Security record · archived quarter
AMLX
Amylyx Pharmaceuticals, Inc. · Healthcare · Biotechnology
70Tracked holders
-3Δ holders
62.54MShares held
$868.96MReported value
+6New positions
−9Exits
Momentum inputs (comparable managers):
holder breadth -4.1% ·
share flow +2.9% ·
net new positions -4.3%
· formula
Concentrated accumulation: rising shares among fewer holders
All ownership figures: tracked 13F managers only, common-stock positions, reporting period Q1 2026
Ownership over time
| Quarter | Holders | Δ | Shares | Reported value | New | Exits |
|---|---|---|---|---|---|---|
| Q2 2026 | 79 | +11 | 60.68M | $1.09B | +14 | −2 |
| Q1 2026 | 70 | -3 | 62.54M | $868.96M | +6 | −9 |
| Q4 2025 | 73 | 0 | 62.47M | $754.72M | n/a | n/a |
| Q3 2025 | 18 | +1 | 42.12M | $572.37M | +1 | n/a |
| Q2 2025 | 14 | -1 | 33.34M | $213.68M | n/a | −1 |
| Q1 2025 | 12 | +1 | 15.66M | $55.46M | +2 | −1 |
| Q4 2024 | 11 | 0 | 5.41M | $20.47M | +1 | −1 |
| Q3 2024 | 10 | +2 | 5.23M | $16.93M | +2 | n/a |
| Q2 2024 | 8 | n/a | 10.16M | $19.31M | n/a | n/a |
Who holds it · Q1 2026
| # | Manager | Shares | Δ shares | Value | Their weight | Held | ||
|---|---|---|---|---|---|---|---|---|
| 1 | Fidelity (FMR) ✦ | 16.63M | +0.7% | $231.16M | 0.0% | ▲ Add | 4 | SEC ↗ ×5 |
| 2 | BlackRock ✦ (passive) | 8.83M | -2.5% | $122.72M | 0.0% | ▼ Trim | 4 | SEC ↗ ×13 |
| 3 | Janus Henderson Group Plc | 4.99M | +11.7% | $69.26M | 0.0% | ▲ Add | 2 | SEC ↗ ×2 |
| 4 | Vanguard Capital Management Llc | 4.14M | n/a | $57.57M | 0.0% | n/c | 1 | SEC ↗ |
| 5 | Adage Capital Partners ✦ | 3.56M | +28.2% | $49.49M | 0.1% | ▲ Add | 5 | SEC ↗ |
| 6 | Goldman Sachs Group ✦ | 2.63M | +0.5% | $36.50M | 0.0% | ▲ Add | 3 | SEC ↗ ×3 |
| 7 | State Street Global Advisors ✦ (passive) | 2.36M | +14.2% | $32.85M | 0.0% | ▲ Add | 6 | SEC ↗ |
| 8 | Franklin Resources Inc | 2.26M | +88.5% | $31.44M | 0.0% | ▲ Add | 2 | SEC ↗ ×3 |
| 9 | Geode Capital Management ✦ (passive) | 2.21M | +2.1% | $30.74M | 0.0% | ▲ Add | 8 | SEC ↗ ×2 |
| 10 | Morgan Stanley ✦ | 2.18M | -7.8% | $30.24M | 0.0% | ▼ Trim | 3 | SEC ↗ ×8 |
| 11 | Bank Of America Corp /De/ | 1.33M | -0.4% | $18.50M | 0.0% | ▼ Trim | 2 | SEC ↗ ×3 |
| 12 | Deutsche Bank Ag\ | 1.27M | -4.9% | $17.62M | 0.0% | ▼ Trim | 2 | SEC ↗ ×2 |
| 13 | Balyasny Asset Management L.P. | 1.11M | +28.9% | $15.39M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 14 | Barclays Plc | 971.85K | +229.2% | $13.51M | 0.0% | ▲ Add | 2 | SEC ↗ ×2 |
| 15 | Dimensional Fund Advisors Lp | 903.19K | +17.1% | $12.54M | 0.0% | ▲ Add | 2 | SEC ↗ ×4 |
| 16 | Connor, Clark & Lunn Investment… | 868.33K | -13.5% | $12.07M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 17 | Northern Trust Corp | 779.91K | -16.8% | $10.84M | 0.0% | ▼ Trim | 2 | SEC ↗ ×5 |
| 18 | Charles Schwab Investment… | 716.23K | +0.5% | $9.96M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 19 | Qube Research & Technologies Ltd | 702.24K | +70.1% | $9.76M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 20 | Citadel Advisors ✦ | 411.53K | +19.3% | $5.72M | 0.0% | ▲ Add | 8 | SEC ↗ ×2 |
| 21 | Federated Hermes, Inc. | 363.55K | -20.5% | $5.05M | 0.0% | ▼ Trim | 2 | SEC ↗ ×2 |
| 22 | UBS Group AG | 324.32K | -40.3% | $4.51M | 0.0% | ▼ Trim | 2 | SEC ↗ ×2 |
| 23 | Nuveen, LLC | 264.90K | -6.7% | $3.68M | 0.0% | ▼ Trim | 2 | SEC ↗ ×2 |
| 24 | Bank of New York Mellon Corp | 251.10K | +15.5% | $3.49M | 0.0% | ▲ Add | 2 | SEC ↗ ×5 |
