证券记录 · 已归档季度
SEPN
Septerna Inc · Healthcare · Biotechnology
53被追踪持有人
+4Δ持有人
9.79M持有股份
$272.84M报告持仓市值
+4新建仓位
−0清仓
动量输入（同类管理人）：
持有人广度 +8.2% ·
股份流向 +30.0% ·
净新建仓位 +7.5%
· 公式
广泛增持：持股数量上升，持有人数量增加
所有持股数据：仅限已追踪的 13F 管理人，普通股持仓，报告期 Q4 2025
持股变化趋势
持有人 · Q4 2025
| # | 管理人 | 股份 | Δ股份 | 价值 | 其权重 | 持有 | ||
|---|---|---|---|---|---|---|---|---|
| 1 | Goldman Sachs Group ✦ | 2.72M | +86.6% | $75.70M | 0.0% | ▲ Add | 2 | SEC ↗ ×2 |
| 2 | BlackRock ✦ (被动) | 1.80M | +23.4% | $50.22M | 0.0% | ▲ Add | 3 | SEC ↗ ×8 |
| 3 | The Vanguard Group ✦ (被动) | 1.51M | -0.7% | $42.05M | 0.0% | ▼ Trim | 3 | SEC ↗ ×3 |
| 4 | Geode Capital Management ✦ (被动) | 572.73K | +5.0% | $15.97M | 0.0% | ▲ Add | 5 | SEC ↗ ×2 |
| 5 | PRIMECAP Management ✦ | 546.10K | 新增 | $15.23M | 0.0% | New | 1 | SEC ↗ |
| 6 | State Street Global Advisors ✦ (被动) | 540.03K | +28.9% | $15.06M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 7 | Marshall Wace ✦ | 226.90K | 新增 | $6.33M | 0.0% | New | 1 | SEC ↗ ×2 |
| 8 | Universal- Beteiligungs- und… | 222.70K | n/a | $6.21M | 0.0% | n/c | 1 | SEC ↗ |
| 9 | Charles Schwab Investment… | 187.24K | n/a | $5.22M | 0.0% | n/c | 1 | SEC ↗ |
| 10 | Invesco Ltd. | 162.01K | n/a | $4.52M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 11 | Northern Trust Corp | 154.20K | n/a | $4.30M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 12 | Millennium Management ✦ | 107.46K | -72.0% | $3.00M | 0.0% | ▼ Trim | 4 | SEC ↗ |
| 13 | Morgan Stanley ✦ | 103.98K | +91.0% | $2.90M | 0.0% | ▲ Add | 2 | SEC ↗ ×6 |
| 14 | Two Sigma Investments ✦ | 92.81K | +0.5% | $2.59M | 0.0% | ▲ Add | 4 | SEC ↗ |
| 15 | Federated Hermes, Inc. | 78.91K | n/a | $2.20M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 16 | Citadel Advisors ✦ | 75.94K | 新增 | $2.12M | 0.0% | New | 1 | SEC ↗ ×2 |
| 17 | UBS Group AG | 68.82K | n/a | $1.92M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 18 | JPMorgan Chase ✦ | 68.34K | +291.1% | $1.91M | 0.0% | ▲ Add | 2 | SEC ↗ ×3 |
| 19 | Bank of New York Mellon Corp | 55.33K | n/a | $1.54M | 0.0% | n/c | 1 | SEC ↗ ×5 |
| 20 | American Century Companies Inc | 50.69K | n/a | $1.41M | 0.0% | n/c | 1 | SEC ↗ |
| 21 | Jane Street Group, Llc | 44.07K | n/a | $1.23M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 22 | Barclays Plc | 38.15K | n/a | $1.06M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 23 | Bank Of America Corp /De/ | 37.59K | n/a | $1.05M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 24 | Alyeska Investment Group, L.P. | 35.00K | n/a | $975,800 | 0.0% | n/c | 1 | SEC ↗ |
| 25 | Wells Fargo & Company/Mn | 26.53K | n/a | $739,628 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 26 | Rhumbline Advisers | 26.42K | n/a | $736,552 | 0.0% | n/c | 1 | SEC ↗ |
| 27 | Nuveen, LLC | 25.80K | n/a | $719,248 | 0.0% | n/c | 1 | SEC ↗ |
| 28 | T. Rowe Price ✦ | 25.44K | -7.2% | $710,000 | 0.0% | ▼ Trim | 5 | SEC ↗ |
| 29 | Alliancebernstein L.P. | 19.60K | n/a | $546,448 | 0.0% | n/c | 1 | SEC ↗ |
| 30 | Tudor Investment Corp Et Al | 18.05K | n/a | $503,318 | 0.0% | n/c | 1 | SEC ↗ |
