Security record · archived quarter
VRTX
Vertex Pharmaceuticals Incorporated · Healthcare · Biotechnology
177Tracked holders
-1Δ holders
219.78MShares held
$99.62BReported value
+2New positions
−2Exits
Momentum inputs (comparable managers):
holder breadth -0.6% ·
share flow -3.4% ·
net new positions 0.0%
— formula
Broad distribution — falling shares and fewer holders
All ownership figures: tracked 13F managers only, common-stock positions, reporting period Q4 2025
Ownership over time
| Quarter | Holders | Δ | Shares | Reported value | New | Exits |
|---|---|---|---|---|---|---|
| Q2 2026 | 175 | -1 | 212.02M | $105.17B | +5 | −5 |
| Q1 2026 | 178 | 0 | 208.95M | $93.29B | +5 | −6 |
| Q4 2025 | 177 | -1 | 219.78M | $99.62B | +2 | −2 |
| Q3 2025 | 26 | +1 | 120.93M | $47.35B | +1 | −1 |
| Q2 2025 | 23 | +1 | 112.15M | $49.92B | +3 | −2 |
| Q1 2025 | 19 | -2 | 60.41M | $29.28B | — | −2 |
| Q4 2024 | 21 | +1 | 60.08M | $24.19B | +1 | — |
| Q3 2024 | 19 | 0 | 46.24M | $21.49B | — | — |
| Q2 2024 | 19 | — | 46.47M | $21.77B | — | — |
Who holds it · Q4 2025
| # | Manager | Shares | Δ shares | Value | Their weight | Held | ||
|---|---|---|---|---|---|---|---|---|
| 1 | Capital World Investors ✦ | 25.51M | -1.6% | $11.57B | 1.6% | ▼ Trim | 7 | SEC ↗ |
| 2 | The Vanguard Group ✦ (passive) | 24.11M | -0.5% | $10.93B | 0.2% | ▼ Trim | 3 | SEC ↗ |
| 3 | The Vanguard Group ✦ (passive) | 24.11M | -0.5% | $10.93B | 0.2% | ▼ Trim | 3 | SEC ↗ |
| 4 | The Vanguard Group ✦ (passive) | 24.11M | -0.5% | $10.93B | 0.2% | ▼ Trim | 3 | SEC ↗ |
| 5 | The Vanguard Group ✦ (passive) | 24.11M | -0.5% | $10.93B | 0.2% | ▼ Trim | 3 | SEC ↗ |
| 6 | The Vanguard Group ✦ (passive) | 24.11M | -0.5% | $10.93B | 0.2% | ▼ Trim | 3 | SEC ↗ |
| 7 | The Vanguard Group ✦ (passive) | 24.11M | -0.5% | $10.93B | 0.2% | ▼ Trim | 3 | SEC ↗ |
| 8 | BlackRock ✦ (passive) | 23.75M | +6.7% | $10.77B | 0.2% | ▲ Add | 3 | SEC ↗ |
| 9 | BlackRock ✦ (passive) | 23.75M | +6.7% | $10.77B | 0.2% | ▲ Add | 3 | SEC ↗ |
| 10 | BlackRock ✦ (passive) | 23.75M | +6.7% | $10.77B | 0.2% | ▲ Add | 3 | SEC ↗ |
| 11 | BlackRock ✦ (passive) | 23.75M | +6.7% | $10.77B | 0.2% | ▲ Add | 3 | SEC ↗ |
| 12 | BlackRock ✦ (passive) | 23.75M | +6.7% | $10.77B | 0.2% | ▲ Add | 3 | SEC ↗ |
| 13 | BlackRock ✦ (passive) | 23.75M | +6.7% | $10.77B | 0.2% | ▲ Add | 3 | SEC ↗ |
| 14 | BlackRock ✦ (passive) | 23.75M | +6.7% | $10.77B | 0.2% | ▲ Add | 3 | SEC ↗ |
| 15 | BlackRock ✦ (passive) | 23.75M | +6.7% | $10.77B | 0.2% | ▲ Add | 3 | SEC ↗ |
| 16 | BlackRock ✦ (passive) | 23.75M | +6.7% | $10.77B | 0.2% | ▲ Add | 3 | SEC ↗ |
