SYRE
Spyre Therapeutics, Inc. · Healthcare · Biotechnology
Señales de momentum (gestores comparables):
amplitud de titulares +3.0% ·
flujo de acciones +18.7% ·
nuevas posiciones netas +2.9%
— fórmula
Acumulación amplia — aumento de acciones entre más titulares
Todas las cifras de propiedad: únicamente gestores 13F seguidos, posiciones en acciones ordinarias, período de referencia Q4 2025
| Trimestre | Titulares | Δ | Acciones | Valor declarado | Nuevo | Cierres |
|---|---|---|---|---|---|---|
| Q2 2026 | 99 | +22 | 55.44M | $4.93B | +25 | −3 |
| Q1 2026 | 80 | +10 | 41.69M | $2.10B | +12 | −2 |
| Q4 2025 | 69 | +2 | 41.90M | $1.37B | +2 | — |
| Q3 2025 | 13 | -1 | 23.21M | $388.94M | +1 | −2 |
| Q2 2025 | 11 | 0 | 22.40M | $335.38M | +2 | −2 |
| Q1 2025 | 8 | -2 | 6.01M | $96.96M | — | −2 |
| Q4 2024 | 10 | +1 | 7.67M | $178.64M | +2 | −1 |
| Q3 2024 | 8 | 0 | 4.78M | $140.58M | +1 | −1 |
| Q2 2024 | 8 | — | 3.96M | $93.00M | — | — |
| # | Gestor | Acciones | Δ acciones | Valor | Su ponderación | Mantenida | ||
|---|---|---|---|---|---|---|---|---|
| 1 | Fidelity (FMR) ✦ | 11.64M | +28.5% | $381.29M | 0.0% | ▲ Add | 3 | SEC ↗ ×3 |
| 2 | BlackRock ✦ (pasivo) | 5.52M | +38.6% | $180.90M | 0.0% | ▲ Add | 3 | SEC ↗ ×12 |
| 3 | The Vanguard Group ✦ (pasivo) | 4.04M | +32.3% | $132.19M | 0.0% | ▲ Add | 3 | SEC ↗ ×5 |
| 4 | Capital International Investors | 3.49M | — | $114.42M | 0.0% | n/c | 1 | SEC ↗ |
| 5 | State Street Global Advisors ✦ (pasivo) | 2.26M | +26.8% | $74.13M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 6 | Janus Henderson Group Plc | 1.83M | — | $59.92M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 7 | Geode Capital Management ✦ (pasivo) | 1.66M | +35.4% | $54.36M | 0.0% | ▲ Add | 7 | SEC ↗ ×2 |
| 8 | T. Rowe Price ✦ | 1.60M | +158.1% | $52.48M | 0.0% | ▲ Add | 7 | SEC ↗ ×2 |
| 9 | Wellington Management ✦ | 1.55M | -5.5% | $50.75M | 0.0% | ▼ Trim | 7 | SEC ↗ ×7 |
| 10 | Franklin Resources Inc | 1.11M | — | $36.34M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 11 | Pictet Asset Management Holding SA | 913.96K | — | $29.94M | 0.0% | n/c | 1 | SEC ↗ |
| 12 | UBS Group AG | 680.57K | — | $22.30M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 13 | Point72 Asset Management ✦ | 662.35K | Nuevo | $21.70M | 0.0% | New | 1 | SEC ↗ |
| 14 | Charles Schwab Investment… | 574.62K | — | $18.82M | 0.0% | n/c | 1 | SEC ↗ |
| 15 | Northern Trust Corp | 561.02K | — | $18.38M | 0.0% | n/c | 1 | SEC ↗ ×6 |
| 16 | Bank Of America Corp /De/ | 419.73K | — | $13.75M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 17 | Goldman Sachs Group ✦ | 275.06K | -16.5% | $9.01M | 0.0% | ▼ Trim | 2 | SEC ↗ ×2 |
| 18 | Capital World Investors ✦ | 200.17K | 0.0% | $6.56M | 0.0% | Held | 5 | SEC ↗ |
| 19 | Bank of New York Mellon Corp | 192.83K | — | $6.32M | 0.0% | n/c | 1 | SEC ↗ ×4 |
| 20 | Morgan Stanley ✦ | 182.73K | -45.4% | $5.99M | 0.0% | ▼ Trim | 2 | SEC ↗ ×6 |
