Scheda del titolo · trimestre archiviato
SYRE
Spyre Therapeutics, Inc. · Healthcare · Biotechnology
69Holder monitorati
+2Δ titolari
41.90MQuote detenute
$1.37BValore dichiarato
+2Nuove posizioni
−0Uscite
Input di momentum (manager comparabili):
ampiezza dei detentori +3.0% ·
flusso azionario +18.7% ·
nuove posizioni nette +2.9%
— formula
Accumulo diffuso — azioni in aumento tra un maggior numero di detentori
Tutte le cifre di proprietà: solo gestori 13F monitorati, posizioni in azioni ordinarie, periodo di riferimento Q4 2025
Proprietà nel tempo
| Trimestre | Detentori | Δ | Quote | Valore dichiarato | Nuovo | Uscite |
|---|---|---|---|---|---|---|
| Q2 2026 | 99 | +22 | 55.43M | $4.93B | +25 | −3 |
| Q1 2026 | 80 | +10 | 41.69M | $2.10B | +12 | −2 |
| Q4 2025 | 69 | +2 | 41.90M | $1.37B | +2 | — |
| Q3 2025 | 13 | -1 | 23.21M | $388.94M | +1 | −2 |
| Q2 2025 | 11 | 0 | 22.40M | $335.38M | +2 | −2 |
| Q1 2025 | 8 | -2 | 6.01M | $96.96M | — | −2 |
| Q4 2024 | 10 | +1 | 7.67M | $178.64M | +2 | −1 |
| Q3 2024 | 8 | 0 | 4.78M | $140.58M | +1 | −1 |
| Q2 2024 | 8 | — | 3.96M | $93.00M | — | — |
Chi lo detiene · Q4 2025
| # | Gestore | Quote | Δ azioni | Valore | Il loro peso | Detenuto | ||
|---|---|---|---|---|---|---|---|---|
| 1 | Fidelity (FMR) ✦ | 11.64M | +28.5% | $381.29M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 2 | Fidelity (FMR) ✦ | 11.64M | +28.5% | $381.29M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 3 | Fidelity (FMR) ✦ | 11.64M | +28.5% | $381.29M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 4 | BlackRock ✦ (passivo) | 5.52M | +38.6% | $180.90M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 5 | BlackRock ✦ (passivo) | 5.52M | +38.6% | $180.90M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 6 | BlackRock ✦ (passivo) | 5.52M | +38.6% | $180.90M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 7 | BlackRock ✦ (passivo) | 5.52M | +38.6% | $180.90M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 8 | BlackRock ✦ (passivo) | 5.52M | +38.6% | $180.90M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 9 | BlackRock ✦ (passivo) | 5.52M | +38.6% | $180.90M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 10 | BlackRock ✦ (passivo) | 5.52M | +38.6% | $180.90M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 11 | BlackRock ✦ (passivo) | 5.52M | +38.6% | $180.90M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 12 | BlackRock ✦ (passivo) | 5.52M | +38.6% | $180.90M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 13 | BlackRock ✦ (passivo) | 5.52M | +38.6% | $180.90M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 14 | BlackRock ✦ (passivo) | 5.52M | +38.6% | $180.90M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 15 | BlackRock ✦ (passivo) | 5.52M | +38.6% | $180.90M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 16 | The Vanguard Group ✦ (passivo) | 4.04M | +32.3% | $132.19M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 17 | The Vanguard Group ✦ (passivo) | 4.04M | +32.3% | $132.19M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 18 | The Vanguard Group ✦ (passivo) | 4.04M | +32.3% | $132.19M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 19 | The Vanguard Group ✦ (passivo) | 4.04M | +32.3% | $132.19M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 20 | The Vanguard Group ✦ (passivo) | 4.04M | +32.3% | $132.19M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 21 | Capital International Investors | 3.49M | — | $114.42M | 0.0% | n/c | 1 | SEC ↗ |
| 22 | State Street Global Advisors ✦ (passivo) | 2.26M | +26.8% | $74.13M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 23 | Janus Henderson Group Plc | 1.83M | — | $59.92M | 0.0% | n/c | 1 | SEC ↗ |
| 24 | Janus Henderson Group Plc | 1.83M | — | $59.92M | 0.0% | n/c | 1 | SEC ↗ |
| 25 | Geode Capital Management ✦ (passivo) | 1.66M | +35.4% | $54.36M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 26 | Geode Capital Management ✦ (passivo) | 1.66M | +35.4% | $54.36M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 27 | T. Rowe Price ✦ | 1.60M | +158.1% | $52.48M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 28 | T. Rowe Price ✦ | 1.60M | +158.1% | $52.48M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 29 | Wellington Management ✦ | 1.55M | -5.5% | $50.75M | 0.0% | ▼ Trim | 7 | SEC ↗ |
| 30 | Wellington Management ✦ | 1.55M | -5.5% | $50.75M | 0.0% | ▼ Trim | 7 | SEC ↗ |
| 31 | Wellington Management ✦ | 1.55M | -5.5% | $50.75M | 0.0% | ▼ Trim | 7 | SEC ↗ |
| 32 | Wellington Management ✦ | 1.55M | -5.5% | $50.75M | 0.0% | ▼ Trim | 7 | SEC ↗ |
| 33 | Wellington Management ✦ | 1.55M | -5.5% | $50.75M | 0.0% | ▼ Trim | 7 | SEC ↗ |
| 34 | Wellington Management ✦ | 1.55M | -5.5% | $50.75M | 0.0% | ▼ Trim | 7 | SEC ↗ |
| 35 | Wellington Management ✦ | 1.55M | -5.5% | $50.75M | 0.0% | ▼ Trim | 7 | SEC ↗ |
| 36 | Franklin Resources Inc | 1.11M | — | $36.34M | 0.0% | n/c | 1 | SEC ↗ |
| 37 | Franklin Resources Inc | 1.11M | — | $36.34M | 0.0% | n/c | 1 | SEC ↗ |
| 38 | Pictet Asset Management Holding SA | 913.96K | — | $29.94M | 0.0% | n/c | 1 | SEC ↗ |
| 39 | UBS Group AG | 680.57K | — | $22.30M | 0.0% | n/c | 1 | SEC ↗ |
| 40 | UBS Group AG | 680.57K | — | $22.30M | 0.0% | n/c | 1 | SEC ↗ |
| 41 | UBS Group AG | 680.57K | — | $22.30M | 0.0% | n/c | 1 | SEC ↗ |
| 42 | Point72 Asset Management ✦ | 662.35K | Nuovo | $21.70M | 0.0% | New | 1 | SEC ↗ |
| 43 | Charles Schwab Investment… | 574.62K | — | $18.82M | 0.0% | n/c | 1 | SEC ↗ |
| 44 | Northern Trust Corp | 561.02K | — | $18.38M | 0.0% | n/c | 1 | SEC ↗ |
| 45 | Northern Trust Corp | 561.02K | — | $18.38M | 0.0% | n/c | 1 | SEC ↗ |
| 46 | Northern Trust Corp | 561.02K | — | $18.38M | 0.0% | n/c | 1 | SEC ↗ |
| 47 | Northern Trust Corp | 561.02K | — | $18.38M | 0.0% | n/c | 1 | SEC ↗ |
| 48 | Northern Trust Corp | 561.02K | — | $18.38M | 0.0% | n/c | 1 | SEC ↗ |
| 49 | Northern Trust Corp | 561.02K | — | $18.38M | 0.0% | n/c | 1 | SEC ↗ |
| 50 | Bank Of America Corp /De/ | 419.73K | — | $13.75M | 0.0% | n/c | 1 | SEC ↗ |
