IONS
Ionis Pharmaceuticals, Inc. · Healthcare · Biotechnology
Momentum inputs (comparable managers):
holder breadth +5.6% ·
share flow +0.1% ·
net new positions +5.3%
· formula
Broad accumulation: rising shares across more holders
All ownership figures: tracked 13F managers only, common-stock positions, reporting period Q2 2025
| Quarter | Holders | Δ | Shares | Reported value | New | Exits |
|---|---|---|---|---|---|---|
| Q2 2026 | 137 | +2 | 148.57M | $11.08B | +6 | −5 |
| Q1 2026 | 139 | -2 | 142.62M | $9.86B | +6 | −9 |
| Q4 2025 | 142 | 0 | 143.10M | $10.36B | +1 | n/a |
| Q3 2025 | 25 | +4 | 95.56M | $6.25B | +5 | −2 |
| Q2 2025 | 19 | +1 | 95.25M | $3.76B | +1 | n/a |
| Q1 2025 | 15 | -1 | 43.90M | $1.32B | +1 | −2 |
| Q4 2024 | 16 | -1 | 43.25M | $1.51B | n/a | −1 |
| Q3 2024 | 16 | -1 | 34.86M | $1.40B | n/a | −1 |
| Q2 2024 | 17 | n/a | 24.68M | $1.18B | n/a | n/a |
| # | Manager | Shares | Δ shares | Value | Their weight | Held | ||
|---|---|---|---|---|---|---|---|---|
| 1 | Fidelity (FMR) ✦ | 23.64M | n/a | $934.13M | 0.1% | n/c | 1 | SEC ↗ ×6 |
| 2 | The Vanguard Group ✦ (passive) | 16.71M | n/a | $660.40M | 0.0% | n/c | 1 | SEC ↗ ×5 |
| 3 | Capital World Investors ✦ | 12.54M | +1.4% | $495.46M | 0.1% | ▲ Add | 5 | SEC ↗ |
| 4 | BlackRock ✦ (passive) | 10.90M | n/a | $430.54M | 0.0% | n/c | 1 | SEC ↗ ×23 |
| 5 | Wellington Management ✦ | 6.35M | -24.6% | $250.72M | 0.0% | ▼ Trim | 5 | SEC ↗ ×9 |
| 6 | State Street Global Advisors ✦ (passive) | 4.53M | -6.5% | $179.00M | 0.0% | ▼ Trim | 3 | SEC ↗ ×3 |
| 7 | Adage Capital Partners ✦ | 3.80M | +253.3% | $150.14M | 0.3% | ▲ Add | 5 | SEC ↗ |
| 8 | T. Rowe Price ✦ | 3.13M | -4.3% | $123.51M | 0.0% | ▼ Trim | 5 | SEC ↗ ×2 |
| 9 | Tweedy, Browne ✦ | 2.89M | -3.1% | $114.26M | 10.6% | ▼ Trim | 5 | SEC ↗ |
| 10 | Geode Capital Management ✦ (passive) | 2.89M | +1.7% | $114.25M | 0.0% | ▲ Add | 5 | SEC ↗ ×2 |
| 11 | Millennium Management ✦ | 2.65M | +317.0% | $104.68M | 0.1% | ▲ Add | 5 | SEC ↗ |
| 12 | Two Sigma Investments ✦ | 1.79M | +6.1% | $70.66M | 0.1% | ▲ Add | 5 | SEC ↗ |
| 13 | Citadel Advisors ✦ | 1.49M | -57.0% | $59.07M | 0.1% | ▼ Trim | 5 | SEC ↗ ×2 |
| 14 | ARK Investment Management ✦ | 900.32K | -10.0% | $35.57M | 0.3% | ▼ Trim | 5 | SEC ↗ |
| 15 | Norges Bank ✦ (passive) | 450.25K | -47.5% | $17.79M | 0.0% | ▼ Trim | 5 | SEC ↗ |
| 16 | Point72 Asset Management ✦ | 292.65K | +1.9% | $11.56M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 17 | Renaissance Technologies ✦ | 270.71K | +76.3% | $10.70M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 18 | Gotham Asset Management ✦ | 14.28K | New | $564,163 | 0.0% | New | 1 | SEC ↗ |
| 19 | Marshall Wace ✦ | 13.10K | +43.9% | $517,581 | 0.0% | ▲ Add | 5 | SEC ↗ ×2 |
“Their weight” = the position's share of that manager's reported 13F equity value: the conviction measure. ✦ = curated manager.
New buyers
| Gotham Asset Management | $564,163 | 0.0% |
Exited
| No tracked exits this quarter. |
Full-market context: across ALL 13F filers (SEC structured data, Q1 2026): 490 holders, 170.17M shares, $11.94B reported. This is a different, older period than the tracked-universe figures above and the two are never mixed.
What else this security's tracked holders most often hold: shared-ownership counts, not fundamental relationships.