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Security record · archived quarter

IONS

Ionis Pharmaceuticals, Inc. · Healthcare · Biotechnology

63.57 +2.5% mkt cap $10.56B quote delayed (FMP) · as of Aug 25 22:08 UTC — separate from filing data below

Q2 2026 Q1 2026 Q4 2025 Q3 2025 Q2 2025 Q1 2025 Q4 2024 Q3 2024
19Tracked holders
+1Δ holders
95.25MShares held
$3.76BReported value
+1New positions
−0Exits
Rising Conviction score 58/100 4 quarters of rising tracked shares ●●●●○○ How these are computed → Explain this at the Research Desk →

Momentum inputs (comparable managers): holder breadth +5.6% · share flow +0.1% · net new positions +5.3%formula
Broad accumulation — rising shares across more holders

All ownership figures: tracked 13F managers only, common-stock positions, reporting period Q2 2025

Ownership over time
QuarterHoldersΔSharesReported valueNewExits
Q2 2026 139 +2 148.59M $11.08B +6 −3
Q1 2026 139 -2 142.62M $9.86B +6 −9
Q4 2025 142 0 143.10M $10.36B +1
Q3 2025 25 +4 95.56M $6.25B +5 −2
Q2 2025 19 +1 95.25M $3.76B +1
Q1 2025 15 -1 43.90M $1.32B +1 −2
Q4 2024 16 -1 43.25M $1.51B −1
Q3 2024 16 -1 34.86M $1.40B −1
Q2 2024 17 24.68M $1.18B
Holder count
Who holds it · Q2 2025
#ManagerSharesΔ sharesValueTheir weightHeld
1 Fidelity (FMR) 23.64M $934.13M 0.1% n/c 1 SEC ↗
2 Fidelity (FMR) 23.64M $934.13M 0.1% n/c 1 SEC ↗
3 Fidelity (FMR) 23.64M $934.13M 0.1% n/c 1 SEC ↗
4 Fidelity (FMR) 23.64M $934.13M 0.1% n/c 1 SEC ↗
5 Fidelity (FMR) 23.64M $934.13M 0.1% n/c 1 SEC ↗
6 Fidelity (FMR) 23.64M $934.13M 0.1% n/c 1 SEC ↗
7 The Vanguard Group (passive) 16.71M $660.40M 0.0% n/c 1 SEC ↗
8 The Vanguard Group (passive) 16.71M $660.40M 0.0% n/c 1 SEC ↗
9 The Vanguard Group (passive) 16.71M $660.40M 0.0% n/c 1 SEC ↗
10 The Vanguard Group (passive) 16.71M $660.40M 0.0% n/c 1 SEC ↗
11 The Vanguard Group (passive) 16.71M $660.40M 0.0% n/c 1 SEC ↗
12 Capital World Investors 12.54M +1.4% $495.46M 0.1% ▲ Add 5 SEC ↗
13 BlackRock (passive) 10.90M $430.54M 0.0% n/c 1 SEC ↗
14 BlackRock (passive) 10.90M $430.54M 0.0% n/c 1 SEC ↗
15 BlackRock (passive) 10.90M $430.54M 0.0% n/c 1 SEC ↗
16 BlackRock (passive) 10.90M $430.54M 0.0% n/c 1 SEC ↗
17 BlackRock (passive) 10.90M $430.54M 0.0% n/c 1 SEC ↗
18 BlackRock (passive) 10.90M $430.54M 0.0% n/c 1 SEC ↗
19 BlackRock (passive) 10.90M $430.54M 0.0% n/c 1 SEC ↗
20 BlackRock (passive) 10.90M $430.54M 0.0% n/c 1 SEC ↗
21 BlackRock (passive) 10.90M $430.54M 0.0% n/c 1 SEC ↗
22 BlackRock (passive) 10.90M $430.54M 0.0% n/c 1 SEC ↗
23 BlackRock (passive) 10.90M $430.54M 0.0% n/c 1 SEC ↗
24 BlackRock (passive) 10.90M $430.54M 0.0% n/c 1 SEC ↗
25 BlackRock (passive) 10.90M $430.54M 0.0% n/c 1 SEC ↗
26 BlackRock (passive) 10.90M $430.54M 0.0% n/c 1 SEC ↗
27 BlackRock (passive) 10.90M $430.54M 0.0% n/c 1 SEC ↗
28 BlackRock (passive) 10.90M $430.54M 0.0% n/c 1 SEC ↗
29 BlackRock (passive) 10.90M $430.54M 0.0% n/c 1 SEC ↗
30 BlackRock (passive) 10.90M $430.54M 0.0% n/c 1 SEC ↗
31 BlackRock (passive) 10.90M $430.54M 0.0% n/c 1 SEC ↗
