Security record · archived quarter
TYRA
Tyra Biosciences, Inc. · Healthcare · Biotechnology
61Tracked holders
-1Δ holders
13.06MShares held
$343.28MReported value
+1New positions
−2Exits
Momentum inputs (comparable managers):
holder breadth -1.6% ·
share flow +6.6% ·
net new positions -1.6%
— formula
Concentrated accumulation — rising shares among fewer holders
All ownership figures: tracked 13F managers only, common-stock positions, reporting period Q4 2025
Ownership over time
| Quarter | Holders | Δ | Shares | Reported value | New | Exits |
|---|---|---|---|---|---|---|
| Q2 2026 | 70 | +2 | 26.25M | $838.89M | +9 | −7 |
| Q1 2026 | 71 | +10 | 23.52M | $900.04M | +12 | −2 |
| Q4 2025 | 61 | -1 | 13.06M | $343.28M | +1 | −2 |
| Q3 2025 | 17 | 0 | 6.63M | $92.78M | — | — |
| Q2 2025 | 14 | +2 | 5.95M | $56.99M | +2 | — |
| Q1 2025 | 9 | -1 | 2.08M | $19.36M | — | −1 |
| Q4 2024 | 10 | +1 | 1.73M | $24.09M | +2 | −1 |
| Q3 2024 | 8 | +5 | 939.26K | $22.08M | +5 | — |
| Q2 2024 | 3 | — | 674.98K | $10.79M | — | — |
Who holds it · Q4 2025
| # | Manager | Shares | Δ shares | Value | Their weight | Held | ||
|---|---|---|---|---|---|---|---|---|
| 1 | Janus Henderson Group Plc | 2.94M | — | $77.08M | 0.0% | n/c | 1 | SEC ↗ |
| 2 | BlackRock ✦ (passive) | 2.09M | +11.6% | $54.85M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 3 | BlackRock ✦ (passive) | 2.09M | +11.6% | $54.85M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 4 | BlackRock ✦ (passive) | 2.09M | +11.6% | $54.85M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 5 | BlackRock ✦ (passive) | 2.09M | +11.6% | $54.85M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 6 | BlackRock ✦ (passive) | 2.09M | +11.6% | $54.85M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 7 | BlackRock ✦ (passive) | 2.09M | +11.6% | $54.85M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 8 | BlackRock ✦ (passive) | 2.09M | +11.6% | $54.85M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 9 | BlackRock ✦ (passive) | 2.09M | +11.6% | $54.85M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 10 | BlackRock ✦ (passive) | 2.09M | +11.6% | $54.85M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 11 | The Vanguard Group ✦ (passive) | 1.57M | +3.5% | $41.35M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 12 | The Vanguard Group ✦ (passive) | 1.57M | +3.5% | $41.35M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 13 | The Vanguard Group ✦ (passive) | 1.57M | +3.5% | $41.35M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 14 | Point72 Asset Management ✦ | 874.19K | +210.0% | $22.98M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 15 | Balyasny Asset Management L.P. | 818.33K | — | $21.51M | 0.0% | n/c | 1 | SEC ↗ |
| 16 | State Street Global Advisors ✦ (passive) | 749.46K | +74.9% | $19.70M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 17 | Marshall Wace ✦ | 711.89K | +18.2% | $18.72M | 0.0% | ▲ Add | 6 | SEC ↗ |
| 18 | Marshall Wace ✦ | 711.89K | +18.2% | $18.72M | 0.0% | ▲ Add | 6 | SEC ↗ |
| 19 | Geode Capital Management ✦ (passive) | 657.76K | +10.1% | $17.30M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 20 | Geode Capital Management ✦ (passive) | 657.76K | +10.1% | $17.30M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 21 | Northern Trust Corp | 200.96K | — | $5.28M | 0.0% | n/c | 1 | SEC ↗ |
| 22 | Northern Trust Corp | 200.96K | — | $5.28M | 0.0% | n/c | 1 | SEC ↗ |
| 23 | Northern Trust Corp | 200.96K | — | $5.28M | 0.0% | n/c | 1 | SEC ↗ |
| 24 | Northern Trust Corp | 200.96K | — | $5.28M | 0.0% | n/c | 1 | SEC ↗ |
| 25 | Charles Schwab Investment… | 199.43K | — | $5.24M | 0.0% | n/c | 1 | SEC ↗ |
