Security record · archived quarter
DFTX
Definium Therapeutics, Inc. · Healthcare · Biotechnology
86Tracked holders
+82Δ holders
40.74MShares held
$769.71MReported value
+82New positions
−0Exits
Momentum inputs (comparable managers):
holder breadth +30.0% ·
share flow +30.0% ·
net new positions +20.0%
· formula
Broad accumulation: rising shares across more holders
All ownership figures: tracked 13F managers only, common-stock positions, reporting period Q1 2026
Ownership over time
Who holds it · Q1 2026
| # | Manager | Shares | Δ shares | Value | Their weight | Held | ||
|---|---|---|---|---|---|---|---|---|
| 1 | BlackRock ✦ (passive) | 8.48M | New | $160.28M | 0.0% | New | 1 | SEC ↗ ×12 |
| 2 | Janus Henderson Group Plc | 3.56M | New | $67.23M | 0.0% | New | 1 | SEC ↗ ×2 |
| 3 | Geode Capital Management ✦ (passive) | 2.50M | New | $47.17M | 0.0% | New | 1 | SEC ↗ ×2 |
| 4 | State Street Global Advisors ✦ (passive) | 2.47M | New | $46.72M | 0.0% | New | 1 | SEC ↗ |
| 5 | Fidelity (FMR) ✦ | 1.81M | New | $34.20M | 0.0% | New | 1 | SEC ↗ ×3 |
| 6 | Goldman Sachs Group ✦ | 1.68M | New | $31.67M | 0.0% | New | 1 | SEC ↗ ×2 |
| 7 | Citadel Advisors ✦ | 1.33M | New | $25.20M | 0.0% | New | 1 | SEC ↗ ×2 |
| 8 | Wellington Management ✦ | 1.30M | New | $24.66M | 0.0% | New | 1 | SEC ↗ ×7 |
| 9 | Balyasny Asset Management L.P. | 1.27M | New | $24.08M | 0.0% | New | 1 | SEC ↗ |
| 10 | Two Sigma Investments ✦ | 1.20M | New | $22.71M | 0.0% | New | 1 | SEC ↗ |
| 11 | Marshall Wace ✦ | 1.20M | -59.6% | $22.70M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 12 | Adage Capital Partners ✦ | 1.15M | New | $21.73M | 0.0% | New | 1 | SEC ↗ |
| 13 | Vanguard Capital Management Llc | 1.10M | n/a | $20.73M | 0.0% | n/c | 1 | SEC ↗ |
| 14 | Holocene Advisors, LP | 1.09M | New | $20.64M | 0.1% | New | 1 | SEC ↗ |
| 15 | Ameriprise Financial Inc | 966.61K | New | $18.27M | 0.0% | New | 1 | SEC ↗ ×3 |
| 16 | Millennium Management ✦ | 846.90K | New | $16.01M | 0.0% | New | 1 | SEC ↗ |
| 17 | Charles Schwab Investment… | 808.72K | New | $15.28M | 0.0% | New | 1 | SEC ↗ |
| 18 | Northern Trust Corp | 798.99K | New | $15.10M | 0.0% | New | 1 | SEC ↗ ×5 |
| 19 | Bank of New York Mellon Corp | 752.92K | New | $14.23M | 0.0% | New | 1 | SEC ↗ ×9 |
| 20 | Nuveen, LLC | 698.13K | New | $13.19M | 0.0% | New | 1 | SEC ↗ ×3 |
| 21 | Ensign Peak Advisors, Inc | 546.78K | +108.7% | $10.33M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 22 | UBS Group AG | 493.98K | New | $9.34M | 0.0% | New | 1 | SEC ↗ ×3 |
| 23 | Morgan Stanley ✦ | 438.57K | New | $8.29M | 0.0% | New | 1 | SEC ↗ ×9 |
| 24 | Qube Research & Technologies Ltd | 426.06K | New | $8.05M | 0.0% | New | 1 | SEC ↗ |
| 25 | Deutsche Bank Ag\ | 411.83K | New | $7.78M | 0.0% | New | 1 | SEC ↗ ×2 |
| 26 | D. E. Shaw & Co. ✦ | 271.72K | New | $5.14M | 0.0% | New | 1 | SEC ↗ ×2 |
| 27 | Jane Street Group, Llc | 260.24K | New | $4.92M | 0.0% | New | 1 | SEC ↗ ×3 |
| 28 | JPMorgan Chase ✦ | 264.55K | New | $4.63M | 0.0% | New | 1 | SEC ↗ ×4 |
| 29 | Point72 Asset Management ✦ | 175.49K | New | $3.32M | 0.0% | New | 1 | SEC ↗ |
| 30 | Swiss National Bank | 158.40K | New | $2.99M | 0.0% | New | 1 | SEC ↗ |
| 31 | Bank Of America Corp /De/ | 158.34K | New | $2.99M | 0.0% | New | 1 | SEC ↗ |
