Security record · archived quarter
IONS
Ionis Pharmaceuticals, Inc. · Healthcare · Biotechnology
25Tracked holders
+4Δ holders
95.56MShares held
$6.25BReported value
+5New positions
−2Exits
Momentum inputs (comparable managers):
holder breadth +19.0% ·
share flow -2.3% ·
net new positions +12.0%
— formula
Ownership fragmentation — more holders, smaller aggregate stake
All ownership figures: tracked 13F managers only, common-stock positions, reporting period Q3 2025
Ownership over time
| Quarter | Holders | Δ | Shares | Reported value | New | Exits |
|---|---|---|---|---|---|---|
| Q2 2026 | 139 | +2 | 148.59M | $11.08B | +6 | −3 |
| Q1 2026 | 139 | -2 | 142.62M | $9.86B | +6 | −9 |
| Q4 2025 | 142 | 0 | 143.10M | $10.36B | +1 | — |
| Q3 2025 | 25 | +4 | 95.56M | $6.25B | +5 | −2 |
| Q2 2025 | 19 | +1 | 95.25M | $3.76B | +1 | — |
| Q1 2025 | 15 | -1 | 43.90M | $1.32B | +1 | −2 |
| Q4 2024 | 16 | -1 | 43.25M | $1.51B | — | −1 |
| Q3 2024 | 16 | -1 | 34.86M | $1.40B | — | −1 |
| Q2 2024 | 17 | — | 24.68M | $1.18B | — | — |
Who holds it · Q3 2025
| # | Manager | Shares | Δ shares | Value | Their weight | Held | ||
|---|---|---|---|---|---|---|---|---|
| 1 | Fidelity (FMR) ✦ | 23.69M | +0.2% | $1.55B | 0.1% | ▲ Add | 2 | SEC ↗ |
| 2 | Fidelity (FMR) ✦ | 23.69M | +0.2% | $1.55B | 0.1% | ▲ Add | 2 | SEC ↗ |
| 3 | Fidelity (FMR) ✦ | 23.69M | +0.2% | $1.55B | 0.1% | ▲ Add | 2 | SEC ↗ |
| 4 | Fidelity (FMR) ✦ | 23.69M | +0.2% | $1.55B | 0.1% | ▲ Add | 2 | SEC ↗ |
| 5 | Fidelity (FMR) ✦ | 23.69M | +0.2% | $1.55B | 0.1% | ▲ Add | 2 | SEC ↗ |
| 6 | Fidelity (FMR) ✦ | 23.69M | +0.2% | $1.55B | 0.1% | ▲ Add | 2 | SEC ↗ |
| 7 | The Vanguard Group ✦ (passive) | 16.48M | -1.4% | $1.08B | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 8 | The Vanguard Group ✦ (passive) | 16.48M | -1.4% | $1.08B | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 9 | The Vanguard Group ✦ (passive) | 16.48M | -1.4% | $1.08B | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 10 | The Vanguard Group ✦ (passive) | 16.48M | -1.4% | $1.08B | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 11 | The Vanguard Group ✦ (passive) | 16.48M | -1.4% | $1.08B | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 12 | Capital World Investors ✦ | 12.72M | +1.5% | $832.32M | 0.1% | ▲ Add | 6 | SEC ↗ |
| 13 | BlackRock ✦ (passive) | 10.45M | -4.1% | $683.50M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 14 | BlackRock ✦ (passive) | 10.45M | -4.1% | $683.50M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 15 | BlackRock ✦ (passive) | 10.45M | -4.1% | $683.50M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 16 | BlackRock ✦ (passive) | 10.45M | -4.1% | $683.50M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 