Security record · archived quarter
PRME
Prime Medicine, Inc. · Healthcare · Biotechnology
78Tracked holders
0Δ holders
56.37MShares held
$195.61MReported value
+1New positions
−1Exits
Momentum inputs (comparable managers): holder breadth 0.0% · share flow +17.6% · net new positions 0.0% — formula
All ownership figures: tracked 13F managers only, common-stock positions, reporting period Q4 2025
Ownership over time
| Quarter | Holders | Δ | Shares | Reported value | New | Exits |
|---|---|---|---|---|---|---|
| Q2 2026 | 77 | +1 | 62.17M | $229.38M | +6 | −6 |
| Q1 2026 | 80 | +2 | 55.31M | $192.04M | +9 | −7 |
| Q4 2025 | 78 | 0 | 56.37M | $195.61M | +1 | −1 |
| Q3 2025 | 18 | +3 | 30.74M | $170.29M | +3 | — |
| Q2 2025 | 12 | +1 | 18.57M | $45.87M | +1 | — |
| Q1 2025 | 8 | 0 | 10.06M | $20.03M | +1 | −1 |
| Q4 2024 | 8 | -1 | 11.48M | $33.53M | +2 | −3 |
| Q3 2024 | 8 | -1 | 11.29M | $43.71M | +1 | −2 |
| Q2 2024 | 9 | — | 11.11M | $57.12M | — | — |
Who holds it · Q4 2025
| # | Manager | Shares | Δ shares | Value | Their weight | Held | ||
|---|---|---|---|---|---|---|---|---|
| 1 | BlackRock ✦ (passive) | 8.27M | +46.3% | $28.69M | 0.0% | ▲ Add | 3 | SEC ↗ ×9 |
| 2 | The Vanguard Group ✦ (passive) | 6.47M | +31.4% | $22.44M | 0.0% | ▲ Add | 3 | SEC ↗ ×5 |
| 3 | ARK Investment Management ✦ | 5.37M | -2.0% | $18.63M | 0.1% | ▼ Trim | 7 | SEC ↗ |
| 4 | State Street Global Advisors ✦ (passive) | 5.10M | +293.0% | $17.68M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 5 | Sumitomo Mitsui Trust Group, Inc. | 3.25M | — | $11.26M | 0.0% | n/c | 1 | SEC ↗ |
| 6 | Balyasny Asset Management L.P. | 3.12M | — | $10.84M | 0.0% | n/c | 1 | SEC ↗ |
| 7 | Geode Capital Management ✦ (passive) | 2.63M | +48.8% | $9.12M | 0.0% | ▲ Add | 7 | SEC ↗ ×2 |
| 8 | UBS Group AG | 2.44M | — | $8.47M | 0.0% | n/c | 1 | SEC ↗ ×4 |
| 9 | Fidelity (FMR) ✦ | 2.18M | -22.6% | $7.55M | 0.0% | ▼ Trim | 3 | SEC ↗ ×3 |
| 10 | Goldman Sachs Group ✦ | 1.76M | +327.5% | $6.09M | 0.0% | ▲ Add | 2 | SEC ↗ ×2 |
| 11 | Two Sigma Investments ✦ | 1.63M | +264.0% | $5.65M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 12 | D. E. Shaw & Co. ✦ | 1.55M | -30.0% | $5.38M | 0.0% | ▼ Trim | 2 | SEC ↗ ×2 |
| 13 | Susquehanna International Group, Llp | 1.18M | — | $4.08M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 14 | Morgan Stanley ✦ | 1.17M | +60.0% | $4.06M | 0.0% | ▲ Add | 2 | SEC ↗ ×8 |
| 15 | Renaissance Technologies ✦ | 1.15M | +1.3% | $3.99M | 0.0% | ▲ Add | 4 | SEC ↗ |
| 16 | Charles Schwab Investment… | 936.82K | — | $3.25M | 0.0% | n/c | 1 | SEC ↗ |
| 17 | Northern Trust Corp | 842.15K | — | $2.92M | 0.0% | n/c | 1 | SEC ↗ ×5 |
| 18 | Hrt Financial Lp | 655.35K | — | $2.27M | 0.0% | n/c | 1 | SEC ↗ |
