Ficha del valor · trimestre archivado
UPB
Upstream Bio, Inc. · Healthcare · Biotechnology
62Tenedores rastreados
+3Δ titulares
27.51MAcciones mantenidas
$746.80MValor declarado
+4Nuevas posiciones
−0Cierres
Señales de momentum (gestores comparables):
amplitud de titulares +5.1% ·
flujo de acciones +1.2% ·
nuevas posiciones netas +6.5%
· fórmula
Acumulación amplia: acciones en aumento entre más titulares
Todas las cifras de propiedad: únicamente gestores 13F seguidos, posiciones en acciones ordinarias, período de referencia Q4 2025
Participación a lo largo del tiempo
| Trimestre | Titulares | Δ | Acciones | Valor declarado | Nuevo | Cierres |
|---|---|---|---|---|---|---|
| Q2 2026 | 66 | +3 | 29.87M | $206.85M | +14 | −10 |
| Q1 2026 | 64 | +3 | 24.32M | $219.33M | +14 | −12 |
| Q4 2025 | 62 | +3 | 27.51M | $746.80M | +4 | n/a |
| Q3 2025 | 14 | +2 | 17.53M | $329.70M | +2 | −1 |
| Q2 2025 | 10 | -1 | 15.87M | $174.20M | +1 | −2 |
| Q1 2025 | 8 | +1 | 3.40M | $20.78M | +3 | −2 |
| Q4 2024 | 7 | +6 | 3.71M | $60.61M | +6 | n/a |
Quién lo tiene en cartera · Q4 2025
| # | Gestor | Acciones | Δ acciones | Valor | Su ponderación | Mantenida | ||
|---|---|---|---|---|---|---|---|---|
| 1 | Fidelity (FMR) ✦ | 7.52M | -7.0% | $204.12M | 0.0% | ▼ Trim | 3 | SEC ↗ ×5 |
| 2 | BlackRock ✦ (pasivo) | 3.34M | +28.4% | $90.80M | 0.0% | ▲ Add | 3 | SEC ↗ ×10 |
| 3 | Norges Bank ✦ (pasivo) | 2.88M | Nuevo | $78.26M | 0.0% | New | 1 | SEC ↗ |
| 4 | The Vanguard Group ✦ (pasivo) | 2.39M | -2.2% | $64.85M | 0.0% | ▼ Trim | 3 | SEC ↗ ×5 |
| 5 | UBS Group AG | 1.81M | n/a | $49.04M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 6 | Janus Henderson Group Plc | 1.53M | n/a | $41.42M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 7 | State Street Global Advisors ✦ (pasivo) | 1.32M | +18.4% | $35.82M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 8 | Wellington Management ✦ | 894.73K | -20.5% | $24.29M | 0.0% | ▼ Trim | 5 | SEC ↗ |
| 9 | Geode Capital Management ✦ (pasivo) | 851.91K | +4.3% | $23.13M | 0.0% | ▲ Add | 5 | SEC ↗ ×2 |
| 10 | Pictet Asset Management Holding SA | 773.15K | n/a | $20.99M | 0.0% | n/c | 1 | SEC ↗ |
| 11 | Barclays Plc | 524.50K | n/a | $14.24M | 0.0% | n/c | 1 | SEC ↗ |
| 12 | Millennium Management ✦ | 517.26K | +1189.5% | $14.04M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 13 | Marshall Wace ✦ | 343.79K | -60.4% | $9.33M | 0.0% | ▼ Trim | 5 | SEC ↗ |
| 14 | Goldman Sachs Group ✦ | 333.48K | +49.4% | $9.05M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 15 | Alyeska Investment Group, L.P. | 298.33K | n/a | $8.10M | 0.0% | n/c | 1 | SEC ↗ |
| 16 | Jennison Associates Llc | 288.85K | n/a | $7.84M | 0.0% | n/c | 1 | SEC ↗ |
| 17 | Charles Schwab Investment… | 284.93K | n/a | $7.74M | 0.0% | n/c | 1 | SEC ↗ |