| 32 | Neuberger Berman Group LLC | 133.37K | New | $2.52M | 0.0% | New | 1 | SEC ↗ ×2 |
| 33 | Squarepoint Ops LLC | 125.52K | New | $2.37M | 0.0% | New | 1 | SEC ↗ |
| 34 | Rhumbline Advisers | 119.97K | New | $2.27M | 0.0% | New | 1 | SEC ↗ |
| 35 | Russell Investments Group, Ltd. | 119.46K | New | $2.26M | 0.0% | New | 1 | SEC ↗ ×5 |
| 36 | Royal Bank Of Canada | 97.19K | New | $1.84M | 0.0% | New | 1 | SEC ↗ ×5 |
| 37 | Alliancebernstein L.P. | 91.70K | New | $1.73M | 0.0% | New | 1 | SEC ↗ |
| 38 | Hrt Financial Lp | 89.14K | New | $1.68M | 0.0% | New | 1 | SEC ↗ |
| 39 | Invesco Ltd. | 88.12K | New | $1.67M | 0.0% | New | 1 | SEC ↗ ×4 |
| 40 | Group One Trading Llc | 87.83K | New | $1.66M | 0.1% | New | 1 | SEC ↗ |
| 41 | Susquehanna International Group, Llp | 81.46K | New | $1.54M | 0.0% | New | 1 | SEC ↗ |
| 42 | LPL Financial LLC | 78.27K | New | $1.48M | 0.0% | New | 1 | SEC ↗ |
| 43 | T. Rowe Price ✦ | 70.00K | +34.0% | $1.32M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 44 | Legal & General Group Plc | 59.80K | New | $1.13M | 0.0% | New | 1 | SEC ↗ ×3 |
| 45 | AQR Capital Management ✦ | 57.09K | New | $1.08M | 0.0% | New | 1 | SEC ↗ ×6 |
| 46 | Rockefeller Capital Management L.P. | 55.21K | New | $1.04M | 0.0% | New | 1 | SEC ↗ |
| 47 | Blair William & Co/Il | 53.70K | New | $1.01M | 0.0% | New | 1 | SEC ↗ |
| 48 | State Of Wisconsin Investment Board | 50.42K | New | $952,938 | 0.0% | New | 1 | SEC ↗ |
| 49 | MIRAE ASSET GLOBAL ETFS HOLDINGS… | 46.19K | New | $873,048 | 0.0% | New | 1 | SEC ↗ |
| 50 | Simplex Trading, Llc | 41.16K | New | $777,848 | 0.0% | New | 1 | SEC ↗ |
| 51 | Wells Fargo & Company/Mn | 39.97K | New | $755,490 | 0.0% | New | 1 | SEC ↗ ×2 |
| 52 | Quantinno Capital Management LP | 39.96K | New | $755,206 | 0.0% | New | 1 | SEC ↗ |
| 53 | Jennison Associates Llc | 39.96K | New | $755,187 | 0.0% | New | 1 | SEC ↗ |
| 54 | Barclays Plc | 39.68K | New | $750,009 | 0.0% | New | 1 | SEC ↗ ×3 |
| 55 | Mariner, LLC | 34.85K | New | $658,643 | 0.0% | New | 1 | SEC ↗ |
| 56 | Cetera Investment Advisers | 31.82K | New | $601,474 | 0.0% | New | 1 | SEC ↗ |
| 57 | New York State Common Retirement… | 29.60K | New | $559,440 | 0.0% | New | 1 | SEC ↗ |
| 58 | Sei Investments Co | 28.12K | New | $531,425 | 0.0% | New | 1 | SEC ↗ ×2 |
| 59 | Citigroup Inc | 26.49K | New | $500,585 | 0.0% | New | 1 | SEC ↗ ×2 |
| 60 | Manufacturers Life Insurance… | 26.40K | New | $499,036 | 0.0% | New | 1 | SEC ↗ |
| 61 | Raymond James Financial Inc | 23.71K | New | $448,175 | 0.0% | New | 1 | SEC ↗ ×2 |
| 62 | Bnp Paribas Financial Markets | 23.36K | New | $441,428 | 0.0% | New | 1 | SEC ↗ |
| 63 | Zurcher Kantonalbank (Zurich… | 20.87K | New | $394,405 | 0.0% | New | 1 | SEC ↗ |
| 64 | ProShare Advisors LLC | 18.73K | New | $354,015 | 0.0% | New | 1 | SEC ↗ |
| 65 | HighTower Advisors, LLC | 18.56K | New | $350,756 | 0.0% | New | 1 | SEC ↗ |
| 66 | Voya Investment Management Llc | 16.38K | New | $309,658 | 0.0% | New | 1 | SEC ↗ |
| 67 | Amundi | 14.14K | New | $267,170 | 0.0% | New | 1 | SEC ↗ |
| 68 | Pictet Asset Management Holding SA | 13.29K | New | $251,275 | 0.0% | New | 1 | SEC ↗ |
| 69 | Stifel Financial Corp | 12.63K | New | $238,632 | 0.0% | New | 1 | SEC ↗ ×3 |
| 70 | Bank Of Montreal /Can/ | 12.14K | New | $229,371 | 0.0% | New | 1 | SEC ↗ ×2 |
