Security record · archived quarter
IONS
Ionis Pharmaceuticals, Inc. · Healthcare · Biotechnology
139Tracked holders
-2Δ holders
142.62MShares held
$9.86BReported value
+6New positions
−9Exits
Momentum inputs (comparable managers):
holder breadth -1.4% ·
share flow +6.9% ·
net new positions -2.2%
— formula
Concentrated accumulation — rising shares among fewer holders
All ownership figures: tracked 13F managers only, common-stock positions, reporting period Q1 2026
Ownership over time
| Quarter | Holders | Δ | Shares | Reported value | New | Exits |
|---|---|---|---|---|---|---|
| Q2 2026 | 139 | +2 | 148.59M | $11.08B | +6 | −3 |
| Q1 2026 | 139 | -2 | 142.62M | $9.86B | +6 | −9 |
| Q4 2025 | 142 | 0 | 143.10M | $10.36B | +1 | — |
| Q3 2025 | 25 | +4 | 95.56M | $6.25B | +5 | −2 |
| Q2 2025 | 19 | +1 | 95.25M | $3.76B | +1 | — |
| Q1 2025 | 15 | -1 | 43.90M | $1.32B | +1 | −2 |
| Q4 2024 | 16 | -1 | 43.25M | $1.51B | — | −1 |
| Q3 2024 | 16 | -1 | 34.86M | $1.40B | — | −1 |
| Q2 2024 | 17 | — | 24.68M | $1.18B | — | — |
Who holds it · Q1 2026
| # | Manager | Shares | Δ shares | Value | Their weight | Held | ||
|---|---|---|---|---|---|---|---|---|
| 1 | Fidelity (FMR) ✦ | 24.56M | +2.0% | $1.84B | 0.1% | ▲ Add | 4 | SEC ↗ |
| 2 | Fidelity (FMR) ✦ | 24.56M | +2.0% | $1.84B | 0.1% | ▲ Add | 4 | SEC ↗ |
| 3 | Fidelity (FMR) ✦ | 24.56M | +2.0% | $1.84B | 0.1% | ▲ Add | 4 | SEC ↗ |
| 4 | Fidelity (FMR) ✦ | 24.56M | +2.0% | $1.84B | 0.1% | ▲ Add | 4 | SEC ↗ |
| 5 | Fidelity (FMR) ✦ | 24.56M | +2.0% | $1.84B | 0.1% | ▲ Add | 4 | SEC ↗ |
| 6 | Fidelity (FMR) ✦ | 24.56M | +2.0% | $1.84B | 0.1% | ▲ Add | 4 | SEC ↗ |
| 7 | Capital World Investors ✦ | 21.19M | +18.0% | $1.59B | 0.2% | ▲ Add | 8 | SEC ↗ |
| 8 | BlackRock ✦ (passive) | 10.44M | -1.9% | $784.13M | 0.0% | ▼ Trim | 4 | SEC ↗ |
| 9 | BlackRock ✦ (passive) | 10.44M | -1.9% | $784.13M | 0.0% | ▼ Trim | 4 | SEC ↗ |
| 10 | BlackRock ✦ (passive) | 10.44M | -1.9% | $784.13M | 0.0% | ▼ Trim | 4 | SEC ↗ |
| 11 | BlackRock ✦ (passive) | 10.44M | -1.9% | $784.13M | 0.0% | ▼ Trim | 4 | SEC ↗ |
| 12 | BlackRock ✦ (passive) | 10.44M | -1.9% | $784.13M | 0.0% | ▼ Trim | 4 | SEC ↗ |
| 13 | BlackRock ✦ (passive) | 10.44M | -1.9% | $784.13M | 0.0% | ▼ Trim | 4 | SEC ↗ |
| 14 | BlackRock ✦ (passive) | 10.44M | -1.9% | $784.13M | 0.0% | ▼ Trim | 4 | SEC ↗ |
| 15 | BlackRock ✦ (passive) | 10.44M | -1.9% | $784.13M | 0.0% | ▼ Trim | 4 | SEC ↗ |
| 16 | BlackRock ✦ (passive) | 10.44M | -1.9% | $784.13M | 0.0% | ▼ Trim | 4 | SEC ↗ |
| 17 | BlackRock ✦ (passive) | 10.44M | -1.9% | $784.13M | 0.0% | ▼ Trim | 4 | SEC ↗ |
| 18 | BlackRock ✦ (passive) | 10.44M | -1.9% | $784.13M | 0.0% | ▼ Trim | 4 | SEC ↗ |
| 19 | BlackRock ✦ (passive) | 10.44M | -1.9% | $784.13M | 0.0% | ▼ Trim | 4 | SEC ↗ |
| 20 | BlackRock ✦ (passive) | 10.44M | -1.9% | $784.13M | 0.0% | ▼ Trim | 4 | SEC ↗ |
| 21 | BlackRock ✦ (passive) | 10.44M | -1.9% | $784.13M | 0.0% | ▼ Trim | 4 | SEC ↗ |