| 25 | Wellington Management ✦ | 241.55K | +7.0% | $3.36M | 0.0% | ▲ Add | 6 | SEC ↗ ×3 |
| 26 | Invesco Ltd. | 171.62K | -2.4% | $2.39M | 0.0% | ▼ Trim | 2 | SEC ↗ ×4 |
| 27 | Two Sigma Investments ✦ | 161.94K | -53.0% | $2.25M | 0.0% | ▼ Trim | 8 | SEC ↗ |
| 28 | UBS AM, a distinct business unit of… | 157.09K | +58.9% | $2.18M | 0.0% | ▲ Add | 2 | SEC ↗ ×7 |
| 29 | JPMorgan Chase ✦ | 159.66K | +139.9% | $2.04M | 0.0% | ▲ Add | 3 | SEC ↗ ×3 |
| 30 | Swiss National Bank | 130.30K | -19.4% | $1.81M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 31 | T. Rowe Price ✦ | 121.44K | +12.9% | $1.69M | 0.0% | ▲ Add | 8 | SEC ↗ |
| 32 | Squarepoint Ops LLC | 114.88K | +50.0% | $1.60M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 33 | Rhumbline Advisers | 108.47K | +9.3% | $1.51M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 34 | Point72 Asset Management ✦ | 106.53K | -68.2% | $1.48M | 0.0% | ▼ Trim | 5 | SEC ↗ |
| 35 | Sei Investments Co | 85.28K | +61.3% | $1.19M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 36 | Wells Fargo & Company/Mn | 75.08K | -48.7% | $1.04M | 0.0% | ▼ Trim | 2 | SEC ↗ ×4 |
| 37 | D. E. Shaw & Co. ✦ | 74.23K | +1.4% | $1.03M | 0.0% | ▲ Add | 8 | SEC ↗ ×2 |
| 38 | State Of Wisconsin Investment Board | 72.06K | -14.4% | $1.00M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 39 | Alliancebernstein L.P. | 80.80K | +13.0% | $976,064 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 40 | California State Teachers… | 65.00K | -17.8% | $903,528 | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 41 | Russell Investments Group, Ltd. | 59.35K | -9.3% | $824,907 | 0.0% | ▼ Trim | 2 | SEC ↗ ×5 |
| 42 | Legal & General Group Plc | 55.77K | -23.2% | $775,244 | 0.0% | ▼ Trim | 2 | SEC ↗ ×3 |
| 43 | MIRAE ASSET GLOBAL ETFS HOLDINGS… | 42.55K | +3.4% | $591,487 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 44 | Zurcher Kantonalbank (Zurich… | 40.79K | +13.7% | $566,981 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 45 | Susquehanna International Group, Llp | 39.80K | -42.2% | $553,248 | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 46 | Manufacturers Life Insurance… | 38.78K | +43.7% | $539,056 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 47 | Citigroup Inc | 31.78K | -16.4% | $441,770 | 0.0% | ▼ Trim | 2 | SEC ↗ ×2 |
| 48 | Tudor Investment Corp Et Al | 31.33K | +39.9% | $435,543 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 49 | AQR Capital Management ✦ | 29.09K | +4.5% | $404,338 | 0.0% | ▲ Add | 3 | SEC ↗ ×4 |
| 50 | New York State Common Retirement… | 21.90K | 0.0% | $304,410 | 0.0% | Held | 2 | SEC ↗ |
| 51 | Bnp Paribas Financial Markets | 21.14K | -16.1% | $293,846 | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 52 | Brown Advisory Inc | 19.93K | 0.0% | $277,027 | 0.0% | Held | 2 | SEC ↗ |
| 53 | ProShare Advisors LLC | 18.15K | -13.8% | $252,341 | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 54 | Creative Planning | 17.88K | New | $248,574 | 0.0% | New | 1 | SEC ↗ |
| 55 | Voya Investment Management Llc | 15.23K | -0.1% | $211,655 | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 56 | Prudential Financial Inc | 14.12K | New | $196,268 | 0.0% | New | 1 | SEC ↗ |
| 57 | Amundi | 12.89K | New | $179,241 | 0.0% | New | 1 | SEC ↗ |
| 58 | Royal Bank Of Canada | 12.38K | -20.8% | $172,000 | 0.0% | ▼ Trim | 2 | SEC ↗ ×4 |