| 17 | BlackRock ✦ (passive) | 23.75M | +6.7% | $10.77B | 0.2% | ▲ Add | 3 | SEC ↗ |
| 18 | BlackRock ✦ (passive) | 23.75M | +6.7% | $10.77B | 0.2% | ▲ Add | 3 | SEC ↗ |
| 19 | BlackRock ✦ (passive) | 23.75M | +6.7% | $10.77B | 0.2% | ▲ Add | 3 | SEC ↗ |
| 20 | BlackRock ✦ (passive) | 23.75M | +6.7% | $10.77B | 0.2% | ▲ Add | 3 | SEC ↗ |
| 21 | BlackRock ✦ (passive) | 23.75M | +6.7% | $10.77B | 0.2% | ▲ Add | 3 | SEC ↗ |
| 22 | BlackRock ✦ (passive) | 23.75M | +6.7% | $10.77B | 0.2% | ▲ Add | 3 | SEC ↗ |
| 23 | BlackRock ✦ (passive) | 23.75M | +6.7% | $10.77B | 0.2% | ▲ Add | 3 | SEC ↗ |
| 24 | BlackRock ✦ (passive) | 23.75M | +6.7% | $10.77B | 0.2% | ▲ Add | 3 | SEC ↗ |
| 25 | BlackRock ✦ (passive) | 23.75M | +6.7% | $10.77B | 0.2% | ▲ Add | 3 | SEC ↗ |
| 26 | BlackRock ✦ (passive) | 23.75M | +6.7% | $10.77B | 0.2% | ▲ Add | 3 | SEC ↗ |
| 27 | BlackRock ✦ (passive) | 23.75M | +6.7% | $10.77B | 0.2% | ▲ Add | 3 | SEC ↗ |
| 28 | BlackRock ✦ (passive) | 23.75M | +6.7% | $10.77B | 0.2% | ▲ Add | 3 | SEC ↗ |
| 29 | BlackRock ✦ (passive) | 23.75M | +6.7% | $10.77B | 0.2% | ▲ Add | 3 | SEC ↗ |
| 30 | Capital Research Global Investors | 17.32M | — | $7.85B | 1.4% | n/c | 1 | SEC ↗ |
| 31 | State Street Global Advisors ✦ (passive) | 11.69M | +0.7% | $5.30B | 0.2% | ▲ Add | 5 | SEC ↗ |
| 32 | Invesco Ltd. | 7.85M | — | $3.56B | 0.3% | n/c | 1 | SEC ↗ |
| 33 | Invesco Ltd. | 7.85M | — | $3.56B | 0.3% | n/c | 1 | SEC ↗ |
| 34 | Invesco Ltd. | 7.85M | — | $3.56B | 0.3% | n/c | 1 | SEC ↗ |
| 35 | Invesco Ltd. | 7.85M | — | $3.56B | 0.3% | n/c | 1 | SEC ↗ |
| 36 | Invesco Ltd. | 7.85M | — | $3.56B | 0.3% | n/c | 1 | SEC ↗ |
| 37 | Invesco Ltd. | 7.85M | — | $3.56B | 0.3% | n/c | 1 | SEC ↗ |
| 38 | Invesco Ltd. | 7.85M | — | $3.56B | 0.3% | n/c | 1 | SEC ↗ |
| 39 | Invesco Ltd. | 7.85M | — | $3.56B | 0.3% | n/c | 1 | SEC ↗ |
| 40 | Invesco Ltd. | 7.85M | — | $3.56B | 0.3% | n/c | 1 | SEC ↗ |
| 41 | Invesco Ltd. | 7.85M | — | $3.56B | 0.3% | n/c | 1 | SEC ↗ |
| 42 | Invesco Ltd. | 7.85M | — | $3.56B | 0.3% | n/c | 1 | SEC ↗ |
| 43 | Invesco Ltd. | 7.85M | — | $3.56B | 0.3% | n/c | 1 | SEC ↗ |
| 44 | Invesco Ltd. | 7.85M | — | $3.56B | 0.3% | n/c | 1 | SEC ↗ |
| 45 | Invesco Ltd. | 7.85M | — | $3.56B | 0.3% | n/c | 1 | SEC ↗ |
| 46 | Invesco Ltd. | 7.85M | — | $3.56B | 0.3% | n/c | 1 | SEC ↗ |
| 47 | Invesco Ltd. | 7.85M | — | $3.56B | 0.3% | n/c | 1 | SEC ↗ |
| 48 | Invesco Ltd. | 7.85M | — | $3.56B | 0.3% | n/c | 1 | SEC ↗ |
| 49 | JPMorgan Chase ✦ | 6.04M | -53.1% | $2.74B | 0.2% | ▼ Trim | 2 | SEC ↗ |
