Security record
IONS
Ionis Pharmaceuticals, Inc. · Healthcare · Biotechnology
139Tracked holders
+2Δ holders
148.59MShares held
$11.08BReported value
+6New positions
−3Exits
Momentum inputs (comparable managers):
holder breadth +1.5% ·
share flow +4.3% ·
net new positions +2.2%
— formula
Broad accumulation — rising shares across more holders
All ownership figures: tracked 13F managers only, common-stock positions, reporting period Q2 2026
Ownership over time
| Quarter | Holders | Δ | Shares | Reported value | New | Exits |
|---|---|---|---|---|---|---|
| Q2 2026 | 139 | +2 | 148.59M | $11.08B | +6 | −3 |
| Q1 2026 | 139 | -2 | 142.62M | $9.86B | +6 | −9 |
| Q4 2025 | 142 | 0 | 143.10M | $10.36B | +1 | — |
| Q3 2025 | 25 | +4 | 95.56M | $6.25B | +5 | −2 |
| Q2 2025 | 19 | +1 | 95.25M | $3.76B | +1 | — |
| Q1 2025 | 15 | -1 | 43.90M | $1.32B | +1 | −2 |
| Q4 2024 | 16 | -1 | 43.25M | $1.51B | — | −1 |
| Q3 2024 | 16 | -1 | 34.86M | $1.40B | — | −1 |
| Q2 2024 | 17 | — | 24.68M | $1.18B | — | — |
Who holds it · Q2 2026
| # | Manager | Shares | Δ shares | Value | Their weight | Held | ||
|---|---|---|---|---|---|---|---|---|
| 1 | Fidelity (FMR) ✦ | 24.63M | +0.3% | $1.95B | 0.1% | ▲ Add | 5 | SEC ↗ ×6 |
| 2 | Capital World Investors ✦ | 21.67M | +2.3% | $1.72B | 0.2% | ▲ Add | 9 | SEC ↗ |
| 3 | BlackRock ✦ (passive) | 10.70M | +2.5% | $848.77M | 0.0% | ▲ Add | 5 | SEC ↗ ×20 |
| 4 | Wellington Management ✦ | 7.65M | +19.7% | $606.68M | 0.1% | ▲ Add | 9 | SEC ↗ ×12 |
| 5 | Vanguard Capital Management Llc | 7.21M | +1.3% | $571.80M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 6 | Two Sigma Investments ✦ | 6.25M | +6.7% | $495.75M | 0.4% | ▲ Add | 9 | SEC ↗ |
| 7 | Royal Bank Of Canada | 6.18M | +62.6% | $490.21M | 0.1% | ▲ Add | 3 | SEC ↗ ×14 |
| 8 | State Street Global Advisors ✦ (passive) | 4.33M | +8.5% | $343.71M | 0.0% | ▲ Add | 7 | SEC ↗ ×2 |
| 9 | Geode Capital Management ✦ (passive) | 3.58M | -10.1% | $294.75M | 0.0% | ▼ Trim | 9 | SEC ↗ ×2 |
| 10 | T. Rowe Price ✦ | 3.18M | +5.3% | $252.50M | 0.0% | ▲ Add | 9 | SEC ↗ ×2 |
| 11 | JPMorgan Chase ✦ | 2.67M | +13.0% | $216.20M | 0.0% | ▲ Add | 4 | SEC ↗ ×11 |
| 12 | Artisan Partners Limited Partnership | 2.64M | +28.3% | $209.33M | 0.3% | ▲ Add | 3 | SEC ↗ |
| 13 | Tweedy, Browne ✦ | 2.28M | +0.2% | $180.81M | 13.7% | ▲ Add | 9 | SEC ↗ |
| 14 | Goldman Sachs Group ✦ | 2.11M | +24.1% | $167.30M | 0.0% | ▲ Add | 4 | SEC ↗ ×5 |
| 15 | American Century Companies Inc | 1.95M | +17.0% | $154.38M | 0.1% | ▲ Add | 3 | SEC ↗ |
| 16 | Franklin Resources Inc | 1.62M | +3.1% | $128.72M | 0.0% | ▲ Add | 3 | SEC ↗ ×4 |
| 17 | Charles Schwab Investment… | 1.61M | +1.4% | $127.26M | 0.0% | ▲ Add | 3 | SEC ↗ ×2 |
| 18 | Barclays Plc | 1.60M | +453.1% | $127.11M | 0.0% | ▲ Add | 3 | SEC ↗ ×4 |
| 19 | Pictet Asset Management Holding SA | 1.60M | +11.3% | $126.98M | 0.1% | ▲ Add | 3 | SEC ↗ |
| 20 | UBS AM, a distinct business unit of… | 1.45M | -1.4% | $115.34M | 0.0% | ▼ Trim | 3 | SEC ↗ ×13 |