| 22 | BlackRock ✦ (passive) | 10.44M | -1.9% | $784.13M | 0.0% | ▼ Trim | 4 | SEC ↗ |
| 23 | BlackRock ✦ (passive) | 10.44M | -1.9% | $784.13M | 0.0% | ▼ Trim | 4 | SEC ↗ |
| 24 | BlackRock ✦ (passive) | 10.44M | -1.9% | $784.13M | 0.0% | ▼ Trim | 4 | SEC ↗ |
| 25 | BlackRock ✦ (passive) | 10.44M | -1.9% | $784.13M | 0.0% | ▼ Trim | 4 | SEC ↗ |
| 26 | BlackRock ✦ (passive) | 10.44M | -1.9% | $784.13M | 0.0% | ▼ Trim | 4 | SEC ↗ |
| 27 | BlackRock ✦ (passive) | 10.44M | -1.9% | $784.13M | 0.0% | ▼ Trim | 4 | SEC ↗ |
| 28 | BlackRock ✦ (passive) | 10.44M | -1.9% | $784.13M | 0.0% | ▼ Trim | 4 | SEC ↗ |
| 29 | BlackRock ✦ (passive) | 10.44M | -1.9% | $784.13M | 0.0% | ▼ Trim | 4 | SEC ↗ |
| 30 | BlackRock ✦ (passive) | 10.44M | -1.9% | $784.13M | 0.0% | ▼ Trim | 4 | SEC ↗ |
| 31 | Vanguard Capital Management Llc | 7.12M | — | $534.52M | 0.0% | n/c | 1 | SEC ↗ |
| 32 | Wellington Management ✦ | 6.39M | +2.1% | $479.96M | 0.1% | ▲ Add | 8 | SEC ↗ |
| 33 | Wellington Management ✦ | 6.39M | +2.1% | $479.96M | 0.1% | ▲ Add | 8 | SEC ↗ |
| 34 | Wellington Management ✦ | 6.39M | +2.1% | $479.96M | 0.1% | ▲ Add | 8 | SEC ↗ |
| 35 | Wellington Management ✦ | 6.39M | +2.1% | $479.96M | 0.1% | ▲ Add | 8 | SEC ↗ |
| 36 | Wellington Management ✦ | 6.39M | +2.1% | $479.96M | 0.1% | ▲ Add | 8 | SEC ↗ |
| 37 | Wellington Management ✦ | 6.39M | +2.1% | $479.96M | 0.1% | ▲ Add | 8 | SEC ↗ |
| 38 | Wellington Management ✦ | 6.39M | +2.1% | $479.96M | 0.1% | ▲ Add | 8 | SEC ↗ |
| 39 | Wellington Management ✦ | 6.39M | +2.1% | $479.96M | 0.1% | ▲ Add | 8 | SEC ↗ |
| 40 | Wellington Management ✦ | 6.39M | +2.1% | $479.96M | 0.1% | ▲ Add | 8 | SEC ↗ |
| 41 | Wellington Management ✦ | 6.39M | +2.1% | $479.96M | 0.1% | ▲ Add | 8 | SEC ↗ |
| 42 | Wellington Management ✦ | 6.39M | +2.1% | $479.96M | 0.1% | ▲ Add | 8 | SEC ↗ |
| 43 | Wellington Management ✦ | 6.39M | +2.1% | $479.96M | 0.1% | ▲ Add | 8 | SEC ↗ |
| 44 | Wellington Management ✦ | 6.39M | +2.1% | $479.96M | 0.1% | ▲ Add | 8 | SEC ↗ |
| 45 | Two Sigma Investments ✦ | 5.86M | +120.3% | $439.85M | 0.4% | ▲ Add | 8 | SEC ↗ |
| 46 | Geode Capital Management ✦ (passive) | 3.98M | +26.5% | $305.20M | 0.0% | ▲ Add | 8 | SEC ↗ |
| 47 | Geode Capital Management ✦ (passive) | 3.98M | +26.5% | $305.20M | 0.0% | ▲ Add | 8 | SEC ↗ |
| 48 | State Street Global Advisors ✦ (passive) | 4.00M | +0.5% | $300.03M | 0.0% | ▲ Add | 6 | SEC ↗ |
| 49 | State Street Global Advisors ✦ (passive) | 4.00M | +0.5% | $300.03M | 0.0% | ▲ Add | 6 | SEC ↗ |
| 50 | Royal Bank Of Canada | 3.80M | +239.8% | $285.48M | 0.1% | ▲ Add | 2 | SEC ↗ |
| 51 | Royal Bank Of Canada | 3.80M | +239.8% | $285.48M | 0.1% | ▲ Add | 2 | SEC ↗ |
| 52 | Royal Bank Of Canada | 3.80M | +239.8% | $285.48M | 0.1% | ▲ Add | 2 | SEC ↗ |
| 53 | Royal Bank Of Canada | 3.80M | +239.8% | $285.48M | 0.1% | ▲ Add | 2 | SEC ↗ |
| 54 | Royal Bank Of Canada | 3.80M | +239.8% | $285.48M | 0.1% | ▲ Add | 2 | SEC ↗ |
| 55 | Royal Bank Of Canada | 3.80M | +239.8% | $285.48M | 0.1% | ▲ Add | 2 | SEC ↗ |
