证券记录
SYRE
Spyre Therapeutics, Inc. · Healthcare · Biotechnology
99被追踪持有人
+22Δ持有人
55.43M持有股份
$4.93B报告持仓市值
+25新建仓位
−3清仓
动量输入（同类管理人）：
持有人广度 +28.6% ·
股份流向 +30.0% ·
净新建仓位 +20.0%
— 公式
广泛积累 — 持股数量上升且持有人增多
所有持股数据：仅限已追踪的 13F 管理人，普通股持仓，报告期 Q2 2026
持股变化趋势
| 季度 | 持有人 | Δ | 股份 | 报告持仓市值 | 新增 | 清仓 |
|---|---|---|---|---|---|---|
| Q2 2026 | 99 | +22 | 55.43M | $4.93B | +25 | −3 |
| Q1 2026 | 80 | +10 | 41.69M | $2.10B | +12 | −2 |
| Q4 2025 | 69 | +2 | 41.90M | $1.37B | +2 | — |
| Q3 2025 | 13 | -1 | 23.21M | $388.94M | +1 | −2 |
| Q2 2025 | 11 | 0 | 22.40M | $335.38M | +2 | −2 |
| Q1 2025 | 8 | -2 | 6.01M | $96.96M | — | −2 |
| Q4 2024 | 10 | +1 | 7.67M | $178.64M | +2 | −1 |
| Q3 2024 | 8 | 0 | 4.78M | $140.58M | +1 | −1 |
| Q2 2024 | 8 | — | 3.96M | $93.00M | — | — |
持有人 · Q2 2026
| # | 管理人 | 股份 | Δ股份 | 价值 | 其权重 | 持有 | ||
|---|---|---|---|---|---|---|---|---|
| 1 | Fidelity (FMR) ✦ | 13.03M | +10.6% | $1.16B | 0.1% | ▲ Add | 5 | SEC ↗ |
| 2 | Fidelity (FMR) ✦ | 13.03M | +10.6% | $1.16B | 0.1% | ▲ Add | 5 | SEC ↗ |
| 3 | Fidelity (FMR) ✦ | 13.03M | +10.6% | $1.16B | 0.1% | ▲ Add | 5 | SEC ↗ |
| 4 | Fidelity (FMR) ✦ | 13.03M | +10.6% | $1.16B | 0.1% | ▲ Add | 5 | SEC ↗ |
| 5 | BlackRock ✦ (被动) | 6.51M | +17.9% | $577.66M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 6 | BlackRock ✦ (被动) | 6.51M | +17.9% | $577.66M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 7 | BlackRock ✦ (被动) | 6.51M | +17.9% | $577.66M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 8 | BlackRock ✦ (被动) | 6.51M | +17.9% | $577.66M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 9 | BlackRock ✦ (被动) | 6.51M | +17.9% | $577.66M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 10 | BlackRock ✦ (被动) | 6.51M | +17.9% | $577.66M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 11 | BlackRock ✦ (被动) | 6.51M | +17.9% | $577.66M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 12 | BlackRock ✦ (被动) | 6.51M | +17.9% | $577.66M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 13 | BlackRock ✦ (被动) | 6.51M | +17.9% | $577.66M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 14 | BlackRock ✦ (被动) | 6.51M | +17.9% | $577.66M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 15 | BlackRock ✦ (被动) | 6.51M | +17.9% | $577.66M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 16 | BlackRock ✦ (被动) | 6.51M | +17.9% | $577.66M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 17 | BlackRock ✦ (被动) | 6.51M | +17.9% | $577.66M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 18 | BlackRock ✦ (被动) | 6.51M | +17.9% | $577.66M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 19 | BlackRock ✦ (被动) | 6.51M | +17.9% | $577.66M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 20 | Vanguard Capital Management Llc | 3.45M | +12.8% | $306.17M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 21 | State Street Global Advisors ✦ (被动) | 3.06M | +17.3% | $271.44M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 22 | T. Rowe Price ✦ | 2.96M | +85.2% | $262.87M | 0.0% | ▲ Add | 9 | SEC ↗ |