| 19 | Bank Of America Corp /De/ | 648.01K | — | $2.25M | 0.0% | n/c | 1 | SEC ↗ ×4 |
| 20 | Point72 Asset Management ✦ | 551.03K | New | $1.91M | 0.0% | New | 1 | SEC ↗ |
| 21 | JPMorgan Chase ✦ | 435.71K | +402.1% | $1.51M | 0.0% | ▲ Add | 2 | SEC ↗ ×4 |
| 22 | AQR Capital Management ✦ | 415.82K | +0.4% | $1.44M | 0.0% | ▲ Add | 5 | SEC ↗ ×5 |
| 23 | HighTower Advisors, LLC | 400.11K | — | $1.39M | 0.0% | n/c | 1 | SEC ↗ |
| 24 | Barclays Plc | 363.83K | — | $1.26M | 0.0% | n/c | 1 | SEC ↗ |
| 25 | Wells Fargo & Company/Mn | 294.50K | — | $1.02M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 26 | Nuveen, LLC | 251.64K | — | $873,177 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 27 | Wellington Management ✦ | 248.23K | +20.9% | $861,348 | 0.0% | ▲ Add | 2 | SEC ↗ ×3 |
| 28 | Bank of New York Mellon Corp | 246.77K | — | $856,292 | 0.0% | n/c | 1 | SEC ↗ ×5 |
| 29 | Squarepoint Ops LLC | 218.04K | — | $756,606 | 0.0% | n/c | 1 | SEC ↗ |
| 30 | Swiss National Bank | 170.10K | — | $590,247 | 0.0% | n/c | 1 | SEC ↗ |
| 31 | Deutsche Bank Ag\ | 147.94K | — | $513,362 | 0.0% | n/c | 1 | SEC ↗ |
| 32 | Rockefeller Capital Management L.P. | 121.39K | — | $421,226 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 33 | FIL Ltd | 115.60K | — | $401,139 | 0.0% | n/c | 1 | SEC ↗ |
| 34 | MIRAE ASSET GLOBAL ETFS HOLDINGS… | 115.06K | — | $398,930 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 35 | Citadel Advisors ✦ | 112.87K | -87.5% | $391,659 | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 36 | Alliancebernstein L.P. | 108.69K | — | $377,154 | 0.0% | n/c | 1 | SEC ↗ |
| 37 | Rhumbline Advisers | 108.41K | — | $376,170 | 0.0% | n/c | 1 | SEC ↗ |
| 38 | T. Rowe Price ✦ | 104.55K | +40.3% | $363,000 | 0.0% | ▲ Add | 7 | SEC ↗ |
| 39 | Group One Trading Llc | 103.21K | — | $358,149 | 0.0% | n/c | 1 | SEC ↗ |
| 40 | UBS AM, a distinct business unit of… | 99.10K | — | $343,877 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 41 | Qube Research & Technologies Ltd | 94.67K | — | $328,505 | 0.0% | n/c | 1 | SEC ↗ |
| 42 | Td Asset Management Inc | 94.15K | — | $326,694 | 0.0% | n/c | 1 | SEC ↗ |
| 43 | California State Teachers… | 86.93K | — | $301,644 | 0.0% | n/c | 1 | SEC ↗ |
| 44 | Dimensional Fund Advisors Lp | 84.05K | — | $291,667 | 0.0% | n/c | 1 | SEC ↗ |
| 45 | Legal & General Group Plc | 80.75K | — | $280,198 | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 46 | Corient Private Wealth LP | 77.55K | — | $269,112 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 47 | Janus Henderson Group Plc | 60.90K | — | $210,410 | 0.0% | n/c | 1 | SEC ↗ |
| 48 | Invesco Ltd. | 56.78K | — | $197,023 | 0.0% | n/c | 1 | SEC ↗ ×4 |
| 49 | Ameriprise Financial Inc | 54.08K | — | $187,666 | 0.0% | n/c | 1 | SEC ↗ |
