Ficha del valor
SYRE
Spyre Therapeutics, Inc. · Healthcare · Biotechnology
99Tenedores rastreados
+22Δ titulares
55.44MAcciones mantenidas
$4.93BValor declarado
+25Nuevas posiciones
−3Cierres
Señales de momentum (gestores comparables):
amplitud de titulares +28.6% ·
flujo de acciones +30.0% ·
nuevas posiciones netas +20.0%
— fórmula
Acumulación amplia — aumento de acciones entre más titulares
Todas las cifras de propiedad: únicamente gestores 13F seguidos, posiciones en acciones ordinarias, período de referencia Q2 2026
Participación a lo largo del tiempo
| Trimestre | Titulares | Δ | Acciones | Valor declarado | Nuevo | Cierres |
|---|---|---|---|---|---|---|
| Q2 2026 | 99 | +22 | 55.44M | $4.93B | +25 | −3 |
| Q1 2026 | 80 | +10 | 41.69M | $2.10B | +12 | −2 |
| Q4 2025 | 69 | +2 | 41.90M | $1.37B | +2 | — |
| Q3 2025 | 13 | -1 | 23.21M | $388.94M | +1 | −2 |
| Q2 2025 | 11 | 0 | 22.40M | $335.38M | +2 | −2 |
| Q1 2025 | 8 | -2 | 6.01M | $96.96M | — | −2 |
| Q4 2024 | 10 | +1 | 7.67M | $178.64M | +2 | −1 |
| Q3 2024 | 8 | 0 | 4.78M | $140.58M | +1 | −1 |
| Q2 2024 | 8 | — | 3.96M | $93.00M | — | — |
Quién lo tiene en cartera · Q2 2026
| # | Gestor | Acciones | Δ acciones | Valor | Su ponderación | Mantenida | ||
|---|---|---|---|---|---|---|---|---|
| 1 | Fidelity (FMR) ✦ | 13.03M | +10.6% | $1.16B | 0.1% | ▲ Add | 5 | SEC ↗ ×4 |
| 2 | BlackRock ✦ (pasivo) | 6.51M | +17.9% | $577.66M | 0.0% | ▲ Add | 5 | SEC ↗ ×15 |
| 3 | Vanguard Capital Management Llc | 3.45M | +12.8% | $306.17M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 4 | State Street Global Advisors ✦ (pasivo) | 3.06M | +17.3% | $271.44M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 5 | T. Rowe Price ✦ | 2.96M | +85.2% | $262.87M | 0.0% | ▲ Add | 9 | SEC ↗ ×2 |
| 6 | Geode Capital Management ✦ (pasivo) | 2.56M | +48.9% | $239.26M | 0.0% | ▲ Add | 9 | SEC ↗ ×2 |
| 7 | Capital World Investors ✦ | 2.32M | +247.4% | $205.57M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 8 | Bank Of America Corp /De/ | 1.78M | +44.8% | $157.84M | 0.0% | ▲ Add | 3 | SEC ↗ ×3 |
| 9 | Adage Capital Partners ✦ | 1.72M | Nuevo | $152.91M | 0.2% | New | 1 | SEC ↗ |
| 10 | Wellington Management ✦ | 1.58M | -13.3% | $140.41M | 0.0% | ▼ Trim | 9 | SEC ↗ ×9 |
| 11 | Goldman Sachs Group ✦ | 1.48M | +447.6% | $131.22M | 0.0% | ▲ Add | 4 | SEC ↗ ×7 |
| 12 | Franklin Resources Inc | 1.47M | +66.8% | $130.77M | 0.0% | ▲ Add | 3 | SEC ↗ ×4 |
| 13 | JPMorgan Chase ✦ | 1.09M | +11.6% | $98.87M | 0.0% | ▲ Add | 4 | SEC ↗ ×7 |
| 14 | Holocene Advisors, LP | 1.02M | Nuevo | $90.13M | 0.2% | New | 1 | SEC ↗ |
| 15 | Marshall Wace ✦ | 991.69K | +612.1% | $88.04M | 0.1% | ▲ Add | 2 | SEC ↗ ×3 |
| 16 | Capital International Investors | 955.20K | -45.3% | $84.80M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 17 | UBS Group AG | 843.07K | +25.6% | $74.85M | 0.0% | ▲ Add | 3 | SEC ↗ ×4 |
| 18 | Northern Trust Corp | 674.53K | +16.5% | $59.88M | 0.0% | ▲ Add | 3 | SEC ↗ ×5 |
| 19 | Charles Schwab Investment… | 652.96K | +16.1% | $57.97M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 20 | Pictet Asset Management Holding SA | 628.14K | +27.8% | $55.77M | 0.1% | ▲ Add | 3 | SEC ↗ |
| 21 | Victory Capital Management Inc | 553.98K | +89.6% | $49.18M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 22 | UBS AM, a distinct business unit of… | 522.07K | +151.8% | $46.35M | 0.0% | ▲ Add | 3 | SEC ↗ ×9 |
| 23 | Morgan Stanley ✦ | 499.96K | +102.6% | $44.39M | 0.0% | ▲ Add | 4 | SEC ↗ ×6 |
| 24 | Voya Investment Management Llc | 431.69K | +699.9% | $38.33M | 0.0% | ▲ Add | 3 | SEC ↗ ×3 |
| 25 | Ameriprise Financial Inc | 356.08K | +123.7% | $31.61M | 0.0% | ▲ Add | 3 | SEC ↗ ×3 |