| 23 | T. Rowe Price ✦ | 2.96M | +85.2% | $262.87M | 0.0% | ▲ Add | 9 | SEC ↗ |
| 24 | Geode Capital Management ✦ (被动) | 2.56M | +48.9% | $239.26M | 0.0% | ▲ Add | 9 | SEC ↗ |
| 25 | Geode Capital Management ✦ (被动) | 2.56M | +48.9% | $239.26M | 0.0% | ▲ Add | 9 | SEC ↗ |
| 26 | Capital World Investors ✦ | 2.32M | +247.4% | $205.57M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 27 | Bank Of America Corp /De/ | 1.78M | +44.8% | $157.84M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 28 | Bank Of America Corp /De/ | 1.78M | +44.8% | $157.84M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 29 | Bank Of America Corp /De/ | 1.78M | +44.8% | $157.84M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 30 | Adage Capital Partners ✦ | 1.72M | 新增 | $152.91M | 0.2% | New | 1 | SEC ↗ |
| 31 | Wellington Management ✦ | 1.58M | -13.3% | $140.41M | 0.0% | ▼ Trim | 9 | SEC ↗ |
| 32 | Wellington Management ✦ | 1.58M | -13.3% | $140.41M | 0.0% | ▼ Trim | 9 | SEC ↗ |
| 33 | Wellington Management ✦ | 1.58M | -13.3% | $140.41M | 0.0% | ▼ Trim | 9 | SEC ↗ |
| 34 | Wellington Management ✦ | 1.58M | -13.3% | $140.41M | 0.0% | ▼ Trim | 9 | SEC ↗ |
| 35 | Wellington Management ✦ | 1.58M | -13.3% | $140.41M | 0.0% | ▼ Trim | 9 | SEC ↗ |
| 36 | Wellington Management ✦ | 1.58M | -13.3% | $140.41M | 0.0% | ▼ Trim | 9 | SEC ↗ |
| 37 | Wellington Management ✦ | 1.58M | -13.3% | $140.41M | 0.0% | ▼ Trim | 9 | SEC ↗ |
| 38 | Wellington Management ✦ | 1.58M | -13.3% | $140.41M | 0.0% | ▼ Trim | 9 | SEC ↗ |
| 39 | Wellington Management ✦ | 1.58M | -13.3% | $140.41M | 0.0% | ▼ Trim | 9 | SEC ↗ |
| 40 | Goldman Sachs Group ✦ | 1.48M | +447.6% | $131.22M | 0.0% | ▲ Add | 4 | SEC ↗ |
| 41 | Goldman Sachs Group ✦ | 1.48M | +447.6% | $131.22M | 0.0% | ▲ Add | 4 | SEC ↗ |
| 42 | Goldman Sachs Group ✦ | 1.48M | +447.6% | $131.22M | 0.0% | ▲ Add | 4 | SEC ↗ |
| 43 | Goldman Sachs Group ✦ | 1.48M | +447.6% | $131.22M | 0.0% | ▲ Add | 4 | SEC ↗ |
| 44 | Goldman Sachs Group ✦ | 1.48M | +447.6% | $131.22M | 0.0% | ▲ Add | 4 | SEC ↗ |
| 45 | Goldman Sachs Group ✦ | 1.48M | +447.6% | $131.22M | 0.0% | ▲ Add | 4 | SEC ↗ |
| 46 | Goldman Sachs Group ✦ | 1.48M | +447.6% | $131.22M | 0.0% | ▲ Add | 4 | SEC ↗ |
| 47 | Franklin Resources Inc | 1.47M | +66.8% | $130.77M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 48 | Franklin Resources Inc | 1.47M | +66.8% | $130.77M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 49 | Franklin Resources Inc | 1.47M | +66.8% | $130.77M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 50 | Franklin Resources Inc | 1.47M | +66.8% | $130.77M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 51 | JPMorgan Chase ✦ | 1.09M | +11.6% | $98.87M | 0.0% | ▲ Add | 4 | SEC ↗ |
| 52 | JPMorgan Chase ✦ | 1.09M | +11.6% | $98.87M | 0.0% | ▲ Add | 4 | SEC ↗ |
| 53 | JPMorgan Chase ✦ | 1.09M | +11.6% | $98.87M | 0.0% | ▲ Add | 4 | SEC ↗ |
