Security record · archived quarter
DFTX
Definium Therapeutics, Inc. · Healthcare · Biotechnology
86Tracked holders
+82Δ holders
40.74MShares held
$769.71MReported value
+82New positions
−0Exits
Momentum inputs (comparable managers):
holder breadth +30.0% ·
share flow +30.0% ·
net new positions +20.0%
— formula
Broad accumulation — rising shares across more holders
All ownership figures: tracked 13F managers only, common-stock positions, reporting period Q1 2026
Ownership over time
| Quarter | Holders | Δ | Shares | Reported value | New | Exits |
|---|---|---|---|---|---|---|
| Q2 2026 | 105 | +21 | 65.34M | $3.02B | +25 | −4 |
| Q1 2026 | 86 | +82 | 40.74M | $769.71M | +82 | — |
| Q4 2025 | 3 | +2 | 3.29M | $44.05M | +2 | — |
Who holds it · Q1 2026
| # | Manager | Shares | Δ shares | Value | Their weight | Held | ||
|---|---|---|---|---|---|---|---|---|
| 1 | BlackRock ✦ (passive) | 8.48M | New | $160.28M | 0.0% | New | 1 | SEC ↗ |
| 2 | BlackRock ✦ (passive) | 8.48M | New | $160.28M | 0.0% | New | 1 | SEC ↗ |
| 3 | BlackRock ✦ (passive) | 8.48M | New | $160.28M | 0.0% | New | 1 | SEC ↗ |
| 4 | BlackRock ✦ (passive) | 8.48M | New | $160.28M | 0.0% | New | 1 | SEC ↗ |
| 5 | BlackRock ✦ (passive) | 8.48M | New | $160.28M | 0.0% | New | 1 | SEC ↗ |
| 6 | BlackRock ✦ (passive) | 8.48M | New | $160.28M | 0.0% | New | 1 | SEC ↗ |
| 7 | BlackRock ✦ (passive) | 8.48M | New | $160.28M | 0.0% | New | 1 | SEC ↗ |
| 8 | BlackRock ✦ (passive) | 8.48M | New | $160.28M | 0.0% | New | 1 | SEC ↗ |
| 9 | BlackRock ✦ (passive) | 8.48M | New | $160.28M | 0.0% | New | 1 | SEC ↗ |
| 10 | BlackRock ✦ (passive) | 8.48M | New | $160.28M | 0.0% | New | 1 | SEC ↗ |
| 11 | BlackRock ✦ (passive) | 8.48M | New | $160.28M | 0.0% | New | 1 | SEC ↗ |
| 12 | BlackRock ✦ (passive) | 8.48M | New | $160.28M | 0.0% | New | 1 | SEC ↗ |
| 13 | Janus Henderson Group Plc | 3.56M | New | $67.23M | 0.0% | New | 1 | SEC ↗ |
| 14 | Janus Henderson Group Plc | 3.56M | New | $67.23M | 0.0% | New | 1 | SEC ↗ |
| 15 | Geode Capital Management ✦ (passive) | 2.50M | New | $47.17M | 0.0% | New | 1 | SEC ↗ |
| 16 | Geode Capital Management ✦ (passive) | 2.50M | New | $47.17M | 0.0% | New | 1 | SEC ↗ |
| 17 | State Street Global Advisors ✦ (passive) | 2.47M | New | $46.72M | 0.0% | New | 1 | SEC ↗ |
| 18 | Fidelity (FMR) ✦ | 1.81M | New | $34.20M | 0.0% | New | 1 | SEC ↗ |
| 19 | Fidelity (FMR) ✦ | 1.81M | New | $34.20M | 0.0% | New | 1 | SEC ↗ |
| 20 | Fidelity (FMR) ✦ | 1.81M | New | $34.20M | 0.0% | New | 1 | SEC ↗ |
| 21 | Goldman Sachs Group ✦ | 1.68M | New | $31.67M | 0.0% | New | 1 | SEC ↗ |