| 59 | Hsbc Holdings Plc | 11.41K | New | $156,943 | 0.0% | New | 1 | SEC ↗ |
| 60 | Pictet Asset Management Holding SA | 10.77K | New | $149,675 | 0.0% | New | 1 | SEC ↗ |
| 61 | Victory Capital Management Inc | 10.64K | +0.9% | $147,952 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 62 | Mirae Asset Global Investments Co.… | 5.73K | +7.3% | $79,619 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 63 | Us Bancorp \De\ | 2.06K | +3.1% | $28,676 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 64 | BNP Paribas Asset Management… | 1.42K | +7.8% | $19,710 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 65 | Rockefeller Capital Management L.P. | 1.27K | +388.1% | $17,708 | 0.0% | ▲ Add | 2 | SEC ↗ ×2 |
| 66 | Cwm, Llc | 1.26K | +5.9% | $17,556 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 67 | Fifth Third Bancorp | 755 | New | $10,495 | 0.0% | New | 1 | SEC ↗ |
| 68 | Osaic Holdings, Inc. | 528 | +112.0% | $7,339 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 69 | Pnc Financial Services Group, Inc. | 283 | -35.4% | $3,934 | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 70 | Jones Financial Companies Lllp | 270 | +800.0% | $3,659 | 0.0% | ▲ Add | 2 | SEC ↗ |
“Their weight” = the position's share of that manager's reported 13F equity value: the conviction measure. ✦ = curated manager.
New buyers
| Creative Planning | $248,574 | 0.0% |
| Prudential Financial Inc | $196,268 | 0.0% |
| Amundi | $179,241 | 0.0% |
| Hsbc Holdings Plc | $156,943 | 0.0% |
| Pictet Asset Management… | $149,675 | 0.0% |
| Fifth Third Bancorp | $10,495 | 0.0% |
Exited
| Ameriprise Financial Inc | $6.07M | was 0.0% |
| Jane Street Group, Llc | $3.18M | was 0.0% |
| Renaissance Technologies | $2.33M | was 0.0% |
| Bank Of Montreal /Can/ | $1.67M | was 0.0% |
| Millennium Management | $561,176 | was 0.0% |
| Mariner, LLC | $559,858 | was 0.0% |
| Simplex Trading, Llc | $45,022 | was 0.0% |
| Walleye Trading LLC | $34,126 | was 0.0% |
| Daiwa Securities Group Inc. | $3,000 | was 0.0% |
Full-market context: across ALL 13F filers (SEC structured data, Q1 2026): 170 holders, 113.99M shares, $1.58B reported. This is a different, older period than the tracked-universe figures above and the two are never mixed.
Frequently co-owned
What else this security's tracked holders most often hold: shared-ownership counts, not fundamental relationships.
Open-market purchases (P)
No open-market insider purchases in our coverage window.
Open-market sales (S)
Oct 05
MILNE GEORGE M JR
Director · 30.00K sh · $830,904
Sep 10
Cohen Joshua B
Officer, Director · 29.55K sh · $950,040
Sep 10
Cohen Joshua B
Officer, Director · 919 sh · $30,464
Sep 10
Mazzariello Gina
Officer · 9.53K sh · $309,140
Sep 10
Mazzariello Gina
Officer · 11 sh · $367
Sep 10
FRATES JAMES M
Officer · 9.77K sh · $315,195
Sep 10
FRATES JAMES M
Officer · 1.04K sh · $34,626
Sep 10
Bedrosian Camille L
Officer · 7.95K sh · $256,004
Sep 10
Bedrosian Camille L
Officer · 2.08K sh · $68,864
Sep 10
Klee Justin B.
Officer, Director · 29.02K sh · $932,553
Awards, exercises and tax withholding are never counted as buys or sales here. Methodology
Provenance: Ownership from parsed 13F common-stock positions (tracked universe, comparable sets for changes); insider rows from Forms 3/4/5; stakes from Schedules 13D/13G; every filing links to its original on SEC EDGAR.
Reporting period: Q1 2026 ·
Methodology ·
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