Registro do valor mobiliário · trimestre arquivado

UPB

Upstream Bio, Inc. · Healthcare · Biotechnology

2.76 -18.1% cap. de mercado $151.17M cotação com atraso (FMP) · em Oct 18 03:59 UTC · independente dos dados de arquivo abaixo

Q2 2026 Q1 2026 Q4 2025 Q3 2025 Q2 2025 Q1 2025 Q4 2024

64Detentores rastreados

+3Δ titulares

24.32MAções mantidas

$219.33MValor reportado

+14Novas posições

−12Saídas

Rising Como estes valores são calculados → Explicar isso no Research Desk →

Dados de momentum (gestores comparáveis): amplitude de detentores +4.9% · fluxo de ações +0.9% · novas posições líquidas +3.1% · fórmula
Acumulação ampla: ações crescentes entre mais detentores

Todos os dados de participação: apenas gestores 13F rastreados, posições em ações ordinárias, período de referência Q1 2026

Participação ao longo do tempo

Trimestre	Detentores	Δ	Ações	Valor reportado	Novo	Saídas
Q2 2026	66	+3	29.87M	$206.85M	+14	−10
Q1 2026	64	+3	24.32M	$219.33M	+14	−12
Q4 2025	62	+3	27.51M	$746.80M	+4	n/a
Q3 2025	14	+2	17.53M	$329.70M	+2	−1
Q2 2025	10	-1	15.87M	$174.20M	+1	−2
Q1 2025	8	+1	3.40M	$20.78M	+3	−2
Q4 2024	7	+6	3.71M	$60.61M	+6	n/a