| 56 | Royal Bank Of Canada | 3.80M | +239.8% | $285.48M | 0.1% | ▲ Add | 2 | SEC ↗ |
| 57 | Royal Bank Of Canada | 3.80M | +239.8% | $285.48M | 0.1% | ▲ Add | 2 | SEC ↗ |
| 58 | Royal Bank Of Canada | 3.80M | +239.8% | $285.48M | 0.1% | ▲ Add | 2 | SEC ↗ |
| 59 | Royal Bank Of Canada | 3.80M | +239.8% | $285.48M | 0.1% | ▲ Add | 2 | SEC ↗ |
| 60 | Royal Bank Of Canada | 3.80M | +239.8% | $285.48M | 0.1% | ▲ Add | 2 | SEC ↗ |
| 61 | Royal Bank Of Canada | 3.80M | +239.8% | $285.48M | 0.1% | ▲ Add | 2 | SEC ↗ |
| 62 | Royal Bank Of Canada | 3.80M | +239.8% | $285.48M | 0.1% | ▲ Add | 2 | SEC ↗ |
| 63 | Royal Bank Of Canada | 3.80M | +239.8% | $285.48M | 0.1% | ▲ Add | 2 | SEC ↗ |
| 64 | Royal Bank Of Canada | 3.80M | +239.8% | $285.48M | 0.1% | ▲ Add | 2 | SEC ↗ |
| 65 | T. Rowe Price ✦ | 3.03M | +1.2% | $227.17M | 0.0% | ▲ Add | 8 | SEC ↗ |
| 66 | T. Rowe Price ✦ | 3.03M | +1.2% | $227.17M | 0.0% | ▲ Add | 8 | SEC ↗ |
| 67 | JPMorgan Chase ✦ | 2.36M | +2.5% | $171.41M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 68 | JPMorgan Chase ✦ | 2.36M | +2.5% | $171.41M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 69 | JPMorgan Chase ✦ | 2.36M | +2.5% | $171.41M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 70 | JPMorgan Chase ✦ | 2.36M | +2.5% | $171.41M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 71 | JPMorgan Chase ✦ | 2.36M | +2.5% | $171.41M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 72 | JPMorgan Chase ✦ | 2.36M | +2.5% | $171.41M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 73 | JPMorgan Chase ✦ | 2.36M | +2.5% | $171.41M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 74 | JPMorgan Chase ✦ | 2.36M | +2.5% | $171.41M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 75 | JPMorgan Chase ✦ | 2.36M | +2.5% | $171.41M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 76 | JPMorgan Chase ✦ | 2.36M | +2.5% | $171.41M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 77 | JPMorgan Chase ✦ | 2.36M | +2.5% | $171.41M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 78 | Tweedy, Browne ✦ | 2.28M | -7.7% | $170.88M | 13.6% | ▼ Trim | 8 | SEC ↗ |
| 79 | Artisan Partners Limited Partnership | 2.06M | +74.2% | $154.56M | 0.3% | ▲ Add | 2 | SEC ↗ |
| 80 | Goldman Sachs Group ✦ | 1.70M | +98.6% | $127.64M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 81 | Goldman Sachs Group ✦ | 1.70M | +98.6% | $127.64M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 82 | Goldman Sachs Group ✦ | 1.70M | +98.6% | $127.64M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 83 | Goldman Sachs Group ✦ | 1.70M | +98.6% | $127.64M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 84 | Goldman Sachs Group ✦ | 1.70M | +98.6% | $127.64M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 85 | American Century Companies Inc | 1.66M | +2.9% | $124.94M | 0.1% | ▲ Add | 2 | SEC ↗ |