| 50 | JPMorgan Chase ✦ | 6.04M | -53.1% | $2.74B | 0.2% | ▼ Trim | 2 | SEC ↗ |
| 51 | JPMorgan Chase ✦ | 6.04M | -53.1% | $2.74B | 0.2% | ▼ Trim | 2 | SEC ↗ |
| 52 | JPMorgan Chase ✦ | 6.04M | -53.1% | $2.74B | 0.2% | ▼ Trim | 2 | SEC ↗ |
| 53 | JPMorgan Chase ✦ | 6.04M | -53.1% | $2.74B | 0.2% | ▼ Trim | 2 | SEC ↗ |
| 54 | JPMorgan Chase ✦ | 6.04M | -53.1% | $2.74B | 0.2% | ▼ Trim | 2 | SEC ↗ |
| 55 | JPMorgan Chase ✦ | 6.04M | -53.1% | $2.74B | 0.2% | ▼ Trim | 2 | SEC ↗ |
| 56 | JPMorgan Chase ✦ | 6.04M | -53.1% | $2.74B | 0.2% | ▼ Trim | 2 | SEC ↗ |
| 57 | JPMorgan Chase ✦ | 6.04M | -53.1% | $2.74B | 0.2% | ▼ Trim | 2 | SEC ↗ |
| 58 | JPMorgan Chase ✦ | 6.04M | -53.1% | $2.74B | 0.2% | ▼ Trim | 2 | SEC ↗ |
| 59 | JPMorgan Chase ✦ | 6.04M | -53.1% | $2.74B | 0.2% | ▼ Trim | 2 | SEC ↗ |
| 60 | JPMorgan Chase ✦ | 6.04M | -53.1% | $2.74B | 0.2% | ▼ Trim | 2 | SEC ↗ |
| 61 | JPMorgan Chase ✦ | 6.04M | -53.1% | $2.74B | 0.2% | ▼ Trim | 2 | SEC ↗ |
| 62 | JPMorgan Chase ✦ | 6.04M | -53.1% | $2.74B | 0.2% | ▼ Trim | 2 | SEC ↗ |
| 63 | JPMorgan Chase ✦ | 6.04M | -53.1% | $2.74B | 0.2% | ▼ Trim | 2 | SEC ↗ |
| 64 | JPMorgan Chase ✦ | 6.04M | -53.1% | $2.74B | 0.2% | ▼ Trim | 2 | SEC ↗ |
| 65 | JPMorgan Chase ✦ | 6.04M | -53.1% | $2.74B | 0.2% | ▼ Trim | 2 | SEC ↗ |
| 66 | JPMorgan Chase ✦ | 6.04M | -53.1% | $2.74B | 0.2% | ▼ Trim | 2 | SEC ↗ |
| 67 | JPMorgan Chase ✦ | 6.04M | -53.1% | $2.74B | 0.2% | ▼ Trim | 2 | SEC ↗ |
| 68 | JPMorgan Chase ✦ | 6.04M | -53.1% | $2.74B | 0.2% | ▼ Trim | 2 | SEC ↗ |
| 69 | Geode Capital Management ✦ (passive) | 5.98M | +0.1% | $2.70B | 0.2% | ▲ Add | 7 | SEC ↗ |
| 70 | Geode Capital Management ✦ (passive) | 5.98M | +0.1% | $2.70B | 0.2% | ▲ Add | 7 | SEC ↗ |
| 71 | Capital International Investors | 4.73M | — | $2.15B | 0.3% | n/c | 1 | SEC ↗ |
| 72 | Alliancebernstein L.P. | 4.50M | — | $2.04B | 0.6% | n/c | 1 | SEC ↗ |
| 73 | Loomis Sayles & Co L P | 4.03M | — | $1.83B | 2.2% | n/c | 1 | SEC ↗ |
| 74 | Loomis Sayles & Co L P | 4.03M | — | $1.83B | 2.2% | n/c | 1 | SEC ↗ |
| 75 | Wellington Management ✦ | 3.82M | -19.9% | $1.73B | 0.3% | ▼ Trim | 7 | SEC ↗ |
| 76 | Wellington Management ✦ | 3.82M | -19.9% | $1.73B | 0.3% | ▼ Trim | 7 | SEC ↗ |
| 77 | Wellington Management ✦ | 3.82M | -19.9% | $1.73B | 0.3% | ▼ Trim | 7 | SEC ↗ |
| 78 | Wellington Management ✦ | 3.82M | -19.9% | $1.73B | 0.3% | ▼ Trim | 7 | SEC ↗ |
| 79 | Wellington Management ✦ | 3.82M | -19.9% | $1.73B | 0.3% | ▼ Trim | 7 | SEC ↗ |
| 80 | Wellington Management ✦ | 3.82M | -19.9% | $1.73B | 0.3% | ▼ Trim | 7 | SEC ↗ |