| 71 | Osaic Holdings, Inc. | 10.56K | New | $199,556 | 0.0% | New | 1 | SEC ↗ ×2 |
| 72 | Commonwealth Equity Services, Llc | 10.25K | New | $193,739 | 0.0% | New | 1 | SEC ↗ |
| 73 | Cibc World Market Inc. | 10.05K | New | $189,926 | 0.0% | New | 1 | SEC ↗ |
| 74 | Pnc Financial Services Group, Inc. | 7.62K | New | $144,019 | 0.0% | New | 1 | SEC ↗ ×3 |
| 75 | Cwm, Llc | 5.60K | New | $105,840 | 0.0% | New | 1 | SEC ↗ |
| 76 | Walleye Trading LLC | 5.41K | New | $102,325 | 0.0% | New | 1 | SEC ↗ |
| 77 | Mirae Asset Global Investments Co.… | 5.20K | New | $98,280 | 0.0% | New | 1 | SEC ↗ |
| 78 | Fifth Third Bancorp | 3.30K | New | $62,370 | 0.0% | New | 1 | SEC ↗ |
| 79 | UBS AM, a distinct business unit of… | 2.41K | New | $45,606 | 0.0% | New | 1 | SEC ↗ |
| 80 | TD Waterhouse Canada Inc. | 1.80K | New | $37,068 | 0.0% | New | 1 | SEC ↗ |
| 81 | BNP Paribas Asset Management… | 1.81K | New | $34,247 | 0.0% | New | 1 | SEC ↗ |
| 82 | National Bank Of Canada /Fi/ | 1.71K | New | $32,264 | 0.0% | New | 1 | SEC ↗ |
| 83 | Federated Hermes, Inc. | 207 | New | $3,912 | 0.0% | New | 1 | SEC ↗ |
| 84 | Jones Financial Companies Lllp | 180 | New | $3,218 | 0.0% | New | 1 | SEC ↗ |
| 85 | Northwestern Mutual Wealth… | 155 | New | $2,930 | 0.0% | New | 1 | SEC ↗ |
| 86 | Optiver Holding B.V. | 49 | New | $926 | 0.0% | New | 1 | SEC ↗ |
“Their weight” = the position's share of that manager's reported 13F equity value: the conviction measure. ✦ = curated manager.
New buyers
| BlackRock | $160.28M | 0.0% |
| Janus Henderson Group Plc | $67.23M | 0.0% |
| Geode Capital Management | $47.17M | 0.0% |
| State Street Global Advisors | $46.72M | 0.0% |
| Fidelity (FMR) | $34.20M | 0.0% |
| Goldman Sachs Group | $31.67M | 0.0% |
| Citadel Advisors | $25.20M | 0.0% |
| Wellington Management | $24.66M | 0.0% |
| Balyasny Asset Management L.P. | $24.08M | 0.0% |
| Two Sigma Investments | $22.71M | 0.0% |
| Adage Capital Partners | $21.73M | 0.0% |
| Holocene Advisors, LP | $20.64M | 0.1% |
Exited
| No tracked exits this quarter. |
Full-market context: across ALL 13F filers (SEC structured data, Q1 2026): 244 holders, 74.15M shares, $1.40B reported. This is a different, older period than the tracked-universe figures above and the two are never mixed.
Frequently co-owned
What else this security's tracked holders most often hold: shared-ownership counts, not fundamental relationships.
Open-market purchases (P)
No open-market insider purchases in our coverage window.
Open-market sales (S)
Sep 25
Sullivan Mark
Officer · 14.05K sh · $513,845
Sep 25
Wiley Matthew T.
Officer · 3.10K sh · $113,257
Sep 25
Roberts Brandi
Officer · 3.38K sh · $123,497
Sep 25
Barrow Robert
Officer, Director · 31.55K sh · $1.15M
Sep 25
Karlin Daniel
Officer, Director · 10.85K sh · $396,894
Sep 03
Barrow Robert
Officer, Director · 19.02K sh · $721,733
Awards, exercises and tax withholding are never counted as buys or sales here. Methodology
Aug 14
SC 13G/A: DRIEHAUS CAPITAL MANAGEMENT LLC
Aug 14
SC 13G/A: Commodore Capital LP
Provenance: Ownership from parsed 13F common-stock positions (tracked universe, comparable sets for changes); insider rows from Forms 3/4/5; stakes from Schedules 13D/13G; every filing links to its original on SEC EDGAR.
Reporting period: Q1 2026 ·
Methodology ·
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