| 22 | Goldman Sachs Group ✦ | 1.68M | New | $31.67M | 0.0% | New | 1 | SEC ↗ |
| 23 | Citadel Advisors ✦ | 1.33M | New | $25.20M | 0.0% | New | 1 | SEC ↗ |
| 24 | Citadel Advisors ✦ | 1.33M | New | $25.20M | 0.0% | New | 1 | SEC ↗ |
| 25 | Wellington Management ✦ | 1.30M | New | $24.66M | 0.0% | New | 1 | SEC ↗ |
| 26 | Wellington Management ✦ | 1.30M | New | $24.66M | 0.0% | New | 1 | SEC ↗ |
| 27 | Wellington Management ✦ | 1.30M | New | $24.66M | 0.0% | New | 1 | SEC ↗ |
| 28 | Wellington Management ✦ | 1.30M | New | $24.66M | 0.0% | New | 1 | SEC ↗ |
| 29 | Wellington Management ✦ | 1.30M | New | $24.66M | 0.0% | New | 1 | SEC ↗ |
| 30 | Wellington Management ✦ | 1.30M | New | $24.66M | 0.0% | New | 1 | SEC ↗ |
| 31 | Wellington Management ✦ | 1.30M | New | $24.66M | 0.0% | New | 1 | SEC ↗ |
| 32 | Balyasny Asset Management L.P. | 1.27M | New | $24.08M | 0.0% | New | 1 | SEC ↗ |
| 33 | Two Sigma Investments ✦ | 1.20M | New | $22.71M | 0.0% | New | 1 | SEC ↗ |
| 34 | Marshall Wace ✦ | 1.20M | -59.6% | $22.70M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 35 | Adage Capital Partners ✦ | 1.15M | New | $21.73M | 0.0% | New | 1 | SEC ↗ |
| 36 | Vanguard Capital Management Llc | 1.10M | — | $20.73M | 0.0% | n/c | 1 | SEC ↗ |
| 37 | Holocene Advisors, LP | 1.09M | New | $20.64M | 0.1% | New | 1 | SEC ↗ |
| 38 | Ameriprise Financial Inc | 966.61K | New | $18.27M | 0.0% | New | 1 | SEC ↗ |
| 39 | Ameriprise Financial Inc | 966.61K | New | $18.27M | 0.0% | New | 1 | SEC ↗ |
| 40 | Ameriprise Financial Inc | 966.61K | New | $18.27M | 0.0% | New | 1 | SEC ↗ |
| 41 | Millennium Management ✦ | 846.90K | New | $16.01M | 0.0% | New | 1 | SEC ↗ |
| 42 | Charles Schwab Investment… | 808.72K | New | $15.28M | 0.0% | New | 1 | SEC ↗ |
| 43 | Northern Trust Corp | 798.99K | New | $15.10M | 0.0% | New | 1 | SEC ↗ |
| 44 | Northern Trust Corp | 798.99K | New | $15.10M | 0.0% | New | 1 | SEC ↗ |
| 45 | Northern Trust Corp | 798.99K | New | $15.10M | 0.0% | New | 1 | SEC ↗ |
| 46 | Northern Trust Corp | 798.99K | New | $15.10M | 0.0% | New | 1 | SEC ↗ |
| 47 | Northern Trust Corp | 798.99K | New | $15.10M | 0.0% | New | 1 | SEC ↗ |
| 48 | Bank of New York Mellon Corp | 752.92K | New | $14.23M | 0.0% | New | 1 | SEC ↗ |
| 49 | Bank of New York Mellon Corp | 752.92K | New | $14.23M | 0.0% | New | 1 | SEC ↗ |
| 50 | Bank of New York Mellon Corp | 752.92K | New | $14.23M | 0.0% | New | 1 | SEC ↗ |
| 51 | Bank of New York Mellon Corp | 752.92K | New | $14.23M | 0.0% | New | 1 | SEC ↗ |
| 52 | Bank of New York Mellon Corp | 752.92K | New | $14.23M | 0.0% | New | 1 | SEC ↗ |
