CSTL
Castle Biosciences, Inc. · Healthcare · Medical - Diagnostics & Research
Momentum inputs (comparable managers):
holder breadth +2.4% ·
share flow -1.0% ·
net new positions +2.3%
— formula
Ownership fragmentation — more holders, smaller aggregate stake
All ownership figures: tracked 13F managers only, common-stock positions, reporting period Q4 2025
| Quarter | Holders | Δ | Shares | Reported value | New | Exits |
|---|---|---|---|---|---|---|
| Q2 2026 | 76 | -1 | 16.83M | $401.45M | +6 | −6 |
| Q1 2026 | 79 | -9 | 16.13M | $395.93M | +4 | −13 |
| Q4 2025 | 87 | +2 | 17.12M | $665.58M | +2 | — |
| Q3 2025 | 16 | 0 | 9.41M | $214.29M | +1 | −1 |
| Q2 2025 | 13 | -1 | 9.39M | $191.81M | — | −1 |
| Q1 2025 | 11 | 0 | 4.13M | $82.76M | +1 | −1 |
| Q4 2024 | 11 | +2 | 4.84M | $128.97M | +4 | −2 |
| Q3 2024 | 8 | 0 | 2.64M | $75.25M | — | — |
| Q2 2024 | 8 | — | 1.95M | $42.47M | — | — |
| # | Manager | Shares | Δ shares | Value | Their weight | Held | ||
|---|---|---|---|---|---|---|---|---|
| 1 | BlackRock ✦ (passive) | 3.11M | -2.6% | $120.79M | 0.0% | ▼ Trim | 3 | SEC ↗ ×15 |
| 2 | The Vanguard Group ✦ (passive) | 2.20M | +1.3% | $85.57M | 0.0% | ▲ Add | 3 | SEC ↗ ×5 |
| 3 | Principal Financial Group Inc | 1.81M | — | $70.32M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 4 | Dimensional Fund Advisors Lp | 1.14M | — | $44.49M | 0.0% | n/c | 1 | SEC ↗ ×5 |
| 5 | State Street Global Advisors ✦ (passive) | 736.45K | +1.7% | $28.65M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 6 | Geode Capital Management ✦ (passive) | 714.91K | +2.3% | $27.81M | 0.0% | ▲ Add | 7 | SEC ↗ ×2 |
| 7 | Allianz Asset Management GmbH | 622.30K | — | $24.21M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 8 | Nuveen, LLC | 524.68K | — | $20.41M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 9 | Renaissance Technologies ✦ | 493.10K | -12.3% | $19.18M | 0.0% | ▼ Trim | 7 | SEC ↗ |
| 10 | Connor, Clark & Lunn Investment… | 388.49K | — | $15.11M | 0.0% | n/c | 1 | SEC ↗ |
| 11 | Citadel Advisors ✦ | 366.36K | +46.0% | $14.25M | 0.0% | ▲ Add | 7 | SEC ↗ ×2 |
| 12 | Millennium Management ✦ | 308.91K | -46.3% | $12.02M | 0.0% | ▼ Trim | 7 | SEC ↗ |
| 13 | Goldman Sachs Group ✦ | 287.24K | -16.8% | $11.17M | 0.0% | ▼ Trim | 2 | SEC ↗ ×2 |
| 14 | Bank Of America Corp /De/ | 263.02K | — | $10.23M | 0.0% | n/c | 1 | SEC ↗ ×5 |
| 15 | Northern Trust Corp | 262.24K | — | $10.20M | 0.0% | n/c | 1 | SEC ↗ ×6 |
| 16 | Charles Schwab Investment… | 242.53K | — | $9.43M | 0.0% | n/c | 1 | SEC ↗ |
| 17 | Qube Research & Technologies Ltd | 235.52K | — | $9.16M | 0.0% | n/c | 1 | SEC ↗ |
| 18 | New York State Common Retirement… | 233.05K | — | $9.07M | 0.0% | n/c | 1 | SEC ↗ |
| 19 | Wellington Management ✦ | 218.56K | New | $8.50M | 0.0% | New | 1 | SEC ↗ ×4 |
| 20 | Morgan Stanley ✦ | 203.58K | -24.5% | $7.92M | 0.0% | ▼ Trim | 2 | SEC ↗ ×7 |
| 21 | Jane Street Group, Llc | 168.65K | — | $6.56M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 22 | Tudor Investment Corp Et Al | 167.18K | — | $6.50M | 0.0% | n/c | 1 | SEC ↗ |
| 23 | D. E. Shaw & Co. ✦ | 159.71K | +72.5% | $6.21M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 24 | Allspring Global Investments… | 159.17K | — | $6.13M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 25 | Bnp Paribas Financial Markets | 150.01K | — | $5.84M | 0.0% | n/c | 1 | SEC ↗ |
