TYRA
Tyra Biosciences, Inc. · Healthcare · Biotechnology
Momentum inputs (comparable managers):
holder breadth +1.5% ·
share flow +30.0% ·
net new positions +1.4%
— formula
Broad accumulation — rising shares across more holders
All ownership figures: tracked 13F managers only, common-stock positions, reporting period Q2 2026
| Quarter | Holders | Δ | Shares | Reported value | New | Exits |
|---|---|---|---|---|---|---|
| Q2 2026 | 69 | +1 | 26.24M | $838.62M | +9 | −8 |
| Q1 2026 | 71 | +10 | 23.52M | $900.04M | +12 | −2 |
| Q4 2025 | 61 | -1 | 13.06M | $343.28M | +1 | −2 |
| Q3 2025 | 17 | 0 | 6.63M | $92.78M | — | — |
| Q2 2025 | 14 | +2 | 5.95M | $56.99M | +2 | — |
| Q1 2025 | 9 | -1 | 2.08M | $19.36M | — | −1 |
| Q4 2024 | 10 | +1 | 1.73M | $24.09M | +2 | −1 |
| Q3 2024 | 8 | +5 | 939.26K | $22.08M | +5 | — |
| Q2 2024 | 3 | — | 674.98K | $10.79M | — | — |
| # | Manager | Shares | Δ shares | Value | Their weight | Held | ||
|---|---|---|---|---|---|---|---|---|
| 1 | Fidelity (FMR) ✦ | 8.92M | +15.1% | $284.92M | 0.0% | ▲ Add | 5 | SEC ↗ ×5 |
| 2 | BlackRock ✦ (passive) | 3.03M | +36.7% | $96.84M | 0.0% | ▲ Add | 5 | SEC ↗ ×11 |
| 3 | T. Rowe Price ✦ | 2.78M | +182.2% | $88.88M | 0.0% | ▲ Add | 5 | SEC ↗ ×2 |
| 4 | State Street Global Advisors ✦ (passive) | 2.14M | +76.0% | $68.36M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 5 | Vanguard Capital Management Llc | 1.51M | +34.0% | $48.18M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 6 | Geode Capital Management ✦ (passive) | 970.73K | +47.4% | $31.01M | 0.0% | ▲ Add | 9 | SEC ↗ ×2 |
| 7 | Marshall Wace ✦ | 583.13K | +194.9% | $18.63M | 0.0% | ▲ Add | 8 | SEC ↗ |
| 8 | Goldman Sachs Group ✦ | 463.48K | -15.8% | $14.80M | 0.0% | ▼ Trim | 4 | SEC ↗ ×2 |
| 9 | Jennison Associates Llc | 450.96K | -28.7% | $14.40M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 10 | Two Sigma Investments ✦ | 449.81K | +342.6% | $14.37M | 0.0% | ▲ Add | 9 | SEC ↗ |
| 11 | Bank Of America Corp /De/ | 349.73K | +66.6% | $11.17M | 0.0% | ▲ Add | 3 | SEC ↗ ×3 |
| 12 | Northern Trust Corp | 310.08K | +41.9% | $9.90M | 0.0% | ▲ Add | 3 | SEC ↗ ×5 |
| 13 | Morgan Stanley ✦ | 300.32K | +149.3% | $9.59M | 0.0% | ▲ Add | 4 | SEC ↗ ×6 |
| 14 | Citadel Advisors ✦ | 278.31K | +1707.7% | $8.89M | 0.0% | ▲ Add | 2 | SEC ↗ ×2 |
| 15 | Charles Schwab Investment… | 267.70K | +34.5% | $8.55M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 16 | Qube Research & Technologies Ltd | 266.93K | New | $8.53M | 0.0% | New | 1 | SEC ↗ |
| 17 | Bnp Paribas Financial Markets | 240.23K | +26.4% | $7.67M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 18 | Dimensional Fund Advisors Lp | 217.08K | +136.4% | $6.93M | 0.0% | ▲ Add | 3 | SEC ↗ ×3 |
| 19 | Franklin Resources Inc | 192.34K | +1383.0% | $6.14M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 20 | Raymond James Financial Inc | 180.88K | -26.8% | $5.78M | 0.0% | ▼ Trim | 3 | SEC ↗ ×2 |
| 21 | JPMorgan Chase ✦ | 178.26K | +166.9% | $5.74M | 0.0% | ▲ Add | 4 | SEC ↗ ×3 |
| 22 | Millennium Management ✦ | 177.67K | -19.8% | $5.67M | 0.0% | ▼ Trim | 8 | SEC ↗ |
