Security record · archived quarter
SEPN
Septerna Inc · Healthcare · Biotechnology
52Tracked holders
-1Δ holders
11.23MShares held
$269.91MReported value
+8New positions
−9Exits
Momentum inputs (comparable managers):
holder breadth -1.9% ·
share flow +18.6% ·
net new positions -1.9%
· formula
Concentrated accumulation: rising shares among fewer holders
All ownership figures: tracked 13F managers only, common-stock positions, reporting period Q1 2026
Ownership over time
Who holds it · Q1 2026
| # | Manager | Shares | Δ shares | Value | Their weight | Held | ||
|---|---|---|---|---|---|---|---|---|
| 1 | Goldman Sachs Group ✦ | 2.91M | +7.0% | $69.84M | 0.0% | ▲ Add | 3 | SEC ↗ ×2 |
| 2 | BlackRock ✦ (passive) | 1.82M | +1.2% | $43.79M | 0.0% | ▲ Add | 4 | SEC ↗ ×8 |
| 3 | Vanguard Capital Management Llc | 1.20M | n/a | $28.76M | 0.0% | n/c | 1 | SEC ↗ |
| 4 | PRIMECAP Management ✦ | 1.05M | +92.1% | $25.20M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 5 | Janus Henderson Group Plc | 890.75K | New | $21.33M | 0.0% | New | 1 | SEC ↗ |
| 6 | Geode Capital Management ✦ (passive) | 645.15K | +12.6% | $15.51M | 0.0% | ▲ Add | 6 | SEC ↗ ×2 |
| 7 | State Street Global Advisors ✦ (passive) | 631.45K | +16.9% | $15.17M | 0.0% | ▲ Add | 6 | SEC ↗ |
| 8 | Balyasny Asset Management L.P. | 236.68K | +6527.8% | $5.69M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 9 | Universal- Beteiligungs- und… | 224.00K | +0.6% | $5.38M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 10 | Charles Schwab Investment… | 181.58K | -3.0% | $4.36M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 11 | Northern Trust Corp | 164.53K | +6.7% | $3.95M | 0.0% | ▲ Add | 2 | SEC ↗ ×4 |
| 12 | Millennium Management ✦ | 124.10K | +15.5% | $2.98M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 13 | UBS Group AG | 116.98K | +70.0% | $2.81M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 14 | Morgan Stanley ✦ | 110.53K | +6.3% | $2.66M | 0.0% | ▲ Add | 3 | SEC ↗ ×6 |
| 15 | Federated Hermes, Inc. | 89.30K | +13.2% | $2.15M | 0.0% | ▲ Add | 2 | SEC ↗ ×3 |
| 16 | Invesco Ltd. | 82.87K | -48.9% | $1.99M | 0.0% | ▼ Trim | 2 | SEC ↗ ×4 |
| 17 | JPMorgan Chase ✦ | 84.67K | +23.9% | $1.97M | 0.0% | ▲ Add | 3 | SEC ↗ ×4 |
| 18 | Two Sigma Investments ✦ | 75.37K | -18.8% | $1.81M | 0.0% | ▼ Trim | 5 | SEC ↗ |
| 19 | American Century Companies Inc | 61.29K | +20.9% | $1.47M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 20 | Bank of New York Mellon Corp | 58.71K | +6.1% | $1.41M | 0.0% | ▲ Add | 2 | SEC ↗ ×5 |
| 21 | Marshall Wace ✦ | 39.84K | -82.4% | $957,354 | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 22 | Renaissance Technologies ✦ | 37.70K | New | $905,931 | 0.0% | New | 1 | SEC ↗ |
| 23 | Alyeska Investment Group, L.P. | 35.00K | 0.0% | $841,050 | 0.0% | Held | 2 | SEC ↗ |
| 24 | Nuveen, LLC | 29.18K | +13.1% | $701,099 | 0.0% | ▲ Add | 2 | SEC ↗ ×2 |
| 25 | T. Rowe Price ✦ | 28.08K | +10.3% | $675,000 | 0.0% | ▲ Add | 6 | SEC ↗ |
| 26 | Rhumbline Advisers | 26.60K | +0.7% | $639,285 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 27 | Bank Of America Corp /De/ | 25.97K | -30.9% | $624,131 | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 28 | Adage Capital Partners ✦ | 24.00K | New | $576,720 | 0.0% | New | 1 | SEC ↗ |
| 29 | Fidelity (FMR) ✦ | 23.45K | +609.0% | $563,407 | 0.0% | ▲ Add | 4 | SEC ↗ |
| 30 | Alliancebernstein L.P. | 19.60K | 0.0% | $546,448 | 0.0% | Held | 2 | SEC ↗ |
| 31 | Barclays Plc | 22.71K | -40.5% | $545,818 | 0.0% | ▼ Trim | 2 | SEC ↗ ×3 |
| 32 | Swiss National Bank | 22.10K | New | $531,063 | 0.0% | New | 1 | SEC ↗ |
| 33 | Squarepoint Ops LLC | 18.08K | +21.8% | $434,534 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 34 | Deutsche Bank Ag\ | 16.84K | +13.2% | $404,737 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 35 | AQR Capital Management ✦ | 15.38K | +96.5% | $369,461 | 0.0% | ▲ Add | 2 | SEC ↗ ×4 |
| 36 | Osaic Holdings, Inc. | 12.70K | 0.0% | $305,132 | 0.0% | ▲ Add | 2 | SEC ↗ ×2 |
