TWST
Twist Bioscience Corporation · Healthcare · Medical - Diagnostics & Research
Momentum inputs (comparable managers):
holder breadth -2.1% ·
share flow -3.7% ·
net new positions -2.2%
— formula
Broad distribution — falling shares and fewer holders
All ownership figures: tracked 13F managers only, common-stock positions, reporting period Q4 2025
| Quarter | Holders | Δ | Shares | Reported value | New | Exits |
|---|---|---|---|---|---|---|
| Q2 2026 | 113 | +8 | 54.73M | $5.62B | +14 | −6 |
| Q1 2026 | 108 | +15 | 51.20M | $2.43B | +20 | −5 |
| Q4 2025 | 92 | -2 | 51.46M | $1.63B | +1 | −3 |
| Q3 2025 | 18 | 0 | 32.97M | $927.70M | +1 | −2 |
| Q2 2025 | 16 | -3 | 28.73M | $1.06B | — | −3 |
| Q1 2025 | 16 | +1 | 15.75M | $618.44M | +2 | −1 |
| Q4 2024 | 15 | 0 | 15.20M | $706.21M | — | — |
| Q3 2024 | 14 | +1 | 11.38M | $514.14M | +2 | −1 |
| Q2 2024 | 13 | — | 12.61M | $621.59M | — | — |
| # | Manager | Shares | Δ shares | Value | Their weight | Held | ||
|---|---|---|---|---|---|---|---|---|
| 1 | ARK Investment Management ✦ | 7.56M | +12.4% | $239.79M | 1.6% | ▲ Add | 7 | SEC ↗ |
| 2 | BlackRock ✦ (passive) | 5.89M | -4.6% | $186.99M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 3 | BlackRock ✦ (passive) | 5.89M | -4.6% | $186.99M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 4 | BlackRock ✦ (passive) | 5.89M | -4.6% | $186.99M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 5 | BlackRock ✦ (passive) | 5.89M | -4.6% | $186.99M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 6 | BlackRock ✦ (passive) | 5.89M | -4.6% | $186.99M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 7 | BlackRock ✦ (passive) | 5.89M | -4.6% | $186.99M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 8 | BlackRock ✦ (passive) | 5.89M | -4.6% | $186.99M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 9 | BlackRock ✦ (passive) | 5.89M | -4.6% | $186.99M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 10 | BlackRock ✦ (passive) | 5.89M | -4.6% | $186.99M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 11 | BlackRock ✦ (passive) | 5.89M | -4.6% | $186.99M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 12 | BlackRock ✦ (passive) | 5.89M | -4.6% | $186.99M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 13 | BlackRock ✦ (passive) | 5.89M | -4.6% | $186.99M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 14 | BlackRock ✦ (passive) | 5.89M | -4.6% | $186.99M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 15 | BlackRock ✦ (passive) | 5.89M | -4.6% | $186.99M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 16 | Artisan Partners Limited Partnership | 5.83M | — | $184.93M | 0.3% | n/c | 1 | SEC ↗ |
| 17 | The Vanguard Group ✦ (passive) | 5.78M | +0.1% | $183.22M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 18 | The Vanguard Group ✦ (passive) | 5.78M | +0.1% | $183.22M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 19 | The Vanguard Group ✦ (passive) | 5.78M | +0.1% | $183.22M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 20 | The Vanguard Group ✦ (passive) | 5.78M | +0.1% | $183.22M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 21 | The Vanguard Group ✦ (passive) | 5.78M | +0.1% | $183.22M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 22 | State Street Global Advisors ✦ (passive) | 3.63M | +17.4% | $115.07M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 23 | Sumitomo Mitsui Trust Group, Inc. | 1.90M | — | $60.36M | 0.0% | n/c | 1 | SEC ↗ |
| 24 | Goldman Sachs Group ✦ | 1.70M | +4.3% | $53.82M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 25 | Goldman Sachs Group ✦ | 1.70M | +4.3% | $53.82M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 26 | Goldman Sachs Group ✦ | 1.70M | +4.3% | $53.82M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 27 | Millennium Management ✦ | 1.50M | -16.5% | $47.51M | 0.0% | ▼ Trim | 7 | SEC ↗ |