| 23 | Adage Capital Partners ✦ | 162.00K | New | $5.17M | 0.0% | New | 1 | SEC ↗ |
| 24 | Victory Capital Management Inc | 152.59K | +901.9% | $4.87M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 25 | Ensign Peak Advisors, Inc | 146.54K | +97.8% | $4.68M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 26 | UBS Group AG | 129.94K | +111.1% | $4.15M | 0.0% | ▲ Add | 3 | SEC ↗ ×3 |
| 27 | BNP Paribas Asset Management… | 123.42K | -4.2% | $3.94M | 0.0% | ▼ Trim | 3 | SEC ↗ ×2 |
| 28 | Bank of New York Mellon Corp | 103.72K | +43.6% | $3.31M | 0.0% | ▲ Add | 3 | SEC ↗ ×3 |
| 29 | Russell Investments Group, Ltd. | 102.70K | +45.8% | $3.28M | 0.0% | ▲ Add | 3 | SEC ↗ ×8 |
| 30 | Nuveen, LLC | 78.83K | +55.0% | $2.52M | 0.0% | ▲ Add | 3 | SEC ↗ ×2 |
| 31 | Sei Investments Co | 66.61K | New | $2.13M | 0.0% | New | 1 | SEC ↗ |
| 32 | Squarepoint Ops LLC | 63.80K | +211.3% | $2.04M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 33 | Citigroup Inc | 62.28K | +939.5% | $1.99M | 0.0% | ▲ Add | 3 | SEC ↗ ×2 |
| 34 | Fisher Asset Management ✦ | 60.23K | +109.1% | $1.92M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 35 | Wellington Management ✦ | 59.60K | -22.8% | $1.90M | 0.0% | ▼ Trim | 9 | SEC ↗ ×3 |
| 36 | Alliancebernstein L.P. | 48.42K | +51.4% | $1.85M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 37 | Rhumbline Advisers | 52.04K | +31.2% | $1.66M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 38 | Td Asset Management Inc | 50.00K | 0.0% | $1.60M | 0.0% | Held | 2 | SEC ↗ |
| 39 | State Of Wisconsin Investment Board | 46.70K | +40.4% | $1.49M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 40 | Swiss National Bank | 44.70K | +69.3% | $1.43M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 41 | Manufacturers Life Insurance… | 44.33K | +10.2% | $1.42M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 42 | Deutsche Bank Ag\ | 36.94K | +80.2% | $1.18M | 0.0% | ▲ Add | 3 | SEC ↗ ×2 |
| 43 | Wells Fargo & Company/Mn | 33.56K | +187.5% | $1.07M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 44 | AQR Capital Management ✦ | 29.85K | +1.5% | $953,505 | 0.0% | ▲ Add | 5 | SEC ↗ ×6 |
| 45 | Tidal Investments LLC | 29.52K | New | $942,837 | 0.0% | New | 1 | SEC ↗ |
| 46 | Invesco Ltd. | 24.89K | -77.2% | $795,083 | 0.0% | ▼ Trim | 3 | SEC ↗ ×4 |
| 47 | Creative Planning | 21.80K | -9.0% | $696,387 | 0.0% | ▼ Trim | 3 | SEC ↗ ×2 |
| 48 | MIRAE ASSET GLOBAL ETFS HOLDINGS… | 21.36K | +46.1% | $683,131 | 0.0% | ▲ Add | 3 | SEC ↗ ×2 |
| 49 | LMR Partners LLP | 21.15K | New | $675,563 | 0.0% | New | 1 | SEC ↗ |
| 50 | Voya Investment Management Llc | 20.28K | -47.1% | $647,807 | 0.0% | ▼ Trim | 3 | SEC ↗ ×2 |
| 51 | Barclays Plc | 20.27K | -97.6% | $647,585 | 0.0% | ▼ Trim | 3 | SEC ↗ ×3 |
| 52 | D. E. Shaw & Co. ✦ | 20.19K | New | $644,837 | 0.0% | New | 1 | SEC ↗ ×2 |
| 53 | Legal & General Group Plc | 18.02K | +88.9% | $575,463 | 0.0% | ▲ Add | 3 | SEC ↗ ×3 |
| 54 | UBS AM, a distinct business unit of… | 17.69K | +125.8% | $564,955 | 0.0% | ▲ Add | 2 | SEC ↗ ×2 |
