Registro do valor mobiliário · trimestre arquivado
SYRE
Spyre Therapeutics, Inc. · Healthcare · Biotechnology
69Detentores rastreados
+2Δ titulares
41.90MAções mantidas
$1.37BValor reportado
+2Novas posições
−0Saídas
Dados de momentum (gestores comparáveis):
amplitude de detentores +3.0% ·
fluxo de ações +18.7% ·
novas posições líquidas +2.9%
— fórmula
Acumulação ampla — aumento de ações entre um número maior de detentores
Todos os dados de participação: apenas gestores 13F rastreados, posições em ações ordinárias, período de referência Q4 2025
Participação ao longo do tempo
| Trimestre | Detentores | Δ | Ações | Valor reportado | Novo | Saídas |
|---|---|---|---|---|---|---|
| Q2 2026 | 99 | +22 | 55.43M | $4.93B | +25 | −3 |
| Q1 2026 | 80 | +10 | 41.69M | $2.10B | +12 | −2 |
| Q4 2025 | 69 | +2 | 41.90M | $1.37B | +2 | — |
| Q3 2025 | 13 | -1 | 23.21M | $388.94M | +1 | −2 |
| Q2 2025 | 11 | 0 | 22.40M | $335.38M | +2 | −2 |
| Q1 2025 | 8 | -2 | 6.01M | $96.96M | — | −2 |
| Q4 2024 | 10 | +1 | 7.67M | $178.64M | +2 | −1 |
| Q3 2024 | 8 | 0 | 4.78M | $140.58M | +1 | −1 |
| Q2 2024 | 8 | — | 3.96M | $93.00M | — | — |
Quem detém · Q4 2025
| # | Gestor | Ações | Δ ações | Valor | Seu peso | Detido | ||
|---|---|---|---|---|---|---|---|---|
| 1 | Fidelity (FMR) ✦ | 11.64M | +28.5% | $381.29M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 2 | Fidelity (FMR) ✦ | 11.64M | +28.5% | $381.29M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 3 | Fidelity (FMR) ✦ | 11.64M | +28.5% | $381.29M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 4 | BlackRock ✦ (passivo) | 5.52M | +38.6% | $180.90M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 5 | BlackRock ✦ (passivo) | 5.52M | +38.6% | $180.90M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 6 | BlackRock ✦ (passivo) | 5.52M | +38.6% | $180.90M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 7 | BlackRock ✦ (passivo) | 5.52M | +38.6% | $180.90M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 8 | BlackRock ✦ (passivo) | 5.52M | +38.6% | $180.90M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 9 | BlackRock ✦ (passivo) | 5.52M | +38.6% | $180.90M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 10 | BlackRock ✦ (passivo) | 5.52M | +38.6% | $180.90M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 11 | BlackRock ✦ (passivo) | 5.52M | +38.6% | $180.90M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 12 | BlackRock ✦ (passivo) | 5.52M | +38.6% | $180.90M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 13 | BlackRock ✦ (passivo) | 5.52M | +38.6% | $180.90M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 14 | BlackRock ✦ (passivo) | 5.52M | +38.6% | $180.90M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 15 | BlackRock ✦ (passivo) | 5.52M | +38.6% | $180.90M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 16 | The Vanguard Group ✦ (passivo) | 4.04M | +32.3% | $132.19M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 17 | The Vanguard Group ✦ (passivo) | 4.04M | +32.3% | $132.19M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 18 | The Vanguard Group ✦ (passivo) | 4.04M | +32.3% | $132.19M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 19 | The Vanguard Group ✦ (passivo) | 4.04M | +32.3% | $132.19M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 20 | The Vanguard Group ✦ (passivo) | 4.04M | +32.3% | $132.19M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 21 | Capital International Investors | 3.49M | — | $114.42M | 0.0% | n/c | 1 | SEC ↗ |
| 22 | State Street Global Advisors ✦ (passivo) | 2.26M | +26.8% | $74.13M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 23 | Janus Henderson Group Plc | 1.83M | — | $59.92M | 0.0% | n/c | 1 | SEC ↗ |
| 24 | Janus Henderson Group Plc | 1.83M | — | $59.92M | 0.0% | n/c | 1 | SEC ↗ |
| 25 | Geode Capital Management ✦ (passivo) | 1.66M | +35.4% | $54.36M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 26 | Geode Capital Management ✦ (passivo) | 1.66M | +35.4% | $54.36M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 27 | T. Rowe Price ✦ | 1.60M | +158.1% | $52.48M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 28 | T. Rowe Price ✦ | 1.60M | +158.1% | $52.48M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 29 | Wellington Management ✦ | 1.55M | -5.5% | $50.75M | 0.0% | ▼ Trim | 7 | SEC ↗ |
| 30 | Wellington Management ✦ | 1.55M | -5.5% | $50.75M | 0.0% | ▼ Trim | 7 | SEC ↗ |
| 31 | Wellington Management ✦ | 1.55M | -5.5% | $50.75M | 0.0% | ▼ Trim | 7 | SEC ↗ |
| 32 | Wellington Management ✦ | 1.55M | -5.5% | $50.75M | 0.0% | ▼ Trim | 7 | SEC ↗ |
| 33 | Wellington Management ✦ | 1.55M | -5.5% | $50.75M | 0.0% | ▼ Trim | 7 | SEC ↗ |
| 34 | Wellington Management ✦ | 1.55M | -5.5% | $50.75M | 0.0% | ▼ Trim | 7 | SEC ↗ |
| 35 | Wellington Management ✦ | 1.55M | -5.5% | $50.75M | 0.0% | ▼ Trim | 7 | SEC ↗ |
| 36 | Franklin Resources Inc | 1.11M | — | $36.34M | 0.0% | n/c | 1 | SEC ↗ |
| 37 | Franklin Resources Inc | 1.11M | — | $36.34M | 0.0% | n/c | 1 | SEC ↗ |
| 38 | Pictet Asset Management Holding SA | 913.96K | — | $29.94M | 0.0% | n/c | 1 | SEC ↗ |
| 39 | UBS Group AG | 680.57K | — | $22.30M | 0.0% | n/c | 1 | SEC ↗ |
| 40 | UBS Group AG | 680.57K | — | $22.30M | 0.0% | n/c | 1 | SEC ↗ |
| 41 | UBS Group AG | 680.57K | — | $22.30M | 0.0% | n/c | 1 | SEC ↗ |
| 42 | Point72 Asset Management ✦ | 662.35K | Novo | $21.70M | 0.0% | New | 1 | SEC ↗ |
| 43 | Charles Schwab Investment… | 574.62K | — | $18.82M | 0.0% | n/c | 1 | SEC ↗ |
| 44 | Northern Trust Corp | 561.02K | — | $18.38M | 0.0% | n/c | 1 | SEC ↗ |
| 45 | Northern Trust Corp | 561.02K | — | $18.38M | 0.0% | n/c | 1 | SEC ↗ |
| 46 | Northern Trust Corp | 561.02K | — | $18.38M | 0.0% | n/c | 1 | SEC ↗ |
| 47 | Northern Trust Corp | 561.02K | — | $18.38M | 0.0% | n/c | 1 | SEC ↗ |
| 48 | Northern Trust Corp | 561.02K | — | $18.38M | 0.0% | n/c | 1 | SEC ↗ |
| 49 | Northern Trust Corp | 561.02K | — | $18.38M | 0.0% | n/c | 1 | SEC ↗ |
| 50 | Bank Of America Corp /De/ | 419.73K | — | $13.75M | 0.0% | n/c | 1 | SEC ↗ |
