Security record · archived quarter
TSHA
Taysha Gene Therapies, Inc. · Healthcare · Biotechnology
90Tracked holders
0Δ holders
135.71MShares held
$746.41MReported value
+2New positions
−1Exits
Momentum inputs (comparable managers): holder breadth 0.0% · share flow +1.0% · net new positions +1.1% — formula
All ownership figures: tracked 13F managers only, common-stock positions, reporting period Q4 2025
Ownership over time
| Quarter | Holders | Δ | Shares | Reported value | New | Exits |
|---|---|---|---|---|---|---|
| Q2 2026 | 85 | +6 | 146.63M | $997.83M | +12 | −5 |
| Q1 2026 | 81 | -9 | 130.93M | $584.01M | +4 | −14 |
| Q4 2025 | 90 | 0 | 135.71M | $746.41M | +2 | −1 |
| Q3 2025 | 18 | -1 | 108.64M | $355.25M | — | −1 |
| Q2 2025 | 16 | +5 | 65.80M | $152.01M | +5 | — |
| Q1 2025 | 8 | -4 | 14.26M | $19.83M | +1 | −5 |
| Q4 2024 | 12 | +5 | 19.11M | $33.06M | +5 | — |
| Q3 2024 | 6 | 0 | 7.50M | $15.08M | +2 | −2 |
| Q2 2024 | 6 | — | 5.37M | $12.04M | — | — |
Who holds it · Q4 2025
| # | Manager | Shares | Δ shares | Value | Their weight | Held | ||
|---|---|---|---|---|---|---|---|---|
| 1 | BlackRock ✦ (passive) | 18.64M | +13.9% | $102.54M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 2 | BlackRock ✦ (passive) | 18.64M | +13.9% | $102.54M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 3 | BlackRock ✦ (passive) | 18.64M | +13.9% | $102.54M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 4 | BlackRock ✦ (passive) | 18.64M | +13.9% | $102.54M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 5 | BlackRock ✦ (passive) | 18.64M | +13.9% | $102.54M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 6 | BlackRock ✦ (passive) | 18.64M | +13.9% | $102.54M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 7 | BlackRock ✦ (passive) | 18.64M | +13.9% | $102.54M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 8 | BlackRock ✦ (passive) | 18.64M | +13.9% | $102.54M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 9 | BlackRock ✦ (passive) | 18.64M | +13.9% | $102.54M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 10 | BlackRock ✦ (passive) | 18.64M | +13.9% | $102.54M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 11 | BlackRock ✦ (passive) | 18.64M | +13.9% | $102.54M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 12 | Morgan Stanley ✦ | 18.08M | -6.4% | $99.43M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 13 | Morgan Stanley ✦ | 18.08M | -6.4% | $99.43M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 14 | Morgan Stanley ✦ | 18.08M | -6.4% | $99.43M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 15 | Morgan Stanley ✦ | 18.08M | -6.4% | $99.43M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 16 | Morgan Stanley ✦ | 18.08M | -6.4% | $99.43M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 17 | Goldman Sachs Group ✦ | 13.69M | +2.3% | $75.31M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 18 | Goldman Sachs Group ✦ | 13.69M | +2.3% | $75.31M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 19 | Fidelity (FMR) ✦ | 13.53M | -7.3% | $74.41M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 20 | Fidelity (FMR) ✦ | 13.53M | -7.3% | $74.41M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 21 | Fidelity (FMR) ✦ | 13.53M | -7.3% | $74.41M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 22 | The Vanguard Group ✦ (passive) | 13.27M | +3.2% | $72.97M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 23 | The Vanguard Group ✦ (passive) | 13.27M | +3.2% | $72.97M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 24 | The Vanguard Group ✦ (passive) | 13.27M | +3.2% | $72.97M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 25 | The Vanguard Group ✦ (passive) | 13.27M | +3.2% | $72.97M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 26 | The Vanguard Group ✦ (passive) | 13.27M | +3.2% | $72.97M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 27 | State Street Global Advisors ✦ (passive) | 10.79M | +49.1% | $59.35M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 28 | Barclays Plc | 5.54M | — | $30.46M | 0.0% | n/c | 1 | SEC ↗ |
