Security record · archived quarter
DFTX
Definium Therapeutics, Inc. · Healthcare · Biotechnology
105Tracked holders
+21Δ holders
65.34MShares held
$3.02BReported value
+25New positions
−4Exits
Momentum inputs (comparable managers):
holder breadth +25.0% ·
share flow +30.0% ·
net new positions +20.0%
— formula
Broad accumulation — rising shares across more holders
All ownership figures: tracked 13F managers only, common-stock positions, reporting period Q2 2026
Ownership over time
| Quarter | Holders | Δ | Shares | Reported value | New | Exits |
|---|---|---|---|---|---|---|
| Q2 2026 | 105 | +21 | 65.34M | $3.02B | +25 | −4 |
| Q1 2026 | 86 | +82 | 40.74M | $769.71M | +82 | — |
| Q4 2025 | 3 | +2 | 3.29M | $44.05M | +2 | — |
Who holds it · Q2 2026
| # | Manager | Shares | Δ shares | Value | Their weight | Held | ||
|---|---|---|---|---|---|---|---|---|
| 1 | BlackRock ✦ (passive) | 11.23M | +32.5% | $528.39M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 2 | BlackRock ✦ (passive) | 11.23M | +32.5% | $528.39M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 3 | BlackRock ✦ (passive) | 11.23M | +32.5% | $528.39M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 4 | BlackRock ✦ (passive) | 11.23M | +32.5% | $528.39M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 5 | BlackRock ✦ (passive) | 11.23M | +32.5% | $528.39M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 6 | BlackRock ✦ (passive) | 11.23M | +32.5% | $528.39M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 7 | BlackRock ✦ (passive) | 11.23M | +32.5% | $528.39M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 8 | BlackRock ✦ (passive) | 11.23M | +32.5% | $528.39M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 9 | BlackRock ✦ (passive) | 11.23M | +32.5% | $528.39M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 10 | BlackRock ✦ (passive) | 11.23M | +32.5% | $528.39M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 11 | BlackRock ✦ (passive) | 11.23M | +32.5% | $528.39M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 12 | BlackRock ✦ (passive) | 11.23M | +32.5% | $528.39M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 13 | BlackRock ✦ (passive) | 11.23M | +32.5% | $528.39M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 14 | BlackRock ✦ (passive) | 11.23M | +32.5% | $528.39M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 15 | Capital World Investors ✦ | 5.37M | New | $252.50M | 0.0% | New | 1 | SEC ↗ |
| 16 | Fidelity (FMR) ✦ | 4.75M | +162.7% | $223.58M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 17 | Fidelity (FMR) ✦ | 4.75M | +162.7% | $223.58M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 18 | Fidelity (FMR) ✦ | 4.75M | +162.7% | $223.58M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 19 | Fidelity (FMR) ✦ | 4.75M | +162.7% | $223.58M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 20 | Fidelity (FMR) ✦ | 4.75M | +162.7% | $223.58M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 21 | T. Rowe Price ✦ | 4.65M | +6545.7% | $218.83M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 22 | T. Rowe Price ✦ | 4.65M | +6545.7% | $218.83M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 23 | Geode Capital Management ✦ (passive) | 3.64M | +46.1% | $171.48M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 24 | Geode Capital Management ✦ (passive) | 3.64M | +46.1% | $171.48M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 25 | State Street Global Advisors ✦ (passive) | 3.07M | +24.0% | $144.20M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 26 | Capital International Investors | 2.96M | New | $139.40M | 0.0% | New | 1 | SEC ↗ |
