Security record · archived quarter
RYTM
Rhythm Pharmaceuticals, Inc. · Healthcare · Biotechnology
102Tracked holders
0Δ holders
43.14MShares held
$4.62BReported value
+3New positions
−2Exits
Momentum inputs (comparable managers): holder breadth 0.0% · share flow +0.1% · net new positions +1.0% — formula
All ownership figures: tracked 13F managers only, common-stock positions, reporting period Q4 2025
Ownership over time
| Quarter | Holders | Δ | Shares | Reported value | New | Exits |
|---|---|---|---|---|---|---|
| Q2 2026 | 112 | +7 | 44.38M | $4.90B | +14 | −8 |
| Q1 2026 | 109 | +6 | 41.83M | $3.64B | +11 | −6 |
| Q4 2025 | 102 | 0 | 43.14M | $4.62B | +3 | −2 |
| Q3 2025 | 20 | +1 | 28.88M | $2.92B | +2 | −2 |
| Q2 2025 | 17 | 0 | 22.96M | $1.45B | +1 | −1 |
| Q1 2025 | 14 | +2 | 11.52M | $610.22M | +2 | — |
| Q4 2024 | 12 | 0 | 11.40M | $638.39M | — | — |
| Q3 2024 | 11 | +3 | 9.71M | $508.75M | +3 | — |
| Q2 2024 | 8 | — | 9.56M | $392.54M | — | — |
Who holds it · Q4 2025
| # | Manager | Shares | Δ shares | Value | Their weight | Held | ||
|---|---|---|---|---|---|---|---|---|
| 1 | BlackRock ✦ (passive) | 6.30M | -0.1% | $674.07M | 0.0% | ▼ Trim | 3 | SEC ↗ ×17 |
| 2 | The Vanguard Group ✦ (passive) | 6.21M | +24.3% | $664.82M | 0.0% | ▲ Add | 3 | SEC ↗ ×5 |
| 3 | PRIMECAP Management ✦ | 3.48M | -18.4% | $372.36M | 0.3% | ▼ Trim | 7 | SEC ↗ |
| 4 | State Street Global Advisors ✦ (passive) | 2.20M | +8.4% | $235.34M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 5 | Goldman Sachs Group ✦ | 1.83M | -3.3% | $195.98M | 0.0% | ▼ Trim | 2 | SEC ↗ ×3 |
| 6 | Fidelity (FMR) ✦ | 1.71M | -20.5% | $182.64M | 0.0% | ▼ Trim | 3 | SEC ↗ ×4 |
| 7 | Federated Hermes, Inc. | 1.62M | — | $173.82M | 0.3% | n/c | 1 | SEC ↗ ×3 |
| 8 | T. Rowe Price ✦ | 1.56M | +11.5% | $167.07M | 0.0% | ▲ Add | 7 | SEC ↗ ×2 |
| 9 | JPMorgan Chase ✦ | 1.42M | -40.1% | $152.42M | 0.0% | ▼ Trim | 2 | SEC ↗ ×5 |
| 10 | Geode Capital Management ✦ (passive) | 1.38M | +0.9% | $147.28M | 0.0% | ▲ Add | 7 | SEC ↗ ×2 |
| 11 | Janus Henderson Group Plc | 1.13M | — | $120.59M | 0.1% | n/c | 1 | SEC ↗ ×2 |
| 12 | Capital Research Global Investors | 985.09K | — | $105.44M | 0.0% | n/c | 1 | SEC ↗ |
| 13 | Alliancebernstein L.P. | 930.23K | — | $99.57M | 0.0% | n/c | 1 | SEC ↗ |
| 14 | Jennison Associates Llc | 918.57K | — | $98.32M | 0.1% | n/c | 1 | SEC ↗ ×2 |
| 15 | Franklin Resources Inc | 695.74K | — | $74.47M | 0.0% | n/c | 1 | SEC ↗ ×6 |
| 16 | Morgan Stanley ✦ | 651.40K | +40.0% | $69.73M | 0.0% | ▲ Add | 2 | SEC ↗ ×7 |
| 17 | Adage Capital Partners ✦ | 621.59K | +14.3% | $66.53M | 0.1% | ▲ Add | 3 | SEC ↗ |
| 18 | Pictet Asset Management Holding SA | 614.66K | — | $66.19M | 0.1% | n/c | 1 | SEC ↗ |
| 19 | UBS AM, a distinct business unit of… | 549.02K | — | $58.77M | 0.0% | n/c | 1 | SEC ↗ ×8 |
| 20 | Charles Schwab Investment… | 532.45K | — | $56.99M | 0.0% | n/c | 1 | SEC ↗ |
| 21 | Clearbridge Investments, LLC | 506.11K | — | $54.17M | 0.0% | n/c | 1 | SEC ↗ |
