Security record · archived quarter
CAI
Caris Life Sciences, Inc. · Healthcare · Biotechnology
79Tracked holders
-1Δ holders
69.03MShares held
$1.86BReported value
+2New positions
−2Exits
All ownership figures: tracked 13F managers only, common-stock positions, reporting period Q4 2025
Ownership over time
Who holds it · Q4 2025
| # | Manager | Shares | Δ shares | Value | Their weight | Held | ||
|---|---|---|---|---|---|---|---|---|
| 1 | Fidelity (FMR) ✦ | 14.22M | +47.6% | $383.60M | 0.0% | ▲ Add | 3 | SEC ↗ ×5 |
| 2 | Coatue Management ✦ | 9.82M | -3.2% | $264.94M | 0.7% | ▼ Trim | 3 | SEC ↗ ×2 |
| 3 | T. Rowe Price ✦ | 4.83M | -30.3% | $130.26M | 0.0% | ▼ Trim | 3 | SEC ↗ ×2 |
| 4 | Neuberger Berman Group LLC | 3.80M | n/a | $102.55M | 0.1% | n/c | 1 | SEC ↗ ×2 |
| 5 | Millennium Management ✦ | 3.65M | -7.2% | $98.55M | 0.1% | ▼ Trim | 3 | SEC ↗ |
| 6 | Citadel Advisors ✦ | 3.11M | New | $84.01M | 0.1% | New | 1 | SEC ↗ ×2 |
| 7 | JPMorgan Chase ✦ | 2.45M | +42.5% | $65.97M | 0.0% | ▲ Add | 2 | SEC ↗ ×5 |
| 8 | BlackRock ✦ (passive) | 2.37M | +266.4% | $63.98M | 0.0% | ▲ Add | 3 | SEC ↗ ×11 |
| 9 | UBS Group AG | 2.18M | n/a | $58.92M | 0.0% | n/c | 1 | SEC ↗ ×4 |
| 10 | Point72 Asset Management ✦ | 1.86M | +656.2% | $50.31M | 0.1% | ▲ Add | 3 | SEC ↗ |
| 11 | Morgan Stanley ✦ | 1.79M | +17.0% | $48.43M | 0.0% | ▲ Add | 2 | SEC ↗ ×13 |
| 12 | Balyasny Asset Management L.P. | 1.66M | n/a | $44.79M | 0.1% | n/c | 1 | SEC ↗ |
| 13 | Ameriprise Financial Inc | 1.51M | n/a | $40.61M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 14 | UBS AM, a distinct business unit of… | 1.47M | n/a | $39.67M | 0.0% | n/c | 1 | SEC ↗ ×4 |
| 15 | Canada Pension Plan Investment Board | 1.46M | n/a | $39.51M | 0.0% | n/c | 1 | SEC ↗ |
| 16 | Clearbridge Investments, LLC | 1.42M | n/a | $38.21M | 0.0% | n/c | 1 | SEC ↗ |
| 17 | FIL Ltd | 1.12M | n/a | $30.29M | 0.0% | n/c | 1 | SEC ↗ |
| 18 | Bank Of America Corp /De/ | 1.12M | n/a | $30.29M | 0.0% | n/c | 1 | SEC ↗ ×5 |
| 19 | Invesco Ltd. | 1.03M | n/a | $27.87M | 0.0% | n/c | 1 | SEC ↗ ×4 |
| 20 | Marshall Wace ✦ | 1.00M | +1108.5% | $27.05M | 0.0% | ▲ Add | 3 | SEC ↗ ×3 |
| 21 | Massachusetts Financial Services Co… | 941.64K | n/a | $25.41M | 0.0% | n/c | 1 | SEC ↗ ×6 |
| 22 | Td Asset Management Inc | 773.85K | n/a | $20.88M | 0.0% | n/c | 1 | SEC ↗ |
| 23 | Bnp Paribas Financial Markets | 685.83K | n/a | $18.50M | 0.0% | n/c | 1 | SEC ↗ |
| 24 | ARK Investment Management ✦ | 408.73K | +66.6% | $11.03M | 0.1% | ▲ Add | 3 | SEC ↗ |
| 25 | Geode Capital Management ✦ (passive) | 372.98K | -6.4% | $10.06M | 0.0% | ▼ Trim | 3 | SEC ↗ ×2 |
| 26 | Goldman Sachs Group ✦ | 350.14K | +24.1% | $9.45M | 0.0% | ▲ Add | 2 | SEC ↗ ×2 |
| 27 | Renaissance Technologies ✦ | 329.90K | +46.6% | $8.90M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 28 | Franklin Resources Inc | 268.62K | n/a | $7.25M | 0.0% | n/c | 1 | SEC ↗ |
