Security record · archived quarter
ZYME
Zymeworks Inc. · Healthcare · Biotechnology
90Tracked holders
-1Δ holders
25.71MShares held
$677.12MReported value
+0New positions
−1Exits
Momentum inputs (comparable managers):
holder breadth -1.1% ·
share flow -2.6% ·
net new positions -1.1%
· formula
Broad distribution: falling shares and fewer holders
All ownership figures: tracked 13F managers only, common-stock positions, reporting period Q4 2025
Ownership over time
| Quarter | Holders | Δ | Shares | Reported value | New | Exits |
|---|---|---|---|---|---|---|
| Q3 2026 | 2 | 0 | 1.51M | $39.99M | n/a | n/a |
| Q2 2026 | 88 | -1 | 24.75M | $646.12M | +6 | −9 |
| Q1 2026 | 94 | +3 | 24.89M | $623.10M | +9 | −6 |
| Q4 2025 | 90 | -1 | 25.71M | $677.12M | n/a | −1 |
| Q3 2025 | 19 | +2 | 15.73M | $268.60M | +2 | −1 |
| Q2 2025 | 15 | +1 | 10.33M | $129.64M | +1 | n/a |
| Q1 2025 | 11 | 0 | 3.31M | $39.41M | +1 | −1 |
| Q4 2024 | 11 | -2 | 3.00M | $43.95M | n/a | −2 |
| Q3 2024 | 12 | +2 | 2.16M | $27.11M | +2 | n/a |
| Q2 2024 | 10 | n/a | 2.50M | $21.29M | n/a | n/a |
Who holds it · Q4 2025
| # | Manager | Shares | Δ shares | Value | Their weight | Held | ||
|---|---|---|---|---|---|---|---|---|
| 1 | BlackRock ✦ (passive) | 4.60M | +15.2% | $121.00M | 0.0% | ▲ Add | 3 | SEC ↗ ×15 |
| 2 | Morgan Stanley ✦ | 2.59M | -34.9% | $68.28M | 0.0% | ▼ Trim | 2 | SEC ↗ ×6 |
| 3 | The Vanguard Group ✦ (passive) | 2.33M | +8.1% | $61.32M | 0.0% | ▲ Add | 3 | SEC ↗ ×5 |
| 4 | BNP Paribas Asset Management… | 1.82M | n/a | $47.98M | 0.1% | n/c | 1 | SEC ↗ ×3 |
| 5 | Deutsche Bank Ag\ | 1.60M | n/a | $42.02M | 0.0% | n/c | 1 | SEC ↗ ×4 |
| 6 | Dimensional Fund Advisors Lp | 1.16M | n/a | $30.52M | 0.0% | n/c | 1 | SEC ↗ ×5 |
| 7 | State Street Global Advisors ✦ (passive) | 1.04M | -4.0% | $27.32M | 0.0% | ▼ Trim | 5 | SEC ↗ |
| 8 | Arrowstreet Capital ✦ | 700.00K | +123.1% | $18.43M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 9 | Adage Capital Partners ✦ | 663.55K | +17.6% | $17.47M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 10 | Nuveen, LLC | 648.33K | n/a | $17.07M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 11 | Geode Capital Management ✦ (passive) | 647.97K | -4.5% | $17.06M | 0.0% | ▼ Trim | 7 | SEC ↗ ×2 |
| 12 | Assenagon Asset Management S.A. | 647.37K | n/a | $17.05M | 0.0% | n/c | 1 | SEC ↗ |
| 13 | Fidelity (FMR) ✦ | 560.09K | +15838.7% | $14.75M | 0.0% | ▲ Add | 3 | SEC ↗ ×2 |
| 14 | Qube Research & Technologies Ltd | 474.29K | n/a | $12.49M | 0.0% | n/c | 1 | SEC ↗ |
| 15 | Goldman Sachs Group ✦ | 420.21K | -5.3% | $11.06M | 0.0% | ▼ Trim | 2 | SEC ↗ ×2 |
| 16 | Millennium Management ✦ | 381.62K | -65.5% | $10.05M | 0.0% | ▼ Trim | 4 | SEC ↗ |
| 17 | UBS AM, a distinct business unit of… | 320.26K | n/a | $8.43M | 0.0% | n/c | 1 | SEC ↗ ×5 |
| 18 | Northern Trust Corp | 307.98K | n/a | $8.11M | 0.0% | n/c | 1 | SEC ↗ ×6 |
| 19 | UBS Group AG | 278.85K | n/a | $7.34M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 20 | Invesco Ltd. | 257.58K | n/a | $6.78M | 0.0% | n/c | 1 | SEC ↗ ×5 |
| 21 | Citadel Advisors ✦ | 255.35K | +23.4% | $6.72M | 0.0% | ▲ Add | 7 | SEC ↗ ×2 |
| 22 | D. E. Shaw & Co. ✦ | 223.79K | +76.3% | $5.89M | 0.0% | ▲ Add | 7 | SEC ↗ ×2 |
| 23 | Charles Schwab Investment… | 220.91K | n/a | $5.82M | 0.0% | n/c | 1 | SEC ↗ |
| 24 | Renaissance Technologies ✦ | 220.88K | -48.8% | $5.82M | 0.0% | ▼ Trim | 7 | SEC ↗ |