| 22 | Loomis Sayles & Co L P | 503.90K | — | $53.94M | 0.1% | n/c | 1 | SEC ↗ ×2 |
| 23 | Northern Trust Corp | 488.22K | — | $52.26M | 0.0% | n/c | 1 | SEC ↗ ×6 |
| 24 | Point72 Asset Management ✦ | 429.42K | New | $45.97M | 0.1% | New | 1 | SEC ↗ |
| 25 | UBS Group AG | 427.24K | — | $45.73M | 0.0% | n/c | 1 | SEC ↗ ×4 |
| 26 | Renaissance Technologies ✦ | 341.19K | -37.6% | $36.52M | 0.1% | ▼ Trim | 4 | SEC ↗ |
| 27 | Qube Research & Technologies Ltd | 310.92K | — | $33.28M | 0.0% | n/c | 1 | SEC ↗ |
| 28 | Bank of New York Mellon Corp | 301.08K | — | $32.23M | 0.0% | n/c | 1 | SEC ↗ ×12 |
| 29 | Invesco Ltd. | 291.15K | — | $31.16M | 0.0% | n/c | 1 | SEC ↗ ×5 |
| 30 | Artisan Partners Limited Partnership | 263.59K | — | $28.21M | 0.0% | n/c | 1 | SEC ↗ |
| 31 | Ameriprise Financial Inc | 261.16K | — | $27.95M | 0.0% | n/c | 1 | SEC ↗ ×4 |
| 32 | Wellington Management ✦ | 250.16K | +922.0% | $26.78M | 0.0% | ▲ Add | 7 | SEC ↗ ×7 |
| 33 | Voya Investment Management Llc | 249.87K | — | $26.75M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 34 | Bank Of America Corp /De/ | 224.48K | — | $24.03M | 0.0% | n/c | 1 | SEC ↗ ×7 |
| 35 | Millennium Management ✦ | 186.71K | +40.2% | $19.99M | 0.0% | ▲ Add | 6 | SEC ↗ |
| 36 | Bnp Paribas Financial Markets | 164.56K | — | $17.61M | 0.0% | n/c | 1 | SEC ↗ |
| 37 | Citadel Advisors ✦ | 153.32K | +15.6% | $16.41M | 0.0% | ▲ Add | 2 | SEC ↗ ×2 |
| 38 | Connor, Clark & Lunn Investment… | 149.37K | — | $15.99M | 0.0% | n/c | 1 | SEC ↗ |
| 39 | Russell Investments Group, Ltd. | 134.18K | — | $14.36M | 0.0% | n/c | 1 | SEC ↗ ×6 |
| 40 | Barclays Plc | 131.44K | — | $14.07M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 41 | Deutsche Bank Ag\ | 129.12K | — | $13.82M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 42 | Universal- Beteiligungs- und… | 123.54K | — | $13.22M | 0.0% | n/c | 1 | SEC ↗ |
| 43 | Nuveen, LLC | 115.93K | — | $12.41M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 44 | Capital World Investors ✦ | 115.69K | New | $12.38M | 0.0% | New | 1 | SEC ↗ |
| 45 | Swiss National Bank | 111.30K | — | $11.91M | 0.0% | n/c | 1 | SEC ↗ |
| 46 | New York State Common Retirement… | 93.68K | — | $10.03M | 0.0% | n/c | 1 | SEC ↗ |
| 47 | First Trust Advisors Lp | 88.50K | — | $9.47M | 0.0% | n/c | 1 | SEC ↗ |
| 48 | Neuberger Berman Group LLC | 73.57K | — | $7.88M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 49 | Wells Fargo & Company/Mn | 72.62K | — | $7.77M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 50 | Balyasny Asset Management L.P. | 72.28K | — | $7.74M | 0.0% | n/c | 1 | SEC ↗ |
| 51 | Rhumbline Advisers | 71.21K | — | $7.62M | 0.0% | n/c | 1 | SEC ↗ |
| 52 | AQR Capital Management ✦ | 70.05K | -12.2% | $7.50M | 0.0% | ▼ Trim | 7 | SEC ↗ ×6 |
| 53 | Norges Bank ✦ (passive) | 66.21K | New | $7.09M | 0.0% | New | 1 | SEC ↗ |
| 54 | Manufacturers Life Insurance… | 59.61K | — | $6.37M | 0.0% | n/c | 1 | SEC ↗ |