| 53 | Bank of New York Mellon Corp | 752.92K | New | $14.23M | 0.0% | New | 1 | SEC ↗ |
| 54 | Bank of New York Mellon Corp | 752.92K | New | $14.23M | 0.0% | New | 1 | SEC ↗ |
| 55 | Bank of New York Mellon Corp | 752.92K | New | $14.23M | 0.0% | New | 1 | SEC ↗ |
| 56 | Bank of New York Mellon Corp | 752.92K | New | $14.23M | 0.0% | New | 1 | SEC ↗ |
| 57 | Nuveen, LLC | 698.13K | New | $13.19M | 0.0% | New | 1 | SEC ↗ |
| 58 | Nuveen, LLC | 698.13K | New | $13.19M | 0.0% | New | 1 | SEC ↗ |
| 59 | Nuveen, LLC | 698.13K | New | $13.19M | 0.0% | New | 1 | SEC ↗ |
| 60 | Ensign Peak Advisors, Inc | 546.78K | +108.7% | $10.33M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 61 | UBS Group AG | 493.98K | New | $9.34M | 0.0% | New | 1 | SEC ↗ |
| 62 | UBS Group AG | 493.98K | New | $9.34M | 0.0% | New | 1 | SEC ↗ |
| 63 | UBS Group AG | 493.98K | New | $9.34M | 0.0% | New | 1 | SEC ↗ |
| 64 | Morgan Stanley ✦ | 438.57K | New | $8.29M | 0.0% | New | 1 | SEC ↗ |
| 65 | Morgan Stanley ✦ | 438.57K | New | $8.29M | 0.0% | New | 1 | SEC ↗ |
| 66 | Morgan Stanley ✦ | 438.57K | New | $8.29M | 0.0% | New | 1 | SEC ↗ |
| 67 | Morgan Stanley ✦ | 438.57K | New | $8.29M | 0.0% | New | 1 | SEC ↗ |
| 68 | Morgan Stanley ✦ | 438.57K | New | $8.29M | 0.0% | New | 1 | SEC ↗ |
| 69 | Morgan Stanley ✦ | 438.57K | New | $8.29M | 0.0% | New | 1 | SEC ↗ |
| 70 | Morgan Stanley ✦ | 438.57K | New | $8.29M | 0.0% | New | 1 | SEC ↗ |
| 71 | Morgan Stanley ✦ | 438.57K | New | $8.29M | 0.0% | New | 1 | SEC ↗ |
| 72 | Morgan Stanley ✦ | 438.57K | New | $8.29M | 0.0% | New | 1 | SEC ↗ |
| 73 | Qube Research & Technologies Ltd | 426.06K | New | $8.05M | 0.0% | New | 1 | SEC ↗ |
| 74 | Deutsche Bank Ag\ | 411.83K | New | $7.78M | 0.0% | New | 1 | SEC ↗ |
| 75 | Deutsche Bank Ag\ | 411.83K | New | $7.78M | 0.0% | New | 1 | SEC ↗ |
| 76 | D. E. Shaw & Co. ✦ | 271.72K | New | $5.14M | 0.0% | New | 1 | SEC ↗ |
| 77 | D. E. Shaw & Co. ✦ | 271.72K | New | $5.14M | 0.0% | New | 1 | SEC ↗ |
| 78 | Jane Street Group, Llc | 260.24K | New | $4.92M | 0.0% | New | 1 | SEC ↗ |
| 79 | Jane Street Group, Llc | 260.24K | New | $4.92M | 0.0% | New | 1 | SEC ↗ |
| 80 | Jane Street Group, Llc | 260.24K | New | $4.92M | 0.0% | New | 1 | SEC ↗ |
| 81 | JPMorgan Chase ✦ | 264.55K | New | $4.63M | 0.0% | New | 1 | SEC ↗ |
| 82 | JPMorgan Chase ✦ | 264.55K | New | $4.63M | 0.0% | New | 1 | SEC ↗ |
| 83 | JPMorgan Chase ✦ | 264.55K | New | $4.63M | 0.0% | New | 1 | SEC ↗ |
| 84 | JPMorgan Chase ✦ | 264.55K | New | $4.63M | 0.0% | New | 1 | SEC ↗ |
| 85 | Point72 Asset Management ✦ | 175.49K | New | $3.32M | 0.0% | New | 1 | SEC ↗ |
