证券记录 · 已归档季度
IONS
Ionis Pharmaceuticals, Inc. · Healthcare · Biotechnology
16被追踪持有人
-1Δ持有人
43.25M持有股份
$1.51B报告持仓市值
+0新建仓位
−1清仓
动量输入（同类管理人）：
持有人广度 -5.9% ·
股份流向 +7.4% ·
净新建仓位 -6.2%
— 公式
集中积累 — 持股数量上升但持有人减少
所有持股数据：仅限已追踪的 13F 管理人，普通股持仓，报告期 Q4 2024
持股变化趋势
| 季度 | 持有人 | Δ | 股份 | 报告持仓市值 | 新增 | 清仓 |
|---|---|---|---|---|---|---|
| Q2 2026 | 139 | +2 | 148.59M | $11.08B | +6 | −3 |
| Q1 2026 | 139 | -2 | 142.62M | $9.86B | +6 | −9 |
| Q4 2025 | 142 | 0 | 143.10M | $10.36B | +1 | — |
| Q3 2025 | 25 | +4 | 95.56M | $6.25B | +5 | −2 |
| Q2 2025 | 19 | +1 | 95.25M | $3.76B | +1 | — |
| Q1 2025 | 15 | -1 | 43.90M | $1.32B | +1 | −2 |
| Q4 2024 | 16 | -1 | 43.25M | $1.51B | — | −1 |
| Q3 2024 | 16 | -1 | 34.86M | $1.40B | — | −1 |
| Q2 2024 | 17 | — | 24.68M | $1.18B | — | — |
持有人 · Q4 2024
| # | 管理人 | 股份 | Δ股份 | 价值 | 其权重 | 持有 | ||
|---|---|---|---|---|---|---|---|---|
| 1 | Capital World Investors ✦ | 11.47M | +46.5% | $400.83M | 0.1% | ▲ Add | 3 | SEC ↗ |
| 2 | Wellington Management ✦ | 8.67M | -0.7% | $303.18M | 0.1% | ▼ Trim | 3 | SEC ↗ |
| 3 | Wellington Management ✦ | 8.67M | -0.7% | $303.18M | 0.1% | ▼ Trim | 3 | SEC ↗ |
| 4 | Wellington Management ✦ | 8.67M | -0.7% | $303.18M | 0.1% | ▼ Trim | 3 | SEC ↗ |
| 5 | Wellington Management ✦ | 8.67M | -0.7% | $303.18M | 0.1% | ▼ Trim | 3 | SEC ↗ |
| 6 | Wellington Management ✦ | 8.67M | -0.7% | $303.18M | 0.1% | ▼ Trim | 3 | SEC ↗ |
| 7 | Wellington Management ✦ | 8.67M | -0.7% | $303.18M | 0.1% | ▼ Trim | 3 | SEC ↗ |
| 8 | Wellington Management ✦ | 8.67M | -0.7% | $303.18M | 0.1% | ▼ Trim | 3 | SEC ↗ |
| 9 | Wellington Management ✦ | 8.67M | -0.7% | $303.18M | 0.1% | ▼ Trim | 3 | SEC ↗ |
| 10 | Wellington Management ✦ | 8.67M | -0.7% | $303.18M | 0.1% | ▼ Trim | 3 | SEC ↗ |
| 11 | State Street Global Advisors ✦ (被动) | 5.43M | — | $189.71M | 0.0% | n/c | 1 | SEC ↗ |
| 12 | State Street Global Advisors ✦ (被动) | 5.43M | — | $189.71M | 0.0% | n/c | 1 | SEC ↗ |
| 13 | State Street Global Advisors ✦ (被动) | 5.43M | — | $189.71M | 0.0% | n/c | 1 | SEC ↗ |
| 14 | T. Rowe Price ✦ | 3.83M | -9.1% | $133.79M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 15 | T. Rowe Price ✦ | 3.83M | -9.1% | $133.79M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 16 | Tweedy, Browne ✦ | 3.25M | -6.0% | $113.58M | 7.7% | ▼ Trim | 3 | SEC ↗ |
| 17 | Geode Capital Management ✦ (被动) | 2.69M | +0.7% | $93.98M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 18 | Geode Capital Management ✦ (被动) | 2.69M | +0.7% | $93.98M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 19 | Citadel Advisors ✦ | 2.17M | +439.9% | $75.72M | 0.1% | ▲ Add | 3 | SEC ↗ |
| 20 | Citadel Advisors ✦ | 2.17M | +439.9% | $75.72M | 0.1% | ▲ Add | 3 | SEC ↗ |
| 21 | Norges Bank ✦ (被动) | 1.71M | -15.4% | $59.95M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 22 | ARK Investment Management ✦ | 1.03M | -25.9% | $35.84M | 0.3% | ▼ Trim | 3 | SEC ↗ |
| 23 | Two Sigma Investments ✦ | 921.44K | +0.3% | $32.21M | 0.1% | ▲ Add | 3 | SEC ↗ |
| 24 | Marshall Wace ✦ | 812.31K | -57.7% | $28.40M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 25 | Marshall Wace ✦ | 812.31K | -57.7% | $28.40M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 26 | Marshall Wace ✦ | 812.31K | -57.7% | $28.40M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 27 | Millennium Management ✦ | 774.22K | +79.8% | $27.07M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 28 | Adage Capital Partners ✦ | 275.00K | -45.0% | $9.61M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 29 | Renaissance Technologies ✦ | 205.51K | +7.9% | $7.18M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 30 | D. E. Shaw & Co. ✦ | 23.12K | -84.1% | $808,380 | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 31 | D. E. Shaw & Co. ✦ | 23.12K | -84.1% | $808,380 | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 32 | Gotham Asset Management ✦ | 6.26K | 0.0% | $218,850 | 0.0% | ▼ Trim | 3 | SEC ↗ |
"持仓权重"= 该持仓占该管理人已申报13F股权价值的比例——即信念度衡量指标。✦ = 精选管理人。
新增买入方
| 本季度无新增被追踪买入方。 |
已清仓
| Baillie Gifford | $1.59M | 曾为 0.0% |
全市场背景: 涵盖所有13F申报机构（SEC结构化数据， Q1 2026): 490 持有人, 170.17M 股份, $11.94B 已申报. 这是与上方被追踪全域数据不同的较早期间，两者从不混用。
常见共同持仓
该证券的被追踪持有人最常同时持有的其他证券——基于共同持有计数，而非基本面关联。
数据来源: 持股数据来源于已解析的13F普通股持仓（被追踪范围，变动对比集）；内部人行为来自Form 3/4/5；重大持股来自Schedule 13D/13G；所有文件均链接至SEC EDGAR原始申报。
报告期: Q4 2024 ·
方法论 ·
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