| 29 | State Street Global Advisors ✦ (passive) | 260.64K | +67.8% | $7.03M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 30 | Lazard Asset Management Llc | 242.78K | n/a | $6.55M | 0.0% | n/c | 1 | SEC ↗ |
| 31 | Holocene Advisors, LP | 237.90K | n/a | $6.42M | 0.0% | n/c | 1 | SEC ↗ |
| 32 | Qube Research & Technologies Ltd | 206.99K | n/a | $5.58M | 0.0% | n/c | 1 | SEC ↗ |
| 33 | Tudor Investment Corp Et Al | 182.38K | n/a | $4.92M | 0.0% | n/c | 1 | SEC ↗ |
| 34 | Jane Street Group, Llc | 171.00K | n/a | $4.61M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 35 | State Of Wisconsin Investment Board | 150.00K | n/a | $4.05M | 0.0% | n/c | 1 | SEC ↗ |
| 36 | Creative Planning | 149.86K | n/a | $4.04M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 37 | Hrt Financial Lp | 122.94K | n/a | $3.32M | 0.0% | n/c | 1 | SEC ↗ |
| 38 | Norges Bank ✦ (passive) | 110.29K | New | $2.98M | 0.0% | New | 1 | SEC ↗ |
| 39 | Manufacturers Life Insurance… | 101.82K | n/a | $2.78M | 0.0% | n/c | 1 | SEC ↗ |
| 40 | Raymond James Financial Inc | 97.52K | n/a | $2.63M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 41 | TD Waterhouse Canada Inc. | 92.65K | n/a | $2.50M | 0.0% | n/c | 1 | SEC ↗ |
| 42 | Sumitomo Mitsui Trust Group, Inc. | 75.33K | n/a | $2.03M | 0.0% | n/c | 1 | SEC ↗ |
| 43 | Gotham Asset Management ✦ | 67.19K | +102.3% | $1.81M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 44 | Quantinno Capital Management LP | 64.92K | n/a | $1.75M | 0.0% | n/c | 1 | SEC ↗ |
| 45 | Squarepoint Ops LLC | 64.40K | n/a | $1.74M | 0.0% | n/c | 1 | SEC ↗ |
| 46 | Barclays Plc | 54.12K | n/a | $1.46M | 0.0% | n/c | 1 | SEC ↗ |
| 47 | Bank of New York Mellon Corp | 50.40K | n/a | $1.36M | 0.0% | n/c | 1 | SEC ↗ ×7 |
| 48 | Peak6 Llc | 49.60K | n/a | $1.34M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 49 | Northern Trust Corp | 36.95K | n/a | $996,858 | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 50 | The Vanguard Group ✦ (passive) | 33.51K | -80.9% | $903,965 | 0.0% | ▼ Trim | 3 | SEC ↗ ×2 |
| 51 | Envestnet Asset Management Inc | 31.03K | n/a | $837,162 | 0.0% | n/c | 1 | SEC ↗ |
| 52 | Citigroup Inc | 30.73K | n/a | $828,961 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 53 | MIRAE ASSET GLOBAL ETFS HOLDINGS… | 30.16K | n/a | $813,636 | 0.0% | n/c | 1 | SEC ↗ |
| 54 | Group One Trading Llc | 26.34K | n/a | $710,734 | 0.0% | n/c | 1 | SEC ↗ |
| 55 | LPL Financial LLC | 25.71K | n/a | $693,683 | 0.0% | n/c | 1 | SEC ↗ |
| 56 | Deutsche Bank Ag\ | 25.29K | n/a | $682,324 | 0.0% | n/c | 1 | SEC ↗ |
| 57 | Sei Investments Co | 24.45K | n/a | $659,689 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 58 | Rhumbline Advisers | 23.38K | n/a | $630,789 | 0.0% | n/c | 1 | SEC ↗ |
| 59 | Nuveen, LLC | 22.41K | n/a | $604,703 | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 60 | Alliancebernstein L.P. | 20.39K | n/a | $550,041 | 0.0% | n/c | 1 | SEC ↗ |
| 61 | Hsbc Holdings Plc | 19.20K | n/a | $521,304 | 0.0% | n/c | 1 | SEC ↗ ×4 |
| 62 | Mirae Asset Global Investments Co.… | 13.71K | n/a | $369,923 | 0.0% | n/c | 1 | SEC ↗ |
