Security record · archived quarter
RYTM
Rhythm Pharmaceuticals, Inc. · Healthcare · Biotechnology
102Tracked holders
0Δ holders
43.14MShares held
$4.62BReported value
+3New positions
−2Exits
Momentum inputs (comparable managers): holder breadth 0.0% · share flow +0.1% · net new positions +1.0% — formula
All ownership figures: tracked 13F managers only, common-stock positions, reporting period Q4 2025
Ownership over time
| Quarter | Holders | Δ | Shares | Reported value | New | Exits |
|---|---|---|---|---|---|---|
| Q2 2026 | 113 | +6 | 44.38M | $4.90B | +14 | −7 |
| Q1 2026 | 109 | +6 | 41.83M | $3.64B | +11 | −6 |
| Q4 2025 | 102 | 0 | 43.14M | $4.62B | +3 | −2 |
| Q3 2025 | 20 | +1 | 28.88M | $2.92B | +2 | −2 |
| Q2 2025 | 17 | 0 | 22.96M | $1.45B | +1 | −1 |
| Q1 2025 | 14 | +2 | 11.52M | $610.22M | +2 | — |
| Q4 2024 | 12 | 0 | 11.40M | $638.39M | — | — |
| Q3 2024 | 11 | +3 | 9.71M | $508.75M | +3 | — |
| Q2 2024 | 8 | — | 9.56M | $392.54M | — | — |
Who holds it · Q4 2025
| # | Manager | Shares | Δ shares | Value | Their weight | Held | ||
|---|---|---|---|---|---|---|---|---|
| 1 | BlackRock ✦ (passive) | 6.30M | -0.1% | $674.07M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 2 | BlackRock ✦ (passive) | 6.30M | -0.1% | $674.07M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 3 | BlackRock ✦ (passive) | 6.30M | -0.1% | $674.07M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 4 | BlackRock ✦ (passive) | 6.30M | -0.1% | $674.07M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 5 | BlackRock ✦ (passive) | 6.30M | -0.1% | $674.07M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 6 | BlackRock ✦ (passive) | 6.30M | -0.1% | $674.07M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 7 | BlackRock ✦ (passive) | 6.30M | -0.1% | $674.07M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 8 | BlackRock ✦ (passive) | 6.30M | -0.1% | $674.07M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 9 | BlackRock ✦ (passive) | 6.30M | -0.1% | $674.07M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 10 | BlackRock ✦ (passive) | 6.30M | -0.1% | $674.07M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 11 | BlackRock ✦ (passive) | 6.30M | -0.1% | $674.07M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 12 | BlackRock ✦ (passive) | 6.30M | -0.1% | $674.07M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 13 | BlackRock ✦ (passive) | 6.30M | -0.1% | $674.07M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 14 | BlackRock ✦ (passive) | 6.30M | -0.1% | $674.07M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 15 | BlackRock ✦ (passive) | 6.30M | -0.1% | $674.07M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 16 | BlackRock ✦ (passive) | 6.30M | -0.1% | $674.07M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 17 | BlackRock ✦ (passive) | 6.30M | -0.1% | $674.07M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 18 | The Vanguard Group ✦ (passive) | 6.21M | +24.3% | $664.82M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 19 | The Vanguard Group ✦ (passive) | 6.21M | +24.3% | $664.82M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 20 | The Vanguard Group ✦ (passive) | 6.21M | +24.3% | $664.82M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 21 | The Vanguard Group ✦ (passive) | 6.21M | +24.3% | $664.82M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 22 | The Vanguard Group ✦ (passive) | 6.21M | +24.3% | $664.82M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 23 | PRIMECAP Management ✦ | 3.48M | -18.4% | $372.36M | 0.3% | ▼ Trim | 7 | SEC ↗ |
| 24 | State Street Global Advisors ✦ (passive) | 2.20M | +8.4% | $235.34M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 25 | Goldman Sachs Group ✦ | 1.83M | -3.3% | $195.98M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 26 | Goldman Sachs Group ✦ | 1.83M | -3.3% | $195.98M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 27 | Goldman Sachs Group ✦ | 1.83M | -3.3% | $195.98M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 28 | Fidelity (FMR) ✦ | 1.71M | -20.5% | $182.64M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 29 | Fidelity (FMR) ✦ | 1.71M | -20.5% | $182.64M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 30 | Fidelity (FMR) ✦ | 1.71M | -20.5% | $182.64M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 31 | Fidelity (FMR) ✦ | 1.71M | -20.5% | $182.64M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 32 | Federated Hermes, Inc. | 1.62M | — | $173.82M | 0.3% | n/c | 1 | SEC ↗ |