| 54 | JPMorgan Chase ✦ | 1.09M | +11.6% | $98.87M | 0.0% | ▲ Add | 4 | SEC ↗ |
| 55 | JPMorgan Chase ✦ | 1.09M | +11.6% | $98.87M | 0.0% | ▲ Add | 4 | SEC ↗ |
| 56 | JPMorgan Chase ✦ | 1.09M | +11.6% | $98.87M | 0.0% | ▲ Add | 4 | SEC ↗ |
| 57 | JPMorgan Chase ✦ | 1.09M | +11.6% | $98.87M | 0.0% | ▲ Add | 4 | SEC ↗ |
| 58 | Holocene Advisors, LP | 1.02M | 新增 | $90.13M | 0.2% | New | 1 | SEC ↗ |
| 59 | Marshall Wace ✦ | 991.69K | +612.1% | $88.04M | 0.1% | ▲ Add | 2 | SEC ↗ |
| 60 | Marshall Wace ✦ | 991.69K | +612.1% | $88.04M | 0.1% | ▲ Add | 2 | SEC ↗ |
| 61 | Marshall Wace ✦ | 991.69K | +612.1% | $88.04M | 0.1% | ▲ Add | 2 | SEC ↗ |
| 62 | Capital International Investors | 955.20K | -45.3% | $84.80M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 63 | UBS Group AG | 843.07K | +25.6% | $74.85M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 64 | UBS Group AG | 843.07K | +25.6% | $74.85M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 65 | UBS Group AG | 843.07K | +25.6% | $74.85M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 66 | UBS Group AG | 843.07K | +25.6% | $74.85M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 67 | Northern Trust Corp | 674.53K | +16.5% | $59.88M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 68 | Northern Trust Corp | 674.53K | +16.5% | $59.88M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 69 | Northern Trust Corp | 674.53K | +16.5% | $59.88M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 70 | Northern Trust Corp | 674.53K | +16.5% | $59.88M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 71 | Northern Trust Corp | 674.53K | +16.5% | $59.88M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 72 | Charles Schwab Investment… | 652.96K | +16.1% | $57.97M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 73 | Pictet Asset Management Holding SA | 628.14K | +27.8% | $55.77M | 0.1% | ▲ Add | 3 | SEC ↗ |
| 74 | Victory Capital Management Inc | 553.98K | +89.6% | $49.18M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 75 | UBS AM, a distinct business unit of… | 522.07K | +151.8% | $46.35M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 76 | UBS AM, a distinct business unit of… | 522.07K | +151.8% | $46.35M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 77 | UBS AM, a distinct business unit of… | 522.07K | +151.8% | $46.35M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 78 | UBS AM, a distinct business unit of… | 522.07K | +151.8% | $46.35M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 79 | UBS AM, a distinct business unit of… | 522.07K | +151.8% | $46.35M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 80 | UBS AM, a distinct business unit of… | 522.07K | +151.8% | $46.35M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 81 | UBS AM, a distinct business unit of… | 522.07K | +151.8% | $46.35M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 82 | UBS AM, a distinct business unit of… | 522.07K | +151.8% | $46.35M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 83 | UBS AM, a distinct business unit of… | 522.07K | +151.8% | $46.35M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 84 | Morgan Stanley ✦ | 499.96K | +102.6% | $44.39M | 0.0% | ▲ Add | 4 | SEC ↗ |