| 29 | Geode Capital Management ✦ (passive) | 5.39M | +4.1% | $29.63M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 30 | Geode Capital Management ✦ (passive) | 5.39M | +4.1% | $29.63M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 31 | D. E. Shaw & Co. ✦ | 4.01M | +48.3% | $22.07M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 32 | D. E. Shaw & Co. ✦ | 4.01M | +48.3% | $22.07M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 33 | Point72 Asset Management ✦ | 3.87M | -47.2% | $21.28M | 0.0% | ▼ Trim | 4 | SEC ↗ |
| 34 | Healthcare Of Ontario Pension Plan… | 3.72M | — | $20.47M | 0.0% | n/c | 1 | SEC ↗ |
| 35 | Millennium Management ✦ | 3.18M | -21.0% | $17.48M | 0.0% | ▼ Trim | 5 | SEC ↗ |
| 36 | Charles Schwab Investment… | 1.90M | — | $10.47M | 0.0% | n/c | 1 | SEC ↗ |
| 37 | Citadel Advisors ✦ | 1.85M | +405.0% | $10.20M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 38 | Citadel Advisors ✦ | 1.85M | +405.0% | $10.20M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 39 | Norges Bank ✦ (passive) | 1.84M | New | $10.11M | 0.0% | New | 1 | SEC ↗ |
| 40 | Invesco Ltd. | 1.33M | — | $7.33M | 0.0% | n/c | 1 | SEC ↗ |
| 41 | Invesco Ltd. | 1.33M | — | $7.33M | 0.0% | n/c | 1 | SEC ↗ |
| 42 | Invesco Ltd. | 1.33M | — | $7.33M | 0.0% | n/c | 1 | SEC ↗ |
| 43 | Invesco Ltd. | 1.33M | — | $7.33M | 0.0% | n/c | 1 | SEC ↗ |
| 44 | Adage Capital Partners ✦ | 1.33M | -60.1% | $7.30M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 45 | Northern Trust Corp | 1.24M | — | $6.81M | 0.0% | n/c | 1 | SEC ↗ |
| 46 | Northern Trust Corp | 1.24M | — | $6.81M | 0.0% | n/c | 1 | SEC ↗ |
| 47 | Northern Trust Corp | 1.24M | — | $6.81M | 0.0% | n/c | 1 | SEC ↗ |
| 48 | Northern Trust Corp | 1.24M | — | $6.81M | 0.0% | n/c | 1 | SEC ↗ |
| 49 | Northern Trust Corp | 1.24M | — | $6.81M | 0.0% | n/c | 1 | SEC ↗ |
| 50 | Bank Of America Corp /De/ | 1.15M | — | $6.34M | 0.0% | n/c | 1 | SEC ↗ |
| 51 | Bank Of America Corp /De/ | 1.15M | — | $6.34M | 0.0% | n/c | 1 | SEC ↗ |
| 52 | Bank Of America Corp /De/ | 1.15M | — | $6.34M | 0.0% | n/c | 1 | SEC ↗ |
| 53 | Aberdeen Group plc | 1.02M | — | $5.62M | 0.0% | n/c | 1 | SEC ↗ |
| 54 | JPMorgan Chase ✦ | 774.41K | +30.7% | $4.26M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 55 | JPMorgan Chase ✦ | 774.41K | +30.7% | $4.26M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 56 | JPMorgan Chase ✦ | 774.41K | +30.7% | $4.26M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 57 | JPMorgan Chase ✦ | 774.41K | +30.7% | $4.26M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 58 | JPMorgan Chase ✦ | 774.41K | +30.7% | $4.26M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 59 | Wellington Management ✦ | 711.24K | +25.2% | $3.91M | 0.0% | ▲ Add | 6 | SEC ↗ |
| 60 | Wellington Management ✦ | 711.24K | +25.2% | $3.91M | 0.0% | ▲ Add | 6 | SEC ↗ |
| 61 | Wellington Management ✦ | 711.24K | +25.2% | $3.91M | 0.0% | ▲ Add | 6 | SEC ↗ |
| 62 | Bank of New York Mellon Corp | 624.37K | — | $3.43M | 0.0% | n/c | 1 | SEC ↗ |
| 63 | Bank of New York Mellon Corp | 624.37K | — | $3.43M | 0.0% | n/c | 1 | SEC ↗ |
| 64 | Bank of New York Mellon Corp | 624.37K | — | $3.43M | 0.0% | n/c | 1 | SEC ↗ |
| 65 | Bank of New York Mellon Corp | 624.37K | — | $3.43M | 0.0% | n/c | 1 | SEC ↗ |
| 66 | Bank of New York Mellon Corp | 624.37K | — | $3.43M | 0.0% | n/c | 1 | SEC ↗ |
