证券记录 · 已归档季度

UPB

Upstream Bio, Inc. · Healthcare · Biotechnology

2.99 +6.8% 市值 $163.77M 报价延迟（FMP） · 截至 Oct 22 22:08 UTC · 与下方申报数据相互独立

Q2 2026 Q1 2026 Q4 2025 Q3 2025 Q2 2025 Q1 2025 Q4 2024

64被追踪持有人

+3Δ持有人

24.32M持有股份

$219.33M报告持仓市值

+14新建仓位

−12清仓

Rising 计算方式说明 → 在研究台查询相关说明 →

动量输入（同类管理人）：持有人广度 +4.9% · 股份流向 +0.9% · 净新建仓位 +3.1% · 公式
广泛增持：持股数量上升，持有人数量增加

所有持股数据：仅限已追踪的 13F 管理人，普通股持仓，报告期 Q1 2026

持股变化趋势

季度	持有人	Δ	股份	报告持仓市值	新增	清仓
Q2 2026	66	+3	29.87M	$206.85M	+14	−10
Q1 2026	64	+3	24.32M	$219.33M	+14	−12
Q4 2025	62	+3	27.51M	$746.80M	+4	n/a
Q3 2025	14	+2	17.53M	$329.70M	+2	−1
Q2 2025	10	-1	15.87M	$174.20M	+1	−2
Q1 2025	8	+1	3.40M	$20.78M	+3	−2
Q4 2024	7	+6	3.71M	$60.61M	+6	n/a

持有人数量

持有人 · Q1 2026

#	管理人	股份	Δ股份	价值	其权重		持有
1	Fidelity (FMR) ✦	8.10M	+7.8%	$72.91M	0.0%	▲ Add	4	SEC ↗ ×4
2	BlackRock ✦ (被动)	3.37M	+0.8%	$30.34M	0.0%	▲ Add	4	SEC ↗ ×13
3	Vanguard Capital Management Llc	1.87M	n/a	$16.86M	0.0%	n/c	1	SEC ↗
4	Federated Hermes, Inc.	979.76K	+203169.3%	$8.82M	0.0%	▲ Add	2	SEC ↗
5	Geode Capital Management ✦ (被动)	950.62K	+11.6%	$8.56M	0.0%	▲ Add	6	SEC ↗ ×2
6	Millennium Management ✦	937.32K	+81.2%	$8.44M	0.0%	▲ Add	3	SEC ↗
7	D. E. Shaw & Co. ✦	820.48K	+2928.6%	$7.38M	0.0%	▲ Add	2	SEC ↗ ×2
8	Pictet Asset Management Holding SA	733.43K	-5.1%	$6.60M	0.0%	▼ Trim	2	SEC ↗
9	State Street Global Advisors ✦ (被动)	705.35K	-46.5%	$6.35M	0.0%	▼ Trim	6	SEC ↗
10	Hsbc Holdings Plc	640.33K	新增	$5.76M	0.0%	New	1	SEC ↗
11	Qube Research & Technologies Ltd	619.32K	新增	$5.57M	0.0%	New	1	SEC ↗
12	Morgan Stanley ✦	552.61K	+352.7%	$4.97M	0.0%	▲ Add	3	SEC ↗ ×6
13	JPMorgan Chase ✦	463.00K	+319.8%	$4.07M	0.0%	▲ Add	3	SEC ↗ ×4
14	Wellington Management ✦	342.35K	-61.7%	$3.08M	0.0%	▼ Trim	6	SEC ↗
15	Goldman Sachs Group ✦	316.59K	-5.1%	$2.85M	0.0%	▼ Trim	3	SEC ↗
16	Alyeska Investment Group, L.P.	298.33K	0.0%	$2.68M	0.0%	Held	2	SEC ↗
17	Northern Trust Corp	260.99K	+10.2%	$2.35M	0.0%	▲ Add	2	SEC ↗ ×5
18	Charles Schwab Investment…	257.73K	-9.6%	$2.32M	0.0%	▼ Trim	2	SEC ↗
19	UBS Group AG	231.25K	-87.2%	$2.08M	0.0%	▼ Trim	2	SEC ↗ ×2
20	Arrowstreet Capital ✦	185.09K	新增	$1.67M	0.0%	New	1	SEC ↗
21	Deutsche Bank Ag\	180.89K	+41.5%	$1.63M	0.0%	▲ Add	2	SEC ↗ ×2
22	Point72 Asset Management ✦	178.17K	新增	$1.60M	0.0%	New	1	SEC ↗
23	Bnp Paribas Financial Markets	126.00K	+2432.2%	$1.13M	0.0%	▲ Add	2	SEC ↗
24	Alliancebernstein L.P.	31.01K	0.0%	$841,922	0.0%	Held	2	SEC ↗
25	American Century Companies Inc	87.62K	-0.1%	$788,616	0.0%	▼ Trim	2	SEC ↗
26	Bank of New York Mellon Corp	81.38K	-4.1%	$732,447	0.0%	▼ Trim	2	SEC ↗ ×3
27	Dimensional Fund Advisors Lp	80.00K	新增	$719,492	0.0%	New	1	SEC ↗ ×3
28	Nuveen, LLC	75.54K	-3.9%	$679,824	0.0%	▼ Trim	2	SEC ↗ ×2
29	AQR Capital Management ✦	72.17K	+136.6%	$649,539	0.0%	▲ Add	5	SEC ↗ ×5
30	Marshall Wace ✦	66.77K	-80.6%	$600,930	0.0%	▼ Trim	6	SEC ↗ ×2
31	Renaissance Technologies ✦	62.10K	+278.7%	$558,900	0.0%	▲ Add	2	SEC ↗
32	Quantinno Capital Management LP	49.39K	+220.4%	$444,501	0.0%	▲ Add	2	SEC ↗
33	Bank Of America Corp /De/	48.46K	-43.9%	$436,140	0.0%	▼ Trim	2	SEC ↗
34	Swiss National Bank	48.10K	+80.8%	$432,900	0.0%	▲ Add	2	SEC ↗
35	Squarepoint Ops LLC	44.63K	新增	$401,634	0.0%	New	1	SEC ↗
36	State Of Wisconsin Investment Board	41.67K	新增	$375,039	0.0%	New	1	SEC ↗
37	Rhumbline Advisers	41.20K	-0.8%	$370,827	0.0%	▼ Trim	2	SEC ↗
38	Invesco Ltd.	40.51K	-75.2%	$364,590	0.0%	▼ Trim	2	SEC ↗ ×4
39	California State Teachers…	39.66K	+170.7%	$356,949	0.0%	▲ Add	2	SEC ↗
40	Mariner, LLC	27.31K	+130.9%	$245,834	0.0%	▲ Add	2	SEC ↗
41	T. Rowe Price ✦	26.43K	+34.6%	$238,000	0.0%	▲ Add	4	SEC ↗
42	Tudor Investment Corp Et Al	26.41K	新增	$237,708	0.0%	New	1	SEC ↗
43	Victory Capital Management Inc	25.87K	新增	$232,794	0.0%	New	1	SEC ↗
44	Barclays Plc	24.72K	-95.3%	$222,480	0.0%	▼ Trim	2	SEC ↗ ×2
45	Man Group plc	21.15K	新增	$190,386	0.0%	New	1	SEC ↗
46	Wells Fargo & Company/Mn	18.40K	-50.0%	$165,618	0.0%	▼ Trim	2	SEC ↗ ×2
47	Susquehanna International Group, Llp	15.96K	-71.4%	$143,649	0.0%	▼ Trim	2	SEC ↗
48	MIRAE ASSET GLOBAL ETFS HOLDINGS…	15.61K	-10.8%	$140,472	0.0%	▼ Trim	2	SEC ↗
49	Manufacturers Life Insurance…	15.34K	+51.2%	$138,042	0.0%	▲ Add	2	SEC ↗
50	Franklin Resources Inc	14.59K	新增	$131,301	0.0%	New	1	SEC ↗ ×2
51	Corient Private Wealth LP	12.16K	新增	$109,413	0.0%	New	1	SEC ↗
52	Creative Planning	10.85K	-7.7%	$97,650	0.0%	▼ Trim	2	SEC ↗
53	Legal & General Group Plc	9.61K	-29.9%	$86,481	0.0%	▼ Trim	2	SEC ↗ ×3
54	Citigroup Inc	5.05K	-27.3%	$45,495	0.0%	▼ Trim	2	SEC ↗ ×2
55	Cwm, Llc	3.88K	+15.6%	$34,947	0.0%	▲ Add	2	SEC ↗
56	Russell Investments Group, Ltd.	3.65K	+29.2%	$32,823	0.0%	▲ Add	2	SEC ↗ ×2
57	Mirae Asset Global Investments Co.…	2.82K	+7.3%	$25,371	0.0%	▲ Add	2	SEC ↗
58	Rockefeller Capital Management L.P.	738	新增	$6,642	0.0%	New	1	SEC ↗
59	Us Bancorp \De\	590	+8.1%	$5,310	0.0%	▲ Add	2	SEC ↗
60	UBS AM, a distinct business unit of…	588	+143.0%	$5,292	0.0%	▲ Add	2	SEC ↗
61	Zurcher Kantonalbank (Zurich…	477	新增	$4,293	0.0%	New	1	SEC ↗
62	Osaic Holdings, Inc.	389	+7680.0%	$3,501	0.0%	▲ Add	2	SEC ↗
63	New York State Common Retirement…	100	-99.2%	$900	0.0%	▼ Trim	2	SEC ↗
64	Nomura Asset Management Co Ltd	0	n/a	$0	0.0%	Held	2	SEC ↗

