Security record · archived quarter
WVE
Wave Life Sciences Ltd. · Healthcare · Biotechnology
87Tracked holders
+2Δ holders
83.62MShares held
$1.42BReported value
+4New positions
−2Exits
Momentum inputs (comparable managers):
holder breadth +2.4% ·
share flow +21.7% ·
net new positions +2.3%
· formula
Broad accumulation: rising shares across more holders
All ownership figures: tracked 13F managers only, common-stock positions, reporting period Q4 2025
Ownership over time
| Quarter | Holders | Δ | Shares | Reported value | New | Exits |
|---|---|---|---|---|---|---|
| Q2 2026 | 87 | 0 | 83.58M | $485.57M | +8 | −9 |
| Q1 2026 | 91 | +3 | 75.16M | $544.65M | +10 | −7 |
| Q4 2025 | 87 | +2 | 83.62M | $1.42B | +4 | −2 |
| Q3 2025 | 17 | 0 | 51.40M | $376.26M | +2 | −3 |
| Q2 2025 | 15 | -1 | 44.33M | $288.15M | +1 | −2 |
| Q1 2025 | 13 | -1 | 25.22M | $203.80M | n/a | −1 |
| Q4 2024 | 14 | -1 | 25.08M | $310.31M | n/a | −1 |
| Q3 2024 | 14 | +2 | 20.71M | $169.87M | +2 | n/a |
| Q2 2024 | 12 | n/a | 14.01M | $69.91M | n/a | n/a |
Who holds it · Q4 2025
| # | Manager | Shares | Δ shares | Value | Their weight | Held | ||
|---|---|---|---|---|---|---|---|---|
| 1 | Fidelity (FMR) ✦ | 15.14M | +195.0% | $257.31M | 0.0% | ▲ Add | 3 | SEC ↗ ×4 |
| 2 | BlackRock ✦ (passive) | 12.65M | +21.3% | $215.03M | 0.0% | ▲ Add | 3 | SEC ↗ ×14 |
| 3 | Adage Capital Partners ✦ | 9.79M | -32.8% | $166.36M | 0.3% | ▼ Trim | 7 | SEC ↗ |
| 4 | T. Rowe Price ✦ | 7.41M | +83.2% | $125.93M | 0.0% | ▲ Add | 7 | SEC ↗ ×2 |
| 5 | Federated Hermes, Inc. | 4.74M | n/a | $80.66M | 0.1% | n/c | 1 | SEC ↗ |
| 6 | PRIMECAP Management ✦ | 4.10M | +115.7% | $69.62M | 0.1% | ▲ Add | 7 | SEC ↗ |
| 7 | The Vanguard Group ✦ (passive) | 3.57M | +13.8% | $60.75M | 0.0% | ▲ Add | 3 | SEC ↗ ×5 |
| 8 | Geode Capital Management ✦ (passive) | 3.17M | +8.6% | $53.90M | 0.0% | ▲ Add | 7 | SEC ↗ ×2 |
| 9 | State Street Global Advisors ✦ (passive) | 3.00M | +5.3% | $50.93M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 10 | Goldman Sachs Group ✦ | 2.85M | +34.3% | $48.52M | 0.0% | ▲ Add | 2 | SEC ↗ ×2 |
| 11 | Loomis Sayles & Co L P | 2.04M | n/a | $34.68M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 12 | Charles Schwab Investment… | 1.19M | n/a | $20.25M | 0.0% | n/c | 1 | SEC ↗ |
| 13 | Northern Trust Corp | 1.03M | n/a | $17.56M | 0.0% | n/c | 1 | SEC ↗ ×6 |
| 14 | JPMorgan Chase ✦ | 892.89K | -48.1% | $15.18M | 0.0% | ▼ Trim | 2 | SEC ↗ ×6 |
| 15 | Squarepoint Ops LLC | 883.59K | n/a | $15.02M | 0.0% | n/c | 1 | SEC ↗ |
| 16 | Pictet Asset Management Holding SA | 805.90K | n/a | $13.83M | 0.0% | n/c | 1 | SEC ↗ |
| 17 | Citadel Advisors ✦ | 789.96K | New | $13.43M | 0.0% | New | 1 | SEC ↗ ×2 |
| 18 | Two Sigma Investments ✦ | 749.45K | +33.1% | $12.74M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 19 | Millennium Management ✦ | 584.63K | +49.6% | $9.94M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 20 | Universal- Beteiligungs- und… | 411.49K | n/a | $7.00M | 0.0% | n/c | 1 | SEC ↗ |
| 21 | Morgan Stanley ✦ | 409.66K | -19.2% | $6.96M | 0.0% | ▼ Trim | 2 | SEC ↗ ×7 |
| 22 | Ameriprise Financial Inc | 398.42K | n/a | $6.77M | 0.0% | n/c | 1 | SEC ↗ |
| 23 | Susquehanna International Group, Llp | 378.99K | n/a | $6.44M | 0.0% | n/c | 1 | SEC ↗ |
| 24 | Wellington Management ✦ | 365.24K | -15.0% | $6.21M | 0.0% | ▼ Trim | 7 | SEC ↗ ×3 |
| 25 | Nuveen, LLC | 332.74K | n/a | $5.66M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 26 | Bank of New York Mellon Corp | 321.44K | n/a | $5.46M | 0.0% | n/c | 1 | SEC ↗ ×4 |