| 51 | Bank Of America Corp /De/ | 419.73K | — | $13.75M | 0.0% | n/c | 1 | SEC ↗ |
| 52 | Bank Of America Corp /De/ | 419.73K | — | $13.75M | 0.0% | n/c | 1 | SEC ↗ |
| 53 | Goldman Sachs Group ✦ | 275.06K | -16.5% | $9.01M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 54 | Goldman Sachs Group ✦ | 275.06K | -16.5% | $9.01M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 55 | Capital World Investors ✦ | 200.17K | 0.0% | $6.56M | 0.0% | Held | 5 | SEC ↗ |
| 56 | Bank of New York Mellon Corp | 192.83K | — | $6.32M | 0.0% | n/c | 1 | SEC ↗ |
| 57 | Bank of New York Mellon Corp | 192.83K | — | $6.32M | 0.0% | n/c | 1 | SEC ↗ |
| 58 | Bank of New York Mellon Corp | 192.83K | — | $6.32M | 0.0% | n/c | 1 | SEC ↗ |
| 59 | Bank of New York Mellon Corp | 192.83K | — | $6.32M | 0.0% | n/c | 1 | SEC ↗ |
| 60 | Morgan Stanley ✦ | 182.73K | -45.4% | $5.99M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 61 | Morgan Stanley ✦ | 182.73K | -45.4% | $5.99M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 62 | Morgan Stanley ✦ | 182.73K | -45.4% | $5.99M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 63 | Morgan Stanley ✦ | 182.73K | -45.4% | $5.99M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 64 | Morgan Stanley ✦ | 182.73K | -45.4% | $5.99M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 65 | Morgan Stanley ✦ | 182.73K | -45.4% | $5.99M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 66 | Barclays Plc | 182.52K | — | $5.98M | 0.0% | n/c | 1 | SEC ↗ |
| 67 | Barclays Plc | 182.52K | — | $5.98M | 0.0% | n/c | 1 | SEC ↗ |
| 68 | Universal- Beteiligungs- und… | 171.21K | — | $5.61M | 0.0% | n/c | 1 | SEC ↗ |
| 69 | Nuveen, LLC | 150.98K | — | $4.95M | 0.0% | n/c | 1 | SEC ↗ |
| 70 | Nuveen, LLC | 150.98K | — | $4.95M | 0.0% | n/c | 1 | SEC ↗ |
| 71 | Invesco Ltd. | 150.93K | — | $4.94M | 0.0% | n/c | 1 | SEC ↗ |
| 72 | Invesco Ltd. | 150.93K | — | $4.94M | 0.0% | n/c | 1 | SEC ↗ |
| 73 | Invesco Ltd. | 150.93K | — | $4.94M | 0.0% | n/c | 1 | SEC ↗ |
| 74 | Invesco Ltd. | 150.93K | — | $4.94M | 0.0% | n/c | 1 | SEC ↗ |
| 75 | Td Asset Management Inc | 149.82K | — | $4.91M | 0.0% | n/c | 1 | SEC ↗ |
| 76 | Victory Capital Management Inc | 146.08K | — | $4.79M | 0.0% | n/c | 1 | SEC ↗ |
| 77 | Manufacturers Life Insurance… | 129.01K | — | $4.14M | 0.0% | n/c | 1 | SEC ↗ |
| 78 | Deutsche Bank Ag\ | 121.94K | — | $3.99M | 0.0% | n/c | 1 | SEC ↗ |
| 79 | Deutsche Bank Ag\ | 121.94K | — | $3.99M | 0.0% | n/c | 1 | SEC ↗ |
| 80 | Deutsche Bank Ag\ | 121.94K | — | $3.99M | 0.0% | n/c | 1 | SEC ↗ |
| 81 | Mercer Global Advisors Inc /Adv | 106.32K | — | $3.48M | 0.0% | n/c | 1 | SEC ↗ |
| 82 | Citigroup Inc | 100.06K | — | $3.28M | 0.0% | n/c | 1 | SEC ↗ |
| 83 | Citigroup Inc | 100.06K | — | $3.28M | 0.0% | n/c | 1 | SEC ↗ |
| 84 | Swiss National Bank | 96.50K | — | $3.16M | 0.0% | n/c | 1 | SEC ↗ |
| 85 | Rhumbline Advisers | 82.96K | — | $2.72M | 0.0% | n/c | 1 | SEC ↗ |
| 86 | Wells Fargo & Company/Mn | 82.42K | — | $2.70M | 0.0% | n/c | 1 | SEC ↗ |