| 18 | Northern Trust Corp | 236.80K | n/a | $6.43M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 19 | Invesco Ltd. | 163.19K | n/a | $4.43M | 0.0% | n/c | 1 | SEC ↗ ×4 |
| 20 | Deutsche Bank Ag\ | 127.81K | n/a | $3.47M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 21 | Morgan Stanley ✦ | 122.07K | +39.5% | $3.31M | 0.0% | ▲ Add | 2 | SEC ↗ ×5 |
| 22 | JPMorgan Chase ✦ | 110.28K | +84.1% | $2.99M | 0.0% | ▲ Add | 2 | SEC ↗ ×3 |
| 23 | American Century Companies Inc | 87.76K | n/a | $2.38M | 0.0% | n/c | 1 | SEC ↗ |
| 24 | Bank Of America Corp /De/ | 86.38K | n/a | $2.35M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 25 | Bank of New York Mellon Corp | 84.85K | n/a | $2.30M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 26 | Nuveen, LLC | 78.57K | n/a | $2.13M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 27 | Ameriprise Financial Inc | 56.56K | n/a | $1.54M | 0.0% | n/c | 1 | SEC ↗ |
| 28 | Susquehanna International Group, Llp | 55.84K | n/a | $1.52M | 0.0% | n/c | 1 | SEC ↗ |
| 29 | Rhumbline Advisers | 41.52K | n/a | $1.13M | 0.0% | n/c | 1 | SEC ↗ |
| 30 | Wells Fargo & Company/Mn | 36.79K | n/a | $998,957 | 0.0% | n/c | 1 | SEC ↗ |
| 31 | Alliancebernstein L.P. | 31.01K | n/a | $841,922 | 0.0% | n/c | 1 | SEC ↗ |
| 32 | AQR Capital Management ✦ | 30.50K | +1.8% | $828,158 | 0.0% | ▲ Add | 4 | SEC ↗ ×6 |
| 33 | D. E. Shaw & Co. ✦ | 27.09K | Nuevo | $735,521 | 0.0% | New | 1 | SEC ↗ |
| 34 | Swiss National Bank | 26.60K | n/a | $722,190 | 0.0% | n/c | 1 | SEC ↗ |
| 35 | T. Rowe Price ✦ | 19.64K | +6.1% | $534,000 | 0.0% | ▲ Add | 3 | SEC ↗ |
| 36 | MIRAE ASSET GLOBAL ETFS HOLDINGS… | 17.49K | n/a | $475,264 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 37 | Renaissance Technologies ✦ | 16.40K | Nuevo | $445,260 | 0.0% | New | 1 | SEC ↗ |
| 38 | Quantinno Capital Management LP | 15.41K | n/a | $418,517 | 0.0% | n/c | 1 | SEC ↗ |
| 39 | California State Teachers… | 14.65K | n/a | $397,802 | 0.0% | n/c | 1 | SEC ↗ |
| 40 | Legal & General Group Plc | 13.71K | n/a | $372,199 | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 41 | Citadel Advisors ✦ | 13.42K | Nuevo | $364,353 | 0.0% | New | 1 | SEC ↗ |
| 42 | Mariner, LLC | 11.83K | n/a | $321,174 | 0.0% | n/c | 1 | SEC ↗ |
| 43 | Creative Planning | 11.75K | n/a | $318,985 | 0.0% | n/c | 1 | SEC ↗ |
| 44 | New York State Common Retirement… | 11.70K | n/a | $317,655 | 0.0% | n/c | 1 | SEC ↗ |
| 45 | Two Sigma Investments ✦ | 10.50K | 0.0% | $285,075 | 0.0% | Held | 2 | SEC ↗ |
| 46 | Manufacturers Life Insurance… | 10.15K | n/a | $275,491 | 0.0% | n/c | 1 | SEC ↗ |
| 47 | ProShare Advisors LLC | 8.35K | n/a | $226,811 | 0.0% | n/c | 1 | SEC ↗ |
| 48 | Sei Investments Co | 8.09K | n/a | $219,562 | 0.0% | n/c | 1 | SEC ↗ |
| 49 | Citigroup Inc | 6.95K | n/a | $188,665 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 50 | Bnp Paribas Financial Markets | 4.98K | n/a | $135,098 | 0.0% | n/c | 1 | SEC ↗ |