| 55 | Ameriprise Financial Inc | 16.92K | -88.3% | $540,425 | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 56 | New York State Common Retirement… | 12.92K | +74.1% | $412,761 | 0.0% | ▲ Add | 3 | SEC ↗ |
| 57 | Capstone Investment Advisors, Llc | 10.05K | New | $321,029 | 0.0% | New | 1 | SEC ↗ |
| 58 | Zurcher Kantonalbank (Zurich… | 8.52K | +6.0% | $272,225 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 59 | Canada Pension Plan Investment Board | 7.20K | -49.6% | $229,968 | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 60 | ProShare Advisors LLC | 6.76K | +10.1% | $216,074 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 61 | Mirae Asset Global Investments Co.… | 2.66K | -4.5% | $84,960 | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 62 | Osaic Holdings, Inc. | 1.19K | +116.0% | $38,007 | 0.0% | ▲ Add | 3 | SEC ↗ |
| 63 | Royal Bank Of Canada | 1.13K | +1179.5% | $36,000 | 0.0% | ▲ Add | 3 | SEC ↗ ×2 |
| 64 | Pacer Advisors, Inc. | 646 | New | $21,000 | 0.0% | New | 1 | SEC ↗ |
| 65 | Rockefeller Capital Management L.P. | 421 | 0.0% | $13,447 | 0.0% | Held | 3 | SEC ↗ ×2 |
| 66 | Federated Hermes, Inc. | 369 | -48.3% | $11,786 | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 67 | Pnc Financial Services Group, Inc. | 208 | -6.7% | $6,645 | 0.0% | ▼ Trim | 3 | SEC ↗ ×3 |
| 68 | Optiver Holding B.V. | 98 | -7.5% | $3,130 | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 69 | National Bank Of Canada /Fi/ | 15 | New | $480 | 0.0% | New | 1 | SEC ↗ |
“Their weight” = the position's share of that manager's reported 13F equity value — the conviction measure. ✦ = curated manager.
New buyers
| Qube Research & Technologies… | $8.53M | 0.0% |
| Adage Capital Partners | $5.17M | 0.0% |
| Sei Investments Co | $2.13M | 0.0% |
| Tidal Investments LLC | $942,837 | 0.0% |
| LMR Partners LLP | $675,563 | 0.0% |
| D. E. Shaw & Co. | $644,837 | 0.0% |
| Capstone Investment Advisors… | $321,029 | 0.0% |
| Pacer Advisors, Inc. | $21,000 | 0.0% |
| National Bank Of Canada /Fi/ | $480 | 0.0% |
Exited
| Balyasny Asset Management L.P. | $13.46M | was 0.0% |
| American Century Companies Inc | $1.84M | was 0.0% |
| Point72 Asset Management | $1.49M | was 0.0% |
| Tudor Investment Corp Et Al | $623,677 | was 0.0% |
| Susquehanna International… | $595,297 | was 0.0% |
| Jane Street Group, Llc | $389,473 | was 0.0% |
| Allianz Asset Management GmbH | $268,100 | was 0.0% |
| Us Bancorp \De\ | $421 | was 0.0% |
Full-market context: across ALL 13F filers (SEC structured data, Q1 2026): 163 holders, 65.87M shares, $2.48B reported. This is a different, older period than the tracked-universe figures above and the two are never mixed.
What else this security's tracked holders most often hold — shared-ownership counts, not fundamental relationships.
Open-market purchases (P)
Director · 972 sh @ 20.58 · $20,000
Open-market sales (S)
No open-market insider sales in our coverage window.
Awards, exercises and tax withholding are never counted as buys or sales here. Methodology
19.9% of class · View original SEC filing ↗