Effectdossier · gearchiveerd kwartaal
SYRE
Spyre Therapeutics, Inc. · Healthcare · Biotechnology
69Gevolgde houders
+2Δ houders
41.90MGehouden aandelen
$1.37BGerapporteerde waarde
+2Nieuwe posities
−0Uitstappen
Momentum-inputs (vergelijkbare managers):
breedte van houders +3.0% ·
aandelenstroom +18.7% ·
netto nieuwe posities +2.9%
— formule
Brede accumulatie — stijgende aandelen bij meer houders
Alle eigendomscijfers: uitsluitend gevolgde 13F-managers, posities in gewone aandelen, rapportageperiode Q4 2025
Eigendom in de tijd
| Kwartaal | Houders | Δ | Aandelen | Gerapporteerde waarde | Nieuw | Uitstappen |
|---|---|---|---|---|---|---|
| Q2 2026 | 99 | +22 | 55.43M | $4.93B | +25 | −3 |
| Q1 2026 | 80 | +10 | 41.69M | $2.10B | +12 | −2 |
| Q4 2025 | 69 | +2 | 41.90M | $1.37B | +2 | — |
| Q3 2025 | 13 | -1 | 23.21M | $388.94M | +1 | −2 |
| Q2 2025 | 11 | 0 | 22.40M | $335.38M | +2 | −2 |
| Q1 2025 | 8 | -2 | 6.01M | $96.96M | — | −2 |
| Q4 2024 | 10 | +1 | 7.67M | $178.64M | +2 | −1 |
| Q3 2024 | 8 | 0 | 4.78M | $140.58M | +1 | −1 |
| Q2 2024 | 8 | — | 3.96M | $93.00M | — | — |
Wie het bezit · Q4 2025
| # | Manager | Aandelen | Δ aandelen | Waarde | Hun gewicht | Gehouden | ||
|---|---|---|---|---|---|---|---|---|
| 1 | Fidelity (FMR) ✦ | 11.64M | +28.5% | $381.29M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 2 | Fidelity (FMR) ✦ | 11.64M | +28.5% | $381.29M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 3 | Fidelity (FMR) ✦ | 11.64M | +28.5% | $381.29M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 4 | BlackRock ✦ (passief) | 5.52M | +38.6% | $180.90M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 5 | BlackRock ✦ (passief) | 5.52M | +38.6% | $180.90M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 6 | BlackRock ✦ (passief) | 5.52M | +38.6% | $180.90M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 7 | BlackRock ✦ (passief) | 5.52M | +38.6% | $180.90M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 8 | BlackRock ✦ (passief) | 5.52M | +38.6% | $180.90M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 9 | BlackRock ✦ (passief) | 5.52M | +38.6% | $180.90M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 10 | BlackRock ✦ (passief) | 5.52M | +38.6% | $180.90M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 11 | BlackRock ✦ (passief) | 5.52M | +38.6% | $180.90M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 12 | BlackRock ✦ (passief) | 5.52M | +38.6% | $180.90M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 13 | BlackRock ✦ (passief) | 5.52M | +38.6% | $180.90M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 14 | BlackRock ✦ (passief) | 5.52M | +38.6% | $180.90M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 15 | BlackRock ✦ (passief) | 5.52M | +38.6% | $180.90M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 16 | The Vanguard Group ✦ (passief) | 4.04M | +32.3% | $132.19M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 17 | The Vanguard Group ✦ (passief) | 4.04M | +32.3% | $132.19M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 18 | The Vanguard Group ✦ (passief) | 4.04M | +32.3% | $132.19M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 19 | The Vanguard Group ✦ (passief) | 4.04M | +32.3% | $132.19M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 20 | The Vanguard Group ✦ (passief) | 4.04M | +32.3% | $132.19M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 21 | Capital International Investors | 3.49M | — | $114.42M | 0.0% | n/c | 1 | SEC ↗ |
| 22 | State Street Global Advisors ✦ (passief) | 2.26M | +26.8% | $74.13M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 23 | Janus Henderson Group Plc | 1.83M | — | $59.92M | 0.0% | n/c | 1 | SEC ↗ |
| 24 | Janus Henderson Group Plc | 1.83M | — | $59.92M | 0.0% | n/c | 1 | SEC ↗ |
| 25 | Geode Capital Management ✦ (passief) | 1.66M | +35.4% | $54.36M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 26 | Geode Capital Management ✦ (passief) | 1.66M | +35.4% | $54.36M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 27 | T. Rowe Price ✦ | 1.60M | +158.1% | $52.48M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 28 | T. Rowe Price ✦ | 1.60M | +158.1% | $52.48M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 29 | Wellington Management ✦ | 1.55M | -5.5% | $50.75M | 0.0% | ▼ Trim | 7 | SEC ↗ |
| 30 | Wellington Management ✦ | 1.55M | -5.5% | $50.75M | 0.0% | ▼ Trim | 7 | SEC ↗ |
| 31 | Wellington Management ✦ | 1.55M | -5.5% | $50.75M | 0.0% | ▼ Trim | 7 | SEC ↗ |
| 32 | Wellington Management ✦ | 1.55M | -5.5% | $50.75M | 0.0% | ▼ Trim | 7 | SEC ↗ |
| 33 | Wellington Management ✦ | 1.55M | -5.5% | $50.75M | 0.0% | ▼ Trim | 7 | SEC ↗ |
| 34 | Wellington Management ✦ | 1.55M | -5.5% | $50.75M | 0.0% | ▼ Trim | 7 | SEC ↗ |
| 35 | Wellington Management ✦ | 1.55M | -5.5% | $50.75M | 0.0% | ▼ Trim | 7 | SEC ↗ |
| 36 | Franklin Resources Inc | 1.11M | — | $36.34M | 0.0% | n/c | 1 | SEC ↗ |
| 37 | Franklin Resources Inc | 1.11M | — | $36.34M | 0.0% | n/c | 1 | SEC ↗ |
| 38 | Pictet Asset Management Holding SA | 913.96K | — | $29.94M | 0.0% | n/c | 1 | SEC ↗ |
| 39 | UBS Group AG | 680.57K | — | $22.30M | 0.0% | n/c | 1 | SEC ↗ |
| 40 | UBS Group AG | 680.57K | — | $22.30M | 0.0% | n/c | 1 | SEC ↗ |
| 41 | UBS Group AG | 680.57K | — | $22.30M | 0.0% | n/c | 1 | SEC ↗ |
| 42 | Point72 Asset Management ✦ | 662.35K | Nieuw | $21.70M | 0.0% | New | 1 | SEC ↗ |
| 43 | Charles Schwab Investment… | 574.62K | — | $18.82M | 0.0% | n/c | 1 | SEC ↗ |
| 44 | Northern Trust Corp | 561.02K | — | $18.38M | 0.0% | n/c | 1 | SEC ↗ |
| 45 | Northern Trust Corp | 561.02K | — | $18.38M | 0.0% | n/c | 1 | SEC ↗ |
| 46 | Northern Trust Corp | 561.02K | — | $18.38M | 0.0% | n/c | 1 | SEC ↗ |
| 47 | Northern Trust Corp | 561.02K | — | $18.38M | 0.0% | n/c | 1 | SEC ↗ |
| 48 | Northern Trust Corp | 561.02K | — | $18.38M | 0.0% | n/c | 1 | SEC ↗ |
| 49 | Northern Trust Corp | 561.02K | — | $18.38M | 0.0% | n/c | 1 | SEC ↗ |
| 50 | Bank Of America Corp /De/ | 419.73K | — | $13.75M | 0.0% | n/c | 1 | SEC ↗ |