| 51 | Bank Of America Corp /De/ | 419.73K | — | $13.75M | 0.0% | n/c | 1 | SEC ↗ |
| 52 | Bank Of America Corp /De/ | 419.73K | — | $13.75M | 0.0% | n/c | 1 | SEC ↗ |
| 53 | Goldman Sachs Group ✦ | 275.06K | -16.5% | $9.01M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 54 | Goldman Sachs Group ✦ | 275.06K | -16.5% | $9.01M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 55 | Capital World Investors ✦ | 200.17K | 0.0% | $6.56M | 0.0% | Held | 5 | SEC ↗ |
| 56 | Bank of New York Mellon Corp | 192.83K | — | $6.32M | 0.0% | n/c | 1 | SEC ↗ |
| 57 | Bank of New York Mellon Corp | 192.83K | — | $6.32M | 0.0% | n/c | 1 | SEC ↗ |
| 58 | Bank of New York Mellon Corp | 192.83K | — | $6.32M | 0.0% | n/c | 1 | SEC ↗ |
| 59 | Bank of New York Mellon Corp | 192.83K | — | $6.32M | 0.0% | n/c | 1 | SEC ↗ |
| 60 | Morgan Stanley ✦ | 182.73K | -45.4% | $5.99M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 61 | Morgan Stanley ✦ | 182.73K | -45.4% | $5.99M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 62 | Morgan Stanley ✦ | 182.73K | -45.4% | $5.99M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 63 | Morgan Stanley ✦ | 182.73K | -45.4% | $5.99M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 64 | Morgan Stanley ✦ | 182.73K | -45.4% | $5.99M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 65 | Morgan Stanley ✦ | 182.73K | -45.4% | $5.99M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 66 | Barclays Plc | 182.52K | — | $5.98M | 0.0% | n/c | 1 | SEC ↗ |
| 67 | Barclays Plc | 182.52K | — | $5.98M | 0.0% | n/c | 1 | SEC ↗ |
| 68 | Universal- Beteiligungs- und… | 171.21K | — | $5.61M | 0.0% | n/c | 1 | SEC ↗ |
| 69 | Nuveen, LLC | 150.98K | — | $4.95M | 0.0% | n/c | 1 | SEC ↗ |
| 70 | Nuveen, LLC | 150.98K | — | $4.95M | 0.0% | n/c | 1 | SEC ↗ |
| 71 | Invesco Ltd. | 150.93K | — | $4.94M | 0.0% | n/c | 1 | SEC ↗ |
| 72 | Invesco Ltd. | 150.93K | — | $4.94M | 0.0% | n/c | 1 | SEC ↗ |
| 73 | Invesco Ltd. | 150.93K | — | $4.94M | 0.0% | n/c | 1 | SEC ↗ |
| 74 | Invesco Ltd. | 150.93K | — | $4.94M | 0.0% | n/c | 1 | SEC ↗ |
| 75 | Td Asset Management Inc | 149.82K | — | $4.91M | 0.0% | n/c | 1 | SEC ↗ |
| 76 | Victory Capital Management Inc | 146.08K | — | $4.79M | 0.0% | n/c | 1 | SEC ↗ |
| 77 | Manufacturers Life Insurance… | 129.01K | — | $4.14M | 0.0% | n/c | 1 | SEC ↗ |
| 78 | Deutsche Bank Ag\ | 121.94K | — | $3.99M | 0.0% | n/c | 1 | SEC ↗ |
| 79 | Deutsche Bank Ag\ | 121.94K | — | $3.99M | 0.0% | n/c | 1 | SEC ↗ |
| 80 | Deutsche Bank Ag\ | 121.94K | — | $3.99M | 0.0% | n/c | 1 | SEC ↗ |
| 81 | Mercer Global Advisors Inc /Adv | 106.32K | — | $3.48M | 0.0% | n/c | 1 | SEC ↗ |
| 82 | Citigroup Inc | 100.06K | — | $3.28M | 0.0% | n/c | 1 | SEC ↗ |
| 83 | Citigroup Inc | 100.06K | — | $3.28M | 0.0% | n/c | 1 | SEC ↗ |
| 84 | Swiss National Bank | 96.50K | — | $3.16M | 0.0% | n/c | 1 | SEC ↗ |
| 85 | Rhumbline Advisers | 82.96K | — | $2.72M | 0.0% | n/c | 1 | SEC ↗ |
| 86 | Wells Fargo & Company/Mn | 82.42K | — | $2.70M | 0.0% | n/c | 1 | SEC ↗ |