| 81 | Wellington Management ✦ | 3.82M | -19.9% | $1.73B | 0.3% | ▼ Trim | 7 | SEC ↗ |
| 82 | Wellington Management ✦ | 3.82M | -19.9% | $1.73B | 0.3% | ▼ Trim | 7 | SEC ↗ |
| 83 | Victory Capital Management Inc | 3.36M | — | $1.52B | 0.9% | n/c | 1 | SEC ↗ |
| 84 | Jennison Associates Llc | 3.25M | — | $1.47B | 0.9% | n/c | 1 | SEC ↗ |
| 85 | Jennison Associates Llc | 3.25M | — | $1.47B | 0.9% | n/c | 1 | SEC ↗ |
| 86 | Norges Bank ✦ (passive) | 3.18M | New | $1.44B | 0.2% | New | 1 | SEC ↗ |
| 87 | Morgan Stanley ✦ | 3.12M | +0.4% | $1.41B | 0.1% | ▲ Add | 2 | SEC ↗ |
| 88 | Morgan Stanley ✦ | 3.12M | +0.4% | $1.41B | 0.1% | ▲ Add | 2 | SEC ↗ |
| 89 | Morgan Stanley ✦ | 3.12M | +0.4% | $1.41B | 0.1% | ▲ Add | 2 | SEC ↗ |
| 90 | Morgan Stanley ✦ | 3.12M | +0.4% | $1.41B | 0.1% | ▲ Add | 2 | SEC ↗ |
| 91 | Morgan Stanley ✦ | 3.12M | +0.4% | $1.41B | 0.1% | ▲ Add | 2 | SEC ↗ |
| 92 | Morgan Stanley ✦ | 3.12M | +0.4% | $1.41B | 0.1% | ▲ Add | 2 | SEC ↗ |
| 93 | Morgan Stanley ✦ | 3.12M | +0.4% | $1.41B | 0.1% | ▲ Add | 2 | SEC ↗ |
| 94 | Morgan Stanley ✦ | 3.12M | +0.4% | $1.41B | 0.1% | ▲ Add | 2 | SEC ↗ |
| 95 | Morgan Stanley ✦ | 3.12M | +0.4% | $1.41B | 0.1% | ▲ Add | 2 | SEC ↗ |
| 96 | Morgan Stanley ✦ | 3.12M | +0.4% | $1.41B | 0.1% | ▲ Add | 2 | SEC ↗ |
| 97 | Morgan Stanley ✦ | 3.12M | +0.4% | $1.41B | 0.1% | ▲ Add | 2 | SEC ↗ |
| 98 | Morgan Stanley ✦ | 3.12M | +0.4% | $1.41B | 0.1% | ▲ Add | 2 | SEC ↗ |
| 99 | Morgan Stanley ✦ | 3.12M | +0.4% | $1.41B | 0.1% | ▲ Add | 2 | SEC ↗ |
| 100 | Morgan Stanley ✦ | 3.12M | +0.4% | $1.41B | 0.1% | ▲ Add | 2 | SEC ↗ |
“Their weight” = the position's share of that manager's reported 13F equity value — the conviction measure. ✦ = curated manager.
New buyers
| Norges Bank | $1.44B | 0.2% |
Exited
| D. E. Shaw & Co. | $1.31M | was 0.0% |
| GAMCO Investors | $200,520 | was 0.0% |
Full-market context: across ALL 13F filers (SEC structured data, Q1 2026): 1,678 holders, 225.07M shares, $98.10B reported. This is a different, older period than the tracked-universe figures above and the two are never mixed.
Frequently co-owned
What else this security's tracked holders most often hold — shared-ownership counts, not fundamental relationships.
Provenance: Ownership from parsed 13F common-stock positions (tracked universe, comparable sets for changes); insider rows from Forms 3/4/5; stakes from Schedules 13D/13G; every filing links to its original on SEC EDGAR.
Reporting period: Q4 2025 ·
Methodology ·
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