Security record · archived quarter
TYRA
Tyra Biosciences, Inc. · Healthcare · Biotechnology
61Tracked holders
-1Δ holders
13.06MShares held
$343.28MReported value
+1New positions
−2Exits
Momentum inputs (comparable managers):
holder breadth -1.6% ·
share flow +6.6% ·
net new positions -1.6%
· formula
Concentrated accumulation: rising shares among fewer holders
All ownership figures: tracked 13F managers only, common-stock positions, reporting period Q4 2025
Ownership over time
| Quarter | Holders | Δ | Shares | Reported value | New | Exits |
|---|---|---|---|---|---|---|
| Q2 2026 | 69 | +1 | 26.24M | $838.62M | +9 | −8 |
| Q1 2026 | 71 | +10 | 23.52M | $900.04M | +12 | −2 |
| Q4 2025 | 61 | -1 | 13.06M | $343.28M | +1 | −2 |
| Q3 2025 | 17 | 0 | 6.63M | $92.78M | n/a | n/a |
| Q2 2025 | 14 | +2 | 5.95M | $56.99M | +2 | n/a |
| Q1 2025 | 9 | -1 | 2.08M | $19.36M | n/a | −1 |
| Q4 2024 | 10 | +1 | 1.73M | $24.09M | +2 | −1 |
| Q3 2024 | 8 | +5 | 939.26K | $22.08M | +5 | n/a |
| Q2 2024 | 3 | n/a | 674.98K | $10.79M | n/a | n/a |
Who holds it · Q4 2025
| # | Manager | Shares | Δ shares | Value | Their weight | Held | ||
|---|---|---|---|---|---|---|---|---|
| 1 | Janus Henderson Group Plc | 2.94M | n/a | $77.08M | 0.0% | n/c | 1 | SEC ↗ |
| 2 | BlackRock ✦ (passive) | 2.09M | +11.6% | $54.85M | 0.0% | ▲ Add | 3 | SEC ↗ ×9 |
| 3 | The Vanguard Group ✦ (passive) | 1.57M | +3.5% | $41.35M | 0.0% | ▲ Add | 3 | SEC ↗ ×3 |
| 4 | Point72 Asset Management ✦ | 874.19K | +210.0% | $22.98M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 5 | Balyasny Asset Management L.P. | 818.33K | n/a | $21.51M | 0.0% | n/c | 1 | SEC ↗ |
| 6 | State Street Global Advisors ✦ (passive) | 749.46K | +74.9% | $19.70M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 7 | Marshall Wace ✦ | 711.89K | +18.2% | $18.72M | 0.0% | ▲ Add | 6 | SEC ↗ ×2 |
| 8 | Geode Capital Management ✦ (passive) | 657.76K | +10.1% | $17.30M | 0.0% | ▲ Add | 7 | SEC ↗ ×2 |
| 9 | Northern Trust Corp | 200.96K | n/a | $5.28M | 0.0% | n/c | 1 | SEC ↗ ×4 |
| 10 | Charles Schwab Investment… | 199.43K | n/a | $5.24M | 0.0% | n/c | 1 | SEC ↗ |
| 11 | Goldman Sachs Group ✦ | 182.39K | +82.1% | $4.79M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 12 | Raymond James Financial Inc | 170.03K | n/a | $4.47M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 13 | BNP Paribas Asset Management… | 129.78K | n/a | $3.41M | 0.0% | n/c | 1 | SEC ↗ |
| 14 | Invesco Ltd. | 129.44K | n/a | $3.40M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 15 | Bnp Paribas Financial Markets | 120.28K | n/a | $3.16M | 0.0% | n/c | 1 | SEC ↗ |
| 16 | Morgan Stanley ✦ | 118.90K | -63.1% | $3.13M | 0.0% | ▼ Trim | 2 | SEC ↗ ×6 |
| 17 | Millennium Management ✦ | 114.39K | -20.6% | $3.01M | 0.0% | ▼ Trim | 6 | SEC ↗ |
| 18 | Two Sigma Investments ✦ | 107.02K | -46.3% | $2.81M | 0.0% | ▼ Trim | 7 | SEC ↗ |
| 19 | Wellington Management ✦ | 104.31K | +25.9% | $2.74M | 0.0% | ▲ Add | 7 | SEC ↗ ×3 |
| 20 | Dimensional Fund Advisors Lp | 95.64K | n/a | $2.51M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 21 | Barclays Plc | 76.31K | n/a | $2.01M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 22 | JPMorgan Chase ✦ | 71.17K | -52.1% | $1.87M | 0.0% | ▼ Trim | 2 | SEC ↗ ×3 |
| 23 | Bank of New York Mellon Corp | 60.90K | n/a | $1.60M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 24 | UBS Group AG | 58.86K | n/a | $1.55M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 25 | Susquehanna International Group, Llp | 55.13K | n/a | $1.45M | 0.0% | n/c | 1 | SEC ↗ |
| 26 | Ameriprise Financial Inc | 54.62K | n/a | $1.44M | 0.0% | n/c | 1 | SEC ↗ |
| 27 | Squarepoint Ops LLC | 54.42K | n/a | $1.43M | 0.0% | n/c | 1 | SEC ↗ |
| 28 | Nuveen, LLC | 47.35K | n/a | $1.24M | 0.0% | n/c | 1 | SEC ↗ |
| 29 | American Century Companies Inc | 46.23K | n/a | $1.22M | 0.0% | n/c | 1 | SEC ↗ |
| 30 | State Of Wisconsin Investment Board | 39.02K | n/a | $1.03M | 0.0% | n/c | 1 | SEC ↗ |
| 31 | Rhumbline Advisers | 38.79K | n/a | $1.02M | 0.0% | n/c | 1 | SEC ↗ |