17 | BlackRock ✦ (passive) | 10.45M | -4.1% | $683.50M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 18 | BlackRock ✦ (passive) | 10.45M | -4.1% | $683.50M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 19 | BlackRock ✦ (passive) | 10.45M | -4.1% | $683.50M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 20 | BlackRock ✦ (passive) | 10.45M | -4.1% | $683.50M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 21 | BlackRock ✦ (passive) | 10.45M | -4.1% | $683.50M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 22 | BlackRock ✦ (passive) | 10.45M | -4.1% | $683.50M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 23 | BlackRock ✦ (passive) | 10.45M | -4.1% | $683.50M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 24 | BlackRock ✦ (passive) | 10.45M | -4.1% | $683.50M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 25 | BlackRock ✦ (passive) | 10.45M | -4.1% | $683.50M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 26 | BlackRock ✦ (passive) | 10.45M | -4.1% | $683.50M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 27 | BlackRock ✦ (passive) | 10.45M | -4.1% | $683.50M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 28 | BlackRock ✦ (passive) | 10.45M | -4.1% | $683.50M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 29 | BlackRock ✦ (passive) | 10.45M | -4.1% | $683.50M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 30 | BlackRock ✦ (passive) | 10.45M | -4.1% | $683.50M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 31 | BlackRock ✦ (passive) | 10.45M | -4.1% | $683.50M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 32 | BlackRock ✦ (passive) | 10.45M | -4.1% | $683.50M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 33 | BlackRock ✦ (passive) | 10.45M | -4.1% | $683.50M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 34 | BlackRock ✦ (passive) | 10.45M | -4.1% | $683.50M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 35 | BlackRock ✦ (passive) | 10.45M | -4.1% | $683.50M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 36 | BlackRock ✦ (passive) | 10.45M | -4.1% | $683.50M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 37 | Wellington Management ✦ | 6.59M | +3.8% | $431.04M | 0.1% | ▲ Add | 6 | SEC ↗ |
| 38 | Wellington Management ✦ | 6.59M | +3.8% | $431.04M | 0.1% | ▲ Add | 6 | SEC ↗ |
| 39 | Wellington Management ✦ | 6.59M | +3.8% | $431.04M | 0.1% | ▲ Add | 6 | SEC ↗ |
| 40 | Wellington Management ✦ | 6.59M | +3.8% | $431.04M | 0.1% | ▲ Add | 6 | SEC ↗ |
| 41 | Wellington Management ✦ | 6.59M | +3.8% | $431.04M | 0.1% | ▲ Add | 6 | SEC ↗ |
| 42 | Wellington Management ✦ | 6.59M | +3.8% | $431.04M | 0.1% | ▲ Add | 6 | SEC ↗ |