| 33 | Federated Hermes, Inc. | 1.62M | — | $173.82M | 0.3% | n/c | 1 | SEC ↗ |
| 34 | Federated Hermes, Inc. | 1.62M | — | $173.82M | 0.3% | n/c | 1 | SEC ↗ |
| 35 | T. Rowe Price ✦ | 1.56M | +11.5% | $167.07M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 36 | T. Rowe Price ✦ | 1.56M | +11.5% | $167.07M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 37 | JPMorgan Chase ✦ | 1.42M | -40.1% | $152.42M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 38 | JPMorgan Chase ✦ | 1.42M | -40.1% | $152.42M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 39 | JPMorgan Chase ✦ | 1.42M | -40.1% | $152.42M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 40 | JPMorgan Chase ✦ | 1.42M | -40.1% | $152.42M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 41 | JPMorgan Chase ✦ | 1.42M | -40.1% | $152.42M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 42 | Geode Capital Management ✦ (passive) | 1.38M | +0.9% | $147.28M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 43 | Geode Capital Management ✦ (passive) | 1.38M | +0.9% | $147.28M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 44 | Janus Henderson Group Plc | 1.13M | — | $120.59M | 0.1% | n/c | 1 | SEC ↗ |
| 45 | Janus Henderson Group Plc | 1.13M | — | $120.59M | 0.1% | n/c | 1 | SEC ↗ |
| 46 | Capital Research Global Investors | 985.09K | — | $105.44M | 0.0% | n/c | 1 | SEC ↗ |
| 47 | Alliancebernstein L.P. | 930.23K | — | $99.57M | 0.0% | n/c | 1 | SEC ↗ |
| 48 | Jennison Associates Llc | 918.57K | — | $98.32M | 0.1% | n/c | 1 | SEC ↗ |
| 49 | Jennison Associates Llc | 918.57K | — | $98.32M | 0.1% | n/c | 1 | SEC ↗ |
| 50 | Franklin Resources Inc | 695.74K | — | $74.47M | 0.0% | n/c | 1 | SEC ↗ |
| 51 | Franklin Resources Inc | 695.74K | — | $74.47M | 0.0% | n/c | 1 | SEC ↗ |
| 52 | Franklin Resources Inc | 695.74K | — | $74.47M | 0.0% | n/c | 1 | SEC ↗ |
| 53 | Franklin Resources Inc | 695.74K | — | $74.47M | 0.0% | n/c | 1 | SEC ↗ |
| 54 | Franklin Resources Inc | 695.74K | — | $74.47M | 0.0% | n/c | 1 | SEC ↗ |
| 55 | Franklin Resources Inc | 695.74K | — | $74.47M | 0.0% | n/c | 1 | SEC ↗ |
| 56 | Morgan Stanley ✦ | 651.40K | +40.0% | $69.73M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 57 | Morgan Stanley ✦ | 651.40K | +40.0% | $69.73M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 58 | Morgan Stanley ✦ | 651.40K | +40.0% | $69.73M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 59 | Morgan Stanley ✦ | 651.40K | +40.0% | $69.73M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 60 | Morgan Stanley ✦ | 651.40K | +40.0% | $69.73M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 61 | Morgan Stanley ✦ | 651.40K | +40.0% | $69.73M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 62 | Morgan Stanley ✦ | 651.40K | +40.0% | $69.73M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 63 | Adage Capital Partners ✦ | 621.59K | +14.3% | $66.53M | 0.1% | ▲ Add | 3 | SEC ↗ |
| 64 | Pictet Asset Management Holding SA | 614.66K | — | $66.19M | 0.1% | n/c | 1 | SEC ↗ |
| 65 | UBS AM, a distinct business unit of… | 549.02K | — | $58.77M | 0.0% | n/c | 1 | SEC ↗ |
| 66 | UBS AM, a distinct business unit of… | 549.02K | — | $58.77M | 0.0% | n/c | 1 | SEC ↗ |
| 67 | UBS AM, a distinct business unit of… | 549.02K | — | $58.77M | 0.0% | n/c | 1 | SEC ↗ |
| 68 | UBS AM, a distinct business unit of… | 549.02K | — | $58.77M | 0.0% | n/c | 1 | SEC ↗ |
| 69 | UBS AM, a distinct business unit of… | 549.02K | — | $58.77M | 0.0% | n/c | 1 | SEC ↗ |
| 70 | UBS AM, a distinct business unit of… | 549.02K | — | $58.77M | 0.0% | n/c | 1 | SEC ↗ |
| 71 | UBS AM, a distinct business unit of… | 549.02K | — | $58.77M | 0.0% | n/c | 1 | SEC ↗ |