| 87 | Wells Fargo & Company/Mn | 82.42K | — | $2.70M | 0.0% | n/c | 1 | SEC ↗ |
| 88 | Dimensional Fund Advisors Lp | 77.29K | — | $2.53M | 0.0% | n/c | 1 | SEC ↗ |
| 89 | Millennium Management ✦ | 76.19K | -81.3% | $2.50M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 90 | Balyasny Asset Management L.P. | 73.47K | — | $2.41M | 0.0% | n/c | 1 | SEC ↗ |
| 91 | Alliancebernstein L.P. | 67.50K | — | $2.21M | 0.0% | n/c | 1 | SEC ↗ |
| 92 | Citadel Advisors ✦ | 63.90K | Nuovo | $2.09M | 0.0% | New | 1 | SEC ↗ |
| 93 | JPMorgan Chase ✦ | 62.95K | -88.6% | $2.06M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 94 | JPMorgan Chase ✦ | 62.95K | -88.6% | $2.06M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 95 | JPMorgan Chase ✦ | 62.95K | -88.6% | $2.06M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 96 | JPMorgan Chase ✦ | 62.95K | -88.6% | $2.06M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 97 | UBS AM, a distinct business unit of… | 62.22K | — | $2.04M | 0.0% | n/c | 1 | SEC ↗ |
| 98 | UBS AM, a distinct business unit of… | 62.22K | — | $2.04M | 0.0% | n/c | 1 | SEC ↗ |
| 99 | UBS AM, a distinct business unit of… | 62.22K | — | $2.04M | 0.0% | n/c | 1 | SEC ↗ |
| 100 | Legal & General Group Plc | 56.45K | — | $1.85M | 0.0% | n/c | 1 | SEC ↗ |
"Il loro peso" = la quota della posizione sul valore azionario 13F dichiarato da quel gestore — la misura di convinzione. ✦ = gestore selezionato.
Nuovi acquirenti
| Point72 Asset Management | $21.70M | 0.0% |
| Citadel Advisors | $2.09M | 0.0% |
Uscito
| Nessuna uscita tracciata questo trimestre. |
Contesto di mercato completo: su TUTTI i filer 13F (dati strutturati SEC, Q1 2026): 197 detentori, 82.12M azioni, $4.06B dichiarato. Questo è un periodo diverso e più vecchio rispetto ai dati dell'universo monitorato riportati sopra e i due non vengono mai combinati.
Frequentemente co-detenuti
Cosa detengono più spesso gli altri holder monitorati di questo titolo — conteggi di proprietà condivisa, non relazioni fondamentali.
Acquisti sul mercato aperto (P)
Nessun acquisto insider sul mercato aperto nella nostra finestra di copertura.
Vendite sul mercato aperto (S)
Aug 07
Albers Jeffrey W.
Director · 5.00K az. · $522,350
Aug 07
Albers Jeffrey W.
Director · 8.00K az. · $835,040
Aug 07
Albers Jeffrey W.
Director · 10.00K az. · $1.05M
Assegnazioni, esercizi e ritenute fiscali non vengono mai conteggiati come acquisti o vendite in questa sede. Metodologia
Aug 14
SC 13G/A — RTW INVESTMENTS, LP
Aug 14
SC 13G/A — PERCEPTIVE ADVISORS LLC
Jun 23
SC 13D/A — Fairmount Funds Management LLC
9.2% di classe · Visualizza la dichiarazione SEC originale ↗
Provenienza: Proprietà ricavata dalle posizioni in azioni ordinarie 13F analizzate (universo monitorato, set comparabili per le variazioni); righe insider dai Moduli 3/4/5; partecipazioni dagli Schedule 13D/13G; ogni filing rimanda all'originale su SEC EDGAR.
Periodo di rendicontazione: Q4 2025 ·
Metodologia ·
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