| 21 | Alyeska Investment Group, L.P. | 1.42M | +199.7% | $112.43M | 0.3% | ▲ Add | 3 | SEC ↗ |
| 22 | Nomura Asset Management… | 1.30M | +65.6% | $103.11M | 0.2% | ▲ Add | 3 | SEC ↗ |
| 23 | Morgan Stanley ✦ | 1.28M | +24.8% | $101.61M | 0.0% | ▲ Add | 4 | SEC ↗ ×11 |
| 24 | Invesco Ltd. | 1.12M | -12.3% | $88.86M | 0.0% | ▼ Trim | 3 | SEC ↗ ×6 |
| 25 | Northern Trust Corp | 913.61K | +5.2% | $72.44M | 0.0% | ▲ Add | 3 | SEC ↗ ×4 |
| 26 | Capital International Investors | 823.76K | New | $65.32M | 0.0% | New | 1 | SEC ↗ |
| 27 | Bank Of America Corp /De/ | 790.99K | -5.9% | $62.72M | 0.0% | ▼ Trim | 3 | SEC ↗ ×6 |
| 28 | BNP Paribas Asset Management… | 734.22K | -81.8% | $58.22M | 0.1% | ▼ Trim | 3 | SEC ↗ ×4 |
| 29 | Nuveen, LLC | 726.28K | +12.0% | $57.59M | 0.0% | ▲ Add | 3 | SEC ↗ ×3 |
| 30 | Connor, Clark & Lunn Investment… | 684.24K | -21.7% | $54.25M | 0.1% | ▼ Trim | 3 | SEC ↗ |
| 31 | Massachusetts Financial Services Co… | 651.82K | -2.1% | $51.68M | 0.0% | ▼ Trim | 3 | SEC ↗ ×2 |
| 32 | Neuberger Berman Group LLC | 633.53K | +42.9% | $50.23M | 0.0% | ▲ Add | 3 | SEC ↗ ×2 |
| 33 | Arrowstreet Capital ✦ | 632.03K | -14.3% | $50.11M | 0.0% | ▼ Trim | 4 | SEC ↗ |
| 34 | UBS Group AG | 624.87K | -22.7% | $49.55M | 0.0% | ▼ Trim | 3 | SEC ↗ ×6 |
| 35 | Renaissance Technologies ✦ | 559.41K | +83.1% | $44.36M | 0.1% | ▲ Add | 9 | SEC ↗ |
| 36 | Bank of New York Mellon Corp | 542.45K | +5.4% | $43.01M | 0.0% | ▲ Add | 3 | SEC ↗ ×11 |
| 37 | Jane Street Group, Llc | 503.65K | +162.6% | $39.93M | 0.0% | ▲ Add | 3 | SEC ↗ ×2 |
| 38 | New York State Common Retirement… | 500.05K | +42.7% | $39.65M | 0.1% | ▲ Add | 3 | SEC ↗ |
| 39 | Bnp Paribas Financial Markets | 454.65K | -5.2% | $36.05M | 0.0% | ▼ Trim | 3 | SEC ↗ ×2 |
| 40 | Nomura Holdings Inc | 438.17K | +120.0% | $34.74M | 0.1% | ▲ Add | 3 | SEC ↗ ×2 |
| 41 | First Trust Advisors Lp | 427.20K | -8.8% | $33.87M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 42 | Td Asset Management Inc | 340.55K | -35.7% | $27.00M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 43 | Qube Research & Technologies Ltd | 333.95K | +679.2% | $26.48M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 44 | Capital Research Global Investors | 331.94K | +2.8% | $26.32M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 45 | Alliancebernstein L.P. | 340.45K | -15.0% | $25.56M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 46 | Swiss National Bank | 315.00K | +3.5% | $24.98M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 47 | ARK Investment Management ✦ | 300.77K | +4.2% | $23.85M | 0.2% | ▲ Add | 9 | SEC ↗ |
| 48 | Legal & General Group Plc | 299.18K | +1.5% | $23.72M | 0.0% | ▲ Add | 3 | SEC ↗ ×3 |
| 49 | D. E. Shaw & Co. ✦ | 297.04K | -30.9% | $23.55M | 0.0% | ▼ Trim | 4 | SEC ↗ ×2 |
| 50 | Millennium Management ✦ | 288.87K | -72.5% | $22.90M | 0.0% | ▼ Trim | 9 | SEC ↗ |
