Security record
IONS
Ionis Pharmaceuticals, Inc. · Healthcare · Biotechnology
139Tracked holders
+2Δ holders
148.59MShares held
$11.08BReported value
+6New positions
−3Exits
Momentum inputs (comparable managers):
holder breadth +1.5% ·
share flow +4.3% ·
net new positions +2.2%
— formula
Broad accumulation — rising shares across more holders
All ownership figures: tracked 13F managers only, common-stock positions, reporting period Q2 2026
Ownership over time
| Quarter | Holders | Δ | Shares | Reported value | New | Exits |
|---|---|---|---|---|---|---|
| Q2 2026 | 139 | +2 | 148.59M | $11.08B | +6 | −3 |
| Q1 2026 | 139 | -2 | 142.62M | $9.86B | +6 | −9 |
| Q4 2025 | 142 | 0 | 143.10M | $10.36B | +1 | — |
| Q3 2025 | 25 | +4 | 95.56M | $6.25B | +5 | −2 |
| Q2 2025 | 19 | +1 | 95.25M | $3.76B | +1 | — |
| Q1 2025 | 15 | -1 | 43.90M | $1.32B | +1 | −2 |
| Q4 2024 | 16 | -1 | 43.25M | $1.51B | — | −1 |
| Q3 2024 | 16 | -1 | 34.86M | $1.40B | — | −1 |
| Q2 2024 | 17 | — | 24.68M | $1.18B | — | — |
Who holds it · Q2 2026
| # | Manager | Shares | Δ shares | Value | Their weight | Held | ||
|---|---|---|---|---|---|---|---|---|
| 1 | Fidelity (FMR) ✦ | 24.63M | +0.3% | $1.95B | 0.1% | ▲ Add | 5 | SEC ↗ |
| 2 | Fidelity (FMR) ✦ | 24.63M | +0.3% | $1.95B | 0.1% | ▲ Add | 5 | SEC ↗ |
| 3 | Fidelity (FMR) ✦ | 24.63M | +0.3% | $1.95B | 0.1% | ▲ Add | 5 | SEC ↗ |
| 4 | Fidelity (FMR) ✦ | 24.63M | +0.3% | $1.95B | 0.1% | ▲ Add | 5 | SEC ↗ |
| 5 | Fidelity (FMR) ✦ | 24.63M | +0.3% | $1.95B | 0.1% | ▲ Add | 5 | SEC ↗ |
| 6 | Fidelity (FMR) ✦ | 24.63M | +0.3% | $1.95B | 0.1% | ▲ Add | 5 | SEC ↗ |
| 7 | Capital World Investors ✦ | 21.67M | +2.3% | $1.72B | 0.2% | ▲ Add | 9 | SEC ↗ |
| 8 | BlackRock ✦ (passive) | 10.70M | +2.5% | $848.77M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 9 | BlackRock ✦ (passive) | 10.70M | +2.5% | $848.77M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 10 | BlackRock ✦ (passive) | 10.70M | +2.5% | $848.77M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 11 | BlackRock ✦ (passive) | 10.70M | +2.5% | $848.77M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 12 | BlackRock ✦ (passive) | 10.70M | +2.5% | $848.77M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 13 | BlackRock ✦ (passive) | 10.70M | +2.5% | $848.77M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 14 | BlackRock ✦ (passive) | 10.70M | +2.5% | $848.77M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 15 | BlackRock ✦ (passive) | 10.70M | +2.5% | $848.77M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 16 | BlackRock ✦ (passive) | 10.70M | +2.5% | $848.77M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 17 | BlackRock ✦ (passive) | 10.70M | +2.5% | $848.77M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 18 | BlackRock ✦ (passive) | 10.70M | +2.5% | $848.77M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 19 | BlackRock ✦ (passive) | 10.70M | +2.5% | $848.77M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 20 | BlackRock ✦ (passive) | 10.70M | +2.5% | $848.77M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 21 | BlackRock ✦ (passive) | 10.70M | +2.5% | $848.77M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 22 | BlackRock ✦ (passive) | 10.70M | +2.5% | $848.77M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 23 | BlackRock ✦ (passive) | 10.70M | +2.5% | $848.77M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 24 | BlackRock ✦ (passive) | 10.70M | +2.5% | $848.77M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 25 | BlackRock ✦ (passive) | 10.70M | +2.5% | $848.77M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 26 | BlackRock ✦ (passive) | 10.70M | +2.5% | $848.77M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 27 | BlackRock ✦ (passive) | 10.70M | +2.5% | $848.77M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 28 | Wellington Management ✦ | 7.65M | +19.7% | $606.68M | 0.1% | ▲ Add | 9 | SEC ↗ |
| 29 | Wellington Management ✦ | 7.65M | +19.7% | $606.68M | 0.1% | ▲ Add | 9 | SEC ↗ |
| 30 | Wellington Management ✦ | 7.65M | +19.7% | $606.68M | 0.1% | ▲ Add | 9 | SEC ↗ |
| 31 | Wellington Management ✦ | 7.65M | +19.7% | $606.68M | 0.1% | ▲ Add | 9 | SEC ↗ |
| 32 | Wellington Management ✦ | 7.65M | +19.7% | $606.68M | 0.1% | ▲ Add | 9 | SEC ↗ |
| 33 | Wellington Management ✦ | 7.65M | +19.7% | $606.68M | 0.1% | ▲ Add | 9 | SEC ↗ |
| 34 | Wellington Management ✦ | 7.65M | +19.7% | $606.68M | 0.1% | ▲ Add | 9 | SEC ↗ |
| 35 | Wellington Management ✦ | 7.65M | +19.7% | $606.68M | 0.1% | ▲ Add | 9 | SEC ↗ |
| 36 | Wellington Management ✦ | 7.65M | +19.7% | $606.68M | 0.1% | ▲ Add | 9 | SEC ↗ |
| 37 | Wellington Management ✦ | 7.65M | +19.7% | $606.68M | 0.1% | ▲ Add | 9 | SEC ↗ |
| 38 | Wellington Management ✦ | 7.65M | +19.7% | $606.68M | 0.1% | ▲ Add | 9 | SEC ↗ |
| 39 | Wellington Management ✦ | 7.65M | +19.7% | $606.68M | 0.1% | ▲ Add | 9 | SEC ↗ |
| 40 | Vanguard Capital Management Llc | 7.21M | +1.3% | $571.80M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 41 | Two Sigma Investments ✦ | 6.25M | +6.7% | $495.75M | 0.4% | ▲ Add | 9 | SEC ↗ |
| 42 | Royal Bank Of Canada | 6.18M | +62.6% | $490.21M | 0.1% | ▲ Add | 3 | SEC ↗ |
| 43 | Royal Bank Of Canada | 6.18M | +62.6% | $490.21M | 0.1% | ▲ Add | 3 | SEC ↗ |
| 44 | Royal Bank Of Canada | 6.18M | +62.6% | $490.21M | 0.1% | ▲ Add | 3 | SEC ↗ |
| 45 | Royal Bank Of Canada | 6.18M | +62.6% | $490.21M | 0.1% | ▲ Add | 3 | SEC ↗ |
| 46 | Royal Bank Of Canada | 6.18M | +62.6% | $490.21M | 0.1% | ▲ Add | 3 | SEC ↗ |
| 47 | Royal Bank Of Canada | 6.18M | +62.6% | $490.21M | 0.1% | ▲ Add | 3 | SEC ↗ |
| 48 | Royal Bank Of Canada | 6.18M | +62.6% | $490.21M | 0.1% | ▲ Add | 3 | SEC ↗ |
| 49 | Royal Bank Of Canada | 6.18M | +62.6% | $490.21M | 0.1% | ▲ Add | 3 | SEC ↗ |
| 50 | Royal Bank Of Canada | 6.18M | +62.6% | $490.21M | 0.1% | ▲ Add | 3 | SEC ↗ |