| 26 | Goldman Sachs Group ✦ | 182.39K | +82.1% | $4.79M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 27 | Raymond James Financial Inc | 170.03K | — | $4.47M | 0.0% | n/c | 1 | SEC ↗ |
| 28 | Raymond James Financial Inc | 170.03K | — | $4.47M | 0.0% | n/c | 1 | SEC ↗ |
| 29 | Raymond James Financial Inc | 170.03K | — | $4.47M | 0.0% | n/c | 1 | SEC ↗ |
| 30 | BNP Paribas Asset Management… | 129.78K | — | $3.41M | 0.0% | n/c | 1 | SEC ↗ |
| 31 | Invesco Ltd. | 129.44K | — | $3.40M | 0.0% | n/c | 1 | SEC ↗ |
| 32 | Invesco Ltd. | 129.44K | — | $3.40M | 0.0% | n/c | 1 | SEC ↗ |
| 33 | Invesco Ltd. | 129.44K | — | $3.40M | 0.0% | n/c | 1 | SEC ↗ |
| 34 | Bnp Paribas Financial Markets | 120.28K | — | $3.16M | 0.0% | n/c | 1 | SEC ↗ |
| 35 | Morgan Stanley ✦ | 118.90K | -63.1% | $3.13M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 36 | Morgan Stanley ✦ | 118.90K | -63.1% | $3.13M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 37 | Morgan Stanley ✦ | 118.90K | -63.1% | $3.13M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 38 | Morgan Stanley ✦ | 118.90K | -63.1% | $3.13M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 39 | Morgan Stanley ✦ | 118.90K | -63.1% | $3.13M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 40 | Morgan Stanley ✦ | 118.90K | -63.1% | $3.13M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 41 | Millennium Management ✦ | 114.39K | -20.6% | $3.01M | 0.0% | ▼ Trim | 6 | SEC ↗ |
| 42 | Two Sigma Investments ✦ | 107.02K | -46.3% | $2.81M | 0.0% | ▼ Trim | 7 | SEC ↗ |
| 43 | Wellington Management ✦ | 104.31K | +25.9% | $2.74M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 44 | Wellington Management ✦ | 104.31K | +25.9% | $2.74M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 45 | Wellington Management ✦ | 104.31K | +25.9% | $2.74M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 46 | Dimensional Fund Advisors Lp | 95.64K | — | $2.51M | 0.0% | n/c | 1 | SEC ↗ |
| 47 | Dimensional Fund Advisors Lp | 95.64K | — | $2.51M | 0.0% | n/c | 1 | SEC ↗ |
| 48 | Barclays Plc | 76.31K | — | $2.01M | 0.0% | n/c | 1 | SEC ↗ |
| 49 | Barclays Plc | 76.31K | — | $2.01M | 0.0% | n/c | 1 | SEC ↗ |
| 50 | JPMorgan Chase ✦ | 71.17K | -52.1% | $1.87M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 51 | JPMorgan Chase ✦ | 71.17K | -52.1% | $1.87M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 52 | JPMorgan Chase ✦ | 71.17K | -52.1% | $1.87M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 53 | Bank of New York Mellon Corp | 60.90K | — | $1.60M | 0.0% | n/c | 1 | SEC ↗ |
| 54 | Bank of New York Mellon Corp | 60.90K | — | $1.60M | 0.0% | n/c | 1 | SEC ↗ |
| 55 | UBS Group AG | 58.86K | — | $1.55M | 0.0% | n/c | 1 | SEC ↗ |
| 56 | UBS Group AG | 58.86K | — | $1.55M | 0.0% | n/c | 1 | SEC ↗ |
| 57 | UBS Group AG | 58.86K | — | $1.55M | 0.0% | n/c | 1 | SEC ↗ |
| 58 | Susquehanna International Group, Llp | 55.13K | — | $1.45M | 0.0% | n/c | 1 | SEC ↗ |
| 59 | Ameriprise Financial Inc | 54.62K | — | $1.44M | 0.0% | n/c | 1 | SEC ↗ |
| 60 | Squarepoint Ops LLC | 54.42K | — | $1.43M | 0.0% | n/c | 1 | SEC ↗ |
| 61 | Nuveen, LLC | 47.35K | — | $1.24M | 0.0% | n/c | 1 | SEC ↗ |
| 62 | American Century Companies Inc | 46.23K | — | $1.22M | 0.0% | n/c | 1 | SEC ↗ |
| 63 | State Of Wisconsin Investment Board | 39.02K | — | $1.03M | 0.0% | n/c | 1 | SEC ↗ |
| 64 | Rhumbline Advisers | 38.79K | — | $1.02M | 0.0% | n/c | 1 | SEC ↗ |
| 65 | Bank Of America Corp /De/ | 38.31K | — | $1.01M | 0.0% | n/c | 1 | SEC ↗ |
| 66 | Bank Of America Corp /De/ | 38.31K | — | $1.01M | 0.0% | n/c | 1 | SEC ↗ |
| 67 | Bank Of America Corp /De/ | 38.31K | — | $1.01M | 0.0% | n/c | 1 | SEC ↗ |
| 68 | Alliancebernstein L.P. | 31.99K | — | $841,017 | 0.0% | n/c | 1 | SEC ↗ |