| 85 | Morgan Stanley ✦ | 499.96K | +102.6% | $44.39M | 0.0% | ▲ Add | 4 | SEC ↗ |
| 86 | Morgan Stanley ✦ | 499.96K | +102.6% | $44.39M | 0.0% | ▲ Add | 4 | SEC ↗ |
| 87 | Morgan Stanley ✦ | 499.96K | +102.6% | $44.39M | 0.0% | ▲ Add | 4 | SEC ↗ |
| 88 | Morgan Stanley ✦ | 499.96K | +102.6% | $44.39M | 0.0% | ▲ Add | 4 | SEC ↗ |
| 89 | Morgan Stanley ✦ | 499.96K | +102.6% | $44.39M | 0.0% | ▲ Add | 4 | SEC ↗ |
| 90 | Voya Investment Management Llc | 431.69K | +699.9% | $38.33M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 91 | Voya Investment Management Llc | 431.69K | +699.9% | $38.33M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 92 | Voya Investment Management Llc | 431.69K | +699.9% | $38.33M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 93 | Ameriprise Financial Inc | 356.08K | +123.7% | $31.61M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 94 | Ameriprise Financial Inc | 356.08K | +123.7% | $31.61M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 95 | Ameriprise Financial Inc | 356.08K | +123.7% | $31.61M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 96 | Jennison Associates Llc | 303.18K | 新增 | $26.92M | 0.0% | New | 1 | SEC ↗ |
| 97 | Bnp Paribas Financial Markets | 259.92K | +1295.2% | $23.08M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 98 | Bank of New York Mellon Corp | 245.19K | +28.1% | $21.77M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 99 | Bank of New York Mellon Corp | 245.19K | +28.1% | $21.77M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 100 | Bank of New York Mellon Corp | 245.19K | +28.1% | $21.77M | 0.0% | ▲ Add | 3 | SEC ↗ |
"持仓权重"= 该持仓占该管理人已申报13F股权价值的比例——即信念度衡量指标。✦ = 精选管理人。
新增买入方
| Adage Capital Partners | $152.91M | 0.2% |
| Holocene Advisors, LP | $90.13M | 0.2% |
| Jennison Associates Llc | $26.92M | 0.0% |
已清仓
| Assenagon Asset Management… | $940,555 | 曾为 0.0% |
| Capstone Investment Advisors… | $380,166 | 曾为 0.0% |
| Group One Trading Llc | $45,446 | 曾为 0.0% |
全市场背景: 涵盖所有13F申报机构（SEC结构化数据， Q1 2026): 197 持有人, 82.12M 股份, $4.06B 已申报. 这是与上方被追踪全域数据不同的较早期间，两者从不混用。
常见共同持仓
该证券的被追踪持有人最常同时持有的其他证券——基于共同持有计数，而非基本面关联。
公开市场买入 (P)
在我们的覆盖窗口内无内部人士公开市场买入记录。
公开市场卖出 (S)
Aug 07
Albers Jeffrey W.
Director · 5.00K 股 · $522,350
Aug 07
Albers Jeffrey W.
Director · 8.00K 股 · $835,040
Aug 07
Albers Jeffrey W.
Director · 10.00K 股 · $1.05M
授予、行权及税务代扣代缴在本平台均不计入买入或卖出。 方法论
Aug 14
SC 13G/A — RTW INVESTMENTS, LP
Aug 14
SC 13G/A — PERCEPTIVE ADVISORS LLC
Jun 23
SC 13D/A — Fairmount Funds Management LLC
9.2% 占股份类别 · 查看 SEC 原始申报文件 ↗
数据来源: 持股数据来源于已解析的13F普通股持仓（被追踪范围，变动对比集）；内部人行为来自Form 3/4/5；重大持股来自Schedule 13D/13G；所有文件均链接至SEC EDGAR原始申报。
报告期: Q2 2026 ·
方法论 ·
通过API获取此数据