| 51 | Royal Bank Of Canada | 6.18M | +62.6% | $490.21M | 0.1% | ▲ Add | 3 | SEC ↗ |
| 52 | Royal Bank Of Canada | 6.18M | +62.6% | $490.21M | 0.1% | ▲ Add | 3 | SEC ↗ |
| 53 | Royal Bank Of Canada | 6.18M | +62.6% | $490.21M | 0.1% | ▲ Add | 3 | SEC ↗ |
| 54 | Royal Bank Of Canada | 6.18M | +62.6% | $490.21M | 0.1% | ▲ Add | 3 | SEC ↗ |
| 55 | Royal Bank Of Canada | 6.18M | +62.6% | $490.21M | 0.1% | ▲ Add | 3 | SEC ↗ |
| 56 | State Street Global Advisors ✦ (passive) | 4.33M | +8.5% | $343.71M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 57 | State Street Global Advisors ✦ (passive) | 4.33M | +8.5% | $343.71M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 58 | Geode Capital Management ✦ (passive) | 3.58M | -10.1% | $294.75M | 0.0% | ▼ Trim | 9 | SEC ↗ |
| 59 | Geode Capital Management ✦ (passive) | 3.58M | -10.1% | $294.75M | 0.0% | ▼ Trim | 9 | SEC ↗ |
| 60 | T. Rowe Price ✦ | 3.18M | +5.3% | $252.50M | 0.0% | ▲ Add | 9 | SEC ↗ |
| 61 | T. Rowe Price ✦ | 3.18M | +5.3% | $252.50M | 0.0% | ▲ Add | 9 | SEC ↗ |
| 62 | JPMorgan Chase ✦ | 2.67M | +13.0% | $216.20M | 0.0% | ▲ Add | 4 | SEC ↗ |
| 63 | JPMorgan Chase ✦ | 2.67M | +13.0% | $216.20M | 0.0% | ▲ Add | 4 | SEC ↗ |
| 64 | JPMorgan Chase ✦ | 2.67M | +13.0% | $216.20M | 0.0% | ▲ Add | 4 | SEC ↗ |
| 65 | JPMorgan Chase ✦ | 2.67M | +13.0% | $216.20M | 0.0% | ▲ Add | 4 | SEC ↗ |
| 66 | JPMorgan Chase ✦ | 2.67M | +13.0% | $216.20M | 0.0% | ▲ Add | 4 | SEC ↗ |
| 67 | JPMorgan Chase ✦ | 2.67M | +13.0% | $216.20M | 0.0% | ▲ Add | 4 | SEC ↗ |
| 68 | JPMorgan Chase ✦ | 2.67M | +13.0% | $216.20M | 0.0% | ▲ Add | 4 | SEC ↗ |
| 69 | JPMorgan Chase ✦ | 2.67M | +13.0% | $216.20M | 0.0% | ▲ Add | 4 | SEC ↗ |
| 70 | JPMorgan Chase ✦ | 2.67M | +13.0% | $216.20M | 0.0% | ▲ Add | 4 | SEC ↗ |
| 71 | JPMorgan Chase ✦ | 2.67M | +13.0% | $216.20M | 0.0% | ▲ Add | 4 | SEC ↗ |
| 72 | JPMorgan Chase ✦ | 2.67M | +13.0% | $216.20M | 0.0% | ▲ Add | 4 | SEC ↗ |
| 73 | Artisan Partners Limited Partnership | 2.64M | +28.3% | $209.33M | 0.3% | ▲ Add | 3 | SEC ↗ |
| 74 | Tweedy, Browne ✦ | 2.28M | +0.2% | $180.81M | 13.7% | ▲ Add | 9 | SEC ↗ |
| 75 | Goldman Sachs Group ✦ | 2.11M | +24.1% | $167.30M | 0.0% | ▲ Add | 4 | SEC ↗ |
| 76 | Goldman Sachs Group ✦ | 2.11M | +24.1% | $167.30M | 0.0% | ▲ Add | 4 | SEC ↗ |
| 77 | Goldman Sachs Group ✦ | 2.11M | +24.1% | $167.30M | 0.0% | ▲ Add | 4 | SEC ↗ |
| 78 | Goldman Sachs Group ✦ | 2.11M | +24.1% | $167.30M | 0.0% | ▲ Add | 4 | SEC ↗ |
| 79 | Goldman Sachs Group ✦ | 2.11M | +24.1% | $167.30M | 0.0% | ▲ Add | 4 | SEC ↗ |
| 80 | American Century Companies Inc | 1.95M | +17.0% | $154.38M | 0.1% | ▲ Add | 3 | SEC ↗ |
