Security record
DFTX
Definium Therapeutics, Inc. · Healthcare · Biotechnology
106Tracked holders
+22Δ holders
65.35MShares held
$3.02BReported value
+26New positions
−4Exits
Momentum inputs (comparable managers):
holder breadth +26.2% ·
share flow +30.0% ·
net new positions +20.0%
— formula
Broad accumulation — rising shares across more holders
All ownership figures: tracked 13F managers only, common-stock positions, reporting period Q2 2026
Ownership over time
Who holds it · Q2 2026
| # | Manager | Shares | Δ shares | Value | Their weight | Held | ||
|---|---|---|---|---|---|---|---|---|
| 1 | BlackRock ✦ (passive) | 11.23M | +32.5% | $528.39M | 0.0% | ▲ Add | 2 | SEC ↗ ×14 |
| 2 | Capital World Investors ✦ | 5.37M | New | $252.50M | 0.0% | New | 1 | SEC ↗ |
| 3 | Fidelity (FMR) ✦ | 4.75M | +162.7% | $223.58M | 0.0% | ▲ Add | 2 | SEC ↗ ×5 |
| 4 | T. Rowe Price ✦ | 4.65M | +6545.7% | $218.83M | 0.0% | ▲ Add | 3 | SEC ↗ ×2 |
| 5 | Geode Capital Management ✦ (passive) | 3.64M | +46.1% | $171.48M | 0.0% | ▲ Add | 2 | SEC ↗ ×2 |
| 6 | State Street Global Advisors ✦ (passive) | 3.07M | +24.0% | $144.20M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 7 | Capital International Investors | 2.96M | New | $139.40M | 0.0% | New | 1 | SEC ↗ |
| 8 | Wellington Management ✦ | 2.95M | +126.1% | $138.76M | 0.0% | ▲ Add | 2 | SEC ↗ ×8 |
| 9 | Goldman Sachs Group ✦ | 1.80M | +7.5% | $84.71M | 0.0% | ▲ Add | 2 | SEC ↗ ×4 |
| 10 | Citadel Advisors ✦ | 1.69M | +26.6% | $79.43M | 0.0% | ▲ Add | 2 | SEC ↗ ×2 |
| 11 | Vanguard Capital Management Llc | 1.49M | +35.5% | $69.92M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 12 | Marshall Wace ✦ | 1.30M | +8.2% | $61.10M | 0.1% | ▲ Add | 3 | SEC ↗ ×3 |
| 13 | Northern Trust Corp | 1.17M | +46.3% | $55.00M | 0.0% | ▲ Add | 2 | SEC ↗ ×6 |
| 14 | Ameriprise Financial Inc | 1.15M | +18.8% | $54.02M | 0.0% | ▲ Add | 2 | SEC ↗ ×4 |
| 15 | Nuveen, LLC | 1.11M | +58.3% | $51.99M | 0.0% | ▲ Add | 2 | SEC ↗ ×3 |
| 16 | Charles Schwab Investment… | 1.08M | +34.0% | $50.97M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 17 | Adage Capital Partners ✦ | 1.00M | -13.0% | $47.04M | 0.1% | ▼ Trim | 2 | SEC ↗ |
| 18 | Two Sigma Investments ✦ | 921.82K | -23.3% | $43.36M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 19 | Balyasny Asset Management L.P. | 897.66K | -29.6% | $42.23M | 0.1% | ▼ Trim | 2 | SEC ↗ ×2 |
| 20 | Holocene Advisors, LP | 796.57K | -27.1% | $37.47M | 0.1% | ▼ Trim | 2 | SEC ↗ |
| 21 | Bank of New York Mellon Corp | 777.27K | +3.2% | $36.56M | 0.0% | ▲ Add | 2 | SEC ↗ ×10 |
| 22 | Alliancebernstein L.P. | 1.80M | +1866.4% | $34.08M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 23 | Neuberger Berman Group LLC | 687.54K | +415.5% | $32.34M | 0.0% | ▲ Add | 2 | SEC ↗ ×2 |
| 24 | Qube Research & Technologies Ltd | 682.90K | +60.3% | $32.12M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 25 | Bamco Inc /Ny/ | 520.11K | New | $24.47M | 0.0% | New | 1 | SEC ↗ |
| 26 | UBS Group AG | 499.47K | +1.1% | $23.49M | 0.0% | ▲ Add | 2 | SEC ↗ ×3 |