| 51 | Aberdeen Group plc | 277.40K | +143.7% | $22.00M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 52 | California Public Employees… | 270.84K | +6.0% | $21.48M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 53 | Focus Partners Wealth | 5.32M | -2.2% | $19.79M | 0.0% | ▼ Trim | 3 | SEC ↗ ×2 |
| 54 | Raymond James Financial Inc | 237.35K | +0.9% | $18.82M | 0.0% | ▲ Add | 3 | SEC ↗ ×4 |
| 55 | Citadel Advisors ✦ | 236.28K | -74.9% | $18.73M | 0.0% | ▼ Trim | 9 | SEC ↗ ×3 |
| 56 | Universal- Beteiligungs- und… | 233.50K | +6.3% | $18.51M | 0.0% | ▲ Add | 3 | SEC ↗ ×2 |
| 57 | Wells Fargo & Company/Mn | 226.21K | +19.1% | $17.94M | 0.0% | ▲ Add | 3 | SEC ↗ ×8 |
| 58 | Stifel Financial Corp | 202.98K | +3.2% | $16.09M | 0.0% | ▲ Add | 3 | SEC ↗ ×4 |
| 59 | Corient Private Wealth LP | 196.79K | +0.1% | $15.60M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 60 | Hsbc Holdings Plc | 188.40K | +1.3% | $15.05M | 0.0% | ▲ Add | 3 | SEC ↗ ×5 |
| 61 | Hrt Financial Lp | 186.80K | -25.9% | $14.81M | 0.0% | ▼ Trim | 3 | SEC ↗ ×2 |
| 62 | State Of Wisconsin Investment Board | 4.09M | +32.2% | $13.71M | 0.0% | ▲ Add | 3 | SEC ↗ ×2 |
| 63 | Deutsche Bank Ag\ | 169.61K | +6.1% | $13.45M | 0.0% | ▲ Add | 3 | SEC ↗ ×5 |
| 64 | Rhumbline Advisers | 164.91K | -4.9% | $13.08M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 65 | DZ BANK AG Deutsche Zentral… | 151.30K | -9.8% | $12.00M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 66 | Adage Capital Partners ✦ | 150.00K | +200.0% | $11.89M | 0.0% | ▲ Add | 9 | SEC ↗ |
| 67 | Fisher Asset Management ✦ | 137.18K | -3.1% | $10.88M | 0.0% | ▼ Trim | 4 | SEC ↗ |
| 68 | Lazard Asset Management Llc | 132.48K | +421.4% | $10.50M | 0.0% | ▲ Add | 3 | SEC ↗ ×2 |
| 69 | State Board Of Administration Of… | 131.82K | -3.0% | $10.45M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 70 | Sei Investments Co | 127.87K | -51.2% | $10.14M | 0.0% | ▼ Trim | 3 | SEC ↗ ×3 |
| 71 | Gotham Asset Management ✦ | 121.25K | +22.5% | $9.61M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 72 | Manufacturers Life Insurance… | 120.68K | -19.3% | $9.57M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 73 | Norges Bank ✦ (passive) | 114.36K | New | $9.07M | 0.0% | New | 1 | SEC ↗ |
| 74 | Squarepoint Ops LLC | 109.38K | -84.3% | $8.67M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 75 | Envestnet Asset Management Inc | 98.12K | +5.1% | $7.78M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 76 | Swedbank AB | 95.67K | +196.6% | $7.59M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 77 | Citigroup Inc | 86.75K | -40.8% | $6.88M | 0.0% | ▼ Trim | 3 | SEC ↗ ×4 |
| 78 | Dimensional Fund Advisors Lp | 84.75K | -68.3% | $6.72M | 0.0% | ▼ Trim | 3 | SEC ↗ ×2 |
| 79 | Assenagon Asset Management S.A. | 81.85K | +143.1% | $6.49M | 0.0% | ▲ Add | 3 | SEC ↗ ×2 |
| 80 | Russell Investments Group, Ltd. | 81.32K | +29.2% | $6.45M | 0.0% | ▲ Add | 3 | SEC ↗ ×6 |
| 81 | Bank Of Nova Scotia | 68.55K | New | $5.44M | 0.0% | New | 1 | SEC ↗ |
| 82 | Ameriprise Financial Inc | 67.70K | -89.7% | $5.37M | 0.0% | ▼ Trim | 3 | SEC ↗ ×3 |