| 43 | Wellington Management ✦ | 6.59M | +3.8% | $431.04M | 0.1% | ▲ Add | 6 | SEC ↗ |
| 44 | Wellington Management ✦ | 6.59M | +3.8% | $431.04M | 0.1% | ▲ Add | 6 | SEC ↗ |
| 45 | Wellington Management ✦ | 6.59M | +3.8% | $431.04M | 0.1% | ▲ Add | 6 | SEC ↗ |
| 46 | Wellington Management ✦ | 6.59M | +3.8% | $431.04M | 0.1% | ▲ Add | 6 | SEC ↗ |
| 47 | Wellington Management ✦ | 6.59M | +3.8% | $431.04M | 0.1% | ▲ Add | 6 | SEC ↗ |
| 48 | Wellington Management ✦ | 6.59M | +3.8% | $431.04M | 0.1% | ▲ Add | 6 | SEC ↗ |
| 49 | State Street Global Advisors ✦ (passive) | 4.39M | -3.1% | $287.11M | 0.0% | ▼ Trim | 4 | SEC ↗ |
| 50 | State Street Global Advisors ✦ (passive) | 4.39M | -3.1% | $287.11M | 0.0% | ▼ Trim | 4 | SEC ↗ |
| 51 | State Street Global Advisors ✦ (passive) | 4.39M | -3.1% | $287.11M | 0.0% | ▼ Trim | 4 | SEC ↗ |
| 52 | Geode Capital Management ✦ (passive) | 3.07M | +6.1% | $200.63M | 0.0% | ▲ Add | 6 | SEC ↗ |
| 53 | Geode Capital Management ✦ (passive) | 3.07M | +6.1% | $200.63M | 0.0% | ▲ Add | 6 | SEC ↗ |
| 54 | Tweedy, Browne ✦ | 2.90M | +0.3% | $189.80M | 16.5% | ▲ Add | 6 | SEC ↗ |
| 55 | T. Rowe Price ✦ | 2.73M | -12.7% | $178.58M | 0.0% | ▼ Trim | 6 | SEC ↗ |
| 56 | T. Rowe Price ✦ | 2.73M | -12.7% | $178.58M | 0.0% | ▼ Trim | 6 | SEC ↗ |
| 57 | Citadel Advisors ✦ | 2.40M | +60.7% | $157.14M | 0.1% | ▲ Add | 6 | SEC ↗ |
| 58 | Citadel Advisors ✦ | 2.40M | +60.7% | $157.14M | 0.1% | ▲ Add | 6 | SEC ↗ |
| 59 | Two Sigma Investments ✦ | 1.58M | -11.9% | $103.10M | 0.2% | ▼ Trim | 6 | SEC ↗ |
| 60 | Adage Capital Partners ✦ | 1.31M | -65.4% | $86.03M | 0.1% | ▼ Trim | 6 | SEC ↗ |
| 61 | Morgan Stanley ✦ | 1.18M | — | $77.22M | 0.0% | n/c | 1 | SEC ↗ |
| 62 | Morgan Stanley ✦ | 1.18M | — | $77.22M | 0.0% | n/c | 1 | SEC ↗ |
| 63 | Morgan Stanley ✦ | 1.18M | — | $77.22M | 0.0% | n/c | 1 | SEC ↗ |
| 64 | Morgan Stanley ✦ | 1.18M | — | $77.22M | 0.0% | n/c | 1 | SEC ↗ |
| 65 | Morgan Stanley ✦ | 1.18M | — | $77.22M | 0.0% | n/c | 1 | SEC ↗ |
| 66 | Morgan Stanley ✦ | 1.18M | — | $77.22M | 0.0% | n/c | 1 | SEC ↗ |
| 67 | Morgan Stanley ✦ | 1.18M | — | $77.22M | 0.0% | n/c | 1 | SEC ↗ |
| 68 | Morgan Stanley ✦ | 1.18M | — | $77.22M | 0.0% | n/c | 1 | SEC ↗ |
| 69 | Morgan Stanley ✦ | 1.18M | — | $77.22M | 0.0% | n/c | 1 | SEC ↗ |
| 70 | Morgan Stanley ✦ | 1.18M | — | $77.22M | 0.0% | n/c | 1 | SEC ↗ |
| 71 | Morgan Stanley ✦ | 1.18M | — | $77.22M | 0.0% | n/c | 1 | SEC ↗ |
| 72 | Morgan Stanley ✦ | 1.18M | — | $77.22M | 0.0% | n/c | 1 | SEC ↗ |
| 73 | Morgan Stanley ✦ | 1.18M | — | $77.22M | 0.0% | n/c | 1 | SEC ↗ |
| 74 | Morgan Stanley ✦ | 1.18M | — | $77.22M | 0.0% | n/c | 1 | SEC ↗ |
| 75 | Morgan Stanley ✦ | 1.18M | — | $77.22M | 0.0% | n/c | 1 | SEC ↗ |
| 76 | Morgan Stanley ✦ | 1.18M | — | $77.22M | 0.0% | n/c | 1 | SEC ↗ |