| 27 | Franklin Resources Inc | 486.22K | New | $22.87M | 0.0% | New | 1 | SEC ↗ |
| 28 | Point72 Asset Management ✦ | 483.98K | +175.8% | $22.77M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 29 | Ensign Peak Advisors, Inc | 466.11K | -14.8% | $21.93M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 30 | Morgan Stanley ✦ | 454.91K | +3.7% | $21.40M | 0.0% | ▲ Add | 2 | SEC ↗ ×8 |
| 31 | Assetmark, Inc | 396.54K | New | $18.65M | 0.0% | New | 1 | SEC ↗ |
| 32 | Duquesne Family Office ✦ | 356.60K | New | $16.77M | 0.4% | New | 1 | SEC ↗ |
| 33 | D. E. Shaw & Co. ✦ | 315.41K | +16.1% | $14.84M | 0.0% | ▲ Add | 2 | SEC ↗ ×2 |
| 34 | Millennium Management ✦ | 266.08K | -68.6% | $12.52M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 35 | JPMorgan Chase ✦ | 265.95K | +0.5% | $12.38M | 0.0% | ▲ Add | 2 | SEC ↗ ×6 |
| 36 | Swiss National Bank | 221.20K | +39.6% | $10.41M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 37 | UBS AM, a distinct business unit of… | 211.18K | +8651.9% | $9.93M | 0.0% | ▲ Add | 2 | SEC ↗ ×8 |
| 38 | Td Asset Management Inc | 209.46K | New | $9.85M | 0.0% | New | 1 | SEC ↗ |
| 39 | Aberdeen Group plc | 175.00K | New | $8.23M | 0.0% | New | 1 | SEC ↗ |
| 40 | Bank Of America Corp /De/ | 164.57K | +3.9% | $7.74M | 0.0% | ▲ Add | 2 | SEC ↗ ×3 |
| 41 | Rhumbline Advisers | 158.10K | +31.8% | $7.44M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 42 | Russell Investments Group, Ltd. | 153.48K | +28.5% | $7.22M | 0.0% | ▲ Add | 2 | SEC ↗ ×5 |
| 43 | LMR Partners LLP | 150.20K | New | $7.07M | 0.1% | New | 1 | SEC ↗ ×2 |
| 44 | Manufacturers Life Insurance… | 146.37K | +454.3% | $6.89M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 45 | Deutsche Bank Ag\ | 142.95K | -65.3% | $6.72M | 0.0% | ▼ Trim | 2 | SEC ↗ ×2 |
| 46 | AQR Capital Management ✦ | 134.15K | +135.0% | $6.31M | 0.0% | ▲ Add | 2 | SEC ↗ ×6 |
| 47 | Wells Fargo & Company/Mn | 122.03K | +205.3% | $5.74M | 0.0% | ▲ Add | 2 | SEC ↗ ×3 |
| 48 | Hsbc Holdings Plc | 117.48K | New | $5.53M | 0.0% | New | 1 | SEC ↗ ×2 |
| 49 | Royal Bank Of Canada | 100.06K | +3.0% | $4.71M | 0.0% | ▲ Add | 2 | SEC ↗ ×5 |
| 50 | Bnp Paribas Financial Markets | 96.51K | +313.2% | $4.54M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 51 | Voya Investment Management Llc | 95.17K | +480.9% | $4.48M | 0.0% | ▲ Add | 2 | SEC ↗ ×2 |
| 52 | Invesco Ltd. | 91.34K | +3.6% | $4.30M | 0.0% | ▲ Add | 2 | SEC ↗ ×5 |
| 53 | LPL Financial LLC | 86.14K | +10.1% | $4.05M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 54 | Citigroup Inc | 79.55K | +200.3% | $3.74M | 0.0% | ▲ Add | 2 | SEC ↗ ×2 |
| 55 | Legal & General Group Plc | 74.00K | +23.8% | $3.48M | 0.0% | ▲ Add | 2 | SEC ↗ ×3 |
| 56 | Quantinno Capital Management LP | 70.68K | +76.9% | $3.32M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 57 | Rockefeller Capital Management L.P. | 70.11K | +27.0% | $3.30M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 58 | Group One Trading Llc | 63.94K | -27.2% | $3.01M | 0.1% | ▼ Trim | 2 | SEC ↗ |