| 32 | Bank Of America Corp /De/ | 38.31K | n/a | $1.01M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 33 | Alliancebernstein L.P. | 31.99K | n/a | $841,017 | 0.0% | n/c | 1 | SEC ↗ |
| 34 | Voya Investment Management Llc | 29.89K | n/a | $785,729 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 35 | Wells Fargo & Company/Mn | 29.05K | n/a | $763,698 | 0.0% | n/c | 1 | SEC ↗ |
| 36 | Canada Pension Plan Investment Board | 28.90K | n/a | $759,781 | 0.0% | n/c | 1 | SEC ↗ |
| 37 | Fisher Asset Management ✦ | 28.80K | New | $757,152 | 0.0% | New | 1 | SEC ↗ |
| 38 | AQR Capital Management ✦ | 28.63K | +2.0% | $752,707 | 0.0% | ▲ Add | 3 | SEC ↗ ×6 |
| 39 | Creative Planning | 19.60K | n/a | $515,363 | 0.0% | n/c | 1 | SEC ↗ |
| 40 | Victory Capital Management Inc | 18.79K | n/a | $493,989 | 0.0% | n/c | 1 | SEC ↗ |
| 41 | Deutsche Bank Ag\ | 16.38K | n/a | $430,551 | 0.0% | n/c | 1 | SEC ↗ |
| 42 | T. Rowe Price ✦ | 14.43K | +12.7% | $380,000 | 0.0% | ▲ Add | 3 | SEC ↗ |
| 43 | Russell Investments Group, Ltd. | 13.00K | n/a | $341,664 | 0.0% | n/c | 1 | SEC ↗ ×5 |
| 44 | Franklin Resources Inc | 12.97K | n/a | $340,981 | 0.0% | n/c | 1 | SEC ↗ |
| 45 | MIRAE ASSET GLOBAL ETFS HOLDINGS… | 12.91K | n/a | $338,585 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 46 | Fidelity (FMR) ✦ | 12.56K | +0.3% | $330,280 | 0.0% | ▲ Add | 3 | SEC ↗ ×2 |
| 47 | Bank Of Nova Scotia | 11.10K | n/a | $291,819 | 0.0% | n/c | 1 | SEC ↗ |
| 48 | Manufacturers Life Insurance… | 8.36K | n/a | $219,706 | 0.0% | n/c | 1 | SEC ↗ |
| 49 | New York State Common Retirement… | 7.42K | n/a | $195,151 | 0.0% | n/c | 1 | SEC ↗ |
| 50 | Citigroup Inc | 3.82K | n/a | $100,349 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 51 | Mirae Asset Global Investments Co.… | 2.59K | n/a | $68,196 | 0.0% | n/c | 1 | SEC ↗ |
| 52 | Legal & General Group Plc | 2.37K | n/a | $62,228 | 0.0% | n/c | 1 | SEC ↗ |
| 53 | California State Teachers… | 1.59K | n/a | $41,933 | 0.0% | n/c | 1 | SEC ↗ |
| 54 | Cwm, Llc | 1.55K | n/a | $41,000 | 0.0% | n/c | 1 | SEC ↗ |
| 55 | Federated Hermes, Inc. | 1.30K | n/a | $34,098 | 0.0% | n/c | 1 | SEC ↗ |
| 56 | Osaic Holdings, Inc. | 1.19K | n/a | $31,232 | 0.0% | n/c | 1 | SEC ↗ |
| 57 | Royal Bank Of Canada | 742 | n/a | $19,000 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 58 | Pnc Financial Services Group, Inc. | 208 | n/a | $5,469 | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 59 | Daiwa Securities Group Inc. | 173 | n/a | $5,000 | 0.0% | n/c | 1 | SEC ↗ |
| 60 | Optiver Holding B.V. | 128 | n/a | $3,365 | 0.0% | n/c | 1 | SEC ↗ |
| 61 | Rockefeller Capital Management L.P. | 84 | n/a | $2,208 | 0.0% | n/c | 1 | SEC ↗ |
“Their weight” = the position's share of that manager's reported 13F equity value: the conviction measure. ✦ = curated manager.
New buyers
| Fisher Asset Management | $757,152 | 0.0% |
Exited
| Renaissance Technologies | $2.38M | was 0.0% |
| Citadel Advisors | $1.56M | was 0.0% |
Full-market context: across ALL 13F filers (SEC structured data, Q1 2026): 163 holders, 65.87M shares, $2.48B reported. This is a different, older period than the tracked-universe figures above and the two are never mixed.
Frequently co-owned
What else this security's tracked holders most often hold: shared-ownership counts, not fundamental relationships.
Open-market purchases (P)
Sep 09
Verjee Rehan
Director · 972 sh @ 20.58 · $20,000
Open-market sales (S)
No open-market insider sales in our coverage window.
Awards, exercises and tax withholding are never counted as buys or sales here. Methodology
Sep 21
SC 13G: BIOTECHNOLOGY VALUE FUND L P
Sep 17
SC 13D/A: RA CAPITAL MANAGEMENT, L.P.
19.9% of class · View original SEC filing ↗
Sep 17
SC 13G: Paradigm Biocapital Advisors LP
Aug 14
SC 13G/A: FARALLON CAPITAL MANAGEMENT, L.L.C.
Aug 14
SC 13G/A: NEXTECH VI ONCOLOGY SCSP
Jul 30
SC 13G: BlackRock, Inc.
Provenance: Ownership from parsed 13F common-stock positions (tracked universe, comparable sets for changes); insider rows from Forms 3/4/5; stakes from Schedules 13D/13G; every filing links to its original on SEC EDGAR.
Reporting period: Q4 2025 ·
Methodology ·
Get this via the API