| 77 | Morgan Stanley ✦ | 1.18M | — | $77.22M | 0.0% | n/c | 1 | SEC ↗ |
| 78 | JPMorgan Chase ✦ | 1.09M | — | $71.24M | 0.0% | n/c | 1 | SEC ↗ |
| 79 | JPMorgan Chase ✦ | 1.09M | — | $71.24M | 0.0% | n/c | 1 | SEC ↗ |
| 80 | JPMorgan Chase ✦ | 1.09M | — | $71.24M | 0.0% | n/c | 1 | SEC ↗ |
| 81 | JPMorgan Chase ✦ | 1.09M | — | $71.24M | 0.0% | n/c | 1 | SEC ↗ |
| 82 | JPMorgan Chase ✦ | 1.09M | — | $71.24M | 0.0% | n/c | 1 | SEC ↗ |
| 83 | JPMorgan Chase ✦ | 1.09M | — | $71.24M | 0.0% | n/c | 1 | SEC ↗ |
| 84 | JPMorgan Chase ✦ | 1.09M | — | $71.24M | 0.0% | n/c | 1 | SEC ↗ |
| 85 | JPMorgan Chase ✦ | 1.09M | — | $71.24M | 0.0% | n/c | 1 | SEC ↗ |
| 86 | JPMorgan Chase ✦ | 1.09M | — | $71.24M | 0.0% | n/c | 1 | SEC ↗ |
| 87 | JPMorgan Chase ✦ | 1.09M | — | $71.24M | 0.0% | n/c | 1 | SEC ↗ |
| 88 | JPMorgan Chase ✦ | 1.09M | — | $71.24M | 0.0% | n/c | 1 | SEC ↗ |
| 89 | JPMorgan Chase ✦ | 1.09M | — | $71.24M | 0.0% | n/c | 1 | SEC ↗ |
| 90 | JPMorgan Chase ✦ | 1.09M | — | $71.24M | 0.0% | n/c | 1 | SEC ↗ |
| 91 | JPMorgan Chase ✦ | 1.09M | — | $71.24M | 0.0% | n/c | 1 | SEC ↗ |
| 92 | JPMorgan Chase ✦ | 1.09M | — | $71.24M | 0.0% | n/c | 1 | SEC ↗ |
| 93 | JPMorgan Chase ✦ | 1.09M | — | $71.24M | 0.0% | n/c | 1 | SEC ↗ |
| 94 | JPMorgan Chase ✦ | 1.09M | — | $71.24M | 0.0% | n/c | 1 | SEC ↗ |
| 95 | JPMorgan Chase ✦ | 1.09M | — | $71.24M | 0.0% | n/c | 1 | SEC ↗ |
| 96 | JPMorgan Chase ✦ | 1.09M | — | $71.24M | 0.0% | n/c | 1 | SEC ↗ |
| 97 | JPMorgan Chase ✦ | 1.09M | — | $71.24M | 0.0% | n/c | 1 | SEC ↗ |
| 98 | JPMorgan Chase ✦ | 1.09M | — | $71.24M | 0.0% | n/c | 1 | SEC ↗ |
| 99 | JPMorgan Chase ✦ | 1.09M | — | $71.24M | 0.0% | n/c | 1 | SEC ↗ |
| 100 | JPMorgan Chase ✦ | 1.09M | — | $71.24M | 0.0% | n/c | 1 | SEC ↗ |
“Their weight” = the position's share of that manager's reported 13F equity value — the conviction measure. ✦ = curated manager.
New buyers
| No new tracked buyers this quarter. |
Exited
| Norges Bank | $17.79M | was 0.0% |
| Point72 Asset Management | $11.56M | was 0.0% |
Full-market context: across ALL 13F filers (SEC structured data, Q1 2026): 490 holders, 170.17M shares, $11.94B reported. This is a different, older period than the tracked-universe figures above and the two are never mixed.
Frequently co-owned
What else this security's tracked holders most often hold — shared-ownership counts, not fundamental relationships.
Provenance: Ownership from parsed 13F common-stock positions (tracked universe, comparable sets for changes); insider rows from Forms 3/4/5; stakes from Schedules 13D/13G; every filing links to its original on SEC EDGAR.
Reporting period: Q3 2025 ·
Methodology ·
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