| 21 | Barclays Plc | 182.52K | — | $5.98M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 22 | Universal- Beteiligungs- und… | 171.21K | — | $5.61M | 0.0% | n/c | 1 | SEC ↗ |
| 23 | Nuveen, LLC | 150.98K | — | $4.95M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 24 | Invesco Ltd. | 150.93K | — | $4.94M | 0.0% | n/c | 1 | SEC ↗ ×4 |
| 25 | Td Asset Management Inc | 149.82K | — | $4.91M | 0.0% | n/c | 1 | SEC ↗ |
| 26 | Victory Capital Management Inc | 146.08K | — | $4.79M | 0.0% | n/c | 1 | SEC ↗ |
| 27 | Manufacturers Life Insurance… | 129.01K | — | $4.14M | 0.0% | n/c | 1 | SEC ↗ |
| 28 | Deutsche Bank Ag\ | 121.94K | — | $3.99M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 29 | Mercer Global Advisors Inc /Adv | 106.32K | — | $3.48M | 0.0% | n/c | 1 | SEC ↗ |
| 30 | Citigroup Inc | 100.06K | — | $3.28M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 31 | Swiss National Bank | 96.50K | — | $3.16M | 0.0% | n/c | 1 | SEC ↗ |
| 32 | Rhumbline Advisers | 82.96K | — | $2.72M | 0.0% | n/c | 1 | SEC ↗ |
| 33 | Wells Fargo & Company/Mn | 82.42K | — | $2.70M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 34 | Dimensional Fund Advisors Lp | 77.29K | — | $2.53M | 0.0% | n/c | 1 | SEC ↗ |
| 35 | Millennium Management ✦ | 76.19K | -81.3% | $2.50M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 36 | Balyasny Asset Management L.P. | 73.47K | — | $2.41M | 0.0% | n/c | 1 | SEC ↗ |
| 37 | Alliancebernstein L.P. | 67.50K | — | $2.21M | 0.0% | n/c | 1 | SEC ↗ |
| 38 | Citadel Advisors ✦ | 63.90K | Nuevo | $2.09M | 0.0% | New | 1 | SEC ↗ |
| 39 | JPMorgan Chase ✦ | 62.95K | -88.6% | $2.06M | 0.0% | ▼ Trim | 2 | SEC ↗ ×4 |
| 40 | UBS AM, a distinct business unit of… | 62.22K | — | $2.04M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 41 | Legal & General Group Plc | 56.45K | — | $1.85M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 42 | California State Teachers… | 48.04K | — | $1.57M | 0.0% | n/c | 1 | SEC ↗ |
| 43 | Ameriprise Financial Inc | 38.26K | — | $1.25M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 44 | MIRAE ASSET GLOBAL ETFS HOLDINGS… | 35.14K | — | $1.15M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 45 | Voya Investment Management Llc | 27.28K | — | $893,594 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 46 | State Of Wisconsin Investment Board | 27.25K | — | $892,776 | 0.0% | n/c | 1 | SEC ↗ |
| 47 | Assenagon Asset Management S.A. | 22.14K | — | $725,175 | 0.0% | n/c | 1 | SEC ↗ |
| 48 | New York State Common Retirement… | 19.16K | — | $627,845 | 0.0% | n/c | 1 | SEC ↗ |
| 49 | AQR Capital Management ✦ | 17.82K | +4.5% | $583,783 | 0.0% | ▲ Add | 3 | SEC ↗ ×5 |
| 50 | ProShare Advisors LLC | 15.99K | — | $523,801 | 0.0% | n/c | 1 | SEC ↗ |
| 51 | Bnp Paribas Financial Markets | 11.84K | — | $388,009 | 0.0% | n/c | 1 | SEC ↗ |
| 52 | Zurcher Kantonalbank (Zurich… | 11.16K | — | $365,733 | 0.0% | n/c | 1 | SEC ↗ |
