Security record · archived quarter
WVE
Wave Life Sciences Ltd. · Healthcare · Biotechnology
91Tracked holders
+3Δ holders
75.16MShares held
$544.65MReported value
+10New positions
−7Exits
Momentum inputs (comparable managers):
holder breadth +3.4% ·
share flow -9.6% ·
net new positions +3.3%
· formula
Ownership fragmentation: more holders, smaller aggregate stake
All ownership figures: tracked 13F managers only, common-stock positions, reporting period Q1 2026
Ownership over time
| Quarter | Holders | Δ | Shares | Reported value | New | Exits |
|---|---|---|---|---|---|---|
| Q2 2026 | 87 | 0 | 83.58M | $485.57M | +8 | −9 |
| Q1 2026 | 91 | +3 | 75.16M | $544.65M | +10 | −7 |
| Q4 2025 | 87 | +2 | 83.62M | $1.42B | +4 | −2 |
| Q3 2025 | 17 | 0 | 51.40M | $376.26M | +2 | −3 |
| Q2 2025 | 15 | -1 | 44.33M | $288.15M | +1 | −2 |
| Q1 2025 | 13 | -1 | 25.22M | $203.80M | n/a | −1 |
| Q4 2024 | 14 | -1 | 25.08M | $310.31M | n/a | −1 |
| Q3 2024 | 14 | +2 | 20.71M | $169.87M | +2 | n/a |
| Q2 2024 | 12 | n/a | 14.01M | $69.91M | n/a | n/a |
Who holds it · Q1 2026
| # | Manager | Shares | Δ shares | Value | Their weight | Held | ||
|---|---|---|---|---|---|---|---|---|
| 1 | BlackRock ✦ (passive) | 14.12M | +11.6% | $102.35M | 0.0% | ▲ Add | 4 | SEC ↗ ×16 |
| 2 | T. Rowe Price ✦ | 8.70M | +17.5% | $63.11M | 0.0% | ▲ Add | 8 | SEC ↗ ×2 |
| 3 | Federated Hermes, Inc. | 5.32M | +12.1% | $38.55M | 0.1% | ▲ Add | 2 | SEC ↗ ×3 |
| 4 | Fidelity (FMR) ✦ | 5.19M | -65.7% | $37.65M | 0.0% | ▼ Trim | 4 | SEC ↗ ×4 |
| 5 | PRIMECAP Management ✦ | 4.83M | +18.0% | $35.04M | 0.0% | ▲ Add | 8 | SEC ↗ |
| 6 | State Street Global Advisors ✦ (passive) | 3.67M | +22.6% | $26.64M | 0.0% | ▲ Add | 6 | SEC ↗ |
| 7 | Geode Capital Management ✦ (passive) | 3.58M | +12.9% | $25.95M | 0.0% | ▲ Add | 8 | SEC ↗ ×2 |
| 8 | Citadel Advisors ✦ | 2.20M | +178.9% | $15.97M | 0.0% | ▲ Add | 2 | SEC ↗ ×2 |
| 9 | Two Sigma Investments ✦ | 1.88M | +150.6% | $13.62M | 0.0% | ▲ Add | 8 | SEC ↗ |
| 10 | Marshall Wace ✦ | 1.79M | New | $12.98M | 0.0% | New | 1 | SEC ↗ ×2 |
| 11 | Vanguard Capital Management Llc | 1.61M | n/a | $11.69M | 0.0% | n/c | 1 | SEC ↗ |
| 12 | Squarepoint Ops LLC | 1.46M | +65.5% | $10.60M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 13 | Goldman Sachs Group ✦ | 1.38M | -51.5% | $10.03M | 0.0% | ▼ Trim | 3 | SEC ↗ ×2 |
| 14 | Morgan Stanley ✦ | 1.36M | +232.2% | $9.87M | 0.0% | ▲ Add | 3 | SEC ↗ ×7 |
| 15 | Schroder Investment Management Group | 1.44M | n/a | $9.54M | 0.0% | n/c | 1 | SEC ↗ |
| 16 | Northern Trust Corp | 1.19M | +15.1% | $8.62M | 0.0% | ▲ Add | 2 | SEC ↗ ×5 |
| 17 | Charles Schwab Investment… | 1.18M | -1.0% | $8.55M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 18 | Pictet Asset Management Holding SA | 1.15M | +42.6% | $8.20M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 19 | Adage Capital Partners ✦ | 1.00M | -89.8% | $7.25M | 0.0% | ▼ Trim | 8 | SEC ↗ |
| 20 | Millennium Management ✦ | 972.24K | +66.3% | $7.05M | 0.0% | ▲ Add | 8 | SEC ↗ |
| 21 | Nuveen, LLC | 657.72K | +97.7% | $4.77M | 0.0% | ▲ Add | 2 | SEC ↗ ×3 |
