Registro do valor mobiliário

UPB

Upstream Bio, Inc. · Healthcare · Biotechnology

4.70 +3.3% cap. de mercado $255.77M cotação com atraso (FMP) · em Oct 11 03:53 UTC — independente dos dados de arquivo abaixo

Q2 2026 Q1 2026 Q4 2025 Q3 2025 Q2 2025 Q1 2025 Q4 2024

66Detentores rastreados

+3Δ titulares

29.87MAções mantidas

$206.85MValor reportado

+14Novas posições

−10Saídas

Rising Como estes valores são calculados → Explicar isso no Research Desk →

Dados de momentum (gestores comparáveis): amplitude de detentores +4.8% · fluxo de ações +6.5% · novas posições líquidas +6.1% — fórmula
Acumulação ampla — aumento de ações entre um número maior de detentores

Todos os dados de participação: apenas gestores 13F rastreados, posições em ações ordinárias, período de referência Q2 2026

Participação ao longo do tempo

Trimestre	Detentores	Δ	Ações	Valor reportado	Novo	Saídas
Q2 2026	66	+3	29.87M	$206.85M	+14	−10
Q1 2026	64	+3	24.32M	$219.33M	+14	−12
Q4 2025	62	+3	27.51M	$746.80M	+4	—
Q3 2025	14	+2	17.53M	$329.70M	+2	−1
Q2 2025	10	-1	15.87M	$174.20M	+1	−2
Q1 2025	8	+1	3.40M	$20.78M	+3	−2
Q4 2024	7	+6	3.71M	$60.61M	+6	—