| 26 | Jennison Associates Llc | 303.18K | Nuevo | $26.92M | 0.0% | New | 1 | SEC ↗ |
| 27 | Bnp Paribas Financial Markets | 259.92K | +1295.2% | $23.08M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 28 | Bank of New York Mellon Corp | 245.19K | +28.1% | $21.77M | 0.0% | ▲ Add | 3 | SEC ↗ ×6 |
| 29 | Millennium Management ✦ | 196.71K | +34.1% | $17.46M | 0.0% | ▲ Add | 4 | SEC ↗ |
| 30 | Nuveen, LLC | 181.10K | +17.7% | $16.08M | 0.0% | ▲ Add | 3 | SEC ↗ ×3 |
| 31 | Neuberger Berman Group LLC | 180.88K | Nuevo | $16.06M | 0.0% | New | 1 | SEC ↗ ×2 |
| 32 | Deutsche Bank Ag\ | 174.46K | +35.0% | $15.49M | 0.0% | ▲ Add | 3 | SEC ↗ ×3 |
| 33 | Universal- Beteiligungs- und… | 172.92K | +1.5% | $15.35M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 34 | Balyasny Asset Management L.P. | 147.04K | +165.1% | $13.05M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 35 | Squarepoint Ops LLC | 139.60K | Nuevo | $12.39M | 0.0% | New | 1 | SEC ↗ |
| 36 | Russell Investments Group, Ltd. | 134.76K | +1256.9% | $11.96M | 0.0% | ▲ Add | 3 | SEC ↗ ×5 |
| 37 | Ensign Peak Advisors, Inc | 126.62K | -14.8% | $11.24M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 38 | Invesco Ltd. | 120.54K | -8.9% | $10.70M | 0.0% | ▼ Trim | 3 | SEC ↗ ×4 |
| 39 | Td Asset Management Inc | 115.99K | -15.6% | $10.30M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 40 | Swiss National Bank | 112.50K | +16.6% | $9.99M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 41 | Manufacturers Life Insurance… | 104.52K | -7.4% | $9.28M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 42 | Citadel Advisors ✦ | 103.10K | -4.7% | $9.15M | 0.0% | ▼ Trim | 3 | SEC ↗ ×2 |
| 43 | Rhumbline Advisers | 94.76K | +11.3% | $8.41M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 44 | Barclays Plc | 94.07K | +105.5% | $8.35M | 0.0% | ▲ Add | 3 | SEC ↗ ×2 |
| 45 | Prudential Financial Inc | 87.37K | +46.7% | $7.76M | 0.0% | ▲ Add | 2 | SEC ↗ ×2 |
| 46 | Federated Hermes, Inc. | 85.95K | Nuevo | $7.63M | 0.0% | New | 1 | SEC ↗ |
| 47 | Citigroup Inc | 82.59K | +587.9% | $7.33M | 0.0% | ▲ Add | 3 | SEC ↗ ×2 |
| 48 | Wells Fargo & Company/Mn | 82.51K | +148.4% | $7.32M | 0.0% | ▲ Add | 3 | SEC ↗ ×4 |
| 49 | Mercer Global Advisors Inc /Adv | 71.14K | +0.1% | $6.32M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 50 | Principal Financial Group Inc | 59.75K | +1289.8% | $5.30M | 0.0% | ▲ Add | 2 | SEC ↗ ×2 |
| 51 | Raymond James Financial Inc | 53.63K | +171.5% | $4.76M | 0.0% | ▲ Add | 2 | SEC ↗ ×3 |
| 52 | Alliancebernstein L.P. | 92.54K | +30.5% | $4.67M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 53 | Legal & General Group Plc | 49.14K | +9.7% | $4.36M | 0.0% | ▲ Add | 3 | SEC ↗ ×3 |
| 54 | Dimensional Fund Advisors Lp | 47.70K | 0.0% | $4.23M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 55 | Rockefeller Capital Management L.P. | 47.47K | -25.8% | $4.21M | 0.0% | ▼ Trim | 3 | SEC ↗ ×3 |
| 56 | Schroder Investment Management Group | 44.59K | -30.0% | $4.02M | 0.0% | ▼ Trim | 2 | SEC ↗ ×2 |
| 57 | State Of Wisconsin Investment Board | 45.03K | +69.8% | $4.00M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 58 | Nomura Asset Management… | 43.07K | Nuevo | $3.82M | 0.0% | New | 1 | SEC ↗ |
| 59 | Susquehanna International Group, Llp | 39.31K | +35.7% | $3.49M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 60 | MIRAE ASSET GLOBAL ETFS HOLDINGS… | 38.44K | +5.8% | $3.42M | 0.0% | ▲ Add | 3 | SEC ↗ ×2 |
| 61 | D. E. Shaw & Co. ✦ | 26.45K | Nuevo | $2.35M | 0.0% | New | 1 | SEC ↗ ×2 |