| 53 | Tudor Investment Corp Et Al | 10.13K | — | $331,761 | 0.0% | n/c | 1 | SEC ↗ |
| 54 | State Board Of Administration Of… | 9.03K | — | $295,823 | 0.0% | n/c | 1 | SEC ↗ |
| 55 | Sei Investments Co | 6.12K | — | $200,393 | 0.0% | n/c | 1 | SEC ↗ |
| 56 | Susquehanna International Group, Llp | 6.11K | — | $200,196 | 0.0% | n/c | 1 | SEC ↗ |
| 57 | Russell Investments Group, Ltd. | 5.55K | — | $181,948 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 58 | Mirae Asset Global Investments Co.… | 3.77K | — | $123,505 | 0.0% | n/c | 1 | SEC ↗ |
| 59 | Cwm, Llc | 1.97K | — | $65,000 | 0.0% | n/c | 1 | SEC ↗ |
| 60 | Royal Bank Of Canada | 1.99K | — | $65,000 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 61 | BNP Paribas Asset Management… | 656 | — | $21,000 | 0.0% | n/c | 1 | SEC ↗ |
| 62 | Rockefeller Capital Management L.P. | 549 | — | $17,985 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 63 | Group One Trading Llc | 400 | — | $13,104 | 0.0% | n/c | 1 | SEC ↗ |
| 64 | Osaic Holdings, Inc. | 367 | — | $12,022 | 0.0% | n/c | 1 | SEC ↗ |
| 65 | Daiwa Securities Group Inc. | 258 | — | $8,000 | 0.0% | n/c | 1 | SEC ↗ |
| 66 | Optiver Holding B.V. | 240 | — | $7,862 | 0.0% | n/c | 1 | SEC ↗ |
| 67 | Pnc Financial Services Group, Inc. | 86 | — | $2,818 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 68 | Us Bancorp \De\ | 10 | — | $328 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 69 | Nomura Asset Management Co Ltd | 0 | — | $0 | 0.0% | n/c | 1 | SEC ↗ |
«Su ponderación» = la participación de la posición en el valor de renta variable 13F declarado por ese gestor — la medida de convicción. ✦ = gestor seleccionado.
Nuevos compradores
| Point72 Asset Management | $21.70M | 0.0% |
| Citadel Advisors | $2.09M | 0.0% |
Posición cerrada
| Sin salidas rastreadas este trimestre. |
Contexto de mercado completo: entre TODOS los filers 13F (datos estructurados SEC, Q1 2026): 197 tenedores, 82.12M acciones, $4.06B declarado. Este es un período diferente y anterior al de las cifras del universo rastreado que figuran arriba, y ambos nunca se mezclan.
Qué otros valores suelen tener también los tenedores rastreados de este activo — recuentos de cotenencia, no relaciones fundamentales.
Compras en mercado abierto (P)
Sin compras en mercado abierto por parte de insiders en nuestra ventana de cobertura.
Ventas en mercado abierto (S)
Officer · 229 acc. · $21,428
Officer · 1.50K acc. · $135,405
Officer · 3.07K acc. · $285,449
Officer · 600 acc. · $53,442
Officer · 2.10K acc. · $193,032
Officer · 17.50K acc. · $1.57M
Officer · 18.23K acc. · $1.63M
Officer · 400 acc. · $36,000
Officer · 16.55K acc. · $1.44M
Officer · 900 acc. · $77,625
Las adjudicaciones, ejercicios y retenciones fiscales nunca se contabilizan aquí como compras o ventas. Metodología
9.2% de clase · Ver presentación original ante la SEC ↗
9.2% de clase · Ver presentación original ante la SEC ↗