage Capital Partners | $4.03M | 0.0% |
| Nomura Holdings Inc | $1.23M | 0.0% |
| IMC-Chicago, LLC | $462,528 | 0.0% |
| Simplex Trading, Llc | $422,436 | 0.0% |
Exited
| Balyasny Asset Management L.P. | $14.70M | was 0.0% |
| Holocene Advisors, LP | $7.66M | was 0.0% |
| Schroder Investment… | $5.19M | was 0.0% |
| Renaissance Technologies | $2.69M | was 0.0% |
| Russell Investments Group… | $515,797 | was 0.0% |
| Tidal Investments LLC | $223,793 | was 0.0% |
| Us Bancorp \De\ | $482 | was 0.0% |
Full-market context: across ALL 13F filers (SEC structured data, Q1 2026): 1 holders, 118.22K shares, $5.19M reported. This is a different, older period than the tracked-universe figures above and the two are never mixed.
What else this security's tracked holders most often hold — shared-ownership counts, not fundamental relationships.