| 62 | New York State Common Retirement… | 26.16K | +17.5% | $2.32M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 63 | Zurcher Kantonalbank (Zurich… | 26.14K | +87.3% | $2.32M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 64 | Creative Planning | 25.71K | +66.0% | $2.28M | 0.0% | ▲ Add | 2 | SEC ↗ ×2 |
| 65 | AQR Capital Management ✦ | 22.94K | +9.9% | $2.04M | 0.0% | ▲ Add | 5 | SEC ↗ ×6 |
| 66 | Osaic Holdings, Inc. | 18.15K | +3543.8% | $1.61M | 0.0% | ▲ Add | 3 | SEC ↗ ×2 |
| 67 | State Board Of Administration Of… | 18.08K | +30.0% | $1.60M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 68 | Fifth Third Bancorp | 15.64K | +312660.0% | $1.39M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 69 | Allianz Asset Management GmbH | 14.10K | Nuevo | $1.25M | 0.0% | New | 1 | SEC ↗ |
| 70 | Sei Investments Co | 13.94K | +55.3% | $1.24M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 71 | Brown Advisory Inc | 13.55K | +9.3% | $1.20M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 72 | Two Sigma Investments ✦ | 12.77K | Nuevo | $1.13M | 0.0% | New | 1 | SEC ↗ |
| 73 | ProShare Advisors LLC | 12.60K | -6.7% | $1.12M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 74 | Hrt Financial Lp | 10.00K | Nuevo | $887,000 | 0.0% | New | 1 | SEC ↗ |
| 75 | First Trust Advisors Lp | 9.78K | -94.5% | $868,179 | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 76 | Man Group plc | 7.71K | -19.2% | $684,849 | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 77 | Envestnet Asset Management Inc | 7.67K | Nuevo | $680,587 | 0.0% | New | 1 | SEC ↗ |
| 78 | Allspring Global Investments… | 6.09K | Nuevo | $541,340 | 0.0% | New | 1 | SEC ↗ ×2 |
| 79 | Quantinno Capital Management LP | 6.01K | +31.9% | $534,012 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 80 | Captrust Financial Advisors | 5.02K | Nuevo | $445,942 | 0.0% | New | 1 | SEC ↗ |
| 81 | Connor, Clark & Lunn Investment… | 4.80K | Nuevo | $426,233 | 0.0% | New | 1 | SEC ↗ |
| 82 | CIBC Bancorp USA Inc. | 4.12K | Nuevo | $365,951 | 0.0% | New | 1 | SEC ↗ ×3 |
| 83 | Mirae Asset Global Investments Co.… | 3.88K | -5.2% | $344,822 | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 84 | Stifel Financial Corp | 3.01K | Nuevo | $267,316 | 0.0% | New | 1 | SEC ↗ ×2 |
| 85 | Jane Street Group, Llc | 2.91K | Nuevo | $258,261 | 0.0% | New | 1 | SEC ↗ ×2 |
| 86 | Tudor Investment Corp Et Al | 2.65K | -68.4% | $234,823 | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 87 | CIBC Asset Management Inc | 2.43K | Nuevo | $215,647 | 0.0% | New | 1 | SEC ↗ |
| 88 | Royal Bank Of Canada | 2.34K | -28.1% | $208,000 | 0.0% | ▼ Trim | 3 | SEC ↗ ×3 |
| 89 | Mitsubishi UFJ Trust & Banking Corp | 1.84K | Nuevo | $163,710 | 0.0% | New | 1 | SEC ↗ |
| 90 | Us Bancorp \De\ | 1.51K | +1453.6% | $133,791 | 0.0% | ▲ Add | 3 | SEC ↗ ×2 |
| 91 | Pnc Financial Services Group, Inc. | 914 | +643.1% | $81,145 | 0.0% | ▲ Add | 3 | SEC ↗ ×3 |
| 92 | BNP Paribas Asset Management… | 897 | +1.0% | $79,636 | 0.0% | ▲ Add | 3 | SEC ↗ |
| 93 | Pacer Advisors, Inc. | 614 | Nuevo | $55,000 | 0.0% | New | 1 | SEC ↗ |
| 94 | Optiver Holding B.V. | 400 | +38.9% | $35,512 | 0.0% | ▲ Add | 3 | SEC ↗ |
| 95 | Simplex Trading, Llc | 278 | Nuevo | $24,680 | 0.0% | New | 1 | SEC ↗ |
| 96 | Toronto Dominion Bank | 270 | Nuevo | $23,971 | 0.0% | New | 1 | SEC ↗ |
| 97 | National Bank Of Canada /Fi/ | 124 | Nuevo | $11,006 | 0.0% | New | 1 | SEC ↗ |
| 98 | Jones Financial Companies Lllp | 103 | Nuevo | $9,053 | 0.0% | New | 1 | SEC ↗ |
| 99 | Nomura Asset Management Co Ltd | 0 | — | $0 | 0.0% | Held | 3 | SEC ↗ |
«Su ponderación» = la participación de la posición en el valor de renta variable 13F declarado por ese gestor — la medida de convicción. ✦ = gestor seleccionado.
