Ficha del valor · trimestre archivado
SYRE
Spyre Therapeutics, Inc. · Healthcare · Biotechnology
69Tenedores rastreados
+2Δ titulares
41.90MAcciones mantenidas
$1.37BValor declarado
+2Nuevas posiciones
−0Cierres
Señales de momentum (gestores comparables):
amplitud de titulares +3.0% ·
flujo de acciones +18.7% ·
nuevas posiciones netas +2.9%
— fórmula
Acumulación amplia — aumento de acciones entre más titulares
Todas las cifras de propiedad: únicamente gestores 13F seguidos, posiciones en acciones ordinarias, período de referencia Q4 2025
Participación a lo largo del tiempo
| Trimestre | Titulares | Δ | Acciones | Valor declarado | Nuevo | Cierres |
|---|---|---|---|---|---|---|
| Q2 2026 | 99 | +22 | 55.43M | $4.93B | +25 | −3 |
| Q1 2026 | 80 | +10 | 41.69M | $2.10B | +12 | −2 |
| Q4 2025 | 69 | +2 | 41.90M | $1.37B | +2 | — |
| Q3 2025 | 13 | -1 | 23.21M | $388.94M | +1 | −2 |
| Q2 2025 | 11 | 0 | 22.40M | $335.38M | +2 | −2 |
| Q1 2025 | 8 | -2 | 6.01M | $96.96M | — | −2 |
| Q4 2024 | 10 | +1 | 7.67M | $178.64M | +2 | −1 |
| Q3 2024 | 8 | 0 | 4.78M | $140.58M | +1 | −1 |
| Q2 2024 | 8 | — | 3.96M | $93.00M | — | — |
Quién lo tiene en cartera · Q4 2025
| # | Gestor | Acciones | Δ acciones | Valor | Su ponderación | Mantenida | ||
|---|---|---|---|---|---|---|---|---|
| 1 | Fidelity (FMR) ✦ | 11.64M | +28.5% | $381.29M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 2 | Fidelity (FMR) ✦ | 11.64M | +28.5% | $381.29M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 3 | Fidelity (FMR) ✦ | 11.64M | +28.5% | $381.29M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 4 | BlackRock ✦ (pasivo) | 5.52M | +38.6% | $180.90M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 5 | BlackRock ✦ (pasivo) | 5.52M | +38.6% | $180.90M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 6 | BlackRock ✦ (pasivo) | 5.52M | +38.6% | $180.90M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 7 | BlackRock ✦ (pasivo) | 5.52M | +38.6% | $180.90M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 8 | BlackRock ✦ (pasivo) | 5.52M | +38.6% | $180.90M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 9 | BlackRock ✦ (pasivo) | 5.52M | +38.6% | $180.90M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 10 | BlackRock ✦ (pasivo) | 5.52M | +38.6% | $180.90M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 11 | BlackRock ✦ (pasivo) | 5.52M | +38.6% | $180.90M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 12 | BlackRock ✦ (pasivo) | 5.52M | +38.6% | $180.90M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 13 | BlackRock ✦ (pasivo) | 5.52M | +38.6% | $180.90M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 14 | BlackRock ✦ (pasivo) | 5.52M | +38.6% | $180.90M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 15 | BlackRock ✦ (pasivo) | 5.52M | +38.6% | $180.90M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 16 | The Vanguard Group ✦ (pasivo) | 4.04M | +32.3% | $132.19M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 17 | The Vanguard Group ✦ (pasivo) | 4.04M | +32.3% | $132.19M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 18 | The Vanguard Group ✦ (pasivo) | 4.04M | +32.3% | $132.19M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 19 | The Vanguard Group ✦ (pasivo) | 4.04M | +32.3% | $132.19M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 20 | The Vanguard Group ✦ (pasivo) | 4.04M | +32.3% | $132.19M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 21 | Capital International Investors | 3.49M | — | $114.42M | 0.0% | n/c | 1 | SEC ↗ |
| 22 | State Street Global Advisors ✦ (pasivo) | 2.26M | +26.8% | $74.13M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 23 | Janus Henderson Group Plc | 1.83M | — | $59.92M | 0.0% | n/c | 1 | SEC ↗ |
| 24 | Janus Henderson Group Plc | 1.83M | — | $59.92M | 0.0% | n/c | 1 | SEC ↗ |
| 25 | Geode Capital Management ✦ (pasivo) | 1.66M | +35.4% | $54.36M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 26 | Geode Capital Management ✦ (pasivo) | 1.66M | +35.4% | $54.36M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 27 | T. Rowe Price ✦ | 1.60M | +158.1% | $52.48M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 28 | T. Rowe Price ✦ | 1.60M | +158.1% | $52.48M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 29 | Wellington Management ✦ | 1.55M | -5.5% | $50.75M | 0.0% | ▼ Trim | 7 | SEC ↗ |
| 30 | Wellington Management ✦ | 1.55M | -5.5% | $50.75M | 0.0% | ▼ Trim | 7 | SEC ↗ |
| 31 | Wellington Management ✦ | 1.55M | -5.5% | $50.75M | 0.0% | ▼ Trim | 7 | SEC ↗ |
| 32 | Wellington Management ✦ | 1.55M | -5.5% | $50.75M | 0.0% | ▼ Trim | 7 | SEC ↗ |
| 33 | Wellington Management ✦ | 1.55M | -5.5% | $50.75M | 0.0% | ▼ Trim | 7 | SEC ↗ |
| 34 | Wellington Management ✦ | 1.55M | -5.5% | $50.75M | 0.0% | ▼ Trim | 7 | SEC ↗ |
| 35 | Wellington Management ✦ | 1.55M | -5.5% | $50.75M | 0.0% | ▼ Trim | 7 | SEC ↗ |
| 36 | Franklin Resources Inc | 1.11M | — | $36.34M | 0.0% | n/c | 1 | SEC ↗ |
| 37 | Franklin Resources Inc | 1.11M | — | $36.34M | 0.0% | n/c | 1 | SEC ↗ |
| 38 | Pictet Asset Management Holding SA | 913.96K | — | $29.94M | 0.0% | n/c | 1 | SEC ↗ |
| 39 | UBS Group AG | 680.57K | — | $22.30M | 0.0% | n/c | 1 | SEC ↗ |
| 40 | UBS Group AG | 680.57K | — | $22.30M | 0.0% | n/c | 1 | SEC ↗ |
| 41 | UBS Group AG | 680.57K | — | $22.30M | 0.0% | n/c | 1 | SEC ↗ |
| 42 | Point72 Asset Management ✦ | 662.35K | Nuevo | $21.70M | 0.0% | New | 1 | SEC ↗ |
| 43 | Charles Schwab Investment… | 574.62K | — | $18.82M | 0.0% | n/c | 1 | SEC ↗ |
| 44 | Northern Trust Corp | 561.02K | — | $18.38M | 0.0% | n/c | 1 | SEC ↗ |
| 45 | Northern Trust Corp | 561.02K | — | $18.38M | 0.0% | n/c | 1 | SEC ↗ |
| 46 | Northern Trust Corp | 561.02K | — | $18.38M | 0.0% | n/c | 1 | SEC ↗ |
| 47 | Northern Trust Corp | 561.02K | — | $18.38M | 0.0% | n/c | 1 | SEC ↗ |
| 48 | Northern Trust Corp | 561.02K | — | $18.38M | 0.0% | n/c | 1 | SEC ↗ |
| 49 | Northern Trust Corp | 561.02K | — | $18.38M | 0.0% | n/c | 1 | SEC ↗ |
| 50 | Bank Of America Corp /De/ | 419.73K | — | $13.75M | 0.0% | n/c | 1 | SEC ↗ |