| 86 | Charles Schwab Investment… | 1.58M | +2.7% | $118.89M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 87 | Franklin Resources Inc | 1.58M | +19.2% | $118.27M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 88 | Franklin Resources Inc | 1.58M | +19.2% | $118.27M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 89 | Franklin Resources Inc | 1.58M | +19.2% | $118.27M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 90 | Franklin Resources Inc | 1.58M | +19.2% | $118.27M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 91 | UBS AM, a distinct business unit of… | 1.48M | +6.3% | $110.81M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 92 | UBS AM, a distinct business unit of… | 1.48M | +6.3% | $110.81M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 93 | UBS AM, a distinct business unit of… | 1.48M | +6.3% | $110.81M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 94 | UBS AM, a distinct business unit of… | 1.48M | +6.3% | $110.81M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 95 | UBS AM, a distinct business unit of… | 1.48M | +6.3% | $110.81M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 96 | UBS AM, a distinct business unit of… | 1.48M | +6.3% | $110.81M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 97 | UBS AM, a distinct business unit of… | 1.48M | +6.3% | $110.81M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 98 | UBS AM, a distinct business unit of… | 1.48M | +6.3% | $110.81M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 99 | UBS AM, a distinct business unit of… | 1.48M | +6.3% | $110.81M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 100 | UBS AM, a distinct business unit of… | 1.48M | +6.3% | $110.81M | 0.0% | ▲ Add | 2 | SEC ↗ |
“Their weight” = the position's share of that manager's reported 13F equity value — the conviction measure. ✦ = curated manager.
New buyers
| No new tracked buyers this quarter. |
Exited
| Norges Bank | $25.33M | was 0.0% |
| Balyasny Asset Management L.P. | $9.54M | was 0.0% |
| Healthcare Of Ontario Pension… | $8.70M | was 0.0% |
| Simplex Trading, Llc | $7.65M | was 0.2% |
| Bridgewater Associates | $5.36M | was 0.0% |
| Mariner, LLC | $3.78M | was 0.0% |
| Bank Of Nova Scotia | $331,392 | was 0.0% |
| Clearbridge Investments, LLC | $214,784 | was 0.0% |
| Daiwa Securities Group Inc. | $38,000 | was 0.0% |
Full-market context: across ALL 13F filers (SEC structured data, Q1 2026): 490 holders, 170.17M shares, $11.94B reported. This is a different, older period than the tracked-universe figures above and the two are never mixed.
Frequently co-owned
What else this security's tracked holders most often hold — shared-ownership counts, not fundamental relationships.
Provenance: Ownership from parsed 13F common-stock positions (tracked universe, comparable sets for changes); insider rows from Forms 3/4/5; stakes from Schedules 13D/13G; every filing links to its original on SEC EDGAR.
Reporting period: Q1 2026 ·
Methodology ·
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