| 69 | Voya Investment Management Llc | 29.89K | — | $785,729 | 0.0% | n/c | 1 | SEC ↗ |
| 70 | Voya Investment Management Llc | 29.89K | — | $785,729 | 0.0% | n/c | 1 | SEC ↗ |
| 71 | Wells Fargo & Company/Mn | 29.05K | — | $763,698 | 0.0% | n/c | 1 | SEC ↗ |
| 72 | Canada Pension Plan Investment Board | 28.90K | — | $759,781 | 0.0% | n/c | 1 | SEC ↗ |
| 73 | Fisher Asset Management ✦ | 28.80K | New | $757,152 | 0.0% | New | 1 | SEC ↗ |
| 74 | AQR Capital Management ✦ | 28.63K | +2.0% | $752,707 | 0.0% | ▲ Add | 3 | SEC ↗ |
| 75 | AQR Capital Management ✦ | 28.63K | +2.0% | $752,707 | 0.0% | ▲ Add | 3 | SEC ↗ |
| 76 | AQR Capital Management ✦ | 28.63K | +2.0% | $752,707 | 0.0% | ▲ Add | 3 | SEC ↗ |
| 77 | AQR Capital Management ✦ | 28.63K | +2.0% | $752,707 | 0.0% | ▲ Add | 3 | SEC ↗ |
| 78 | AQR Capital Management ✦ | 28.63K | +2.0% | $752,707 | 0.0% | ▲ Add | 3 | SEC ↗ |
| 79 | AQR Capital Management ✦ | 28.63K | +2.0% | $752,707 | 0.0% | ▲ Add | 3 | SEC ↗ |
| 80 | Creative Planning | 19.60K | — | $515,363 | 0.0% | n/c | 1 | SEC ↗ |
| 81 | Victory Capital Management Inc | 18.79K | — | $493,989 | 0.0% | n/c | 1 | SEC ↗ |
| 82 | Deutsche Bank Ag\ | 16.38K | — | $430,551 | 0.0% | n/c | 1 | SEC ↗ |
| 83 | T. Rowe Price ✦ | 14.43K | +12.7% | $380,000 | 0.0% | ▲ Add | 3 | SEC ↗ |
| 84 | Russell Investments Group, Ltd. | 13.00K | — | $341,664 | 0.0% | n/c | 1 | SEC ↗ |
| 85 | Russell Investments Group, Ltd. | 13.00K | — | $341,664 | 0.0% | n/c | 1 | SEC ↗ |
| 86 | Russell Investments Group, Ltd. | 13.00K | — | $341,664 | 0.0% | n/c | 1 | SEC ↗ |
| 87 | Russell Investments Group, Ltd. | 13.00K | — | $341,664 | 0.0% | n/c | 1 | SEC ↗ |
| 88 | Russell Investments Group, Ltd. | 13.00K | — | $341,664 | 0.0% | n/c | 1 | SEC ↗ |
| 89 | Franklin Resources Inc | 12.97K | — | $340,981 | 0.0% | n/c | 1 | SEC ↗ |
| 90 | MIRAE ASSET GLOBAL ETFS HOLDINGS… | 12.91K | — | $338,585 | 0.0% | n/c | 1 | SEC ↗ |
| 91 | MIRAE ASSET GLOBAL ETFS HOLDINGS… | 12.91K | — | $338,585 | 0.0% | n/c | 1 | SEC ↗ |
| 92 | Fidelity (FMR) ✦ | 12.56K | +0.3% | $330,280 | 0.0% | ▲ Add | 3 | SEC ↗ |
| 93 | Fidelity (FMR) ✦ | 12.56K | +0.3% | $330,280 | 0.0% | ▲ Add | 3 | SEC ↗ |
| 94 | Bank Of Nova Scotia | 11.10K | — | $291,819 | 0.0% | n/c | 1 | SEC ↗ |
| 95 | Manufacturers Life Insurance… | 8.36K | — | $219,706 | 0.0% | n/c | 1 | SEC ↗ |
| 96 | New York State Common Retirement… | 7.42K | — | $195,151 | 0.0% | n/c | 1 | SEC ↗ |
| 97 | Citigroup Inc | 3.82K | — | $100,349 | 0.0% | n/c | 1 | SEC ↗ |
| 98 | Citigroup Inc | 3.82K | — | $100,349 | 0.0% | n/c | 1 | SEC ↗ |
| 99 | Mirae Asset Global Investments Co.… | 2.59K | — | $68,196 | 0.0% | n/c | 1 | SEC ↗ |
| 100 | Legal & General Group Plc | 2.37K | — | $62,228 | 0.0% | n/c | 1 | SEC ↗ |
“Their weight” = the position's share of that manager's reported 13F equity value — the conviction measure. ✦ = curated manager.
New buyers
| Fisher Asset Management | $757,152 | 0.0% |
Exited
| Renaissance Technologies | $2.38M | was 0.0% |
| Citadel Advisors | $1.56M | was 0.0% |
Full-market context: across ALL 13F filers (SEC structured data, Q1 2026): 163 holders, 65.87M shares, $2.48B reported. This is a different, older period than the tracked-universe figures above and the two are never mixed.
Frequently co-owned
What else this security's tracked holders most often hold — shared-ownership counts, not fundamental relationships.
Provenance: Ownership from parsed 13F common-stock positions (tracked universe, comparable sets for changes); insider rows from Forms 3/4/5; stakes from Schedules 13D/13G; every filing links to its original on SEC EDGAR.
Reporting period: Q4 2025 ·
Methodology ·
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