| 26 | UBS Group AG | 141.87K | — | $5.52M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 27 | Invesco Ltd. | 135.46K | — | $5.27M | 0.0% | n/c | 1 | SEC ↗ ×4 |
| 28 | Point72 Asset Management ✦ | 119.46K | -64.5% | $4.65M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 29 | JPMorgan Chase ✦ | 90.03K | +62.1% | $3.50M | 0.0% | ▲ Add | 2 | SEC ↗ ×4 |
| 30 | Bank of New York Mellon Corp | 86.98K | — | $3.38M | 0.0% | n/c | 1 | SEC ↗ ×4 |
| 31 | Two Sigma Investments ✦ | 84.07K | +227.1% | $3.27M | 0.0% | ▲ Add | 4 | SEC ↗ |
| 32 | Franklin Resources Inc | 80.60K | — | $3.14M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 33 | American Century Companies Inc | 77.77K | — | $3.03M | 0.0% | n/c | 1 | SEC ↗ |
| 34 | Barclays Plc | 72.15K | — | $2.81M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 35 | UBS AM, a distinct business unit of… | 69.63K | — | $2.71M | 0.0% | n/c | 1 | SEC ↗ ×8 |
| 36 | AQR Capital Management ✦ | 63.88K | +25.6% | $2.48M | 0.0% | ▲ Add | 5 | SEC ↗ ×5 |
| 37 | Envestnet Asset Management Inc | 61.97K | — | $2.41M | 0.0% | n/c | 1 | SEC ↗ |
| 38 | Swiss National Bank | 57.30K | — | $2.23M | 0.0% | n/c | 1 | SEC ↗ |
| 39 | Squarepoint Ops LLC | 55.12K | — | $2.14M | 0.0% | n/c | 1 | SEC ↗ |
| 40 | Hrt Financial Lp | 47.65K | — | $1.85M | 0.0% | n/c | 1 | SEC ↗ |
| 41 | Fidelity (FMR) ✦ | 42.29K | +48.1% | $1.64M | 0.0% | ▲ Add | 3 | SEC ↗ ×2 |
| 42 | Sei Investments Co | 39.73K | — | $1.55M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 43 | Hsbc Holdings Plc | 38.97K | — | $1.52M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 44 | Rhumbline Advisers | 38.47K | — | $1.50M | 0.0% | n/c | 1 | SEC ↗ |
| 45 | Mackenzie Financial Corp | 37.32K | — | $1.46M | 0.0% | n/c | 1 | SEC ↗ |
| 46 | Osaic Holdings, Inc. | 36.40K | — | $1.42M | 0.0% | n/c | 1 | SEC ↗ |
| 47 | Ameriprise Financial Inc | 35.37K | — | $1.38M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 48 | Wells Fargo & Company/Mn | 34.21K | — | $1.33M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 49 | T. Rowe Price ✦ | 34.14K | +4.7% | $1.33M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 50 | Citigroup Inc | 32.42K | — | $1.26M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 51 | Legal & General Group Plc | 29.73K | — | $1.16M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 52 | Universal- Beteiligungs- und… | 29.36K | — | $1.14M | 0.0% | n/c | 1 | SEC ↗ |
| 53 | California State Teachers… | 27.73K | — | $1.08M | 0.0% | n/c | 1 | SEC ↗ |
| 54 | Alliancebernstein L.P. | 25.27K | — | $983,003 | 0.0% | n/c | 1 | SEC ↗ |
| 55 | Truist Financial Corp | 23.63K | — | $919,129 | 0.0% | n/c | 1 | SEC ↗ |
| 56 | Deutsche Bank Ag\ | 22.38K | — | $870,738 | 0.0% | n/c | 1 | SEC ↗ |
| 57 | Creative Planning | 16.14K | — | $627,885 | 0.0% | n/c | 1 | SEC ↗ |
| 58 | Janus Henderson Group Plc | 15.04K | — | $585,014 | 0.0% | n/c | 1 | SEC ↗ |
| 59 | MIRAE ASSET GLOBAL ETFS HOLDINGS… | 13.22K | — | $514,375 | 0.0% | n/c | 1 | SEC ↗ |
| 60 | Zurcher Kantonalbank (Zurich… | 11.81K | — | $459,409 | 0.0% | n/c | 1 | SEC ↗ |
| 61 | Man Group plc | 11.59K | — | $450,657 | 0.0% | n/c | 1 | SEC ↗ |
| 62 | LPL Financial LLC | 10.88K | — | $423,115 | 0.0% | n/c | 1 | SEC ↗ |