| 72 | UBS AM, a distinct business unit of… | 549.02K | — | $58.77M | 0.0% | n/c | 1 | SEC ↗ |
| 73 | Charles Schwab Investment… | 532.45K | — | $56.99M | 0.0% | n/c | 1 | SEC ↗ |
| 74 | Clearbridge Investments, LLC | 506.11K | — | $54.17M | 0.0% | n/c | 1 | SEC ↗ |
| 75 | Loomis Sayles & Co L P | 503.90K | — | $53.94M | 0.1% | n/c | 1 | SEC ↗ |
| 76 | Loomis Sayles & Co L P | 503.90K | — | $53.94M | 0.1% | n/c | 1 | SEC ↗ |
| 77 | Northern Trust Corp | 488.22K | — | $52.26M | 0.0% | n/c | 1 | SEC ↗ |
| 78 | Northern Trust Corp | 488.22K | — | $52.26M | 0.0% | n/c | 1 | SEC ↗ |
| 79 | Northern Trust Corp | 488.22K | — | $52.26M | 0.0% | n/c | 1 | SEC ↗ |
| 80 | Northern Trust Corp | 488.22K | — | $52.26M | 0.0% | n/c | 1 | SEC ↗ |
| 81 | Northern Trust Corp | 488.22K | — | $52.26M | 0.0% | n/c | 1 | SEC ↗ |
| 82 | Northern Trust Corp | 488.22K | — | $52.26M | 0.0% | n/c | 1 | SEC ↗ |
| 83 | Point72 Asset Management ✦ | 429.42K | New | $45.97M | 0.1% | New | 1 | SEC ↗ |
| 84 | UBS Group AG | 427.24K | — | $45.73M | 0.0% | n/c | 1 | SEC ↗ |
| 85 | UBS Group AG | 427.24K | — | $45.73M | 0.0% | n/c | 1 | SEC ↗ |
| 86 | UBS Group AG | 427.24K | — | $45.73M | 0.0% | n/c | 1 | SEC ↗ |
| 87 | UBS Group AG | 427.24K | — | $45.73M | 0.0% | n/c | 1 | SEC ↗ |
| 88 | Renaissance Technologies ✦ | 341.19K | -37.6% | $36.52M | 0.1% | ▼ Trim | 4 | SEC ↗ |
| 89 | Qube Research & Technologies Ltd | 310.92K | — | $33.28M | 0.0% | n/c | 1 | SEC ↗ |
| 90 | Bank of New York Mellon Corp | 301.08K | — | $32.23M | 0.0% | n/c | 1 | SEC ↗ |
| 91 | Bank of New York Mellon Corp | 301.08K | — | $32.23M | 0.0% | n/c | 1 | SEC ↗ |
| 92 | Bank of New York Mellon Corp | 301.08K | — | $32.23M | 0.0% | n/c | 1 | SEC ↗ |
| 93 | Bank of New York Mellon Corp | 301.08K | — | $32.23M | 0.0% | n/c | 1 | SEC ↗ |
| 94 | Bank of New York Mellon Corp | 301.08K | — | $32.23M | 0.0% | n/c | 1 | SEC ↗ |
| 95 | Bank of New York Mellon Corp | 301.08K | — | $32.23M | 0.0% | n/c | 1 | SEC ↗ |
| 96 | Bank of New York Mellon Corp | 301.08K | — | $32.23M | 0.0% | n/c | 1 | SEC ↗ |
| 97 | Bank of New York Mellon Corp | 301.08K | — | $32.23M | 0.0% | n/c | 1 | SEC ↗ |
| 98 | Bank of New York Mellon Corp | 301.08K | — | $32.23M | 0.0% | n/c | 1 | SEC ↗ |
| 99 | Bank of New York Mellon Corp | 301.08K | — | $32.23M | 0.0% | n/c | 1 | SEC ↗ |
| 100 | Bank of New York Mellon Corp | 301.08K | — | $32.23M | 0.0% | n/c | 1 | SEC ↗ |
“Their weight” = the position's share of that manager's reported 13F equity value — the conviction measure. ✦ = curated manager.
New buyers
| Point72 Asset Management | $45.97M | 0.1% |
Exited
| Marshall Wace | $17.35M | was 0.0% |
| Arrowstreet Capital | $636,944 | was 0.0% |
Full-market context: across ALL 13F filers (SEC structured data, Q1 2026): 284 holders, 72.02M shares, $6.12B reported. This is a different, older period than the tracked-universe figures above and the two are never mixed.
Frequently co-owned
What else this security's tracked holders most often hold — shared-ownership counts, not fundamental relationships.
Open-market purchases (P)
No open-market insider purchases in our coverage window.
Open-market sales (S)
Aug 13
Garfield Alastair
Officer · 2.01K sh · $233,031
Aug 13
Garfield Alastair
Officer · 1.56K sh · $182,170
Aug 13
Garfield Alastair
Officer · 3.40K sh · $402,167
Aug 13
Garfield Alastair
Officer · 800 sh · $95,335
Aug 13
Lee Jennifer Kayden
Officer · 75.83K sh · $8.90M
Aug 12
Mazabraud Yann
Officer · 2.30K sh · $257,138
Aug 12
Mazabraud Yann
Officer · 1.00K sh · $112,856
Aug 12
Mazabraud Yann
Officer · 3.60K sh · $413,477
Aug 12
Mazabraud Yann
Officer · 14.57K sh · $1.68M
Aug 12
Mazabraud Yann
Officer · 18.21K sh · $2.12M
Awards, exercises and tax withholding are never counted as buys or sales here. Methodology
Provenance: Ownership from parsed 13F common-stock positions (tracked universe, comparable sets for changes); insider rows from Forms 3/4/5; stakes from Schedules 13D/13G; every filing links to its original on SEC EDGAR.
Reporting period: Q4 2025 ·
Methodology ·
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