GPCR
Structure Therapeutics Inc. · Healthcare · Biotechnology
Momentum inputs (comparable managers):
holder breadth -11.1% ·
share flow -9.8% ·
net new positions -12.5%
— formula
Broad distribution — falling shares and fewer holders
All ownership figures: tracked 13F managers only, common-stock positions, reporting period Q4 2024
| Quarter | Holders | Δ | Shares | Reported value | New | Exits |
|---|---|---|---|---|---|---|
| Q2 2026 | 66 | 0 | 29.19M | $1.56B | +7 | −7 |
| Q1 2026 | 68 | -4 | 35.35M | $1.72B | +6 | −10 |
| Q4 2025 | 71 | 0 | 34.16M | $2.38B | +1 | −1 |
| Q3 2025 | 15 | 0 | 15.29M | $428.25M | +1 | −1 |
| Q2 2025 | 12 | 0 | 15.65M | $324.65M | — | — |
| Q1 2025 | 10 | +2 | 10.69M | $185.13M | +2 | — |
| Q4 2024 | 8 | -1 | 12.53M | $339.72M | — | −1 |
| Q3 2024 | 8 | -3 | 13.88M | $609.35M | — | −3 |
| Q2 2024 | 11 | — | 14.51M | $569.72M | — | — |
| # | Manager | Shares | Δ shares | Value | Their weight | Held | ||
|---|---|---|---|---|---|---|---|---|
| 1 | Wellington Management ✦ | 7.79M | +0.2% | $211.15M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 2 | Wellington Management ✦ | 7.79M | +0.2% | $211.15M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 3 | Wellington Management ✦ | 7.79M | +0.2% | $211.15M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 4 | Wellington Management ✦ | 7.79M | +0.2% | $211.15M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 5 | Wellington Management ✦ | 7.79M | +0.2% | $211.15M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 6 | Wellington Management ✦ | 7.79M | +0.2% | $211.15M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 7 | Citadel Advisors ✦ | 1.48M | +1.9% | $40.12M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 8 | Citadel Advisors ✦ | 1.48M | +1.9% | $40.12M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 9 | T. Rowe Price ✦ | 1.39M | -33.1% | $37.81M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 10 | Millennium Management ✦ | 751.01K | -17.6% | $20.37M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 11 | Marshall Wace ✦ | 583.21K | +339.6% | $15.82M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 12 | Marshall Wace ✦ | 583.21K | +339.6% | $15.82M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 13 | Marshall Wace ✦ | 583.21K | +339.6% | $15.82M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 14 | Point72 Asset Management ✦ | 476.70K | -61.5% | $12.93M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 15 | Geode Capital Management ✦ (passive) | 45.70K | +1.1% | $1.24M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 16 | State Street Global Advisors ✦ (passive) | 10.53K | — | $285,492 | 0.0% | n/c | 1 | SEC ↗ |
“Their weight” = the position's share of that manager's reported 13F equity value — the conviction measure. ✦ = curated manager.
New buyers
| No new tracked buyers this quarter. |
Exited
| Adage Capital Partners | $10.97M | was 0.0% |
Full-market context: across ALL 13F filers (SEC structured data, Q1 2026): 1 holders, 118.22K shares, $5.19M reported. This is a different, older period than the tracked-universe figures above and the two are never mixed.
What else this security's tracked holders most often hold — shared-ownership counts, not fundamental relationships.