| 59 | MIRAE ASSET GLOBAL ETFS HOLDINGS… | 59.94K | +29.8% | $2.82M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 60 | Cerity Partners LLC | 53.88K | New | $2.53M | 0.0% | New | 1 | SEC ↗ ×3 |
| 61 | Blair William & Co/Il | 53.59K | -0.2% | $2.52M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 62 | State Of Wisconsin Investment Board | 52.55K | +4.2% | $2.47M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 63 | Barclays Plc | 50.30K | +26.7% | $2.37M | 0.0% | ▲ Add | 2 | SEC ↗ ×2 |
| 64 | Simplex Trading, Llc | 47.65K | +15.8% | $2.24M | 0.1% | ▲ Add | 2 | SEC ↗ |
| 65 | New York State Common Retirement… | 45.80K | +54.7% | $2.15M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 66 | Jennison Associates Llc | 45.38K | +13.6% | $2.13M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 67 | Susquehanna International Group, Llp | 40.95K | -49.7% | $1.93M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 68 | TD Waterhouse Canada Inc. | 36.69K | +1936.3% | $1.59M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 69 | Zurcher Kantonalbank (Zurich… | 32.39K | +55.2% | $1.52M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 70 | Sei Investments Co | 28.58K | +1.6% | $1.34M | 0.0% | ▲ Add | 2 | SEC ↗ ×2 |
| 71 | Mariner, LLC | 27.21K | -21.9% | $1.28M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 72 | Corient Private Wealth LP | 23.61K | New | $1.11M | 0.0% | New | 1 | SEC ↗ |
| 73 | Raymond James Financial Inc | 22.40K | -5.5% | $1.05M | 0.0% | ▼ Trim | 2 | SEC ↗ ×2 |
| 74 | HighTower Advisors, LLC | 22.31K | +20.2% | $1.05M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 75 | ProShare Advisors LLC | 20.61K | +10.1% | $969,730 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 76 | Walleye Trading LLC | 18.45K | +240.8% | $867,888 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 77 | Envestnet Asset Management Inc | 16.63K | New | $782,087 | 0.0% | New | 1 | SEC ↗ |
| 78 | Prudential Financial Inc | 15.50K | New | $729,120 | 0.0% | New | 1 | SEC ↗ |
| 79 | Pictet Asset Management Holding SA | 14.08K | +5.9% | $662,182 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 80 | Amundi | 14.07K | -0.5% | $661,759 | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 81 | Cetera Investment Advisers | 14.03K | -55.9% | $659,924 | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 82 | Allianz Asset Management GmbH | 13.80K | New | $649,152 | 0.0% | New | 1 | SEC ↗ |
| 83 | Stifel Financial Corp | 12.22K | -3.2% | $575,063 | 0.0% | ▼ Trim | 2 | SEC ↗ ×3 |
| 84 | Captrust Financial Advisors | 12.15K | New | $571,442 | 0.0% | New | 1 | SEC ↗ |
| 85 | Osaic Holdings, Inc. | 11.95K | +13.2% | $562,214 | 0.0% | ▲ Add | 2 | SEC ↗ ×2 |
| 86 | Mercer Global Advisors Inc /Adv | 10.28K | New | $483,477 | 0.0% | New | 1 | SEC ↗ |
| 87 | Bank Of Montreal /Can/ | 10.03K | -17.4% | $471,812 | 0.0% | ▼ Trim | 2 | SEC ↗ ×2 |
| 88 | Principal Financial Group Inc | 9.95K | New | $468,142 | 0.0% | New | 1 | SEC ↗ |
| 89 | Cibc World Market Inc. | 9.83K | -2.2% | $462,262 | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 90 | First Trust Advisors Lp | 9.53K | New | $448,150 | 0.0% | New | 1 | SEC ↗ |