| 83 | Voya Investment Management Llc | 66.30K | -4.1% | $5.26M | 0.0% | ▼ Trim | 3 | SEC ↗ ×3 |
| 84 | Victory Capital Management Inc | 65.97K | -39.3% | $5.23M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 85 | Zurcher Kantonalbank (Zurich… | 65.08K | +8.0% | $5.16M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 86 | Quantinno Capital Management LP | 64.91K | +17.0% | $5.15M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 87 | Schroder Investment Management Group | 58.87K | New | $4.75M | 0.0% | New | 1 | SEC ↗ ×2 |
| 88 | Creative Planning | 50.55K | -3.2% | $4.01M | 0.0% | ▼ Trim | 3 | SEC ↗ ×2 |
| 89 | Tidal Investments LLC | 49.18K | +42.8% | $3.90M | 0.0% | ▲ Add | 3 | SEC ↗ ×2 |
| 90 | Jones Financial Companies Lllp | 47.44K | +77.5% | $3.85M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 91 | Sumitomo Mitsui Trust Group, Inc. | 47.84K | -41.6% | $3.79M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 92 | Prudential Financial Inc | 35.34K | +0.2% | $2.80M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 93 | Canada Pension Plan Investment Board | 33.30K | +136.2% | $2.64M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 94 | Blair William & Co/Il | 31.61K | -6.7% | $2.51M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 95 | LMR Partners LLP | 30.80K | +105.3% | $2.44M | 0.0% | ▲ Add | 3 | SEC ↗ ×2 |
| 96 | Peak6 Llc | 29.46K | -14.4% | $2.34M | 0.1% | ▼ Trim | 3 | SEC ↗ |
| 97 | LPL Financial LLC | 27.87K | -12.7% | $2.21M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 98 | Bank Of Montreal /Can/ | 25.78K | -3.0% | $2.04M | 0.0% | ▼ Trim | 3 | SEC ↗ ×5 |
| 99 | AQR Capital Management ✦ | 22.06K | -23.4% | $1.75M | 0.0% | ▼ Trim | 4 | SEC ↗ ×4 |
| 100 | Cetera Investment Advisers | 21.81K | +93.3% | $1.73M | 0.0% | ▲ Add | 3 | SEC ↗ |
“Their weight” = the position's share of that manager's reported 13F equity value — the conviction measure. ✦ = curated manager.
New buyers
| Capital International… | $65.32M | 0.0% |
| Norges Bank | $9.07M | 0.0% |
| Bank Of Nova Scotia | $5.44M | 0.0% |
| Schroder Investment… | $4.75M | 0.0% |
Exited
| Tudor Investment Corp Et Al | $3.62M | was 0.0% |
| Loomis Sayles & Co L P | $2.15M | was 0.0% |
| Principal Financial Group Inc | $527,056 | was 0.0% |
Full-market context: across ALL 13F filers (SEC structured data, Q1 2026): 490 holders, 170.17M shares, $11.94B reported. This is a different, older period than the tracked-universe figures above and the two are never mixed.
Frequently co-owned
What else this security's tracked holders most often hold — shared-ownership counts, not fundamental relationships.
Provenance: Ownership from parsed 13F common-stock positions (tracked universe, comparable sets for changes); insider rows from Forms 3/4/5; stakes from Schedules 13D/13G; every filing links to its original on SEC EDGAR.
Reporting period: Q2 2026 ·
Methodology ·
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