| 25 | Wells Fargo & Company/Mn | 208.31K | n/a | $5.48M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 26 | Raymond James Financial Inc | 187.69K | n/a | $4.94M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 27 | Wellington Management ✦ | 181.71K | +7.7% | $4.78M | 0.0% | ▲ Add | 7 | SEC ↗ ×5 |
| 28 | Susquehanna International Group, Llp | 176.09K | n/a | $4.64M | 0.0% | n/c | 1 | SEC ↗ |
| 29 | Federated Hermes, Inc. | 152.69K | n/a | $4.02M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 30 | Bank of New York Mellon Corp | 128.13K | n/a | $3.37M | 0.0% | n/c | 1 | SEC ↗ ×5 |
| 31 | Hrt Financial Lp | 121.06K | n/a | $3.19M | 0.0% | n/c | 1 | SEC ↗ |
| 32 | Ameriprise Financial Inc | 113.14K | n/a | $2.98M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 33 | Citigroup Inc | 111.21K | n/a | $2.93M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 34 | AQR Capital Management ✦ | 91.08K | -40.3% | $2.40M | 0.0% | ▼ Trim | 7 | SEC ↗ ×6 |
| 35 | Bank Of America Corp /De/ | 89.52K | n/a | $2.36M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 36 | Barclays Plc | 79.97K | n/a | $2.11M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 37 | Stifel Financial Corp | 75.85K | n/a | $2.00M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 38 | State Of Wisconsin Investment Board | 75.57K | n/a | $1.99M | 0.0% | n/c | 1 | SEC ↗ |
| 39 | Rhumbline Advisers | 75.50K | n/a | $1.99M | 0.0% | n/c | 1 | SEC ↗ |
| 40 | Man Group plc | 75.32K | n/a | $1.98M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 41 | Credit Agricole S A | 75.00K | n/a | $1.97M | 0.0% | n/c | 1 | SEC ↗ |
| 42 | Pictet Asset Management Holding SA | 73.63K | n/a | $1.97M | 0.0% | n/c | 1 | SEC ↗ |
| 43 | Swiss National Bank | 74.20K | n/a | $1.95M | 0.0% | n/c | 1 | SEC ↗ |
| 44 | Jane Street Group, Llc | 70.44K | n/a | $1.85M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 45 | Fisher Asset Management ✦ | 68.20K | -5.2% | $1.80M | 0.0% | ▼ Trim | 7 | SEC ↗ |
| 46 | Franklin Resources Inc | 58.99K | n/a | $1.55M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 47 | American Century Companies Inc | 58.83K | n/a | $1.55M | 0.0% | n/c | 1 | SEC ↗ |
| 48 | Russell Investments Group, Ltd. | 58.35K | n/a | $1.54M | 0.0% | n/c | 1 | SEC ↗ ×6 |
| 49 | Royal Bank Of Canada | 55.05K | n/a | $1.45M | 0.0% | n/c | 1 | SEC ↗ ×6 |
| 50 | Alliancebernstein L.P. | 50.03K | n/a | $1.32M | 0.0% | n/c | 1 | SEC ↗ |
| 51 | Simplex Trading, Llc | 48.04K | n/a | $1.26M | 0.0% | n/c | 1 | SEC ↗ |
| 52 | Mackenzie Financial Corp | 45.46K | n/a | $1.20M | 0.0% | n/c | 1 | SEC ↗ |
| 53 | Victory Capital Management Inc | 42.91K | n/a | $1.13M | 0.0% | n/c | 1 | SEC ↗ |
| 54 | Envestnet Asset Management Inc | 40.81K | n/a | $1.07M | 0.0% | n/c | 1 | SEC ↗ |
| 55 | California State Teachers… | 37.76K | n/a | $994,247 | 0.0% | n/c | 1 | SEC ↗ |
| 56 | Hsbc Holdings Plc | 35.74K | n/a | $952,364 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 57 | JPMorgan Chase ✦ | 35.01K | -48.3% | $921,760 | 0.0% | ▼ Trim | 2 | SEC ↗ ×4 |
| 58 | Universal- Beteiligungs- und… | 32.81K | n/a | $864,018 | 0.0% | n/c | 1 | SEC ↗ |
| 59 | Legal & General Group Plc | 32.15K | n/a | $846,483 | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 60 | Tudor Investment Corp Et Al | 30.32K | n/a | $798,431 | 0.0% | n/c | 1 | SEC ↗ |
| 61 | Quantinno Capital Management LP | 28.88K | n/a | $760,489 | 0.0% | n/c | 1 | SEC ↗ |
| 62 | T. Rowe Price ✦ | 28.78K | +7.3% | $758,000 | 0.0% | ▲ Add | 7 | SEC ↗ |
| 63 | Creative Planning | 28.29K | n/a | $744,955 | 0.0% | n/c | 1 | SEC ↗ |