Número de detentores

Quem detém · Q1 2026

#	Gestor	Ações	Δ ações	Valor	Seu peso		Detido
1	Fidelity (FMR) ✦	8.10M	+7.8%	$72.91M	0.0%	▲ Add	4	SEC ↗ ×4
2	BlackRock ✦ (passivo)	3.37M	+0.8%	$30.34M	0.0%	▲ Add	4	SEC ↗ ×13
3	Vanguard Capital Management Llc	1.87M	n/a	$16.86M	0.0%	n/c	1	SEC ↗
4	Federated Hermes, Inc.	979.76K	+203169.3%	$8.82M	0.0%	▲ Add	2	SEC ↗
5	Geode Capital Management ✦ (passivo)	950.62K	+11.6%	$8.56M	0.0%	▲ Add	6	SEC ↗ ×2
6	Millennium Management ✦	937.32K	+81.2%	$8.44M	0.0%	▲ Add	3	SEC ↗
7	D. E. Shaw & Co. ✦	820.48K	+2928.6%	$7.38M	0.0%	▲ Add	2	SEC ↗ ×2
8	Pictet Asset Management Holding SA	733.43K	-5.1%	$6.60M	0.0%	▼ Trim	2	SEC ↗
9	State Street Global Advisors ✦ (passivo)	705.35K	-46.5%	$6.35M	0.0%	▼ Trim	6	SEC ↗
10	Hsbc Holdings Plc	640.33K	Novo	$5.76M	0.0%	New	1	SEC ↗
11	Qube Research & Technologies Ltd	619.32K	Novo	$5.57M	0.0%	New	1	SEC ↗
12	Morgan Stanley ✦	552.61K	+352.7%	$4.97M	0.0%	▲ Add	3	SEC ↗ ×6
13	JPMorgan Chase ✦	463.00K	+319.8%	$4.07M	0.0%	▲ Add	3	SEC ↗ ×4
14	Wellington Management ✦	342.35K	-61.7%	$3.08M	0.0%	▼ Trim	6	SEC ↗
15	Goldman Sachs Group ✦	316.59K	-5.1%	$2.85M	0.0%	▼ Trim	3	SEC ↗
16	Alyeska Investment Group, L.P.	298.33K	0.0%	$2.68M	0.0%	Held	2	SEC ↗
17	Northern Trust Corp	260.99K	+10.2%	$2.35M	0.0%	▲ Add	2	SEC ↗ ×5
18	Charles Schwab Investment…	257.73K	-9.6%	$2.32M	0.0%	▼ Trim	2	SEC ↗
19	UBS Group AG	231.25K	-87.2%	$2.08M	0.0%	▼ Trim	2	SEC ↗ ×2
20	Arrowstreet Capital ✦	185.09K	Novo	$1.67M	0.0%	New	1	SEC ↗
21	Deutsche Bank Ag\	180.89K	+41.5%	$1.63M	0.0%	▲ Add	2	SEC ↗ ×2
22	Point72 Asset Management ✦	178.17K	Novo	$1.60M	0.0%	New	1	SEC ↗
23	Bnp Paribas Financial Markets	126.00K	+2432.2%	$1.13M	0.0%	▲ Add	2	SEC ↗
24	Alliancebernstein L.P.	31.01K	0.0%	$841,922	0.0%	Held	2	SEC ↗
25	American Century Companies Inc	87.62K	-0.1%	$788,616	0.0%	▼ Trim	2	SEC ↗
26	Bank of New York Mellon Corp	81.38K	-4.1%	$732,447	0.0%	▼ Trim	2	SEC ↗ ×3
27	Dimensional Fund Advisors Lp	80.00K	Novo	$719,492	0.0%	New	1	SEC ↗ ×3
28	Nuveen, LLC	75.54K	-3.9%	$679,824	0.0%	▼ Trim	2	SEC ↗ ×2
29	AQR Capital Management ✦	72.17K	+136.6%	$649,539	0.0%	▲ Add	5	SEC ↗ ×5
30	Marshall Wace ✦	66.77K	-80.6%	$600,930	0.0%	▼ Trim	6	SEC ↗ ×2
31	Renaissance Technologies ✦	62.10K	+278.7%	$558,900	0.0%	▲ Add	2	SEC ↗
32	Quantinno Capital Management LP	49.39K	+220.4%	$444,501	0.0%	▲ Add	2	SEC ↗
33	Bank Of America Corp /De/	48.46K	-43.9%	$436,140	0.0%	▼ Trim	2	SEC ↗
34	Swiss National Bank	48.10K	+80.8%	$432,900	0.0%	▲ Add	2	SEC ↗
35	Squarepoint Ops LLC	44.63K	Novo	$401,634	0.0%	New	1	SEC ↗
36	State Of Wisconsin Investment Board	41.67K	Novo	$375,039	0.0%	New	1	SEC ↗
37	Rhumbline Advisers	41.20K	-0.8%	$370,827	0.0%	▼ Trim	2	SEC ↗
38	Invesco Ltd.	40.51K	-75.2%	$364,590	0.0%	▼ Trim	2	SEC ↗ ×4
39	California State Teachers…	39.66K	+170.7%	$356,949	0.0%	▲ Add	2	SEC ↗
40	Mariner, LLC	27.31K	+130.9%	$245,834	0.0%	▲ Add	2	SEC ↗
41	T. Rowe Price ✦	26.43K	+34.6%	$238,000	0.0%	▲ Add	4	SEC ↗
42	Tudor Investment Corp Et Al	26.41K	Novo	$237,708	0.0%	New	1	SEC ↗
43	Victory Capital Management Inc	25.87K	Novo	$232,794	0.0%	New	1	SEC ↗
44	Barclays Plc	24.72K	-95.3%	$222,480	0.0%	▼ Trim	2	SEC ↗ ×2
45	Man Group plc	21.15K	Novo	$190,386	0.0%	New	1	SEC ↗
46	Wells Fargo & Company/Mn	18.40K	-50.0%	$165,618	0.0%	▼ Trim	2	SEC ↗ ×2
47	Susquehanna International Group, Llp	15.96K	-71.4%	$143,649	0.0%	▼ Trim	2	SEC ↗
48	MIRAE ASSET GLOBAL ETFS HOLDINGS…	15.61K	-10.8%	$140,472	0.0%	▼ Trim	2	SEC ↗
49	Manufacturers Life Insurance…	15.34K	+51.2%	$138,042	0.0%	▲ Add	2	SEC ↗
50	Franklin Resources Inc	14.59K	Novo	$131,301	0.0%	New	1	SEC ↗ ×2
51	Corient Private Wealth LP	12.16K	Novo	$109,413	0.0%	New	1	SEC ↗
52	Creative Planning	10.85K	-7.7%	$97,650	0.0%	▼ Trim	2	SEC ↗
53	Legal & General Group Plc	9.61K	-29.9%	$86,481	0.0%	▼ Trim	2	SEC ↗ ×3
54	Citigroup Inc	5.05K	-27.3%	$45,495	0.0%	▼ Trim	2	SEC ↗ ×2
55	Cwm, Llc	3.88K	+15.6%	$34,947	0.0%	▲ Add	2	SEC ↗
56	Russell Investments Group, Ltd.	3.65K	+29.2%	$32,823	0.0%	▲ Add	2	SEC ↗ ×2
57	Mirae Asset Global Investments Co.…	2.82K	+7.3%	$25,371	0.0%	▲ Add	2	SEC ↗
58	Rockefeller Capital Management L.P.	738	Novo	$6,642	0.0%	New	1	SEC ↗
59	Us Bancorp \De\	590	+8.1%	$5,310	0.0%	▲ Add	2	SEC ↗
60	UBS AM, a distinct business unit of…	588	+143.0%	$5,292	0.0%	▲ Add	2	SEC ↗
61	Zurcher Kantonalbank (Zurich…	477	Novo	$4,293	0.0%	New	1	SEC ↗
62	Osaic Holdings, Inc.	389	+7680.0%	$3,501	0.0%	▲ Add	2	SEC ↗
63	New York State Common Retirement…	100	-99.2%	$900	0.0%	▼ Trim	2	SEC ↗
64	Nomura Asset Management Co Ltd	0	n/a	$0	0.0%	Held	2	SEC ↗

