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Security record

AMLX

Amylyx Pharmaceuticals, Inc. · Healthcare · Biotechnology

28.14 +3.5% mkt cap $3.13B quote delayed (FMP) · as of Oct 11 03:53 UTC — separate from filing data below

Q2 2026 Q1 2026 Q4 2025 Q3 2025 Q2 2025 Q1 2025 Q4 2024 Q3 2024
79Tracked holders
+11Δ holders
60.68MShares held
$1.09BReported value
+14New positions
−2Exits
Strongly Rising Conviction score 52/100 How these are computed → Explain this at the Research Desk →

Momentum inputs (comparable managers): holder breadth +16.2% · share flow +5.3% · net new positions +15.2% — formula
Broad accumulation — rising shares across more holders

All ownership figures: tracked 13F managers only, common-stock positions, reporting period Q2 2026

Ownership over time
QuarterHoldersΔSharesReported valueNewExits
Q2 2026 79 +11 60.68M $1.09B +14 −2
Q1 2026 70 -3 62.54M $868.96M +6 −9
Q4 2025 73 0 62.47M $754.72M — —
Q3 2025 18 +1 42.12M $572.37M +1 —
Q2 2025 14 -1 33.34M $213.68M — −1
Q1 2025 12 +1 15.66M $55.46M +2 −1
Q4 2024 11 0 5.41M $20.47M +1 −1
Q3 2024 10 +2 5.23M $16.93M +2 —
Q2 2024 8 — 10.16M $19.31M — —
Holder count
Who holds it · Q2 2026
#ManagerSharesΔ sharesValueTheir weightHeld
1 Fidelity (FMR) ✦ 16.73M +0.6% $300.43M 0.0% ▲ Add 5 SEC ↗ ×5
2 BlackRock ✦ (passive) 8.83M 0.0% $158.53M 0.0% ▼ Trim 5 SEC ↗ ×13
3 Vanguard Capital Management Llc 4.22M +2.0% $75.87M 0.0% ▲ Add 2 SEC ↗
4 Morgan Stanley ✦ 3.13M +43.9% $56.23M 0.0% ▲ Add 4 SEC ↗ ×7
5 Franklin Resources Inc 2.95M +30.4% $52.99M 0.0% ▲ Add 3 SEC ↗ ×2
6 Goldman Sachs Group ✦ 2.86M +8.8% $51.33M 0.0% ▲ Add 4 SEC ↗ ×3
7 State Street Global Advisors ✦ (passive) 2.60M +10.2% $46.76M 0.0% ▲ Add 7 SEC ↗
8 Geode Capital Management ✦ (passive) 2.34M +5.6% $41.95M 0.0% ▲ Add 9 SEC ↗ ×2
9 JPMorgan Chase ✦ 1.86M +1067.2% $34.92M 0.0% ▲ Add 4 SEC ↗ ×4
10 Adage Capital Partners ✦ 1.90M -46.6% $34.12M 0.0% ▼ Trim 6 SEC ↗
11 Alyeska Investment Group, L.P. 1.05M New $18.91M 0.0% New 1 SEC ↗
12 Dimensional Fund Advisors Lp 902.46K -0.1% $16.22M 0.0% ▼ Trim 3 SEC ↗ ×4
13 Northern Trust Corp 831.74K +6.7% $14.94M 0.0% ▲ Add 3 SEC ↗ ×5
14 Bank Of America Corp /De/ 821.84K -38.2% $14.76M 0.0% ▼ Trim 3 SEC ↗ ×3
15 Aberdeen Group plc 737.67K New $13.25M 0.0% New 1 SEC ↗
16 Charles Schwab Investment… 725.03K +1.2% $13.02M 0.0% ▲ Add 3 SEC ↗
17 Connor, Clark & Lunn Investment… 721.00K -17.0% $12.95M 0.0% ▼ Trim 3 SEC ↗
18 Balyasny Asset Management L.P. 684.97K -38.1% $12.30M 0.0% ▼ Trim 3 SEC ↗
19 Qube Research & Technologies Ltd 681.39K -3.0% $12.24M 0.0% ▼ Trim 3 SEC ↗
20 Two Sigma Investments ✦ 593.43K +266.4% $10.66M 0.0% ▲ Add 9 SEC ↗
21 Deutsche Bank Ag\ 557.94K -56.0% $10.02M 0.0% ▼ Trim 3 SEC ↗ ×2
22 Federated Hermes, Inc. 462.20K +27.1% $8.30M 0.0% ▲ Add 3 SEC ↗ ×2
23 Nuveen, LLC 330.52K +24.8% $5.94M 0.0% ▲ Add 3 SEC ↗ ×3
24 Ensign Peak Advisors, Inc 305.44K New $5.49M 0.0% New 1 SEC ↗
25 Jane Street Group, Llc 299.56K New $5.38M 0.0% New 1 SEC ↗ ×2
26 Bank of New York Mellon Corp 274.44K +9.3% $4.93M 0.0% ▲ Add 3 SEC ↗ ×5
27 UBS Group AG 271.88K -16.2% $4.88M 0.0% ▼ Trim 3 SEC ↗ ×3
28 First Trust Advisors Lp 254.59K New $4.57M 0.0% New 1 SEC ↗
29 Wellington Management ✦ 212.84K -11.9% $3.82M 0.0% ▼ Trim 7 SEC ↗ ×3
30 Citadel Advisors ✦ 178.69K -56.6% $3.21M 0.0% ▼ Trim 9 SEC ↗ ×2
31 D. E. Shaw & Co. ✦ 174.28K +134.8% $3.13M 0.0% ▲ Add 9 SEC ↗ ×2