| 22 | Connor, Clark & Lunn Investment… | 624.74K | +804.4% | $4.53M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 23 | JPMorgan Chase ✦ | 670.17K | -24.9% | $4.44M | 0.0% | ▼ Trim | 3 | SEC ↗ ×6 |
| 24 | Renaissance Technologies ✦ | 597.22K | +152.6% | $4.33M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 25 | Aberdeen Group plc | 550.00K | New | $3.99M | 0.0% | New | 1 | SEC ↗ |
| 26 | UBS Group AG | 539.00K | +100.6% | $3.91M | 0.0% | ▲ Add | 2 | SEC ↗ ×3 |
| 27 | Citigroup Inc | 501.48K | +972.5% | $3.64M | 0.0% | ▲ Add | 2 | SEC ↗ ×2 |
| 28 | AQR Capital Management ✦ | 451.19K | +122.6% | $3.27M | 0.0% | ▲ Add | 3 | SEC ↗ ×8 |
| 29 | Universal- Beteiligungs- und… | 415.46K | +1.0% | $3.01M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 30 | Wellington Management ✦ | 373.79K | +2.3% | $2.71M | 0.0% | ▲ Add | 8 | SEC ↗ ×5 |
| 31 | Bank of New York Mellon Corp | 361.20K | +12.4% | $2.62M | 0.0% | ▲ Add | 2 | SEC ↗ ×4 |
| 32 | Hrt Financial Lp | 341.98K | +14.1% | $2.48M | 0.0% | ▲ Add | 2 | SEC ↗ ×2 |
| 33 | Td Asset Management Inc | 338.83K | +34.4% | $2.46M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 34 | Alliancebernstein L.P. | 125.10K | +11.7% | $2.13M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 35 | Bnp Paribas Financial Markets | 281.02K | +242.6% | $2.04M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 36 | Susquehanna International Group, Llp | 259.82K | -31.4% | $1.88M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 37 | Manufacturers Life Insurance… | 240.98K | +31.9% | $1.75M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 38 | Bank Of America Corp /De/ | 236.76K | +29.5% | $1.72M | 0.0% | ▲ Add | 2 | SEC ↗ ×3 |
| 39 | UBS AM, a distinct business unit of… | 225.11K | +36.5% | $1.63M | 0.0% | ▲ Add | 2 | SEC ↗ ×9 |
| 40 | Swiss National Bank | 219.70K | 0.0% | $1.59M | 0.0% | Held | 2 | SEC ↗ |
| 41 | Balyasny Asset Management L.P. | 211.07K | New | $1.53M | 0.0% | New | 1 | SEC ↗ |
| 42 | Invesco Ltd. | 199.74K | +11.0% | $1.45M | 0.0% | ▲ Add | 2 | SEC ↗ ×5 |
| 43 | Barclays Plc | 189.87K | -31.4% | $1.38M | 0.0% | ▼ Trim | 2 | SEC ↗ ×3 |
| 44 | Duquesne Family Office ✦ | 173.00K | 0.0% | $1.25M | 0.0% | Held | 2 | SEC ↗ |
| 45 | Rhumbline Advisers | 167.53K | +18.1% | $1.21M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 46 | Qube Research & Technologies Ltd | 155.92K | New | $1.13M | 0.0% | New | 1 | SEC ↗ |
| 47 | MIRAE ASSET GLOBAL ETFS HOLDINGS… | 150.37K | +11.8% | $1.09M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 48 | California State Teachers… | 145.21K | +34.9% | $1.05M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 49 | Wells Fargo & Company/Mn | 136.17K | -32.2% | $987,255 | 0.0% | ▼ Trim | 2 | SEC ↗ ×3 |
| 50 | Deutsche Bank Ag\ | 114.11K | +19.2% | $827,298 | 0.0% | ▲ Add | 2 | SEC ↗ ×2 |
| 51 | State Of Wisconsin Investment Board | 108.16K | +24.1% | $784,189 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 52 | Tudor Investment Corp Et Al | 97.90K | New | $709,775 | 0.0% | New | 1 | SEC ↗ |