| 55 | Legal & General Group Plc | 55.08K | — | $5.90M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 56 | Td Asset Management Inc | 55.05K | — | $5.89M | 0.0% | n/c | 1 | SEC ↗ |
| 57 | California State Teachers… | 53.54K | — | $5.73M | 0.0% | n/c | 1 | SEC ↗ |
| 58 | Prudential Financial Inc | 53.15K | — | $5.69M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 59 | Victory Capital Management Inc | 45.38K | — | $4.86M | 0.0% | n/c | 1 | SEC ↗ |
| 60 | Wcm Investment Management, Llc | 44.80K | — | $4.78M | 0.0% | n/c | 1 | SEC ↗ |
| 61 | Raymond James Financial Inc | 41.12K | — | $4.40M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 62 | Sei Investments Co | 37.43K | — | $4.01M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 63 | State Of Wisconsin Investment Board | 36.08K | — | $3.86M | 0.0% | n/c | 1 | SEC ↗ |
| 64 | MIRAE ASSET GLOBAL ETFS HOLDINGS… | 34.90K | — | $3.73M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 65 | Squarepoint Ops LLC | 32.83K | — | $3.51M | 0.0% | n/c | 1 | SEC ↗ |
| 66 | Dimensional Fund Advisors Lp | 32.02K | — | $3.43M | 0.0% | n/c | 1 | SEC ↗ |
| 67 | D. E. Shaw & Co. ✦ | 31.36K | +774.6% | $3.36M | 0.0% | ▲ Add | 6 | SEC ↗ ×2 |
| 68 | Lazard Asset Management Llc | 25.57K | — | $2.74M | 0.0% | n/c | 1 | SEC ↗ |
| 69 | Creative Planning | 25.21K | — | $2.70M | 0.0% | n/c | 1 | SEC ↗ |
| 70 | Captrust Financial Advisors | 18.32K | — | $1.96M | 0.0% | n/c | 1 | SEC ↗ |
| 71 | State Board Of Administration Of… | 14.65K | — | $1.57M | 0.0% | n/c | 1 | SEC ↗ |
| 72 | Stifel Financial Corp | 13.25K | — | $1.42M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 73 | Citigroup Inc | 12.72K | — | $1.36M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 74 | ProShare Advisors LLC | 12.62K | — | $1.35M | 0.0% | n/c | 1 | SEC ↗ |
| 75 | Zurcher Kantonalbank (Zurich… | 12.44K | — | $1.33M | 0.0% | n/c | 1 | SEC ↗ |
| 76 | Rockefeller Capital Management L.P. | 11.77K | — | $1.26M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 77 | Man Group plc | 9.56K | — | $1.02M | 0.0% | n/c | 1 | SEC ↗ |
| 78 | Allianz Asset Management GmbH | 8.00K | — | $856,320 | 0.0% | n/c | 1 | SEC ↗ |
| 79 | Principal Financial Group Inc | 6.20K | — | $663,434 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 80 | LPL Financial LLC | 5.43K | — | $580,906 | 0.0% | n/c | 1 | SEC ↗ |
| 81 | Gotham Asset Management ✦ | 4.85K | -0.1% | $519,251 | 0.0% | ▼ Trim | 7 | SEC ↗ |
| 82 | Pnc Financial Services Group, Inc. | 4.66K | — | $498,699 | 0.0% | n/c | 1 | SEC ↗ ×4 |
| 83 | Mackenzie Financial Corp | 4.40K | — | $468,607 | 0.0% | n/c | 1 | SEC ↗ |
| 84 | Susquehanna International Group, Llp | 4.10K | — | $438,543 | 0.0% | n/c | 1 | SEC ↗ |
| 85 | Ensign Peak Advisors, Inc | 3.86K | — | $413,067 | 0.0% | n/c | 1 | SEC ↗ |
| 86 | Quantinno Capital Management LP | 3.83K | — | $410,070 | 0.0% | n/c | 1 | SEC ↗ |
