证券记录 · 已归档季度
IONS
Ionis Pharmaceuticals, Inc. · Healthcare · Biotechnology
25被追踪持有人
+4Δ持有人
95.56M持有股份
$6.25B报告持仓市值
+5新建仓位
−2清仓
动量输入（同类管理人）：
持有人广度 +19.0% ·
股份流向 -2.3% ·
净新建仓位 +12.0%
· 公式
持有人分散化：持有人数增多，合计持仓比例缩小。
所有持股数据：仅限已追踪的 13F 管理人，普通股持仓，报告期 Q3 2025
持股变化趋势
| 季度 | 持有人 | Δ | 股份 | 报告持仓市值 | 新增 | 清仓 |
|---|---|---|---|---|---|---|
| Q3 2026 | 2 | -1 | 48.54K | $2.16M | n/a | −2 |
| Q2 2026 | 137 | +2 | 148.57M | $11.08B | +6 | −5 |
| Q1 2026 | 139 | -2 | 142.62M | $9.86B | +6 | −9 |
| Q4 2025 | 142 | 0 | 143.10M | $10.36B | +1 | n/a |
| Q3 2025 | 25 | +4 | 95.56M | $6.25B | +5 | −2 |
| Q2 2025 | 19 | +1 | 95.25M | $3.76B | +1 | n/a |
| Q1 2025 | 15 | -1 | 43.90M | $1.32B | +1 | −2 |
| Q4 2024 | 16 | -1 | 43.25M | $1.51B | n/a | −1 |
| Q3 2024 | 16 | -1 | 34.86M | $1.40B | n/a | −1 |
| Q2 2024 | 17 | n/a | 24.68M | $1.18B | n/a | n/a |
持有人 · Q3 2025
| # | 管理人 | 股份 | Δ股份 | 价值 | 其权重 | 持有 | ||
|---|---|---|---|---|---|---|---|---|
| 1 | Fidelity (FMR) ✦ | 23.69M | +0.2% | $1.55B | 0.1% | ▲ Add | 2 | SEC ↗ ×6 |
| 2 | The Vanguard Group ✦ (被动) | 16.48M | -1.4% | $1.08B | 0.0% | ▼ Trim | 2 | SEC ↗ ×5 |
| 3 | Capital World Investors ✦ | 12.72M | +1.5% | $832.32M | 0.1% | ▲ Add | 6 | SEC ↗ |
| 4 | BlackRock ✦ (被动) | 10.45M | -4.1% | $683.50M | 0.0% | ▼ Trim | 2 | SEC ↗ ×24 |
| 5 | Wellington Management ✦ | 6.59M | +3.8% | $431.04M | 0.1% | ▲ Add | 6 | SEC ↗ ×12 |
| 6 | State Street Global Advisors ✦ (被动) | 4.39M | -3.1% | $287.11M | 0.0% | ▼ Trim | 4 | SEC ↗ ×3 |
| 7 | Geode Capital Management ✦ (被动) | 3.07M | +6.1% | $200.63M | 0.0% | ▲ Add | 6 | SEC ↗ ×2 |
| 8 | Tweedy, Browne ✦ | 2.90M | +0.3% | $189.80M | 16.5% | ▲ Add | 6 | SEC ↗ |
| 9 | T. Rowe Price ✦ | 2.73M | -12.7% | $178.58M | 0.0% | ▼ Trim | 6 | SEC ↗ ×2 |
| 10 | Citadel Advisors ✦ | 2.40M | +60.7% | $157.14M | 0.1% | ▲ Add | 6 | SEC ↗ ×2 |
| 11 | Two Sigma Investments ✦ | 1.58M | -11.9% | $103.10M | 0.2% | ▼ Trim | 6 | SEC ↗ |
| 12 | Adage Capital Partners ✦ | 1.31M | -65.4% | $86.03M | 0.1% | ▼ Trim | 6 | SEC ↗ |
| 13 | Morgan Stanley ✦ | 1.18M | n/a | $77.22M | 0.0% | n/c | 1 | SEC ↗ ×17 |
| 14 | JPMorgan Chase ✦ | 1.09M | n/a | $71.24M | 0.0% | n/c | 1 | SEC ↗ ×24 |
| 15 | Marshall Wace ✦ | 958.83K | +7219.3% | $62.73M | 0.1% | ▲ Add | 6 | SEC ↗ ×3 |
| 16 | Millennium Management ✦ | 779.57K | -70.6% | $51.00M | 0.0% | ▼ Trim | 6 | SEC ↗ |
| 17 | Goldman Sachs Group ✦ | 777.57K | n/a | $50.87M | 0.0% | n/c | 1 | SEC ↗ ×4 |
| 18 | ARK Investment Management ✦ | 631.22K | -29.9% | $41.29M | 0.2% | ▼ Trim | 6 | SEC ↗ |
| 19 | D. E. Shaw & Co. ✦ | 630.94K | 新增 | $41.28M | 0.0% | New | 1 | SEC ↗ ×3 |
| 20 | Arrowstreet Capital ✦ | 630.14K | 新增 | $41.22M | 0.0% | New | 1 | SEC ↗ |
| 21 | Renaissance Technologies ✦ | 486.71K | +79.8% | $31.84M | 0.0% | ▲ Add | 6 | SEC ↗ |
| 22 | Bridgewater Associates ✦ | 43.58K | 新增 | $2.85M | 0.0% | New | 1 | SEC ↗ |
| 23 | Gotham Asset Management ✦ | 32.15K | +125.2% | $2.10M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 24 | AQR Capital Management ✦ | 6.82K | 新增 | $438,749 | 0.0% | New | 1 | SEC ↗ ×4 |
| 25 | Fisher Asset Management ✦ | 6.21K | 新增 | $406,258 | 0.0% | New | 1 | SEC ↗ |
"持仓权重"指该仓位占该管理人13F申报股票组合市值的比例，即持仓信心指标。✦ = 精选管理人。
新增买入方
| D. E. Shaw & Co. | $41.28M | 0.0% |
| Arrowstreet Capital | $41.22M | 0.0% |
| Bridgewater Associates | $2.85M | 0.0% |
| AQR Capital Management | $438,749 | 0.0% |
| Fisher Asset Management | $406,258 | 0.0% |
已清仓
| Norges Bank | $17.79M | 曾为 0.0% |
| Point72 Asset Management | $11.56M | 曾为 0.0% |
全市场背景: 涵盖所有13F申报机构（SEC结构化数据， Q1 2026): 490 持有人, 170.17M 股份, $11.94B 已申报. 这是与上方被追踪全域数据不同的较早期间，两者从不混用。
常见共同持仓
持有该证券的受追踪机构最常同时持有的其他证券：基于共同持有计数，而非基本面关联。
公开市场买入 (P)
在我们的覆盖窗口内无内部人士公开市场买入记录。
公开市场卖出 (S)
Oct 16
Devers Shannon L.
Officer · 1.36K 股 · $59,082
Oct 16
Swayze Eric
Officer · 53 股 · $2,308
授予、行权及税务代扣代缴在本平台均不计入买入或卖出。 方法论
数据来源: 持股数据来源于已解析的13F普通股持仓（被追踪范围，变动对比集）；内部人行为来自Form 3/4/5；重大持股来自Schedule 13D/13G；所有文件均链接至SEC EDGAR原始申报。
报告期: Q3 2025 ·
方法论 ·
通过API获取此数据