| 64 | Massachusetts Financial Services Co… | 28.08K | n/a | $739,425 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 65 | Commonwealth Equity Services, Llc | 26.09K | n/a | $687,080 | 0.0% | n/c | 1 | SEC ↗ |
| 66 | Bnp Paribas Financial Markets | 23.30K | n/a | $613,436 | 0.0% | n/c | 1 | SEC ↗ |
| 67 | MIRAE ASSET GLOBAL ETFS HOLDINGS… | 23.11K | n/a | $608,460 | 0.0% | n/c | 1 | SEC ↗ |
| 68 | Zurcher Kantonalbank (Zurich… | 20.42K | n/a | $537,685 | 0.0% | n/c | 1 | SEC ↗ |
| 69 | Janus Henderson Group Plc | 18.20K | n/a | $479,115 | 0.0% | n/c | 1 | SEC ↗ |
| 70 | Bank Of Montreal /Can/ | 17.47K | n/a | $459,932 | 0.0% | n/c | 1 | SEC ↗ ×4 |
| 71 | Manufacturers Life Insurance… | 17.43K | n/a | $459,011 | 0.0% | n/c | 1 | SEC ↗ |
| 72 | New York State Common Retirement… | 17.37K | n/a | $457,378 | 0.0% | n/c | 1 | SEC ↗ |
| 73 | State Board Of Administration Of… | 15.34K | n/a | $403,902 | 0.0% | n/c | 1 | SEC ↗ |
| 74 | Lazard Asset Management Llc | 13.78K | n/a | $362,722 | 0.0% | n/c | 1 | SEC ↗ |
| 75 | Walleye Trading LLC | 13.25K | n/a | $348,925 | 0.0% | n/c | 1 | SEC ↗ |
| 76 | Prudential Financial Inc | 12.76K | n/a | $335,839 | 0.0% | n/c | 1 | SEC ↗ |
| 77 | ProShare Advisors LLC | 12.39K | n/a | $326,151 | 0.0% | n/c | 1 | SEC ↗ |
| 78 | Voya Investment Management Llc | 9.23K | n/a | $243,131 | 0.0% | n/c | 1 | SEC ↗ |
| 79 | Group One Trading Llc | 8.84K | n/a | $232,784 | 0.0% | n/c | 1 | SEC ↗ |
| 80 | Allspring Global Investments… | 7.71K | n/a | $205,161 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 81 | Cwm, Llc | 6.97K | n/a | $184,000 | 0.0% | n/c | 1 | SEC ↗ |
| 82 | Mirae Asset Global Investments Co.… | 3.64K | n/a | $95,762 | 0.0% | n/c | 1 | SEC ↗ |
| 83 | Osaic Holdings, Inc. | 2.51K | n/a | $66,086 | 0.0% | n/c | 1 | SEC ↗ |
| 84 | Optiver Holding B.V. | 1.15K | n/a | $30,307 | 0.0% | n/c | 1 | SEC ↗ |
| 85 | Pnc Financial Services Group, Inc. | 781 | n/a | $20,564 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 86 | National Bank Of Canada /Fi/ | 545 | n/a | $14,344 | 0.0% | n/c | 1 | SEC ↗ |
| 87 | TD Waterhouse Canada Inc. | 311 | n/a | $8,186 | 0.0% | n/c | 1 | SEC ↗ |
| 88 | Us Bancorp \De\ | 287 | n/a | $7,557 | 0.0% | n/c | 1 | SEC ↗ |
| 89 | Daiwa Securities Group Inc. | 186 | n/a | $5,000 | 0.0% | n/c | 1 | SEC ↗ |
| 90 | Jones Financial Companies Lllp | 20 | n/a | $527 | 0.0% | n/c | 1 | SEC ↗ |
“Their weight” = the position's share of that manager's reported 13F equity value: the conviction measure. ✦ = curated manager.
New buyers
| No new tracked buyers this quarter. |
Exited
| Marshall Wace | $2.64M | was 0.0% |
Full-market context: across ALL 13F filers (SEC structured data, Q1 2026): 209 holders, 70.12M shares, $1.75B reported. This is a different, older period than the tracked-universe figures above and the two are never mixed.
Frequently co-owned
What else this security's tracked holders most often hold: shared-ownership counts, not fundamental relationships.
Open-market purchases (P)
No open-market insider purchases in our coverage window.
Open-market sales (S)
Oct 09
Schayowitz Adam
Officer · 13.83K sh · $357,557
Awards, exercises and tax withholding are never counted as buys or sales here. Methodology
Provenance: Ownership from parsed 13F common-stock positions (tracked universe, comparable sets for changes); insider rows from Forms 3/4/5; stakes from Schedules 13D/13G; every filing links to its original on SEC EDGAR.
Reporting period: Q4 2025 ·
Methodology ·
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