32 UBS AM, a distinct business unit of… 173.41K +10.4% $3.11M 0.0% ▲ Add 3 SEC ↗ ×8
33 Norges Bank ✦ (passive) 159.90K New $2.87M 0.0% New 1 SEC ↗
34 T. Rowe Price ✦ 145.13K +19.5% $2.61M 0.0% ▲ Add 9 SEC ↗
35 Swiss National Bank 144.20K +10.7% $2.59M 0.0% ▲ Add 3 SEC ↗
36 Invesco Ltd. 139.94K -18.5% $2.51M 0.0% ▼ Trim 3 SEC ↗ ×4
37 Wells Fargo & Company/Mn 128.16K +70.7% $2.30M 0.0% ▲ Add 3 SEC ↗ ×4
38 Ameriprise Financial Inc 125.48K New $2.25M 0.0% New 1 SEC ↗
39 Rhumbline Advisers 112.92K +4.1% $2.03M 0.0% ▲ Add 3 SEC ↗
40 Russell Investments Group, Ltd. 87.57K +47.6% $1.57M 0.0% ▲ Add 3 SEC ↗ ×5
41 Quantinno Capital Management LP 80.85K New $1.45M 0.0% New 1 SEC ↗
42 Alliancebernstein L.P. 104.40K +29.2% $1.45M 0.0% ▲ Add 3 SEC ↗
43 Citigroup Inc 68.68K +116.1% $1.23M 0.0% ▲ Add 3 SEC ↗ ×2
44 State Of Wisconsin Investment Board 61.28K -15.0% $1.10M 0.0% ▼ Trim 3 SEC ↗
45 Corient Private Wealth LP 59.32K New $1.07M 0.0% New 1 SEC ↗
46 Legal & General Group Plc 56.48K +1.3% $1.01M 0.0% ▲ Add 3 SEC ↗ ×3
47 Barclays Plc 56.26K -94.2% $1.01M 0.0% ▼ Trim 3 SEC ↗ ×2
48 MIRAE ASSET GLOBAL ETFS HOLDINGS… 42.35K -0.5% $760,624 0.0% ▼ Trim 3 SEC ↗
49 Manufacturers Life Insurance… 37.83K -2.5% $679,391 0.0% ▼ Trim 3 SEC ↗
50 Jennison Associates Llc 35.84K New $643,705 0.0% New 1 SEC ↗
51 Tudor Investment Corp Et Al 35.41K +13.0% $635,964 0.0% ▲ Add 3 SEC ↗
52 New York State Common Retirement… 34.30K +56.6% $616,028 0.0% ▲ Add 3 SEC ↗
53 Canada Pension Plan Investment Board 27.60K New $495,696 0.0% New 1 SEC ↗
54 Hrt Financial Lp 23.87K New $428,000 0.0% New 1 SEC ↗
55 AQR Capital Management ✦ 20.82K -28.4% $373,909 0.0% ▼ Trim 4 SEC ↗ ×4
56 Brown Advisory Inc 19.93K 0.0% $357,943 0.0% Held 3 SEC ↗
57 Sei Investments Co 19.75K -76.8% $354,710 0.0% ▼ Trim 3 SEC ↗
58 Voya Investment Management Llc 17.85K +17.2% $320,532 0.0% ▲ Add 3 SEC ↗
59 Zurcher Kantonalbank (Zurich… 16.96K -58.4% $304,530 0.0% ▼ Trim 3 SEC ↗
60 Bnp Paribas Financial Markets 16.58K -21.6% $297,723 0.0% ▼ Trim 3 SEC ↗
61 Creative Planning 15.88K -11.2% $285,223 0.0% ▼ Trim 2 SEC ↗ ×2
62 ProShare Advisors LLC 15.69K -13.6% $281,702 0.0% ▼ Trim 3 SEC ↗
63 Prudential Financial Inc 15.11K +7.0% $271,376 0.0% ▲ Add 2 SEC ↗
64 Hsbc Holdings Plc 14.55K +27.5% $268,958 0.0% ▲ Add 2 SEC ↗
65 Royal Bank Of Canada 14.65K +18.3% $263,000 0.0% ▲ Add 3 SEC ↗ ×4
66 Amundi 12.89K 0.0% $231,594 0.0% Held 2 SEC ↗
67 Pictet Asset Management Holding SA 10.77K 0.0% $193,393 0.0% Held 2 SEC ↗
68 Victory Capital Management Inc 10.71K +0.6% $192,298 0.0% ▲ Add 3 SEC ↗
69 Susquehanna International Group, Llp 10.34K -74.0% $185,688 0.0% ▼ Trim 3 SEC ↗
70 Mirae Asset Global Investments Co.… 4.97K -13.2% $89,315 0.0% ▼ Trim 3 SEC ↗
71 Us Bancorp \De\ 3.64K +76.4% $65,357 0.0% ▲ Add 3 SEC ↗ ×2
72 Group One Trading Llc 1.62K New $29,167 0.0% New 1 SEC ↗
73 BNP Paribas Asset Management… 1.35K -4.7% $24,264 0.0% ▼ Trim 3 SEC ↗
74 Rockefeller Capital Management L.P. 1.27K 0.0% $22,881 0.0% Held 3 SEC ↗ ×2
75 Fifth Third Bancorp 972 +28.7% $17,457 0.0% ▲ Add 2 SEC ↗
76 Jones Financial Companies Lllp 597 +121.1% $10,621 0.0% ▲ Add 3 SEC ↗
77 Osaic Holdings, Inc. 483 -8.5% $8,674 0.0% ▼ Trim 3 SEC ↗ ×2
78 Pnc Financial Services Group, Inc. 406 +43.5% $7,292 0.0% ▲ Add 3 SEC ↗
79 Optiver Holding B.V. 220 New $3,951 0.0% New 1 SEC ↗