| 86 | Swiss National Bank | 158.40K | New | $2.99M | 0.0% | New | 1 | SEC ↗ |
| 87 | Bank Of America Corp /De/ | 158.34K | New | $2.99M | 0.0% | New | 1 | SEC ↗ |
| 88 | Neuberger Berman Group LLC | 133.37K | New | $2.52M | 0.0% | New | 1 | SEC ↗ |
| 89 | Neuberger Berman Group LLC | 133.37K | New | $2.52M | 0.0% | New | 1 | SEC ↗ |
| 90 | Squarepoint Ops LLC | 125.52K | New | $2.37M | 0.0% | New | 1 | SEC ↗ |
| 91 | Rhumbline Advisers | 119.97K | New | $2.27M | 0.0% | New | 1 | SEC ↗ |
| 92 | Russell Investments Group, Ltd. | 119.46K | New | $2.26M | 0.0% | New | 1 | SEC ↗ |
| 93 | Russell Investments Group, Ltd. | 119.46K | New | $2.26M | 0.0% | New | 1 | SEC ↗ |
| 94 | Russell Investments Group, Ltd. | 119.46K | New | $2.26M | 0.0% | New | 1 | SEC ↗ |
| 95 | Russell Investments Group, Ltd. | 119.46K | New | $2.26M | 0.0% | New | 1 | SEC ↗ |
| 96 | Russell Investments Group, Ltd. | 119.46K | New | $2.26M | 0.0% | New | 1 | SEC ↗ |
| 97 | Royal Bank Of Canada | 97.19K | New | $1.84M | 0.0% | New | 1 | SEC ↗ |
| 98 | Royal Bank Of Canada | 97.19K | New | $1.84M | 0.0% | New | 1 | SEC ↗ |
| 99 | Royal Bank Of Canada | 97.19K | New | $1.84M | 0.0% | New | 1 | SEC ↗ |
| 100 | Royal Bank Of Canada | 97.19K | New | $1.84M | 0.0% | New | 1 | SEC ↗ |
“Their weight” = the position's share of that manager's reported 13F equity value — the conviction measure. ✦ = curated manager.
New buyers
| BlackRock | $160.28M | 0.0% |
| BlackRock | $160.28M | 0.0% |
| BlackRock | $160.28M | 0.0% |
| BlackRock | $160.28M | 0.0% |
| BlackRock | $160.28M | 0.0% |
| BlackRock | $160.28M | 0.0% |
| BlackRock | $160.28M | 0.0% |
| BlackRock | $160.28M | 0.0% |
| BlackRock | $160.28M | 0.0% |
| BlackRock | $160.28M | 0.0% |
| BlackRock | $160.28M | 0.0% |
| BlackRock | $160.28M | 0.0% |
Exited
| No tracked exits this quarter. |
Full-market context: across ALL 13F filers (SEC structured data, Q1 2026): 244 holders, 74.15M shares, $1.40B reported. This is a different, older period than the tracked-universe figures above and the two are never mixed.
Frequently co-owned
What else this security's tracked holders most often hold — shared-ownership counts, not fundamental relationships.
Aug 14
SC 13G/A — DRIEHAUS CAPITAL MANAGEMENT LLC
Aug 14
SC 13G/A — Commodore Capital LP
Provenance: Ownership from parsed 13F common-stock positions (tracked universe, comparable sets for changes); insider rows from Forms 3/4/5; stakes from Schedules 13D/13G; every filing links to its original on SEC EDGAR.
Reporting period: Q1 2026 ·
Methodology ·
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