AMLX
Amylyx Pharmaceuticals, Inc. · Healthcare · Biotechnology
Momentum inputs (comparable managers):
holder breadth +5.9% ·
share flow +12.7% ·
net new positions +5.6%
— formula
Broad accumulation — rising shares across more holders
All ownership figures: tracked 13F managers only, common-stock positions, reporting period Q3 2025
| Quarter | Holders | Δ | Shares | Reported value | New | Exits |
|---|---|---|---|---|---|---|
| Q2 2026 | 78 | +11 | 60.67M | $1.09B | +14 | −3 |
| Q1 2026 | 70 | -3 | 62.54M | $868.96M | +6 | −9 |
| Q4 2025 | 73 | 0 | 62.47M | $754.72M | — | — |
| Q3 2025 | 18 | +1 | 42.12M | $572.37M | +1 | — |
| Q2 2025 | 14 | -1 | 33.34M | $213.68M | — | −1 |
| Q1 2025 | 12 | +1 | 15.66M | $55.46M | +2 | −1 |
| Q4 2024 | 11 | 0 | 5.41M | $20.47M | +1 | −1 |
| Q3 2024 | 10 | +2 | 5.23M | $16.93M | +2 | — |
| Q2 2024 | 8 | — | 10.16M | $19.31M | — | — |
| # | Manager | Shares | Δ shares | Value | Their weight | Held | ||
|---|---|---|---|---|---|---|---|---|
| 1 | Fidelity (FMR) ✦ | 11.38M | +273.3% | $154.64M | 0.0% | ▲ Add | 2 | SEC ↗ ×5 |
| 2 | BlackRock ✦ (passive) | 7.14M | +29.6% | $97.04M | 0.0% | ▲ Add | 2 | SEC ↗ ×10 |
| 3 | Adage Capital Partners ✦ | 6.82M | -22.5% | $92.64M | 0.1% | ▼ Trim | 3 | SEC ↗ |
| 4 | The Vanguard Group ✦ (passive) | 5.27M | +17.2% | $71.67M | 0.0% | ▲ Add | 2 | SEC ↗ ×3 |
| 5 | Point72 Asset Management ✦ | 2.79M | -38.5% | $37.92M | 0.1% | ▼ Trim | 3 | SEC ↗ |
| 6 | Goldman Sachs Group ✦ | 2.01M | — | $27.32M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 7 | Morgan Stanley ✦ | 1.95M | — | $26.50M | 0.0% | n/c | 1 | SEC ↗ ×8 |
| 8 | Geode Capital Management ✦ (passive) | 1.81M | +7.1% | $24.63M | 0.0% | ▲ Add | 6 | SEC ↗ ×2 |
| 9 | State Street Global Advisors ✦ (passive) | 1.62M | +60.7% | $22.03M | 0.0% | ▲ Add | 4 | SEC ↗ |
| 10 | Millennium Management ✦ | 417.77K | -72.4% | $5.68M | 0.0% | ▼ Trim | 6 | SEC ↗ |
| 11 | Wellington Management ✦ | 236.20K | -18.2% | $3.21M | 0.0% | ▼ Trim | 4 | SEC ↗ ×3 |
| 12 | Citadel Advisors ✦ | 234.67K | -81.1% | $3.19M | 0.0% | ▼ Trim | 6 | SEC ↗ ×2 |
| 13 | T. Rowe Price ✦ | 100.44K | +9.9% | $1.37M | 0.0% | ▲ Add | 6 | SEC ↗ |
| 14 | Two Sigma Investments ✦ | 98.42K | -82.4% | $1.34M | 0.0% | ▼ Trim | 6 | SEC ↗ |
| 15 | AQR Capital Management ✦ | 73.64K | New | $1.00M | 0.0% | New | 1 | SEC ↗ ×4 |
| 16 | JPMorgan Chase ✦ | 71.69K | — | $974,238 | 0.0% | n/c | 1 | SEC ↗ ×6 |
| 17 | D. E. Shaw & Co. ✦ | 68.88K | -54.5% | $936,038 | 0.0% | ▼ Trim | 6 | SEC ↗ |
| 18 | Renaissance Technologies ✦ | 19.90K | -95.0% | $270,441 | 0.0% | ▼ Trim | 6 | SEC ↗ |
“Their weight” = the position's share of that manager's reported 13F equity value — the conviction measure. ✦ = curated manager.
New buyers
| AQR Capital Management | $1.00M | 0.0% |
Exited
| No tracked exits this quarter. |
Full-market context: across ALL 13F filers (SEC structured data, Q1 2026): 170 holders, 113.99M shares, $1.58B reported. This is a different, older period than the tracked-universe figures above and the two are never mixed.
What else this security's tracked holders most often hold — shared-ownership counts, not fundamental relationships.
Open-market purchases (P)
No open-market insider purchases in our coverage window.
Open-market sales (S)
Director · 30.00K sh · $830,904
Officer, Director · 29.55K sh · $950,040
Officer, Director · 919 sh · $30,464
Officer · 9.53K sh · $309,140
Officer · 11 sh · $367
Officer · 9.77K sh · $315,195
Officer · 1.04K sh · $34,626
Officer · 7.95K sh · $256,004
Officer · 2.08K sh · $68,864
Officer, Director · 29.02K sh · $932,553
Awards, exercises and tax withholding are never counted as buys or sales here. Methodology