| 27 | Wellington Management ✦ | 2.95M | +126.1% | $138.76M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 28 | Wellington Management ✦ | 2.95M | +126.1% | $138.76M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 29 | Wellington Management ✦ | 2.95M | +126.1% | $138.76M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 30 | Wellington Management ✦ | 2.95M | +126.1% | $138.76M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 31 | Wellington Management ✦ | 2.95M | +126.1% | $138.76M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 32 | Wellington Management ✦ | 2.95M | +126.1% | $138.76M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 33 | Wellington Management ✦ | 2.95M | +126.1% | $138.76M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 34 | Wellington Management ✦ | 2.95M | +126.1% | $138.76M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 35 | Goldman Sachs Group ✦ | 1.80M | +7.5% | $84.71M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 36 | Goldman Sachs Group ✦ | 1.80M | +7.5% | $84.71M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 37 | Goldman Sachs Group ✦ | 1.80M | +7.5% | $84.71M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 38 | Goldman Sachs Group ✦ | 1.80M | +7.5% | $84.71M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 39 | Citadel Advisors ✦ | 1.69M | +26.6% | $79.43M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 40 | Citadel Advisors ✦ | 1.69M | +26.6% | $79.43M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 41 | Vanguard Capital Management Llc | 1.49M | +35.5% | $69.92M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 42 | Marshall Wace ✦ | 1.30M | +8.2% | $61.10M | 0.1% | ▲ Add | 3 | SEC ↗ |
| 43 | Marshall Wace ✦ | 1.30M | +8.2% | $61.10M | 0.1% | ▲ Add | 3 | SEC ↗ |
| 44 | Marshall Wace ✦ | 1.30M | +8.2% | $61.10M | 0.1% | ▲ Add | 3 | SEC ↗ |
| 45 | Northern Trust Corp | 1.17M | +46.3% | $55.00M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 46 | Northern Trust Corp | 1.17M | +46.3% | $55.00M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 47 | Northern Trust Corp | 1.17M | +46.3% | $55.00M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 48 | Northern Trust Corp | 1.17M | +46.3% | $55.00M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 49 | Northern Trust Corp | 1.17M | +46.3% | $55.00M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 50 | Northern Trust Corp | 1.17M | +46.3% | $55.00M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 51 | Ameriprise Financial Inc | 1.15M | +18.8% | $54.02M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 52 | Ameriprise Financial Inc | 1.15M | +18.8% | $54.02M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 53 | Ameriprise Financial Inc | 1.15M | +18.8% | $54.02M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 54 | Ameriprise Financial Inc | 1.15M | +18.8% | $54.02M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 55 | Nuveen, LLC | 1.11M | +58.3% | $51.99M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 56 | Nuveen, LLC | 1.11M | +58.3% | $51.99M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 57 | Nuveen, LLC | 1.11M | +58.3% | $51.99M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 58 | Charles Schwab Investment… | 1.08M | +34.0% | $50.97M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 59 | Adage Capital Partners ✦ | 1.00M | -13.0% | $47.04M | 0.1% | ▼ Trim | 2 | SEC ↗ |
| 60 | Two Sigma Investments ✦ | 921.82K | -23.3% | $43.36M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 61 | Balyasny Asset Management L.P. | 897.66K | -29.6% | $42.23M | 0.1% | ▼ Trim | 2 | SEC ↗ |
| 62 | Balyasny Asset Management L.P. | 897.66K | -29.6% | $42.23M | 0.1% | ▼ Trim | 2 | SEC ↗ |
| 63 | Holocene Advisors, LP | 796.57K | -27.1% | $37.47M | 0.1% | ▼ Trim | 2 | SEC ↗ |
| 64 | Bank of New York Mellon Corp | 777.27K | +3.2% | $36.56M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 65 | Bank of New York Mellon Corp | 777.27K | +3.2% | $36.56M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 66 | Bank of New York Mellon Corp | 777.27K | +3.2% | $36.56M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 67 | Bank of New York Mellon Corp | 777.27K | +3.2% | $36.56M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 68 | Bank of New York Mellon Corp | 777.27K | +3.2% | $36.56M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 69 | Bank of New York Mellon Corp | 777.27K | +3.2% | $36.56M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 70 | Bank of New York Mellon Corp | 777.27K | +3.2% | $36.56M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 71 | Bank of New York Mellon Corp | 777.27K | +3.2% | $36.56M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 72 | Bank of New York Mellon Corp | 777.27K | +3.2% | $36.56M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 73 | Bank of New York Mellon Corp | 777.27K | +3.2% | $36.56M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 74 | Alliancebernstein L.P. | 1.80M | +1866.4% | $34.08M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 75 | Neuberger Berman Group LLC | 687.54K | +415.5% | $32.34M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 76 | Neuberger Berman Group LLC | 687.54K | +415.5% | $32.34M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 77 | Qube Research & Technologies Ltd | 682.90K | +60.3% | $32.12M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 78 | Bamco Inc /Ny/ | 520.11K | New | $24.47M | 0.0% | New | 1 | SEC ↗ |
| 79 | UBS Group AG | 499.47K | +1.1% | $23.49M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 80 | UBS Group AG | 499.47K | +1.1% | $23.49M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 81 | UBS Group AG | 499.47K | +1.1% | $23.49M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 82 | Franklin Resources Inc | 486.22K | New | $22.87M | 0.0% | New | 1 | SEC ↗ |
| 83 | Point72 Asset Management ✦ | 483.98K | +175.8% | $22.77M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 84 | Ensign Peak Advisors, Inc | 466.11K | -14.8% | $21.93M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 85 | Morgan Stanley ✦ | 454.91K | +3.7% | $21.40M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 86 | Morgan Stanley ✦ | 454.91K | +3.7% | $21.40M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 87 | Morgan Stanley ✦ | 454.91K | +3.7% | $21.40M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 88 | Morgan Stanley ✦ | 454.91K | +3.7% | $21.40M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 89 | Morgan Stanley ✦ | 454.91K | +3.7% | $21.40M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 90 | Morgan Stanley ✦ | 454.91K | +3.7% | $21.40M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 91 | Morgan Stanley ✦ | 454.91K | +3.7% | $21.40M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 92 | Morgan Stanley ✦ | 454.91K | +3.7% | $21.40M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 93 | Assetmark, Inc | 396.54K | New | $18.65M | 0.0% | New | 1 | SEC ↗ |
| 94 | Duquesne Family Office ✦ | 356.60K | New | $16.77M | 0.4% | New | 1 | SEC ↗ |
| 95 | D. E. Shaw & Co. ✦ | 315.41K | +16.1% | $14.84M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 96 | D. E. Shaw & Co. ✦ | 315.41K | +16.1% | $14.84M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 97 | Millennium Management ✦ | 266.08K | -68.6% | $12.52M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 98 | JPMorgan Chase ✦ | 265.95K | +0.5% | $12.38M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 99 | JPMorgan Chase ✦ | 265.95K | +0.5% | $12.38M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 100 | JPMorgan Chase ✦ | 265.95K | +0.5% | $12.38M | 0.0% | ▲ Add | 2 | SEC ↗ |
“Their weight” = the position's share of that manager's reported 13F equity value — the conviction measure. ✦ = curated manager.
New buyers
| Capital World Investors | $252.50M | 0.0% |
| Capital International… | $139.40M | 0.0% |
| Bamco Inc /Ny/ | $24.47M | 0.0% |
| Franklin Resources Inc | $22.87M | 0.0% |
| Assetmark, Inc | $18.65M | 0.0% |
| Duquesne Family Office | $16.77M | 0.4% |
Exited
| Jane Street Group, Llc | $4.92M | was 0.0% |
| Squarepoint Ops LLC | $2.37M | was 0.0% |
| Hrt Financial Lp | $1.68M | was 0.0% |
| Federated Hermes, Inc. | $3,912 | was 0.0% |
Full-market context: across ALL 13F filers (SEC structured data, Q1 2026): 244 holders, 74.15M shares, $1.40B reported. This is a different, older period than the tracked-universe figures above and the two are never mixed.
Frequently co-owned
What else this security's tracked holders most often hold — shared-ownership counts, not fundamental relationships.
Aug 14
SC 13G/A — DRIEHAUS CAPITAL MANAGEMENT LLC
Aug 14
SC 13G/A — Commodore Capital LP
Provenance: Ownership from parsed 13F common-stock positions (tracked universe, comparable sets for changes); insider rows from Forms 3/4/5; stakes from Schedules 13D/13G; every filing links to its original on SEC EDGAR.
Reporting period: Q2 2026 ·
Methodology ·
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