"持仓权重"指该仓位占该管理人13F申报股票组合市值的比例，即持仓信心指标。✦ = 精选管理人。

新增买入方

Hsbc Holdings Plc	$5.76M	0.0%
Qube Research & Technologies…	$5.57M	0.0%
Arrowstreet Capital	$1.67M	0.0%
Point72 Asset Management	$1.60M	0.0%
Dimensional Fund Advisors Lp	$719,492	0.0%
Squarepoint Ops LLC	$401,634	0.0%
State Of Wisconsin Investment…	$375,039	0.0%
Tudor Investment Corp Et Al	$237,708	0.0%
Victory Capital Management Inc	$232,794	0.0%
Man Group plc	$190,386	0.0%
Franklin Resources Inc	$131,301	0.0%
Corient Private Wealth LP	$109,413	0.0%

已清仓

Norges Bank	$78.26M	曾为 0.0%
Janus Henderson Group Plc	$41.42M	曾为 0.0%
Jennison Associates Llc	$7.84M	曾为 0.0%
Ameriprise Financial Inc	$1.54M	曾为 0.0%
Citadel Advisors	$364,353	曾为 0.0%
Two Sigma Investments	$285,075	曾为 0.0%
ProShare Advisors LLC	$226,811	曾为 0.0%
Sei Investments Co	$219,562	曾为 0.0%
Royal Bank Of Canada	$26,000	曾为 0.0%
Simplex Trading, Llc	$12,651	曾为 0.0%
Daiwa Securities Group Inc.	$5,000	曾为 0.0%
Pnc Financial Services Group…	$2,877	曾为 0.0%