TYRA
Tyra Biosciences, Inc. · Healthcare · Biotechnology
Momentum inputs (comparable managers):
holder breadth +11.1% ·
share flow +28.7% ·
net new positions +10.0%
— formula
Broad accumulation — rising shares across more holders
All ownership figures: tracked 13F managers only, common-stock positions, reporting period Q4 2024
| Quarter | Holders | Δ | Shares | Reported value | New | Exits |
|---|---|---|---|---|---|---|
| Q2 2026 | 70 | +2 | 26.25M | $838.89M | +9 | −7 |
| Q1 2026 | 71 | +10 | 23.52M | $900.04M | +12 | −2 |
| Q4 2025 | 61 | -1 | 13.06M | $343.28M | +1 | −2 |
| Q3 2025 | 17 | 0 | 6.63M | $92.78M | — | — |
| Q2 2025 | 14 | +2 | 5.95M | $56.99M | +2 | — |
| Q1 2025 | 9 | -1 | 2.08M | $19.36M | — | −1 |
| Q4 2024 | 10 | +1 | 1.73M | $24.09M | +2 | −1 |
| Q3 2024 | 8 | +5 | 939.26K | $22.08M | +5 | — |
| Q2 2024 | 3 | — | 674.98K | $10.79M | — | — |
| # | Manager | Shares | Δ shares | Value | Their weight | Held | ||
|---|---|---|---|---|---|---|---|---|
| 1 | Geode Capital Management ✦ (passive) | 517.58K | -1.1% | $7.20M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 2 | Geode Capital Management ✦ (passive) | 517.58K | -1.1% | $7.20M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 3 | State Street Global Advisors ✦ (passive) | 407.57K | — | $5.67M | 0.0% | n/c | 1 | SEC ↗ |
| 4 | Millennium Management ✦ | 315.14K | +2900.2% | $4.38M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 5 | Adage Capital Partners ✦ | 200.00K | 0.0% | $2.78M | 0.0% | Held | 2 | SEC ↗ |
| 6 | Wellington Management ✦ | 94.86K | +4.4% | $1.32M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 7 | Wellington Management ✦ | 94.86K | +4.4% | $1.32M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 8 | Citadel Advisors ✦ | 55.59K | +132.1% | $772,659 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 9 | Marshall Wace ✦ | 54.08K | +175.7% | $751,671 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 10 | Marshall Wace ✦ | 54.08K | +175.7% | $751,671 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 11 | Two Sigma Investments ✦ | 46.27K | +18.1% | $643,139 | 0.0% | ▲ Add | 3 | SEC ↗ |
| 12 | Renaissance Technologies ✦ | 29.10K | New | $404,490 | 0.0% | New | 1 | SEC ↗ |
| 13 | Point72 Asset Management ✦ | 12.78K | New | $177,684 | 0.0% | New | 1 | SEC ↗ |
“Their weight” = the position's share of that manager's reported 13F equity value — the conviction measure. ✦ = curated manager.
New buyers
| Renaissance Technologies | $404,490 | 0.0% |
| Point72 Asset Management | $177,684 | 0.0% |
Exited
| D. E. Shaw & Co. | $752,391 | was 0.0% |
Full-market context: across ALL 13F filers (SEC structured data, Q1 2026): 163 holders, 65.87M shares, $2.48B reported. This is a different, older period than the tracked-universe figures above and the two are never mixed.
What else this security's tracked holders most often hold — shared-ownership counts, not fundamental relationships.