| 51 | Bank Of America Corp /De/ | 419.73K | — | $13.75M | 0.0% | n/c | 1 | SEC ↗ |
| 52 | Bank Of America Corp /De/ | 419.73K | — | $13.75M | 0.0% | n/c | 1 | SEC ↗ |
| 53 | Goldman Sachs Group ✦ | 275.06K | -16.5% | $9.01M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 54 | Goldman Sachs Group ✦ | 275.06K | -16.5% | $9.01M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 55 | Capital World Investors ✦ | 200.17K | 0.0% | $6.56M | 0.0% | Held | 5 | SEC ↗ |
| 56 | Bank of New York Mellon Corp | 192.83K | — | $6.32M | 0.0% | n/c | 1 | SEC ↗ |
| 57 | Bank of New York Mellon Corp | 192.83K | — | $6.32M | 0.0% | n/c | 1 | SEC ↗ |
| 58 | Bank of New York Mellon Corp | 192.83K | — | $6.32M | 0.0% | n/c | 1 | SEC ↗ |
| 59 | Bank of New York Mellon Corp | 192.83K | — | $6.32M | 0.0% | n/c | 1 | SEC ↗ |
| 60 | Morgan Stanley ✦ | 182.73K | -45.4% | $5.99M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 61 | Morgan Stanley ✦ | 182.73K | -45.4% | $5.99M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 62 | Morgan Stanley ✦ | 182.73K | -45.4% | $5.99M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 63 | Morgan Stanley ✦ | 182.73K | -45.4% | $5.99M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 64 | Morgan Stanley ✦ | 182.73K | -45.4% | $5.99M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 65 | Morgan Stanley ✦ | 182.73K | -45.4% | $5.99M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 66 | Barclays Plc | 182.52K | — | $5.98M | 0.0% | n/c | 1 | SEC ↗ |
| 67 | Barclays Plc | 182.52K | — | $5.98M | 0.0% | n/c | 1 | SEC ↗ |
| 68 | Universal- Beteiligungs- und… | 171.21K | — | $5.61M | 0.0% | n/c | 1 | SEC ↗ |
| 69 | Nuveen, LLC | 150.98K | — | $4.95M | 0.0% | n/c | 1 | SEC ↗ |
| 70 | Nuveen, LLC | 150.98K | — | $4.95M | 0.0% | n/c | 1 | SEC ↗ |
| 71 | Invesco Ltd. | 150.93K | — | $4.94M | 0.0% | n/c | 1 | SEC ↗ |
| 72 | Invesco Ltd. | 150.93K | — | $4.94M | 0.0% | n/c | 1 | SEC ↗ |
| 73 | Invesco Ltd. | 150.93K | — | $4.94M | 0.0% | n/c | 1 | SEC ↗ |
| 74 | Invesco Ltd. | 150.93K | — | $4.94M | 0.0% | n/c | 1 | SEC ↗ |
| 75 | Td Asset Management Inc | 149.82K | — | $4.91M | 0.0% | n/c | 1 | SEC ↗ |
| 76 | Victory Capital Management Inc | 146.08K | — | $4.79M | 0.0% | n/c | 1 | SEC ↗ |
| 77 | Manufacturers Life Insurance… | 129.01K | — | $4.14M | 0.0% | n/c | 1 | SEC ↗ |
| 78 | Deutsche Bank Ag\ | 121.94K | — | $3.99M | 0.0% | n/c | 1 | SEC ↗ |
| 79 | Deutsche Bank Ag\ | 121.94K | — | $3.99M | 0.0% | n/c | 1 | SEC ↗ |
| 80 | Deutsche Bank Ag\ | 121.94K | — | $3.99M | 0.0% | n/c | 1 | SEC ↗ |
| 81 | Mercer Global Advisors Inc /Adv | 106.32K | — | $3.48M | 0.0% | n/c | 1 | SEC ↗ |
| 82 | Citigroup Inc | 100.06K | — | $3.28M | 0.0% | n/c | 1 | SEC ↗ |
| 83 | Citigroup Inc | 100.06K | — | $3.28M | 0.0% | n/c | 1 | SEC ↗ |
| 84 | Swiss National Bank | 96.50K | — | $3.16M | 0.0% | n/c | 1 | SEC ↗ |
| 85 | Rhumbline Advisers | 82.96K | — | $2.72M | 0.0% | n/c | 1 | SEC ↗ |