| 87 | Wells Fargo & Company/Mn | 82.42K | — | $2.70M | 0.0% | n/c | 1 | SEC ↗ |
| 88 | Dimensional Fund Advisors Lp | 77.29K | — | $2.53M | 0.0% | n/c | 1 | SEC ↗ |
| 89 | Millennium Management ✦ | 76.19K | -81.3% | $2.50M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 90 | Balyasny Asset Management L.P. | 73.47K | — | $2.41M | 0.0% | n/c | 1 | SEC ↗ |
| 91 | Alliancebernstein L.P. | 67.50K | — | $2.21M | 0.0% | n/c | 1 | SEC ↗ |
| 92 | Citadel Advisors ✦ | 63.90K | Novo | $2.09M | 0.0% | New | 1 | SEC ↗ |
| 93 | JPMorgan Chase ✦ | 62.95K | -88.6% | $2.06M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 94 | JPMorgan Chase ✦ | 62.95K | -88.6% | $2.06M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 95 | JPMorgan Chase ✦ | 62.95K | -88.6% | $2.06M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 96 | JPMorgan Chase ✦ | 62.95K | -88.6% | $2.06M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 97 | UBS AM, a distinct business unit of… | 62.22K | — | $2.04M | 0.0% | n/c | 1 | SEC ↗ |
| 98 | UBS AM, a distinct business unit of… | 62.22K | — | $2.04M | 0.0% | n/c | 1 | SEC ↗ |
| 99 | UBS AM, a distinct business unit of… | 62.22K | — | $2.04M | 0.0% | n/c | 1 | SEC ↗ |
| 100 | Legal & General Group Plc | 56.45K | — | $1.85M | 0.0% | n/c | 1 | SEC ↗ |
"Peso do gestor" = a participação da posição no valor total de ações 13F reportado pelo gestor — a medida de convicção. ✦ = gestor curado.
Novos compradores
| Point72 Asset Management | $21.70M | 0.0% |
| Citadel Advisors | $2.09M | 0.0% |
Encerrado
| Nenhuma saída rastreada neste trimestre. |
Contexto de mercado completo: entre TODOS os filers 13F (dados estruturados da SEC, Q1 2026): 197 detentores, 82.12M ações, $4.06B reportado. Este é um período diferente e mais antigo do que os dados do universo rastreado acima, e os dois nunca são combinados.
Frequentemente detidos em conjunto
O que os detentores rastreados deste título mais frequentemente também detêm — contagens de participação compartilhada, não relações fundamentais.
Compras no mercado aberto (P)
Nenhuma compra direta no mercado por insiders em nossa janela de cobertura.
Vendas no mercado aberto (S)
Aug 07
Albers Jeffrey W.
Director · 5.00K ações · $522,350
Aug 07
Albers Jeffrey W.
Director · 8.00K ações · $835,040
Aug 07
Albers Jeffrey W.
Director · 10.00K ações · $1.05M
Prêmios, exercícios e retenção fiscal nunca são contabilizados como compras ou vendas aqui. Metodologia
Aug 14
SC 13G/A — RTW INVESTMENTS, LP
Aug 14
SC 13G/A — PERCEPTIVE ADVISORS LLC
Jun 23
SC 13D/A — Fairmount Funds Management LLC
9.2% da classe · Ver filing original na SEC ↗
Proveniência: Participação a partir de posições em ações ordinárias de 13F analisadas (universo rastreado, conjuntos comparáveis para variações); linhas de insiders dos Formulários 3/4/5; participações dos Schedules 13D/13G; cada filing está vinculado ao original no SEC EDGAR.
Período de referência: Q4 2025 ·
Metodologia ·
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