| 81 | Franklin Resources Inc | 1.62M | +3.1% | $128.72M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 82 | Franklin Resources Inc | 1.62M | +3.1% | $128.72M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 83 | Franklin Resources Inc | 1.62M | +3.1% | $128.72M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 84 | Franklin Resources Inc | 1.62M | +3.1% | $128.72M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 85 | Charles Schwab Investment… | 1.61M | +1.4% | $127.26M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 86 | Charles Schwab Investment… | 1.61M | +1.4% | $127.26M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 87 | Barclays Plc | 1.60M | +453.1% | $127.11M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 88 | Barclays Plc | 1.60M | +453.1% | $127.11M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 89 | Barclays Plc | 1.60M | +453.1% | $127.11M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 90 | Barclays Plc | 1.60M | +453.1% | $127.11M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 91 | Pictet Asset Management Holding SA | 1.60M | +11.3% | $126.98M | 0.1% | ▲ Add | 3 | SEC ↗ |
| 92 | UBS AM, a distinct business unit of… | 1.45M | -1.4% | $115.34M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 93 | UBS AM, a distinct business unit of… | 1.45M | -1.4% | $115.34M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 94 | UBS AM, a distinct business unit of… | 1.45M | -1.4% | $115.34M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 95 | UBS AM, a distinct business unit of… | 1.45M | -1.4% | $115.34M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 96 | UBS AM, a distinct business unit of… | 1.45M | -1.4% | $115.34M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 97 | UBS AM, a distinct business unit of… | 1.45M | -1.4% | $115.34M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 98 | UBS AM, a distinct business unit of… | 1.45M | -1.4% | $115.34M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 99 | UBS AM, a distinct business unit of… | 1.45M | -1.4% | $115.34M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 100 | UBS AM, a distinct business unit of… | 1.45M | -1.4% | $115.34M | 0.0% | ▼ Trim | 3 | SEC ↗ |
“Their weight” = the position's share of that manager's reported 13F equity value — the conviction measure. ✦ = curated manager.
New buyers
| No new tracked buyers this quarter. |
Exited
| Tudor Investment Corp Et Al | $3.62M | was 0.0% |
| Loomis Sayles & Co L P | $2.15M | was 0.0% |
| Principal Financial Group Inc | $527,056 | was 0.0% |
Full-market context: across ALL 13F filers (SEC structured data, Q1 2026): 490 holders, 170.17M shares, $11.94B reported. This is a different, older period than the tracked-universe figures above and the two are never mixed.
Frequently co-owned
What else this security's tracked holders most often hold — shared-ownership counts, not fundamental relationships.
Provenance: Ownership from parsed 13F common-stock positions (tracked universe, comparable sets for changes); insider rows from Forms 3/4/5; stakes from Schedules 13D/13G; every filing links to its original on SEC EDGAR.
Reporting period: Q2 2026 ·
Methodology ·
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