| 28 | Geode Capital Management ✦ (passive) | 1.46M | +0.8% | $46.30M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 29 | Geode Capital Management ✦ (passive) | 1.46M | +0.8% | $46.30M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 30 | Invesco Ltd. | 1.29M | — | $40.93M | 0.0% | n/c | 1 | SEC ↗ |
| 31 | Invesco Ltd. | 1.29M | — | $40.93M | 0.0% | n/c | 1 | SEC ↗ |
| 32 | Invesco Ltd. | 1.29M | — | $40.93M | 0.0% | n/c | 1 | SEC ↗ |
| 33 | Invesco Ltd. | 1.29M | — | $40.93M | 0.0% | n/c | 1 | SEC ↗ |
| 34 | Invesco Ltd. | 1.29M | — | $40.93M | 0.0% | n/c | 1 | SEC ↗ |
| 35 | Invesco Ltd. | 1.29M | — | $40.93M | 0.0% | n/c | 1 | SEC ↗ |
| 36 | Invesco Ltd. | 1.29M | — | $40.93M | 0.0% | n/c | 1 | SEC ↗ |
| 37 | Baillie Gifford ✦ | 1.28M | +1.1% | $40.48M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 38 | Baillie Gifford ✦ | 1.28M | +1.1% | $40.48M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 39 | Baillie Gifford ✦ | 1.28M | +1.1% | $40.48M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 40 | Baillie Gifford ✦ | 1.28M | +1.1% | $40.48M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 41 | UBS AM, a distinct business unit of… | 1.17M | — | $37.21M | 0.0% | n/c | 1 | SEC ↗ |
| 42 | UBS AM, a distinct business unit of… | 1.17M | — | $37.21M | 0.0% | n/c | 1 | SEC ↗ |
| 43 | UBS AM, a distinct business unit of… | 1.17M | — | $37.21M | 0.0% | n/c | 1 | SEC ↗ |
| 44 | UBS AM, a distinct business unit of… | 1.17M | — | $37.21M | 0.0% | n/c | 1 | SEC ↗ |
| 45 | UBS AM, a distinct business unit of… | 1.17M | — | $37.21M | 0.0% | n/c | 1 | SEC ↗ |
| 46 | UBS AM, a distinct business unit of… | 1.17M | — | $37.21M | 0.0% | n/c | 1 | SEC ↗ |
| 47 | UBS AM, a distinct business unit of… | 1.17M | — | $37.21M | 0.0% | n/c | 1 | SEC ↗ |
| 48 | UBS AM, a distinct business unit of… | 1.17M | — | $37.21M | 0.0% | n/c | 1 | SEC ↗ |
| 49 | UBS AM, a distinct business unit of… | 1.17M | — | $37.21M | 0.0% | n/c | 1 | SEC ↗ |
| 50 | Morgan Stanley ✦ | 866.36K | -41.9% | $27.48M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 51 | Morgan Stanley ✦ | 866.36K | -41.9% | $27.48M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 52 | Morgan Stanley ✦ | 866.36K | -41.9% | $27.48M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 53 | Morgan Stanley ✦ | 866.36K | -41.9% | $27.48M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 54 | Morgan Stanley ✦ | 866.36K | -41.9% | $27.48M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 55 | Morgan Stanley ✦ | 866.36K | -41.9% | $27.48M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 56 | Morgan Stanley ✦ | 866.36K | -41.9% | $27.48M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 57 | Morgan Stanley ✦ | 866.36K | -41.9% | $27.48M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 58 | American Century Companies Inc | 865.63K | — | $27.46M | 0.0% | n/c | 1 | SEC ↗ |
| 59 | Dimensional Fund Advisors Lp | 815.37K | — | $25.86M | 0.0% | n/c | 1 | SEC ↗ |
| 60 | Dimensional Fund Advisors Lp | 815.37K | — | $25.86M | 0.0% | n/c | 1 | SEC ↗ |
| 61 | Dimensional Fund Advisors Lp | 815.37K | — | $25.86M | 0.0% | n/c | 1 | SEC ↗ |
| 62 | Dimensional Fund Advisors Lp | 815.37K | — | $25.86M | 0.0% | n/c | 1 | SEC ↗ |
| 63 | Wellington Management ✦ | 813.12K | +171.2% | $25.79M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 64 | Wellington Management ✦ | 813.12K | +171.2% | $25.79M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 65 | Wellington Management ✦ | 813.12K | +171.2% | $25.79M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 66 | Wellington Management ✦ | 813.12K | +171.2% | $25.79M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 67 | Wellington Management ✦ | 813.12K | +171.2% | $25.79M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 68 | Wellington Management ✦ | 813.12K | +171.2% | $25.79M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 69 | UBS Group AG | 662.32K | — | $21.01M | 0.0% | n/c | 1 | SEC ↗ |