32 BlackRock (passive) 10.90M $430.54M 0.0% n/c 1 SEC ↗
33 BlackRock (passive) 10.90M $430.54M 0.0% n/c 1 SEC ↗
34 BlackRock (passive) 10.90M $430.54M 0.0% n/c 1 SEC ↗
35 BlackRock (passive) 10.90M $430.54M 0.0% n/c 1 SEC ↗
36 Wellington Management 6.35M -24.6% $250.72M 0.0% ▼ Trim 5 SEC ↗
37 Wellington Management 6.35M -24.6% $250.72M 0.0% ▼ Trim 5 SEC ↗
38 Wellington Management 6.35M -24.6% $250.72M 0.0% ▼ Trim 5 SEC ↗
39 Wellington Management 6.35M -24.6% $250.72M 0.0% ▼ Trim 5 SEC ↗
40 Wellington Management 6.35M -24.6% $250.72M 0.0% ▼ Trim 5 SEC ↗
41 Wellington Management 6.35M -24.6% $250.72M 0.0% ▼ Trim 5 SEC ↗
42 Wellington Management 6.35M -24.6% $250.72M 0.0% ▼ Trim 5 SEC ↗
43 Wellington Management 6.35M -24.6% $250.72M 0.0% ▼ Trim 5 SEC ↗
44 Wellington Management 6.35M -24.6% $250.72M 0.0% ▼ Trim 5 SEC ↗
45 State Street Global Advisors (passive) 4.53M -6.5% $179.00M 0.0% ▼ Trim 3 SEC ↗
46 State Street Global Advisors (passive) 4.53M -6.5% $179.00M 0.0% ▼ Trim 3 SEC ↗
47 State Street Global Advisors (passive) 4.53M -6.5% $179.00M 0.0% ▼ Trim 3 SEC ↗
48 Adage Capital Partners 3.80M +253.3% $150.14M 0.3% ▲ Add 5 SEC ↗
49 T. Rowe Price 3.13M -4.3% $123.51M 0.0% ▼ Trim 5 SEC ↗
50 T. Rowe Price 3.13M -4.3% $123.51M 0.0% ▼ Trim 5 SEC ↗
51 Tweedy, Browne 2.89M -3.1% $114.26M 10.6% ▼ Trim 5 SEC ↗
52 Geode Capital Management (passive) 2.89M +1.7% $114.25M 0.0% ▲ Add 5 SEC ↗
53 Geode Capital Management (passive) 2.89M +1.7% $114.25M 0.0% ▲ Add 5 SEC ↗
54 Millennium Management 2.65M +317.0% $104.68M 0.1% ▲ Add 5 SEC ↗
55 Two Sigma Investments 1.79M +6.1% $70.66M 0.1% ▲ Add 5 SEC ↗
56 Citadel Advisors 1.49M -57.0% $59.07M 0.1% ▼ Trim 5 SEC ↗
57 Citadel Advisors 1.49M -57.0% $59.07M 0.1% ▼ Trim 5 SEC ↗
58 ARK Investment Management 900.32K -10.0% $35.57M 0.3% ▼ Trim 5 SEC ↗
59 Norges Bank (passive) 450.25K -47.5% $17.79M 0.0% ▼ Trim 5 SEC ↗
60 Point72 Asset Management 292.65K +1.9% $11.56M 0.0% ▲ Add 2 SEC ↗
61 Renaissance Technologies 270.71K +76.3% $10.70M 0.0% ▲ Add 5 SEC ↗
62 Gotham Asset Management 14.28K New $564,163 0.0% New 1 SEC ↗
63 Marshall Wace 13.10K +43.9% $517,581 0.0% ▲ Add 5 SEC ↗
64 Marshall Wace 13.10K +43.9% $517,581 0.0% ▲ Add 5 SEC ↗

“Their weight” = the position's share of that manager's reported 13F equity value — the conviction measure. ✦ = curated manager.

New buyers

Gotham Asset Management $564,163 0.0%

Exited

No tracked exits this quarter.

Full-market context: across ALL 13F filers (SEC structured data, Q1 2026): 490 holders, 170.17M shares, $11.94B reported. This is a different, older period than the tracked-universe figures above and the two are never mixed.

Frequently co-owned

What else this security's tracked holders most often hold — shared-ownership counts, not fundamental relationships.

Provenance: Ownership from parsed 13F common-stock positions (tracked universe, comparable sets for changes); insider rows from Forms 3/4/5; stakes from Schedules 13D/13G; every filing links to its original on SEC EDGAR. Reporting period: Q2 2025 · Methodology · Get this via the API