“Their weight” = the position's share of that manager's reported 13F equity value — the conviction measure. ✦ = curated manager.

New buyers

Exited

Squarepoint Ops LLC $1.60M was 0.0%
Point72 Asset Management $1.48M was 0.0%

Full-market context: across ALL 13F filers (SEC structured data, Q1 2026): 170 holders, 113.99M shares, $1.58B reported. This is a different, older period than the tracked-universe figures above and the two are never mixed.

Frequently co-owned

What else this security's tracked holders most often hold — shared-ownership counts, not fundamental relationships.

Insider transactions

Open-market purchases (P)

No open-market insider purchases in our coverage window.

Open-market sales (S)

Oct 05 MILNE GEORGE M JR

Director · 30.00K sh · $830,904

Sep 10 Cohen Joshua B

Officer, Director · 29.55K sh · $950,040

Sep 10 Cohen Joshua B

Officer, Director · 919 sh · $30,464

Sep 10 Mazzariello Gina

Officer · 9.53K sh · $309,140

Sep 10 Mazzariello Gina

Officer · 11 sh · $367

Sep 10 FRATES JAMES M

Officer · 9.77K sh · $315,195

Sep 10 FRATES JAMES M

Officer · 1.04K sh · $34,626

Sep 10 Bedrosian Camille L

Officer · 7.95K sh · $256,004

Sep 10 Bedrosian Camille L

Officer · 2.08K sh · $68,864

Sep 10 Klee Justin B.

Officer, Director · 29.02K sh · $932,553

Awards, exercises and tax withholding are never counted as buys or sales here. Methodology

Provenance: Ownership from parsed 13F common-stock positions (tracked universe, comparable sets for changes); insider rows from Forms 3/4/5; stakes from Schedules 13D/13G; every filing links to its original on SEC EDGAR. Reporting period: Q2 2026 · Methodology · Get this via the API