Nuevos compradores
| Adage Capital Partners | $152.91M | 0.2% |
| Holocene Advisors, LP | $90.13M | 0.2% |
| Jennison Associates Llc | $26.92M | 0.0% |
| Neuberger Berman Group LLC | $16.06M | 0.0% |
| Squarepoint Ops LLC | $12.39M | 0.0% |
| Federated Hermes, Inc. | $7.63M | 0.0% |
| Nomura Asset Management… | $3.82M | 0.0% |
| D. E. Shaw & Co. | $2.35M | 0.0% |
| Allianz Asset Management GmbH | $1.25M | 0.0% |
| Two Sigma Investments | $1.13M | 0.0% |
| Hrt Financial Lp | $887,000 | 0.0% |
| Envestnet Asset Management Inc | $680,587 | 0.0% |
Posición cerrada
| Assenagon Asset Management… | $940,555 | era 0.0% |
| Capstone Investment Advisors… | $380,166 | era 0.0% |
| Group One Trading Llc | $45,446 | era 0.0% |
Contexto de mercado completo: entre TODOS los filers 13F (datos estructurados SEC, Q1 2026): 197 tenedores, 82.12M acciones, $4.06B declarado. Este es un período diferente y anterior al de las cifras del universo rastreado que figuran arriba, y ambos nunca se mezclan.
Frecuentemente cotituladas
Qué otros valores suelen tener también los tenedores rastreados de este activo — recuentos de cotenencia, no relaciones fundamentales.
Compras en mercado abierto (P)
Sin compras en mercado abierto por parte de insiders en nuestra ventana de cobertura.
Ventas en mercado abierto (S)
Oct 01
Burrows Scott L
Officer · 229 acc. · $21,428
Oct 01
Burrows Scott L
Officer · 1.50K acc. · $135,405
Oct 01
Burrows Scott L
Officer · 3.07K acc. · $285,449
Oct 01
Burrows Scott L
Officer · 600 acc. · $53,442
Oct 01
Burrows Scott L
Officer · 2.10K acc. · $193,032
Sep 30
Burrows Scott L
Officer · 17.50K acc. · $1.57M
Sep 02
Burrows Scott L
Officer · 18.23K acc. · $1.63M
Sep 02
King-Jones Heidy
Officer · 400 acc. · $36,000
Sep 01
King-Jones Heidy
Officer · 16.55K acc. · $1.44M
Sep 01
Burrows Scott L
Officer · 900 acc. · $77,625
Las adjudicaciones, ejercicios y retenciones fiscales nunca se contabilizan aquí como compras o ventas. Metodología
Oct 09
SC 13D/A — Fairmount Funds Management LLC
9.2% de clase · Ver presentación original ante la SEC ↗
Oct 01
SC 13G — Paradigm Biocapital Advisors LP
Aug 14
SC 13G/A — RTW INVESTMENTS, LP
Aug 14
SC 13G/A — PERCEPTIVE ADVISORS LLC
Jun 23
SC 13D/A — Fairmount Funds Management LLC
9.2% de clase · Ver presentación original ante la SEC ↗
Procedencia: Participación a partir de posiciones en acciones ordinarias de 13F procesadas (universo rastreado, conjuntos comparables para cambios); filas de iniciados de los Formularios 3/4/5; participaciones de los Schedules 13D/13G; cada filing enlaza con su original en SEC EDGAR.
Período de reporte: Q2 2026 ·
Metodología ·
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