| 63 | Victory Capital Management Inc | 13.26K | n/a | $357,836 | 0.0% | n/c | 1 | SEC ↗ |
| 64 | Us Bancorp \De\ | 12.99K | n/a | $350,443 | 0.0% | n/c | 1 | SEC ↗ ×4 |
| 65 | New York State Common Retirement… | 12.90K | n/a | $348,042 | 0.0% | n/c | 1 | SEC ↗ |
| 66 | ProShare Advisors LLC | 12.46K | n/a | $336,225 | 0.0% | n/c | 1 | SEC ↗ |
| 67 | Royal Bank Of Canada | 9.24K | n/a | $250,000 | 0.0% | n/c | 1 | SEC ↗ ×4 |
| 68 | Wells Fargo & Company/Mn | 8.99K | n/a | $242,685 | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 69 | Legal & General Group Plc | 6.88K | n/a | $185,580 | 0.0% | n/c | 1 | SEC ↗ |
| 70 | Simplex Trading, Llc | 4.60K | n/a | $124,081 | 0.0% | n/c | 1 | SEC ↗ |
| 71 | Osaic Holdings, Inc. | 4.09K | n/a | $110,316 | 0.0% | n/c | 1 | SEC ↗ |
| 72 | Federated Hermes, Inc. | 3.00K | n/a | $80,940 | 0.0% | n/c | 1 | SEC ↗ |
| 73 | Russell Investments Group, Ltd. | 2.00K | n/a | $53,825 | 0.0% | n/c | 1 | SEC ↗ |
| 74 | California State Teachers… | 1.41K | n/a | $38,069 | 0.0% | n/c | 1 | SEC ↗ |
| 75 | Daiwa Securities Group Inc. | 850 | n/a | $23,000 | 0.0% | n/c | 1 | SEC ↗ |
| 76 | Cwm, Llc | 175 | n/a | $5,000 | 0.0% | n/c | 1 | SEC ↗ |
| 77 | Pnc Financial Services Group, Inc. | 175 | n/a | $4,722 | 0.0% | n/c | 1 | SEC ↗ ×4 |
| 78 | Rockefeller Capital Management L.P. | 35 | n/a | $944 | 0.0% | n/c | 1 | SEC ↗ |
| 79 | Jones Financial Companies Lllp | 25 | n/a | $675 | 0.0% | n/c | 1 | SEC ↗ |
“Their weight” = the position's share of that manager's reported 13F equity value: the conviction measure. ✦ = curated manager.
New buyers
| Citadel Advisors | $84.01M | 0.1% |
| Norges Bank | $2.98M | 0.0% |
Exited
| Soros Fund Management | $1.68M | was 0.0% |
| D. E. Shaw & Co. | $1.51M | was 0.0% |
Full-market context: across ALL 13F filers (SEC structured data, Q1 2026): 200 holders, 153.41M shares, $2.53B reported. This is a different, older period than the tracked-universe figures above and the two are never mixed.
Frequently co-owned
What else this security's tracked holders most often hold: shared-ownership counts, not fundamental relationships.
Open-market purchases (P)
No open-market insider purchases in our coverage window.
Open-market sales (S)
Sep 22
Denton John Russel
Officer · 7.50K sh · $238,626
Sep 17
Brille Brian J
Officer, Director · 400.00K sh · $12.13M
Sep 04
Spetzler David Baxley
Officer · 119.21K sh · $2.95M
Sep 03
Spetzler David Baxley
Officer · 393.10K sh · $9.73M
Sep 03
Spetzler David Baxley
Officer · 84.90K sh · $2.15M
Awards, exercises and tax withholding are never counted as buys or sales here. Methodology
Aug 12
SC 13G/A: J H Whitney VI L P
Aug 07
SC 13G/A: TSSP Sub-Fund HoldCo LLC
Provenance: Ownership from parsed 13F common-stock positions (tracked universe, comparable sets for changes); insider rows from Forms 3/4/5; stakes from Schedules 13D/13G; every filing links to its original on SEC EDGAR.
Reporting period: Q4 2025 ·
Methodology ·
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