| 67 | Nuveen, LLC | 545.29K | — | $3.00M | 0.0% | n/c | 1 | SEC ↗ |
| 68 | Nuveen, LLC | 545.29K | — | $3.00M | 0.0% | n/c | 1 | SEC ↗ |
| 69 | Dimensional Fund Advisors Lp | 490.47K | — | $2.70M | 0.0% | n/c | 1 | SEC ↗ |
| 70 | Dimensional Fund Advisors Lp | 490.47K | — | $2.70M | 0.0% | n/c | 1 | SEC ↗ |
| 71 | Dimensional Fund Advisors Lp | 490.47K | — | $2.70M | 0.0% | n/c | 1 | SEC ↗ |
| 72 | Dimensional Fund Advisors Lp | 490.47K | — | $2.70M | 0.0% | n/c | 1 | SEC ↗ |
| 73 | Squarepoint Ops LLC | 471.58K | — | $2.59M | 0.0% | n/c | 1 | SEC ↗ |
| 74 | Hrt Financial Lp | 409.25K | — | $2.25M | 0.0% | n/c | 1 | SEC ↗ |
| 75 | UBS Group AG | 383.04K | — | $2.11M | 0.0% | n/c | 1 | SEC ↗ |
| 76 | UBS Group AG | 383.04K | — | $2.11M | 0.0% | n/c | 1 | SEC ↗ |
| 77 | UBS Group AG | 383.04K | — | $2.11M | 0.0% | n/c | 1 | SEC ↗ |
| 78 | Two Sigma Investments ✦ | 351.13K | +431.2% | $1.93M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 79 | Wells Fargo & Company/Mn | 305.09K | — | $1.68M | 0.0% | n/c | 1 | SEC ↗ |
| 80 | Wells Fargo & Company/Mn | 305.09K | — | $1.68M | 0.0% | n/c | 1 | SEC ↗ |
| 81 | Wells Fargo & Company/Mn | 305.09K | — | $1.68M | 0.0% | n/c | 1 | SEC ↗ |
| 82 | Focus Partners Wealth | 295.52K | — | $1.63M | 0.0% | n/c | 1 | SEC ↗ |
| 83 | American Century Companies Inc | 288.54K | — | $1.59M | 0.0% | n/c | 1 | SEC ↗ |
| 84 | Ensign Peak Advisors, Inc | 275.11K | — | $1.51M | 0.0% | n/c | 1 | SEC ↗ |
| 85 | Swiss National Bank | 268.80K | — | $1.48M | 0.0% | n/c | 1 | SEC ↗ |
| 86 | Nomura Holdings Inc | 259.34K | — | $1.43M | 0.0% | n/c | 1 | SEC ↗ |
| 87 | Rhumbline Advisers | 257.44K | — | $1.42M | 0.0% | n/c | 1 | SEC ↗ |
| 88 | Voya Investment Management Llc | 218.19K | — | $1.20M | 0.0% | n/c | 1 | SEC ↗ |
| 89 | Voya Investment Management Llc | 218.19K | — | $1.20M | 0.0% | n/c | 1 | SEC ↗ |
| 90 | Victory Capital Management Inc | 195.76K | — | $1.08M | 0.0% | n/c | 1 | SEC ↗ |
| 91 | Alliancebernstein L.P. | 179.64K | — | $988,020 | 0.0% | n/c | 1 | SEC ↗ |
| 92 | Bnp Paribas Financial Markets | 172.48K | — | $948,651 | 0.0% | n/c | 1 | SEC ↗ |
| 93 | Renaissance Technologies ✦ | 171.10K | New | $941,050 | 0.0% | New | 1 | SEC ↗ |
| 94 | AQR Capital Management ✦ | 168.86K | +11.8% | $928,742 | 0.0% | ▲ Add | 6 | SEC ↗ |
| 95 | AQR Capital Management ✦ | 168.86K | +11.8% | $928,742 | 0.0% | ▲ Add | 6 | SEC ↗ |
| 96 | AQR Capital Management ✦ | 168.86K | +11.8% | $928,742 | 0.0% | ▲ Add | 6 | SEC ↗ |
| 97 | AQR Capital Management ✦ | 168.86K | +11.8% | $928,742 | 0.0% | ▲ Add | 6 | SEC ↗ |
| 98 | AQR Capital Management ✦ | 168.86K | +11.8% | $928,742 | 0.0% | ▲ Add | 6 | SEC ↗ |
| 99 | UBS AM, a distinct business unit of… | 167.50K | — | $921,250 | 0.0% | n/c | 1 | SEC ↗ |
| 100 | UBS AM, a distinct business unit of… | 167.50K | — | $921,250 | 0.0% | n/c | 1 | SEC ↗ |
“Their weight” = the position's share of that manager's reported 13F equity value — the conviction measure. ✦ = curated manager.
New buyers
| Norges Bank | $10.11M | 0.0% |
| Renaissance Technologies | $941,050 | 0.0% |
Exited
| Marshall Wace | $1.56M | was 0.0% |
Full-market context: across ALL 13F filers (SEC structured data, Q1 2026): 190 holders, 265.00M shares, $1.21B reported. This is a different, older period than the tracked-universe figures above and the two are never mixed.
Frequently co-owned
What else this security's tracked holders most often hold — shared-ownership counts, not fundamental relationships.
Provenance: Ownership from parsed 13F common-stock positions (tracked universe, comparable sets for changes); insider rows from Forms 3/4/5; stakes from Schedules 13D/13G; every filing links to its original on SEC EDGAR.
Reporting period: Q4 2025 ·
Methodology ·
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