| 63 | Quantinno Capital Management LP | 9.33K | — | $363,015 | 0.0% | n/c | 1 | SEC ↗ |
| 64 | Cetera Investment Advisers | 8.94K | — | $347,572 | 0.0% | n/c | 1 | SEC ↗ |
| 65 | Manufacturers Life Insurance… | 8.49K | — | $330,144 | 0.0% | n/c | 1 | SEC ↗ |
| 66 | State Board Of Administration Of… | 7.15K | — | $278,291 | 0.0% | n/c | 1 | SEC ↗ |
| 67 | Arrowstreet Capital ✦ | 7.03K | New | $273,428 | 0.0% | New | 1 | SEC ↗ |
| 68 | Commonwealth Equity Services, Llc | 6.59K | — | $256,390 | 0.0% | n/c | 1 | SEC ↗ |
| 69 | ProShare Advisors LLC | 6.48K | — | $251,994 | 0.0% | n/c | 1 | SEC ↗ |
| 70 | Canada Pension Plan Investment Board | 6.30K | — | $245,070 | 0.0% | n/c | 1 | SEC ↗ |
| 71 | Pictet Asset Management Holding SA | 5.90K | — | $229,471 | 0.0% | n/c | 1 | SEC ↗ |
| 72 | Lido Advisors, LLC | 10.04K | — | $228,520 | 0.0% | n/c | 1 | SEC ↗ |
| 73 | Assetmark, Inc | 5.29K | — | $205,664 | 0.0% | n/c | 1 | SEC ↗ |
| 74 | Voya Investment Management Llc | 5.25K | — | $204,069 | 0.0% | n/c | 1 | SEC ↗ |
| 75 | Raymond James Financial Inc | 5.24K | — | $203,759 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 76 | Russell Investments Group, Ltd. | 2.49K | — | $96,783 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 77 | Cwm, Llc | 2.30K | — | $90,000 | 0.0% | n/c | 1 | SEC ↗ |
| 78 | BNP Paribas Asset Management… | 1.84K | — | $72,000 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 79 | Mirae Asset Global Investments Co.… | 1.42K | — | $55,160 | 0.0% | n/c | 1 | SEC ↗ |
| 80 | Royal Bank Of Canada | 865 | — | $33,000 | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 81 | Federated Hermes, Inc. | 660 | — | $25,674 | 0.0% | n/c | 1 | SEC ↗ |
| 82 | Pnc Financial Services Group, Inc. | 546 | — | $21,239 | 0.0% | n/c | 1 | SEC ↗ |
| 83 | Jones Financial Companies Lllp | 515 | — | $20,034 | 0.0% | n/c | 1 | SEC ↗ |
| 84 | Rockefeller Capital Management L.P. | 87 | — | $3,384 | 0.0% | n/c | 1 | SEC ↗ |
| 85 | Daiwa Securities Group Inc. | 86 | — | $3,000 | 0.0% | n/c | 1 | SEC ↗ |
| 86 | Us Bancorp \De\ | 48 | — | $1,867 | 0.0% | n/c | 1 | SEC ↗ |
| 87 | Northwestern Mutual Wealth… | 28 | — | $1,089 | 0.0% | n/c | 1 | SEC ↗ |
“Their weight” = the position's share of that manager's reported 13F equity value — the conviction measure. ✦ = curated manager.
New buyers
| Wellington Management | $8.50M | 0.0% |
| Arrowstreet Capital | $273,428 | 0.0% |
Exited
| No tracked exits this quarter. |
Full-market context: across ALL 13F filers (SEC structured data, Q1 2026): 186 holders, 27.52M shares, $653.08M reported. This is a different, older period than the tracked-universe figures above and the two are never mixed.
What else this security's tracked holders most often hold — shared-ownership counts, not fundamental relationships.
Open-market purchases (P)
No open-market insider purchases in our coverage window.
Open-market sales (S)
Officer, Director · 3.20K sh · $113,740
Officer, Director · 8.58K sh · $305,156
Officer, Director · 2.72K sh · $96,668
Officer · 1.35K sh · $48,967
Officer · 2.81K sh · $100,350
Officer · 1.03K sh · $35,363
Officer · 5.54K sh · $196,765
Officer, Director · 8.58K sh · $303,166
Officer, Director · 2.72K sh · $96,038
Officer, Director · 3.20K sh · $112,998
Awards, exercises and tax withholding are never counted as buys or sales here. Methodology