| 31 | Franklin Resources Inc | 16.85K | n/a | $469,834 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 32 | Russell Investments Group, Ltd. | 15.31K | n/a | $426,840 | 0.0% | n/c | 1 | SEC ↗ ×6 |
| 33 | Deutsche Bank Ag\ | 14.88K | n/a | $414,827 | 0.0% | n/c | 1 | SEC ↗ |
| 34 | Squarepoint Ops LLC | 14.85K | n/a | $413,934 | 0.0% | n/c | 1 | SEC ↗ |
| 35 | Ameriprise Financial Inc | 14.09K | n/a | $392,829 | 0.0% | n/c | 1 | SEC ↗ |
| 36 | Osaic Holdings, Inc. | 12.69K | n/a | $353,880 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 37 | MIRAE ASSET GLOBAL ETFS HOLDINGS… | 9.93K | n/a | $276,960 | 0.0% | n/c | 1 | SEC ↗ |
| 38 | Citigroup Inc | 9.56K | n/a | $266,561 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 39 | Bank Of Nova Scotia | 8.30K | n/a | $231,404 | 0.0% | n/c | 1 | SEC ↗ |
| 40 | AQR Capital Management ✦ | 7.83K | 新增 | $218,189 | 0.0% | New | 1 | SEC ↗ ×5 |
| 41 | New York State Common Retirement… | 5.60K | n/a | $156,128 | 0.0% | n/c | 1 | SEC ↗ |
| 42 | Bnp Paribas Financial Markets | 5.45K | n/a | $151,918 | 0.0% | n/c | 1 | SEC ↗ |
| 43 | Balyasny Asset Management L.P. | 3.57K | n/a | $99,559 | 0.0% | n/c | 1 | SEC ↗ |
| 44 | Fidelity (FMR) ✦ | 3.31K | -3.8% | $92,199 | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 45 | Mirae Asset Global Investments Co.… | 2.18K | n/a | $60,667 | 0.0% | n/c | 1 | SEC ↗ |
| 46 | Legal & General Group Plc | 1.95K | n/a | $54,168 | 0.0% | n/c | 1 | SEC ↗ |
| 47 | California State Teachers… | 1.32K | n/a | $36,690 | 0.0% | n/c | 1 | SEC ↗ |
| 48 | Group One Trading Llc | 944 | n/a | $26,319 | 0.0% | n/c | 1 | SEC ↗ |
| 49 | Cwm, Llc | 888 | n/a | $25,000 | 0.0% | n/c | 1 | SEC ↗ |
| 50 | Royal Bank Of Canada | 628 | n/a | $18,000 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 51 | Pnc Financial Services Group, Inc. | 198 | n/a | $5,520 | 0.0% | n/c | 1 | SEC ↗ |
| 52 | Us Bancorp \De\ | 190 | n/a | $5,297 | 0.0% | n/c | 1 | SEC ↗ |
| 53 | Daiwa Securities Group Inc. | 149 | n/a | $4,000 | 0.0% | n/c | 1 | SEC ↗ |
"持仓权重"指该仓位占该管理人13F申报股票组合市值的比例，即持仓信心指标。✦ = 精选管理人。
新增买入方
| PRIMECAP Management | $15.23M | 0.0% |
| Marshall Wace | $6.33M | 0.0% |
| Citadel Advisors | $2.12M | 0.0% |
| AQR Capital Management | $218,189 | 0.0% |
已清仓
| 本季度无被追踪的退出仓位。 |
全市场背景: 涵盖所有13F申报机构（SEC结构化数据， Q1 2026): 123 持有人, 45.64M 股份, $1.09B 已申报. 这是与上方被追踪全域数据不同的较早期间，两者从不混用。
常见共同持仓
持有该证券的受追踪机构最常同时持有的其他证券：基于共同持有计数，而非基本面关联。
公开市场买入 (P)
在我们的覆盖窗口内无内部人士公开市场买入记录。
公开市场卖出 (S)
Oct 15
Bhatt Elizabeth
Officer · 2.91K 股 · $109,307
Oct 15
Bhatt Elizabeth
Officer · 1.09K 股 · $40,337
Aug 12
Third Rock Ventures V, L.P.
10% owner · 141 股 · $7,202
Aug 12
RA CAPITAL MANAGEMENT, L.P.
Director, 10% owner · 746.50K 股 · $31.73M
Aug 12
RA CAPITAL MANAGEMENT, L.P.
Director, 10% owner · 746.50K 股 · $31.73M
Aug 12
Third Rock Ventures V, L.P.
10% owner · 147.06K 股 · $7.39M
Aug 11
Bhatt Elizabeth
Officer · 25.00K 股 · $1.10M
授予、行权及税务代扣代缴在本平台均不计入买入或卖出。 方法论
Aug 14
SC 13G/A: DRIEHAUS CAPITAL MANAGEMENT LLC
Aug 14
SC 13D/A: RA CAPITAL MANAGEMENT, L.P.
11.8% 占股份类别 · 查看 SEC 原始申报文件 ↗
数据来源: 持股数据来源于已解析的13F普通股持仓（被追踪范围，变动对比集）；内部人行为来自Form 3/4/5；重大持股来自Schedule 13D/13G；所有文件均链接至SEC EDGAR原始申报。
报告期: Q4 2025 ·
方法论 ·
通过API获取此数据