| 27 | Hrt Financial Lp | 299.72K | n/a | $5.09M | 0.0% | n/c | 1 | SEC ↗ |
| 28 | Barclays Plc | 276.78K | n/a | $4.71M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 29 | UBS Group AG | 268.72K | n/a | $4.57M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 30 | D. E. Shaw & Co. ✦ | 266.13K | New | $4.52M | 0.0% | New | 1 | SEC ↗ |
| 31 | Td Asset Management Inc | 252.16K | n/a | $4.29M | 0.0% | n/c | 1 | SEC ↗ |
| 32 | Renaissance Technologies ✦ | 236.42K | New | $4.02M | 0.0% | New | 1 | SEC ↗ |
| 33 | Swiss National Bank | 219.70K | n/a | $3.73M | 0.0% | n/c | 1 | SEC ↗ |
| 34 | Nomura Asset Management… | 203.74K | n/a | $3.46M | 0.0% | n/c | 1 | SEC ↗ |
| 35 | AQR Capital Management ✦ | 202.72K | +1794.9% | $3.45M | 0.0% | ▲ Add | 2 | SEC ↗ ×5 |
| 36 | Wells Fargo & Company/Mn | 200.89K | n/a | $3.42M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 37 | Manufacturers Life Insurance… | 182.73K | n/a | $3.13M | 0.0% | n/c | 1 | SEC ↗ |
| 38 | Bank Of America Corp /De/ | 182.85K | n/a | $3.11M | 0.0% | n/c | 1 | SEC ↗ ×4 |
| 39 | Invesco Ltd. | 179.93K | n/a | $3.06M | 0.0% | n/c | 1 | SEC ↗ ×5 |
| 40 | Duquesne Family Office ✦ | 173.00K | New | $2.94M | 0.1% | New | 1 | SEC ↗ |
| 41 | Principal Financial Group Inc | 170.17K | n/a | $2.89M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 42 | UBS AM, a distinct business unit of… | 164.99K | n/a | $2.80M | 0.0% | n/c | 1 | SEC ↗ ×6 |
| 43 | Rhumbline Advisers | 141.90K | n/a | $2.41M | 0.0% | n/c | 1 | SEC ↗ |
| 44 | MIRAE ASSET GLOBAL ETFS HOLDINGS… | 134.56K | n/a | $2.29M | 0.0% | n/c | 1 | SEC ↗ |
| 45 | Voya Investment Management Llc | 112.88K | n/a | $1.92M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 46 | Alliancebernstein L.P. | 112.03K | n/a | $1.90M | 0.0% | n/c | 1 | SEC ↗ |
| 47 | Raymond James Financial Inc | 111.17K | n/a | $1.89M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 48 | Jane Street Group, Llc | 110.92K | n/a | $1.89M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 49 | California State Teachers… | 107.68K | n/a | $1.83M | 0.0% | n/c | 1 | SEC ↗ |
| 50 | LMR Partners LLP | 100.00K | n/a | $1.70M | 0.0% | n/c | 1 | SEC ↗ |
| 51 | Deutsche Bank Ag\ | 95.71K | n/a | $1.63M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 52 | Legal & General Group Plc | 93.98K | n/a | $1.60M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 53 | State Of Wisconsin Investment Board | 87.14K | n/a | $1.48M | 0.0% | n/c | 1 | SEC ↗ |
| 54 | Bnp Paribas Financial Markets | 82.02K | n/a | $1.39M | 0.0% | n/c | 1 | SEC ↗ |
| 55 | Connor, Clark & Lunn Investment… | 69.08K | n/a | $1.17M | 0.0% | n/c | 1 | SEC ↗ |
| 56 | Group One Trading Llc | 67.97K | n/a | $1.16M | 0.0% | n/c | 1 | SEC ↗ |
| 57 | Zurcher Kantonalbank (Zurich… | 62.73K | n/a | $1.07M | 0.0% | n/c | 1 | SEC ↗ |
| 58 | Sei Investments Co | 54.46K | n/a | $925,769 | 0.0% | n/c | 1 | SEC ↗ |
| 59 | Janus Henderson Group Plc | 51.70K | n/a | $877,608 | 0.0% | n/c | 1 | SEC ↗ |
| 60 | Russell Investments Group, Ltd. | 49.90K | n/a | $848,351 | 0.0% | n/c | 1 | SEC ↗ ×6 |
| 61 | Citigroup Inc | 46.76K | n/a | $794,903 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 62 | Envestnet Asset Management Inc | 39.82K | n/a | $676,940 | 0.0% | n/c | 1 | SEC ↗ |
| 63 | Quantinno Capital Management LP | 38.92K | n/a | $661,725 | 0.0% | n/c | 1 | SEC ↗ |
| 64 | New York State Common Retirement… | 35.92K | n/a | $610,640 | 0.0% | n/c | 1 | SEC ↗ |