Número de detentores

Quem detém · Q2 2026

#	Gestor	Ações	Δ ações	Valor	Seu peso		Detido
1	Fidelity (FMR) ✦	8.16M	+0.8%	$56.49M	0.0%	▲ Add	5	SEC ↗ ×3
2	Norges Bank ✦ (passivo)	3.77M	Novo	$26.08M	0.0%	New	1	SEC ↗
3	BlackRock ✦ (passivo)	3.75M	+11.3%	$25.97M	0.0%	▲ Add	5	SEC ↗ ×12
4	Vanguard Capital Management Llc	1.88M	+0.2%	$12.99M	0.0%	▲ Add	2	SEC ↗
5	Millennium Management ✦	1.14M	+22.0%	$7.91M	0.0%	▲ Add	4	SEC ↗
6	D. E. Shaw & Co. ✦	1.04M	+26.3%	$7.17M	0.0%	▲ Add	3	SEC ↗ ×2
7	JPMorgan Chase ✦	1.01M	+118.6%	$7.01M	0.0%	▲ Add	4	SEC ↗ ×4
8	Qube Research & Technologies Ltd	978.50K	+58.0%	$6.77M	0.0%	▲ Add	2	SEC ↗
9	Geode Capital Management ✦ (passivo)	931.26K	-2.0%	$6.45M	0.0%	▼ Trim	7	SEC ↗ ×2
10	State Street Global Advisors ✦ (passivo)	766.32K	+8.6%	$5.30M	0.0%	▲ Add	7	SEC ↗
11	AQR Capital Management ✦	544.87K	+655.0%	$3.77M	0.0%	▲ Add	6	SEC ↗ ×6
12	Morgan Stanley ✦	524.63K	-5.1%	$3.63M	0.0%	▼ Trim	4	SEC ↗ ×6
13	Bnp Paribas Financial Markets	511.55K	+306.0%	$3.54M	0.0%	▲ Add	3	SEC ↗
14	Point72 Asset Management ✦	453.01K	+154.3%	$3.13M	0.0%	▲ Add	2	SEC ↗
15	Bank Of America Corp /De/	391.76K	+708.4%	$2.71M	0.0%	▲ Add	3	SEC ↗
16	Dimensional Fund Advisors Lp	381.61K	+377.0%	$2.64M	0.0%	▲ Add	2	SEC ↗ ×4
17	Arrowstreet Capital ✦	357.76K	+93.3%	$2.48M	0.0%	▲ Add	2	SEC ↗
18	Wellington Management ✦	342.35K	0.0%	$2.37M	0.0%	Held	7	SEC ↗
19	Northern Trust Corp	297.35K	+13.9%	$2.06M	0.0%	▲ Add	3	SEC ↗ ×5
20	Squarepoint Ops LLC	290.90K	+551.9%	$2.01M	0.0%	▲ Add	2	SEC ↗
21	Charles Schwab Investment…	262.46K	+1.8%	$1.82M	0.0%	▲ Add	3	SEC ↗
22	Goldman Sachs Group ✦	246.92K	-22.0%	$1.71M	0.0%	▼ Trim	4	SEC ↗
23	Deutsche Bank Ag\	241.45K	+33.5%	$1.67M	0.0%	▲ Add	3	SEC ↗ ×2
24	UBS Group AG	234.71K	+1.5%	$1.62M	0.0%	▲ Add	3	SEC ↗ ×2
25	Hrt Financial Lp	170.59K	Novo	$1.18M	0.0%	New	1	SEC ↗
26	Renaissance Technologies ✦	131.30K	+111.4%	$908,596	0.0%	▲ Add	3	SEC ↗
27	Bank of New York Mellon Corp	85.75K	+5.4%	$593,369	0.0%	▲ Add	3	SEC ↗ ×3
28	Nuveen, LLC	84.77K	+12.2%	$586,608	0.0%	▲ Add	3	SEC ↗ ×2
29	American Century Companies Inc	78.19K	-10.8%	$541,102	0.0%	▼ Trim	3	SEC ↗
30	Man Group plc	73.82K	+249.0%	$510,855	0.0%	▲ Add	2	SEC ↗
31	Alliancebernstein L.P.	51.68K	+66.7%	$465,120	0.0%	▲ Add	3	SEC ↗
32	Quantinno Capital Management LP	54.84K	+11.0%	$379,479	0.0%	▲ Add	3	SEC ↗
33	Invesco Ltd.	53.40K	+31.8%	$369,508	0.0%	▲ Add	3	SEC ↗ ×5
34	Swiss National Bank	48.10K	0.0%	$332,852	0.0%	Held	3	SEC ↗
35	Russell Investments Group, Ltd.	47.54K	+1203.6%	$329,000	0.0%	▲ Add	3	SEC ↗ ×6
36	Allspring Global Investments…	43.18K	Novo	$298,819	0.0%	New	1	SEC ↗
37	Rhumbline Advisers	42.38K	+2.9%	$293,288	0.0%	▲ Add	3	SEC ↗
38	Two Sigma Investments ✦	42.33K	Novo	$292,889	0.0%	New	1	SEC ↗
39	Citigroup Inc	40.34K	+698.0%	$279,145	0.0%	▲ Add	3	SEC ↗ ×2
40	Mariner, LLC	33.14K	+21.3%	$229,337	0.0%	▲ Add	3	SEC ↗
41	Wells Fargo & Company/Mn	29.50K	+60.3%	$204,119	0.0%	▲ Add	3	SEC ↗
42	Barclays Plc	29.21K	+18.2%	$202,120	0.0%	▲ Add	3	SEC ↗ ×2
43	Creative Planning	28.48K	+162.5%	$197,102	0.0%	▲ Add	3	SEC ↗ ×2
44	T. Rowe Price ✦	28.06K	+6.1%	$195,000	0.0%	▲ Add	5	SEC ↗
45	Sei Investments Co	20.03K	Novo	$138,580	0.0%	New	1	SEC ↗
46	State Of Wisconsin Investment Board	17.07K	-59.0%	$118,090	0.0%	▼ Trim	2	SEC ↗
47	MIRAE ASSET GLOBAL ETFS HOLDINGS…	16.22K	+3.9%	$112,222	0.0%	▲ Add	3	SEC ↗
48	Manufacturers Life Insurance…	15.73K	+2.6%	$108,886	0.0%	▲ Add	3	SEC ↗
49	Jane Street Group, Llc	15.59K	Novo	$107,910	0.0%	New	1	SEC ↗ ×2
50	Mercer Global Advisors Inc /Adv	13.35K	Novo	$92,396	0.0%	New	1	SEC ↗
51	Legal & General Group Plc	12.56K	+30.7%	$86,922	0.0%	▲ Add	3	SEC ↗ ×3
52	Canada Pension Plan Investment Board	11.50K	Novo	$79,580	0.0%	New	1	SEC ↗
53	Hsbc Holdings Plc	10.79K	-98.3%	$77,602	0.0%	▼ Trim	2	SEC ↗
54	Wealth Enhancement Advisory…	10.02K	Novo	$75,428	0.0%	New	1	SEC ↗
55	Ameriprise Financial Inc	10.49K	Novo	$72,570	0.0%	New	1	SEC ↗
56	New York State Common Retirement…	5.20K	+5100.0%	$35,984	0.0%	▲ Add	3	SEC ↗
57	Mirae Asset Global Investments Co.…	2.43K	-13.7%	$16,843	0.0%	▼ Trim	3	SEC ↗
58	Royal Bank Of Canada	1.09K	Novo	$7,000	0.0%	New	1	SEC ↗ ×3
59	Zurcher Kantonalbank (Zurich…	965	+102.3%	$6,678	0.0%	▲ Add	2	SEC ↗
60	Rockefeller Capital Management L.P.	738	0.0%	$5,107	0.0%	Held	2	SEC ↗
61	UBS AM, a distinct business unit of…	588	0.0%	$4,069	0.0%	Held	3	SEC ↗
62	Pnc Financial Services Group, Inc.	387	Novo	$2,678	0.0%	New	1	SEC ↗
63	Us Bancorp \De\	264	-55.2%	$1,827	0.0%	▼ Trim	3	SEC ↗
64	Simplex Trading, Llc	20	Novo	$138	0.0%	New	1	SEC ↗
65	Osaic Holdings, Inc.	19	-95.1%	$131	0.0%	▼ Trim	3	SEC ↗
66	National Bank Of Canada /Fi/	1	Novo	$7	0.0%	New	1	SEC ↗