| 53 | Simplex Trading, Llc | 89.26K | +322.5% | $647,156 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 54 | Nomura Asset Management… | 81.95K | -59.8% | $594,000 | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 55 | Sei Investments Co | 80.16K | +47.2% | $581,167 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 56 | Legal & General Group Plc | 79.05K | -15.9% | $572,746 | 0.0% | ▼ Trim | 2 | SEC ↗ ×3 |
| 57 | D. E. Shaw & Co. ✦ | 72.31K | -72.8% | $524,211 | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 58 | Voya Investment Management Llc | 69.09K | -38.8% | $500,918 | 0.0% | ▼ Trim | 2 | SEC ↗ ×2 |
| 59 | Man Group plc | 64.04K | +103.8% | $464,261 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 60 | Russell Investments Group, Ltd. | 58.05K | +16.3% | $420,876 | 0.0% | ▲ Add | 2 | SEC ↗ ×4 |
| 61 | Zurcher Kantonalbank (Zurich… | 51.95K | -17.2% | $376,674 | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 62 | Janus Henderson Group Plc | 51.70K | 0.0% | $374,567 | 0.0% | Held | 2 | SEC ↗ |
| 63 | Quantinno Capital Management LP | 47.88K | +23.0% | $347,166 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 64 | Ameriprise Financial Inc | 40.37K | -89.9% | $292,712 | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 65 | Raymond James Financial Inc | 39.62K | -64.4% | $287,281 | 0.0% | ▼ Trim | 2 | SEC ↗ ×2 |
| 66 | Envestnet Asset Management Inc | 38.55K | -3.2% | $279,459 | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 67 | New York State Common Retirement… | 35.92K | 0.0% | $260,420 | 0.0% | Held | 2 | SEC ↗ |
| 68 | Mitsubishi UFJ Asset Management… | 33.02K | -2.4% | $239,417 | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 69 | HighTower Advisors, LLC | 29.23K | +28.0% | $211,932 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 70 | ProShare Advisors LLC | 28.68K | +0.5% | $207,915 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 71 | Osaic Holdings, Inc. | 27.67K | +2254.6% | $200,578 | 0.0% | ▲ Add | 2 | SEC ↗ ×2 |
| 72 | Creative Planning | 27.57K | +52.2% | $199,912 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 73 | Victory Capital Management Inc | 24.79K | +57.7% | $179,749 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 74 | Prudential Financial Inc | 21.09K | New | $152,903 | 0.0% | New | 1 | SEC ↗ |
| 75 | Mariner, LLC | 20.89K | New | $151,278 | 0.0% | New | 1 | SEC ↗ |
| 76 | State Board Of Administration Of… | 16.95K | 0.0% | $122,888 | 0.0% | Held | 2 | SEC ↗ |
| 77 | Royal Bank Of Canada | 16.70K | -28.0% | $122,000 | 0.0% | ▼ Trim | 2 | SEC ↗ ×3 |
| 78 | Canada Pension Plan Investment Board | 16.80K | New | $121,800 | 0.0% | New | 1 | SEC ↗ |
| 79 | Walleye Trading LLC | 16.29K | -51.0% | $118,088 | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 80 | Cwm, Llc | 14.85K | +601.5% | $107,670 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 81 | First Trust Advisors Lp | 13.52K | +15.7% | $98,005 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 82 | Mercer Global Advisors Inc /Adv | 12.63K | New | $91,539 | 0.0% | New | 1 | SEC ↗ |