| 70 | UBS Group AG | 662.32K | — | $21.01M | 0.0% | n/c | 1 | SEC ↗ |
| 71 | UBS Group AG | 662.32K | — | $21.01M | 0.0% | n/c | 1 | SEC ↗ |
| 72 | UBS Group AG | 662.32K | — | $21.01M | 0.0% | n/c | 1 | SEC ↗ |
| 73 | UBS Group AG | 662.32K | — | $21.01M | 0.0% | n/c | 1 | SEC ↗ |
| 74 | Jennison Associates Llc | 618.93K | — | $19.63M | 0.0% | n/c | 1 | SEC ↗ |
| 75 | Jennison Associates Llc | 618.93K | — | $19.63M | 0.0% | n/c | 1 | SEC ↗ |
| 76 | New York State Common Retirement… | 591.18K | — | $18.75M | 0.0% | n/c | 1 | SEC ↗ |
| 77 | Balyasny Asset Management L.P. | 579.37K | — | $18.38M | 0.0% | n/c | 1 | SEC ↗ |
| 78 | Charles Schwab Investment… | 548.39K | — | $17.39M | 0.0% | n/c | 1 | SEC ↗ |
| 79 | Northern Trust Corp | 504.84K | — | $16.01M | 0.0% | n/c | 1 | SEC ↗ |
| 80 | Northern Trust Corp | 504.84K | — | $16.01M | 0.0% | n/c | 1 | SEC ↗ |
| 81 | Northern Trust Corp | 504.84K | — | $16.01M | 0.0% | n/c | 1 | SEC ↗ |
| 82 | Northern Trust Corp | 504.84K | — | $16.01M | 0.0% | n/c | 1 | SEC ↗ |
| 83 | Northern Trust Corp | 504.84K | — | $16.01M | 0.0% | n/c | 1 | SEC ↗ |
| 84 | Northern Trust Corp | 504.84K | — | $16.01M | 0.0% | n/c | 1 | SEC ↗ |
| 85 | Bnp Paribas Financial Markets | 415.61K | — | $13.18M | 0.0% | n/c | 1 | SEC ↗ |
| 86 | Citigroup Inc | 401.28K | — | $12.73M | 0.0% | n/c | 1 | SEC ↗ |
| 87 | Citigroup Inc | 401.28K | — | $12.73M | 0.0% | n/c | 1 | SEC ↗ |
| 88 | Bank Of America Corp /De/ | 399.35K | — | $12.67M | 0.0% | n/c | 1 | SEC ↗ |
| 89 | Bank Of America Corp /De/ | 399.35K | — | $12.67M | 0.0% | n/c | 1 | SEC ↗ |
| 90 | Bank Of America Corp /De/ | 399.35K | — | $12.67M | 0.0% | n/c | 1 | SEC ↗ |
| 91 | Bank Of America Corp /De/ | 399.35K | — | $12.67M | 0.0% | n/c | 1 | SEC ↗ |
| 92 | Bank Of America Corp /De/ | 399.35K | — | $12.67M | 0.0% | n/c | 1 | SEC ↗ |
| 93 | Bank Of America Corp /De/ | 399.35K | — | $12.67M | 0.0% | n/c | 1 | SEC ↗ |
| 94 | Aberdeen Group plc | 308.12K | — | $9.77M | 0.0% | n/c | 1 | SEC ↗ |
| 95 | Nuveen, LLC | 290.56K | — | $9.22M | 0.0% | n/c | 1 | SEC ↗ |
| 96 | Nuveen, LLC | 290.56K | — | $9.22M | 0.0% | n/c | 1 | SEC ↗ |
| 97 | Sei Investments Co | 270.10K | — | $8.57M | 0.0% | n/c | 1 | SEC ↗ |
| 98 | Sei Investments Co | 270.10K | — | $8.57M | 0.0% | n/c | 1 | SEC ↗ |
| 99 | Pictet Asset Management Holding SA | 222.65K | — | $7.30M | 0.0% | n/c | 1 | SEC ↗ |
| 100 | JPMorgan Chase ✦ | 215.15K | -89.4% | $6.82M | 0.0% | ▼ Trim | 2 | SEC ↗ |
“Their weight” = the position's share of that manager's reported 13F equity value — the conviction measure. ✦ = curated manager.
New buyers
| No new tracked buyers this quarter. |
Exited
| Point72 Asset Management | $14.92M | was 0.0% |
| Two Sigma Investments | $2.08M | was 0.0% |
| Marshall Wace | $1.24M | was 0.0% |
Full-market context: across ALL 13F filers (SEC structured data, Q1 2026): 279 holders, 76.80M shares, $3.56B reported. This is a different, older period than the tracked-universe figures above and the two are never mixed.
What else this security's tracked holders most often hold — shared-ownership counts, not fundamental relationships.
Open-market purchases (P)
No open-market insider purchases in our coverage window.
Open-market sales (S)
Officer · 854 sh · $120,220
Officer · 669 sh · $93,035
Officer · 1.60K sh · $222,227
Officer · 1.97K sh · $273,265
Officer · 1.36K sh · $189,130
Officer · 4.05K sh · $562,661
Officer, Director · 6.64K sh · $923,259
Officer · 14.21K sh · $1.84M
Officer · 2.00K sh · $245,162
Officer · 6.30K sh · $761,860
Awards, exercises and tax withholding are never counted as buys or sales here. Methodology