"Peso do gestor" = a participação da posição no valor total de ações 13F reportado pelo gestor — a medida de convicção. ✦ = gestor curado.

Novos compradores

Norges Bank	$26.08M	0.0%
Hrt Financial Lp	$1.18M	0.0%
Allspring Global Investments…	$298,819	0.0%
Two Sigma Investments	$292,889	0.0%
Sei Investments Co	$138,580	0.0%
Jane Street Group, Llc	$107,910	0.0%
Mercer Global Advisors Inc…	$92,396	0.0%
Canada Pension Plan…	$79,580	0.0%
Wealth Enhancement Advisory…	$75,428	0.0%
Ameriprise Financial Inc	$72,570	0.0%
Royal Bank Of Canada	$7,000	0.0%
Pnc Financial Services Group…	$2,678	0.0%

Encerrado

Federated Hermes, Inc.	$8.82M	era 0.0%
Pictet Asset Management…	$6.60M	era 0.0%
Alyeska Investment Group, L.P.	$2.68M	era 0.0%
Marshall Wace	$600,930	era 0.0%
Tudor Investment Corp Et Al	$237,708	era 0.0%
Victory Capital Management Inc	$232,794	era 0.0%
Susquehanna International…	$143,649	era 0.0%
Franklin Resources Inc	$131,301	era 0.0%
Corient Private Wealth LP	$109,413	era 0.0%
Nomura Asset Management Co Ltd	$0	era 0.0%

Contexto de mercado completo: entre TODOS os filers 13F (dados estruturados da SEC, Q1 2026): 140 detentores, 44.42M ações, $399.81M reportado. Este é um período diferente e mais antigo do que os dados do universo rastreado acima, e os dois nunca são combinados.

Frequentemente detidos em conjunto

O que os detentores rastreados deste título mais frequentemente também detêm — contagens de participação compartilhada, não relações fundamentais.

CBRE66titulares compartilhados CIEN66titulares compartilhados AVGO66titulares compartilhados BSX66titulares compartilhados AMZN66titulares compartilhados

Transações de insiders

Compras no mercado aberto (P)

Nenhuma compra direta no mercado por insiders em nossa janela de cobertura.

Vendas no mercado aberto (S)

Sep 16 Ambrose Allison

Officer · 485 ações · $2,663

Sep 16 Deykin Aaron

Officer · 895 ações · $4,914

Sep 16 GRAY MICHAEL

Officer · 853 ações · $4,683

Sep 16 Houghton Adam

Officer · 700 ações · $3,843

Prêmios, exercícios e retenção fiscal nunca são contabilizados como compras ou vendas aqui. Metodologia

Participação beneficiária

Aug 12 SC 13G/A — NORGES BANK

Ver filing original na SEC ↗

Jul 30 SC 13G — BlackRock, Inc.