| 83 | LPL Financial LLC | 10.37K | New | $75,204 | 0.0% | New | 1 | SEC ↗ |
| 84 | Mirae Asset Global Investments Co.… | 9.82K | +20.9% | $71,188 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 85 | Us Bancorp \De\ | 7.03K | +12.2% | $50,932 | 0.0% | ▲ Add | 2 | SEC ↗ ×2 |
| 86 | Group One Trading Llc | 6.26K | -90.8% | $45,385 | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 87 | Rockefeller Capital Management L.P. | 2.27K | +163.2% | $16,428 | 0.0% | ▲ Add | 2 | SEC ↗ ×3 |
| 88 | Jones Financial Companies Lllp | 940 | +88.0% | $5,983 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 89 | Optiver Holding B.V. | 480 | +86.0% | $3,480 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 90 | Pnc Financial Services Group, Inc. | 27 | +170.0% | $196 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 91 | Nomura Asset Management Co Ltd | 0 | n/a | $0 | 0.0% | Held | 2 | SEC ↗ |
“Their weight” = the position's share of that manager's reported 13F equity value: the conviction measure. ✦ = curated manager.
New buyers
| Marshall Wace | $12.98M | 0.0% |
| Aberdeen Group plc | $3.99M | 0.0% |
| Balyasny Asset Management L.P. | $1.53M | 0.0% |
| Qube Research & Technologies… | $1.13M | 0.0% |
| Tudor Investment Corp Et Al | $709,775 | 0.0% |
| Prudential Financial Inc | $152,903 | 0.0% |
| Mariner, LLC | $151,278 | 0.0% |
| Canada Pension Plan… | $121,800 | 0.0% |
| Mercer Global Advisors Inc… | $91,539 | 0.0% |
| LPL Financial LLC | $75,204 | 0.0% |
Exited
| Loomis Sayles & Co L P | $34.68M | was 0.0% |
| Principal Financial Group Inc | $2.89M | was 0.0% |
| Jane Street Group, Llc | $1.89M | was 0.0% |
| LMR Partners LLP | $1.70M | was 0.0% |
| Hsbc Holdings Plc | $581,738 | was 0.0% |
| Allianz Asset Management GmbH | $374,000 | was 0.0% |
| Daiwa Securities Group Inc. | $9,000 | was 0.0% |
Full-market context: across ALL 13F filers (SEC structured data, Q1 2026): 230 holders, 172.04M shares, $1.17B reported. This is a different, older period than the tracked-universe figures above and the two are never mixed.
Frequently co-owned
What else this security's tracked holders most often hold: shared-ownership counts, not fundamental relationships.
Open-market purchases (P)
No open-market insider purchases in our coverage window.
Open-market sales (S)
Aug 12
Rawcliffe Adrian
Director · 12.70K sh · $67,183
Aug 11
TAKANASHI KEN
Director · 3.86K sh · $23,223
Aug 11
Tan Aik Na
Director · 432 sh · $2,596
Aug 11
Wagner Heidi L
Director · 7.00K sh · $42,070
Awards, exercises and tax withholding are never counted as buys or sales here. Methodology
Aug 11
SC 13D/A: RA CAPITAL MANAGEMENT, L.P.
16.8% of class · View original SEC filing ↗
Provenance: Ownership from parsed 13F common-stock positions (tracked universe, comparable sets for changes); insider rows from Forms 3/4/5; stakes from Schedules 13D/13G; every filing links to its original on SEC EDGAR.
Reporting period: Q1 2026 ·
Methodology ·
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