| 37 | Man Group plc | 11.86K | New | $284,948 | 0.0% | New | 1 | SEC ↗ |
| 38 | Russell Investments Group, Ltd. | 11.52K | -24.8% | $276,708 | 0.0% | ▼ Trim | 2 | SEC ↗ ×7 |
| 39 | Massachusetts Financial Services Co… | 10.38K | New | $249,480 | 0.0% | New | 1 | SEC ↗ ×2 |
| 40 | MIRAE ASSET GLOBAL ETFS HOLDINGS… | 10.02K | +0.9% | $240,805 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 41 | Wells Fargo & Company/Mn | 9.87K | -62.8% | $237,152 | 0.0% | ▼ Trim | 2 | SEC ↗ ×2 |
| 42 | Citigroup Inc | 9.20K | -3.8% | $220,956 | 0.0% | ▼ Trim | 2 | SEC ↗ ×2 |
| 43 | Legal & General Group Plc | 5.74K | +194.9% | $137,811 | 0.0% | ▲ Add | 2 | SEC ↗ ×2 |
| 44 | New York State Common Retirement… | 5.60K | 0.0% | $134,568 | 0.0% | Held | 2 | SEC ↗ |
| 45 | Bnp Paribas Financial Markets | 5.36K | -1.6% | $128,825 | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 46 | Mirae Asset Global Investments Co.… | 2.33K | +7.3% | $56,110 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 47 | California State Teachers… | 1.16K | -12.1% | $27,803 | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 48 | Cwm, Llc | 894 | +0.7% | $21,483 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 49 | Zurcher Kantonalbank (Zurich… | 508 | New | $12,207 | 0.0% | New | 1 | SEC ↗ |
| 50 | Us Bancorp \De\ | 197 | +3.7% | $4,734 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 51 | UBS AM, a distinct business unit of… | 155 | New | $3,725 | 0.0% | New | 1 | SEC ↗ |
| 52 | Pnc Financial Services Group, Inc. | 43 | -78.3% | $1,033 | 0.0% | ▼ Trim | 2 | SEC ↗ |
“Their weight” = the position's share of that manager's reported 13F equity value: the conviction measure. ✦ = curated manager.
New buyers
| Janus Henderson Group Plc | $21.33M | 0.0% |
| Renaissance Technologies | $905,931 | 0.0% |
| Adage Capital Partners | $576,720 | 0.0% |
| Swiss National Bank | $531,063 | 0.0% |
| Man Group plc | $284,948 | 0.0% |
| Massachusetts Financial… | $249,480 | 0.0% |
| Zurcher Kantonalbank (Zurich… | $12,207 | 0.0% |
| UBS AM, a distinct business… | $3,725 | 0.0% |
Exited
| Citadel Advisors | $2.12M | was 0.0% |
| Jane Street Group, Llc | $1.23M | was 0.0% |
| Tudor Investment Corp Et Al | $503,318 | was 0.0% |
| Franklin Resources Inc | $469,834 | was 0.0% |
| Ameriprise Financial Inc | $392,829 | was 0.0% |
| Bank Of Nova Scotia | $231,404 | was 0.0% |
| Group One Trading Llc | $26,319 | was 0.0% |
| Royal Bank Of Canada | $18,000 | was 0.0% |
| Daiwa Securities Group Inc. | $4,000 | was 0.0% |
Full-market context: across ALL 13F filers (SEC structured data, Q1 2026): 123 holders, 45.64M shares, $1.09B reported. This is a different, older period than the tracked-universe figures above and the two are never mixed.
Frequently co-owned
What else this security's tracked holders most often hold: shared-ownership counts, not fundamental relationships.
Open-market purchases (P)
No open-market insider purchases in our coverage window.
Open-market sales (S)
Oct 15
Bhatt Elizabeth
Officer · 2.91K sh · $109,307
Oct 15
Bhatt Elizabeth
Officer · 1.09K sh · $40,337
Aug 12
Third Rock Ventures V, L.P.
10% owner · 141 sh · $7,202
Aug 12
RA CAPITAL MANAGEMENT, L.P.
Director, 10% owner · 746.50K sh · $31.73M
Aug 12
RA CAPITAL MANAGEMENT, L.P.
Director, 10% owner · 746.50K sh · $31.73M
Aug 12
Third Rock Ventures V, L.P.
10% owner · 147.06K sh · $7.39M
Aug 11
Bhatt Elizabeth
Officer · 25.00K sh · $1.10M
Awards, exercises and tax withholding are never counted as buys or sales here. Methodology
Aug 14
SC 13G/A: DRIEHAUS CAPITAL MANAGEMENT LLC
Aug 14
SC 13D/A: RA CAPITAL MANAGEMENT, L.P.
11.8% of class · View original SEC filing ↗
Provenance: Ownership from parsed 13F common-stock positions (tracked universe, comparable sets for changes); insider rows from Forms 3/4/5; stakes from Schedules 13D/13G; every filing links to its original on SEC EDGAR.
Reporting period: Q1 2026 ·
Methodology ·
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