| 51 | Cwm, Llc | 3.36K | n/a | $91,000 | 0.0% | n/c | 1 | SEC ↗ |
| 52 | Russell Investments Group, Ltd. | 2.82K | n/a | $76,644 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 53 | Mirae Asset Global Investments Co.… | 2.63K | n/a | $71,296 | 0.0% | n/c | 1 | SEC ↗ |
| 54 | Royal Bank Of Canada | 969 | n/a | $26,000 | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 55 | Us Bancorp \De\ | 546 | n/a | $14,824 | 0.0% | n/c | 1 | SEC ↗ |
| 56 | Federated Hermes, Inc. | 482 | n/a | $13,086 | 0.0% | n/c | 1 | SEC ↗ |
| 57 | Simplex Trading, Llc | 466 | n/a | $12,651 | 0.0% | n/c | 1 | SEC ↗ |
| 58 | UBS AM, a distinct business unit of… | 242 | n/a | $6,570 | 0.0% | n/c | 1 | SEC ↗ |
| 59 | Daiwa Securities Group Inc. | 180 | n/a | $5,000 | 0.0% | n/c | 1 | SEC ↗ |
| 60 | Pnc Financial Services Group, Inc. | 106 | n/a | $2,877 | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 61 | Osaic Holdings, Inc. | 5 | n/a | $136 | 0.0% | n/c | 1 | SEC ↗ |
| 62 | Nomura Asset Management Co Ltd | 0 | n/a | $0 | 0.0% | n/c | 1 | SEC ↗ |
"Their weight" = la participación de la posición en el valor de renta variable 13F reportado por ese manager: la medida de convicción. ✦ = manager curado.
Nuevos compradores
| Norges Bank | $78.26M | 0.0% |
| D. E. Shaw & Co. | $735,521 | 0.0% |
| Renaissance Technologies | $445,260 | 0.0% |
| Citadel Advisors | $364,353 | 0.0% |
Posición cerrada
| Sin salidas rastreadas este trimestre. |
Contexto de mercado completo: entre TODOS los filers 13F (datos estructurados SEC, Q1 2026): 140 tenedores, 44.42M acciones, $399.81M declarado. Este es un período diferente y anterior al de las cifras del universo rastreado que figuran arriba, y ambos nunca se mezclan.
Frecuentemente cotituladas
Qué más suelen tener los titulares rastreados de este valor: recuentos de titularidad compartida, no relaciones fundamentales.
Compras en mercado abierto (P)
Sin compras en mercado abierto por parte de insiders en nuestra ventana de cobertura.
Ventas en mercado abierto (S)
Sep 16
Ambrose Allison
Officer · 485 acc. · $2,663
Sep 16
Deykin Aaron
Officer · 895 acc. · $4,914
Sep 16
GRAY MICHAEL
Officer · 853 acc. · $4,683
Sep 16
Houghton Adam
Officer · 700 acc. · $3,843
Las adjudicaciones, ejercicios y retenciones fiscales nunca se contabilizan aquí como compras o ventas. Metodología
Aug 12
SC 13G/A: NORGES BANK
Jul 30
SC 13G: BlackRock, Inc.
Procedencia: Participación a partir de posiciones en acciones ordinarias de 13F procesadas (universo rastreado, conjuntos comparables para cambios); filas de iniciados de los Formularios 3/4/5; participaciones de los Schedules 13D/13G; cada filing enlaza con su original en SEC EDGAR.
Período de reporte: Q4 2025 ·
Metodología ·
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