| 51 | Bank Of America Corp /De/ | 419.73K | — | $13.75M | 0.0% | n/c | 1 | SEC ↗ |
| 52 | Bank Of America Corp /De/ | 419.73K | — | $13.75M | 0.0% | n/c | 1 | SEC ↗ |
| 53 | Goldman Sachs Group ✦ | 275.06K | -16.5% | $9.01M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 54 | Goldman Sachs Group ✦ | 275.06K | -16.5% | $9.01M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 55 | Capital World Investors ✦ | 200.17K | 0.0% | $6.56M | 0.0% | Held | 5 | SEC ↗ |
| 56 | Bank of New York Mellon Corp | 192.83K | — | $6.32M | 0.0% | n/c | 1 | SEC ↗ |
| 57 | Bank of New York Mellon Corp | 192.83K | — | $6.32M | 0.0% | n/c | 1 | SEC ↗ |
| 58 | Bank of New York Mellon Corp | 192.83K | — | $6.32M | 0.0% | n/c | 1 | SEC ↗ |
| 59 | Bank of New York Mellon Corp | 192.83K | — | $6.32M | 0.0% | n/c | 1 | SEC ↗ |
| 60 | Morgan Stanley ✦ | 182.73K | -45.4% | $5.99M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 61 | Morgan Stanley ✦ | 182.73K | -45.4% | $5.99M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 62 | Morgan Stanley ✦ | 182.73K | -45.4% | $5.99M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 63 | Morgan Stanley ✦ | 182.73K | -45.4% | $5.99M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 64 | Morgan Stanley ✦ | 182.73K | -45.4% | $5.99M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 65 | Morgan Stanley ✦ | 182.73K | -45.4% | $5.99M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 66 | Barclays Plc | 182.52K | — | $5.98M | 0.0% | n/c | 1 | SEC ↗ |
| 67 | Barclays Plc | 182.52K | — | $5.98M | 0.0% | n/c | 1 | SEC ↗ |
| 68 | Universal- Beteiligungs- und… | 171.21K | — | $5.61M | 0.0% | n/c | 1 | SEC ↗ |
| 69 | Nuveen, LLC | 150.98K | — | $4.95M | 0.0% | n/c | 1 | SEC ↗ |
| 70 | Nuveen, LLC | 150.98K | — | $4.95M | 0.0% | n/c | 1 | SEC ↗ |
| 71 | Invesco Ltd. | 150.93K | — | $4.94M | 0.0% | n/c | 1 | SEC ↗ |
| 72 | Invesco Ltd. | 150.93K | — | $4.94M | 0.0% | n/c | 1 | SEC ↗ |
| 73 | Invesco Ltd. | 150.93K | — | $4.94M | 0.0% | n/c | 1 | SEC ↗ |
| 74 | Invesco Ltd. | 150.93K | — | $4.94M | 0.0% | n/c | 1 | SEC ↗ |
| 75 | Td Asset Management Inc | 149.82K | — | $4.91M | 0.0% | n/c | 1 | SEC ↗ |
| 76 | Victory Capital Management Inc | 146.08K | — | $4.79M | 0.0% | n/c | 1 | SEC ↗ |
| 77 | Manufacturers Life Insurance… | 129.01K | — | $4.14M | 0.0% | n/c | 1 | SEC ↗ |
| 78 | Deutsche Bank Ag\ | 121.94K | — | $3.99M | 0.0% | n/c | 1 | SEC ↗ |
| 79 | Deutsche Bank Ag\ | 121.94K | — | $3.99M | 0.0% | n/c | 1 | SEC ↗ |
| 80 | Deutsche Bank Ag\ | 121.94K | — | $3.99M | 0.0% | n/c | 1 | SEC ↗ |
| 81 | Mercer Global Advisors Inc /Adv | 106.32K | — | $3.48M | 0.0% | n/c | 1 | SEC ↗ |
| 82 | Citigroup Inc | 100.06K | — | $3.28M | 0.0% | n/c | 1 | SEC ↗ |
| 83 | Citigroup Inc | 100.06K | — | $3.28M | 0.0% | n/c | 1 | SEC ↗ |
| 84 | Swiss National Bank | 96.50K | — | $3.16M | 0.0% | n/c | 1 | SEC ↗ |
| 85 | Rhumbline Advisers | 82.96K | — | $2.72M | 0.0% | n/c | 1 | SEC ↗ |
| 86 | Wells Fargo & Company/Mn | 82.42K | — | $2.70M | 0.0% | n/c | 1 | SEC ↗ |