| 87 | Cerity Partners LLC | 3.66K | — | $392,194 | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 88 | Tidal Investments LLC | 3.34K | — | $357,085 | 0.0% | n/c | 1 | SEC ↗ |
| 89 | Mirae Asset Global Investments Co.… | 3.24K | — | $347,131 | 0.0% | n/c | 1 | SEC ↗ |
| 90 | CIBC Asset Management Inc | 2.85K | — | $304,850 | 0.0% | n/c | 1 | SEC ↗ |
| 91 | Cwm, Llc | 2.77K | — | $296,000 | 0.0% | n/c | 1 | SEC ↗ |
| 92 | BNP Paribas Asset Management… | 2.42K | — | $259,000 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 93 | Jane Street Group, Llc | 1.96K | — | $209,798 | 0.0% | n/c | 1 | SEC ↗ |
| 94 | Royal Bank Of Canada | 1.68K | — | $180,000 | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 95 | Danske Bank A/S | 1.10K | — | $117,744 | 0.0% | n/c | 1 | SEC ↗ |
| 96 | Osaic Holdings, Inc. | 1.04K | — | $111,214 | 0.0% | n/c | 1 | SEC ↗ |
| 97 | Us Bancorp \De\ | 953 | — | $102,009 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 98 | Jones Financial Companies Lllp | 231 | — | $24,726 | 0.0% | n/c | 1 | SEC ↗ |
| 99 | Daiwa Securities Group Inc. | 201 | — | $22,000 | 0.0% | n/c | 1 | SEC ↗ |
| 100 | Optiver Holding B.V. | 92 | — | $9,848 | 0.0% | n/c | 1 | SEC ↗ |
“Their weight” = the position's share of that manager's reported 13F equity value — the conviction measure. ✦ = curated manager.
New buyers
| Point72 Asset Management | $45.97M | 0.1% |
| Capital World Investors | $12.38M | 0.0% |
| Norges Bank | $7.09M | 0.0% |
Exited
| Marshall Wace | $17.35M | was 0.0% |
| Arrowstreet Capital | $636,944 | was 0.0% |
Full-market context: across ALL 13F filers (SEC structured data, Q1 2026): 284 holders, 72.02M shares, $6.12B reported. This is a different, older period than the tracked-universe figures above and the two are never mixed.
Frequently co-owned
What else this security's tracked holders most often hold — shared-ownership counts, not fundamental relationships.
Open-market purchases (P)
No open-market insider purchases in our coverage window.
Open-market sales (S)
Sep 14
Meeker David P
Officer, Director · 1.82K sh · $189,965
Sep 14
Meeker David P
Officer, Director · 8.70K sh · $899,634
Sep 14
Meeker David P
Officer, Director · 30.75K sh · $3.15M
Sep 14
Meeker David P
Officer, Director · 6.44K sh · $655,145
Sep 14
Meeker David P
Officer, Director · 2.30K sh · $241,937
Aug 31
Smith Hunter C
Officer · 11.51K sh · $1.21M
Aug 31
Smith Hunter C
Officer · 23.07K sh · $2.41M
Aug 31
Smith Hunter C
Officer · 28.19K sh · $2.99M
Aug 13
Garfield Alastair
Officer · 2.01K sh · $233,031
Aug 13
Garfield Alastair
Officer · 1.56K sh · $182,170
Awards, exercises and tax withholding are never counted as buys or sales here. Methodology
Oct 13
SC 13G — JPMORGAN CHASE & CO
Provenance: Ownership from parsed 13F common-stock positions (tracked universe, comparable sets for changes); insider rows from Forms 3/4/5; stakes from Schedules 13D/13G; every filing links to its original on SEC EDGAR.
Reporting period: Q4 2025 ·
Methodology ·
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