| 86 | Wells Fargo & Company/Mn | 82.42K | — | $2.70M | 0.0% | n/c | 1 | SEC ↗ |
| 87 | Wells Fargo & Company/Mn | 82.42K | — | $2.70M | 0.0% | n/c | 1 | SEC ↗ |
| 88 | Dimensional Fund Advisors Lp | 77.29K | — | $2.53M | 0.0% | n/c | 1 | SEC ↗ |
| 89 | Millennium Management ✦ | 76.19K | -81.3% | $2.50M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 90 | Balyasny Asset Management L.P. | 73.47K | — | $2.41M | 0.0% | n/c | 1 | SEC ↗ |
| 91 | Alliancebernstein L.P. | 67.50K | — | $2.21M | 0.0% | n/c | 1 | SEC ↗ |
| 92 | Citadel Advisors ✦ | 63.90K | Nieuw | $2.09M | 0.0% | New | 1 | SEC ↗ |
| 93 | JPMorgan Chase ✦ | 62.95K | -88.6% | $2.06M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 94 | JPMorgan Chase ✦ | 62.95K | -88.6% | $2.06M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 95 | JPMorgan Chase ✦ | 62.95K | -88.6% | $2.06M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 96 | JPMorgan Chase ✦ | 62.95K | -88.6% | $2.06M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 97 | UBS AM, a distinct business unit of… | 62.22K | — | $2.04M | 0.0% | n/c | 1 | SEC ↗ |
| 98 | UBS AM, a distinct business unit of… | 62.22K | — | $2.04M | 0.0% | n/c | 1 | SEC ↗ |
| 99 | UBS AM, a distinct business unit of… | 62.22K | — | $2.04M | 0.0% | n/c | 1 | SEC ↗ |
| 100 | Legal & General Group Plc | 56.45K | — | $1.85M | 0.0% | n/c | 1 | SEC ↗ |
"Hun gewicht" = het aandeel van de positie in de gerapporteerde 13F-aandelenwaarde van die beheerder — de overtuigingsmaatstaf. ✦ = gecureerde beheerder.
Nieuwe kopers
| Point72 Asset Management | $21.70M | 0.0% |
| Citadel Advisors | $2.09M | 0.0% |
Verlaten
| Geen bijgehouden uitstappen dit kwartaal. |
Volledige marktcontext: over ALLE 13F-indieners (SEC gestructureerde data, Q1 2026): 197 houders, 82.12M aandelen, $4.06B gerapporteerd. Dit betreft een andere, oudere periode dan de bovenstaande cijfers van het gevolgde universum; beide worden nooit gecombineerd.
Vaak gezamenlijk in bezit
Wat de gevolgde houders van dit effect verder het vaakst bezitten — aantallen gedeeld eigendom, geen fundamentele relaties.
Open-market aankopen (P)
Geen open-market insider-aankopen in ons dekkingsvenster.
Open-market verkopen (S)
Aug 07
Albers Jeffrey W.
Director · 5.00K aand · $522,350
Aug 07
Albers Jeffrey W.
Director · 8.00K aand · $835,040
Aug 07
Albers Jeffrey W.
Director · 10.00K aand · $1.05M
Toekenningen, uitoefeningen en belastinginhoudingen worden hier nooit meegeteld als aankopen of verkopen. Methodologie
Aug 14
SC 13G/A — RTW INVESTMENTS, LP
Aug 14
SC 13G/A — PERCEPTIVE ADVISORS LLC
Jun 23
SC 13D/A — Fairmount Funds Management LLC
9.2% van klasse · Originele SEC-indiening bekijken ↗
Herkomst: Eigendom op basis van geparseerde 13F common-stockposities (gevolgde universum, vergelijkbare sets voor wijzigingen); insider-rijen afkomstig van formulieren 3/4/5; belangen uit Schedules 13D/13G; elke indiening verwijst naar het origineel op SEC EDGAR.
Rapportageperiode: Q4 2025 ·
Methodologie ·
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