| 87 | Wells Fargo & Company/Mn | 82.42K | — | $2.70M | 0.0% | n/c | 1 | SEC ↗ |
| 88 | Dimensional Fund Advisors Lp | 77.29K | — | $2.53M | 0.0% | n/c | 1 | SEC ↗ |
| 89 | Millennium Management ✦ | 76.19K | -81.3% | $2.50M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 90 | Balyasny Asset Management L.P. | 73.47K | — | $2.41M | 0.0% | n/c | 1 | SEC ↗ |
| 91 | Alliancebernstein L.P. | 67.50K | — | $2.21M | 0.0% | n/c | 1 | SEC ↗ |
| 92 | Citadel Advisors ✦ | 63.90K | Nuevo | $2.09M | 0.0% | New | 1 | SEC ↗ |
| 93 | JPMorgan Chase ✦ | 62.95K | -88.6% | $2.06M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 94 | JPMorgan Chase ✦ | 62.95K | -88.6% | $2.06M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 95 | JPMorgan Chase ✦ | 62.95K | -88.6% | $2.06M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 96 | JPMorgan Chase ✦ | 62.95K | -88.6% | $2.06M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 97 | UBS AM, a distinct business unit of… | 62.22K | — | $2.04M | 0.0% | n/c | 1 | SEC ↗ |
| 98 | UBS AM, a distinct business unit of… | 62.22K | — | $2.04M | 0.0% | n/c | 1 | SEC ↗ |
| 99 | UBS AM, a distinct business unit of… | 62.22K | — | $2.04M | 0.0% | n/c | 1 | SEC ↗ |
| 100 | Legal & General Group Plc | 56.45K | — | $1.85M | 0.0% | n/c | 1 | SEC ↗ |
«Su ponderación» = la participación de la posición en el valor de renta variable 13F declarado por ese gestor — la medida de convicción. ✦ = gestor seleccionado.
Nuevos compradores
| Point72 Asset Management | $21.70M | 0.0% |
| Citadel Advisors | $2.09M | 0.0% |
Posición cerrada
| Sin salidas rastreadas este trimestre. |
Contexto de mercado completo: entre TODOS los filers 13F (datos estructurados SEC, Q1 2026): 197 tenedores, 82.12M acciones, $4.06B declarado. Este es un período diferente y anterior al de las cifras del universo rastreado que figuran arriba, y ambos nunca se mezclan.
Frecuentemente cotituladas
Qué otros valores suelen tener también los tenedores rastreados de este activo — recuentos de cotenencia, no relaciones fundamentales.
Compras en mercado abierto (P)
Sin compras en mercado abierto por parte de insiders en nuestra ventana de cobertura.
Ventas en mercado abierto (S)
Aug 07
Albers Jeffrey W.
Director · 5.00K acc. · $522,350
Aug 07
Albers Jeffrey W.
Director · 8.00K acc. · $835,040
Aug 07
Albers Jeffrey W.
Director · 10.00K acc. · $1.05M
Las adjudicaciones, ejercicios y retenciones fiscales nunca se contabilizan aquí como compras o ventas. Metodología
Aug 14
SC 13G/A — RTW INVESTMENTS, LP
Aug 14
SC 13G/A — PERCEPTIVE ADVISORS LLC
Jun 23
SC 13D/A — Fairmount Funds Management LLC
9.2% de clase · Ver presentación original ante la SEC ↗
Procedencia: Participación a partir de posiciones en acciones ordinarias de 13F procesadas (universo rastreado, conjuntos comparables para cambios); filas de iniciados de los Formularios 3/4/5; participaciones de los Schedules 13D/13G; cada filing enlaza con su original en SEC EDGAR.
Período de reporte: Q4 2025 ·
Metodología ·
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