| 91 | Commonwealth Equity Services, Llc | 9.45K | -7.8% | $444,532 | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 92 | Pnc Financial Services Group, Inc. | 8.57K | +12.4% | $403,086 | 0.0% | ▲ Add | 2 | SEC ↗ ×3 |
| 93 | Connor, Clark & Lunn Investment… | 8.29K | New | $390,197 | 0.0% | New | 1 | SEC ↗ |
| 94 | Wealth Enhancement Advisory… | 7.95K | New | $374,301 | 0.0% | New | 1 | SEC ↗ |
| 95 | CIBC Bancorp USA Inc. | 7.71K | New | $362,725 | 0.0% | New | 1 | SEC ↗ ×3 |
| 96 | Creative Planning | 6.91K | New | $324,858 | 0.0% | New | 1 | SEC ↗ |
| 97 | State Board Of Administration Of… | 5.01K | New | $235,482 | 0.0% | New | 1 | SEC ↗ |
| 98 | Mirae Asset Global Investments Co.… | 4.88K | -6.2% | $229,461 | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 99 | Gotham Asset Management ✦ | 4.41K | New | $207,540 | 0.0% | New | 1 | SEC ↗ |
| 100 | Fifth Third Bancorp | 3.30K | 0.0% | $155,232 | 0.0% | Held | 2 | SEC ↗ |
“Their weight” = the position's share of that manager's reported 13F equity value — the conviction measure. ✦ = curated manager.
New buyers
| Capital World Investors | $252.50M | 0.0% |
| Capital International… | $139.40M | 0.0% |
| Bamco Inc /Ny/ | $24.47M | 0.0% |
| Franklin Resources Inc | $22.87M | 0.0% |
| Assetmark, Inc | $18.65M | 0.0% |
| Duquesne Family Office | $16.77M | 0.4% |
| Td Asset Management Inc | $9.85M | 0.0% |
| Aberdeen Group plc | $8.23M | 0.0% |
| LMR Partners LLP | $7.07M | 0.1% |
| Hsbc Holdings Plc | $5.53M | 0.0% |
| Cerity Partners LLC | $2.53M | 0.0% |
| Corient Private Wealth LP | $1.11M | 0.0% |
Exited
| Jane Street Group, Llc | $4.92M | was 0.0% |
| Squarepoint Ops LLC | $2.37M | was 0.0% |
| Hrt Financial Lp | $1.68M | was 0.0% |
| Federated Hermes, Inc. | $3,912 | was 0.0% |
Full-market context: across ALL 13F filers (SEC structured data, Q1 2026): 244 holders, 74.15M shares, $1.40B reported. This is a different, older period than the tracked-universe figures above and the two are never mixed.
Frequently co-owned
What else this security's tracked holders most often hold — shared-ownership counts, not fundamental relationships.
Open-market purchases (P)
No open-market insider purchases in our coverage window.
Open-market sales (S)
Sep 25
Sullivan Mark
Officer · 14.05K sh · $513,845
Sep 25
Wiley Matthew T.
Officer · 3.10K sh · $113,257
Sep 25
Roberts Brandi
Officer · 3.38K sh · $123,497
Sep 25
Barrow Robert
Officer, Director · 31.55K sh · $1.15M
Sep 25
Karlin Daniel
Officer, Director · 10.85K sh · $396,894
Sep 03
Barrow Robert
Officer, Director · 19.02K sh · $721,733
Awards, exercises and tax withholding are never counted as buys or sales here. Methodology
Aug 14
SC 13G/A — DRIEHAUS CAPITAL MANAGEMENT LLC
Aug 14
SC 13G/A — Commodore Capital LP
Provenance: Ownership from parsed 13F common-stock positions (tracked universe, comparable sets for changes); insider rows from Forms 3/4/5; stakes from Schedules 13D/13G; every filing links to its original on SEC EDGAR.
Reporting period: Q2 2026 ·
Methodology ·
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