| 65 | Hsbc Holdings Plc | 33.98K | n/a | $581,738 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 66 | Walleye Trading LLC | 33.24K | n/a | $565,097 | 0.0% | n/c | 1 | SEC ↗ |
| 67 | Mitsubishi UFJ Asset Management… | 33.84K | n/a | $539,732 | 0.0% | n/c | 1 | SEC ↗ |
| 68 | Man Group plc | 31.42K | n/a | $534,106 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 69 | ProShare Advisors LLC | 28.54K | n/a | $485,112 | 0.0% | n/c | 1 | SEC ↗ |
| 70 | Royal Bank Of Canada | 23.21K | n/a | $396,000 | 0.0% | n/c | 1 | SEC ↗ ×5 |
| 71 | HighTower Advisors, LLC | 22.83K | n/a | $388,110 | 0.0% | n/c | 1 | SEC ↗ |
| 72 | Allianz Asset Management GmbH | 22.00K | n/a | $374,000 | 0.0% | n/c | 1 | SEC ↗ |
| 73 | Simplex Trading, Llc | 21.13K | n/a | $359,142 | 0.0% | n/c | 1 | SEC ↗ |
| 74 | Creative Planning | 18.12K | n/a | $308,057 | 0.0% | n/c | 1 | SEC ↗ |
| 75 | State Board Of Administration Of… | 16.95K | n/a | $288,150 | 0.0% | n/c | 1 | SEC ↗ |
| 76 | Victory Capital Management Inc | 15.72K | n/a | $267,257 | 0.0% | n/c | 1 | SEC ↗ |
| 77 | First Trust Advisors Lp | 11.69K | n/a | $198,696 | 0.0% | n/c | 1 | SEC ↗ |
| 78 | Mirae Asset Global Investments Co.… | 8.12K | n/a | $138,108 | 0.0% | n/c | 1 | SEC ↗ |
| 79 | Us Bancorp \De\ | 6.26K | n/a | $106,471 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 80 | Cwm, Llc | 2.12K | n/a | $36,000 | 0.0% | n/c | 1 | SEC ↗ |
| 81 | Osaic Holdings, Inc. | 1.18K | n/a | $19,975 | 0.0% | n/c | 1 | SEC ↗ |
| 82 | Rockefeller Capital Management L.P. | 861 | n/a | $14,637 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 83 | Daiwa Securities Group Inc. | 503 | n/a | $9,000 | 0.0% | n/c | 1 | SEC ↗ |
| 84 | Jones Financial Companies Lllp | 500 | n/a | $8,500 | 0.0% | n/c | 1 | SEC ↗ |
| 85 | Optiver Holding B.V. | 258 | n/a | $4,386 | 0.0% | n/c | 1 | SEC ↗ |
| 86 | Pnc Financial Services Group, Inc. | 10 | n/a | $170 | 0.0% | n/c | 1 | SEC ↗ |
| 87 | Nomura Asset Management Co Ltd | 0 | n/a | $0 | 0.0% | n/c | 1 | SEC ↗ |
“Their weight” = the position's share of that manager's reported 13F equity value: the conviction measure. ✦ = curated manager.
New buyers
| Citadel Advisors | $13.43M | 0.0% |
| D. E. Shaw & Co. | $4.52M | 0.0% |
| Renaissance Technologies | $4.02M | 0.0% |
| Duquesne Family Office | $2.94M | 0.1% |
Exited
| Point72 Asset Management | $4.86M | was 0.0% |
| Marshall Wace | $102,480 | was 0.0% |
Full-market context: across ALL 13F filers (SEC structured data, Q1 2026): 230 holders, 172.04M shares, $1.17B reported. This is a different, older period than the tracked-universe figures above and the two are never mixed.
Frequently co-owned
What else this security's tracked holders most often hold: shared-ownership counts, not fundamental relationships.
Open-market purchases (P)
No open-market insider purchases in our coverage window.
Open-market sales (S)
Aug 12
Rawcliffe Adrian
Director · 12.70K sh · $67,183
Aug 11
TAKANASHI KEN
Director · 3.86K sh · $23,223
Aug 11
Tan Aik Na
Director · 432 sh · $2,596
Aug 11
Wagner Heidi L
Director · 7.00K sh · $42,070
Awards, exercises and tax withholding are never counted as buys or sales here. Methodology
Aug 11
SC 13D/A: RA CAPITAL MANAGEMENT, L.P.
16.8% of class · View original SEC filing ↗
Provenance: Ownership from parsed 13F common-stock positions (tracked universe, comparable sets for changes); insider rows from Forms 3/4/5; stakes from Schedules 13D/13G; every filing links to its original on SEC EDGAR.
Reporting period: Q4 2025 ·
Methodology ·
Get this via the API