"Peso no portfolio" = a participação da posição no valor de renda variável 13F reportado pelo gestor: a medida de convicção. ✦ = gestor curado.

Novos compradores

Hsbc Holdings Plc	$5.76M	0.0%
Qube Research & Technologies…	$5.57M	0.0%
Arrowstreet Capital	$1.67M	0.0%
Point72 Asset Management	$1.60M	0.0%
Dimensional Fund Advisors Lp	$719,492	0.0%
Squarepoint Ops LLC	$401,634	0.0%
State Of Wisconsin Investment…	$375,039	0.0%
Tudor Investment Corp Et Al	$237,708	0.0%
Victory Capital Management Inc	$232,794	0.0%
Man Group plc	$190,386	0.0%
Franklin Resources Inc	$131,301	0.0%
Corient Private Wealth LP	$109,413	0.0%

Encerrado

Norges Bank	$78.26M	era 0.0%
Janus Henderson Group Plc	$41.42M	era 0.0%
Jennison Associates Llc	$7.84M	era 0.0%
Ameriprise Financial Inc	$1.54M	era 0.0%
Citadel Advisors	$364,353	era 0.0%
Two Sigma Investments	$285,075	era 0.0%
ProShare Advisors LLC	$226,811	era 0.0%
Sei Investments Co	$219,562	era 0.0%
Royal Bank Of Canada	$26,000	era 0.0%
Simplex Trading, Llc	$12,651	era 0.0%
Daiwa Securities Group Inc.	$5,000	era 0.0%
Pnc Financial Services Group…	$2,877	era 0.0%

Contexto de mercado completo: entre TODOS os filers 13F (dados estruturados da SEC, Q1 2026): 140 detentores, 44.42M ações, $399.81M reportado. Este é um período diferente e mais antigo do que os dados do universo rastreado acima, e os dois nunca são combinados.

Frequentemente detidos em conjunto

O que os detentores rastreados deste título mais frequentemente também detêm: contagens de propriedade compartilhada, não relações fundamentais.

IEX64titulares compartilhados AFL64titulares compartilhados TMO64titulares compartilhados NVDA64titulares compartilhados CGNX64titulares compartilhados

Transações de insiders

Compras no mercado aberto (P)

Nenhuma compra direta no mercado por insiders em nossa janela de cobertura.

Vendas no mercado aberto (S)

Sep 16 Ambrose Allison

Officer · 485 ações · $2,663

Sep 16 Deykin Aaron

Officer · 895 ações · $4,914

Sep 16 GRAY MICHAEL

Officer · 853 ações · $4,683

Sep 16 Houghton Adam

Officer · 700 ações · $3,843

Prêmios, exercícios e retenção fiscal nunca são contabilizados como compras ou vendas aqui. Metodologia

Participação beneficiária

Aug 12 SC 13G/A: NORGES BANK

Ver filing original na SEC ↗

Jul 30 SC 13G: BlackRock, Inc.