| 50 | Millennium Management ✦ | 51.34K | -96.4% | $178,132 | 0.0% | ▼ Trim | 7 | SEC ↗ |
| 51 | Citigroup Inc | 51.23K | — | $177,764 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 52 | Tidal Investments LLC | 50.24K | — | $174,347 | 0.0% | n/c | 1 | SEC ↗ |
| 53 | Jones Financial Companies Lllp | 40.40K | — | $140,198 | 0.0% | n/c | 1 | SEC ↗ |
| 54 | Mariner, LLC | 36.29K | — | $125,925 | 0.0% | n/c | 1 | SEC ↗ |
| 55 | Commonwealth Equity Services, Llc | 34.40K | — | $119,360 | 0.0% | n/c | 1 | SEC ↗ |
| 56 | LPL Financial LLC | 32.92K | — | $114,246 | 0.0% | n/c | 1 | SEC ↗ |
| 57 | Envestnet Asset Management Inc | 32.58K | — | $113,039 | 0.0% | n/c | 1 | SEC ↗ |
| 58 | Manufacturers Life Insurance… | 31.60K | — | $109,659 | 0.0% | n/c | 1 | SEC ↗ |
| 59 | Wealth Enhancement Advisory… | 26.10K | — | $96,563 | 0.0% | n/c | 1 | SEC ↗ |
| 60 | Raymond James Financial Inc | 27.04K | — | $93,842 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 61 | ProShare Advisors LLC | 26.16K | — | $90,769 | 0.0% | n/c | 1 | SEC ↗ |
| 62 | Cwm, Llc | 25.43K | — | $88,000 | 0.0% | n/c | 1 | SEC ↗ |
| 63 | Nomura Holdings Inc | 24.79K | — | $86,018 | 0.0% | n/c | 1 | SEC ↗ |
| 64 | Creative Planning | 17.89K | — | $62,085 | 0.0% | n/c | 1 | SEC ↗ |
| 65 | Voya Investment Management Llc | 17.49K | — | $60,694 | 0.0% | n/c | 1 | SEC ↗ |
| 66 | Neuberger Berman Group LLC | 10.91K | — | $37,875 | 0.0% | n/c | 1 | SEC ↗ |
| 67 | Lazard Asset Management Llc | 10.84K | — | $37,629 | 0.0% | n/c | 1 | SEC ↗ |
| 68 | Victory Capital Management Inc | 10.80K | — | $37,479 | 0.0% | n/c | 1 | SEC ↗ |
| 69 | Bnp Paribas Financial Markets | 9.82K | — | $34,086 | 0.0% | n/c | 1 | SEC ↗ |
| 70 | Zurcher Kantonalbank (Zurich… | 8.81K | — | $30,585 | 0.0% | n/c | 1 | SEC ↗ |
| 71 | Mirae Asset Global Investments Co.… | 8.77K | — | $30,439 | 0.0% | n/c | 1 | SEC ↗ |
| 72 | New York State Common Retirement… | 8.43K | — | $29,266 | 0.0% | n/c | 1 | SEC ↗ |
| 73 | Osaic Holdings, Inc. | 8.43K | — | $29,243 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 74 | Russell Investments Group, Ltd. | 6.83K | — | $23,690 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 75 | Royal Bank Of Canada | 4.89K | — | $17,000 | 0.0% | n/c | 1 | SEC ↗ ×4 |
| 76 | Pnc Financial Services Group, Inc. | 319 | — | $1,107 | 0.0% | n/c | 1 | SEC ↗ |
| 77 | Daiwa Securities Group Inc. | 398 | — | $1,000 | 0.0% | n/c | 1 | SEC ↗ |
| 78 | Optiver Holding B.V. | 160 | — | $555 | 0.0% | n/c | 1 | SEC ↗ |
“Their weight” = the position's share of that manager's reported 13F equity value — the conviction measure. ✦ = curated manager.
New buyers
| Point72 Asset Management | $1.91M | 0.0% |
Exited
| Adage Capital Partners | $4.27M | was 0.0% |
Full-market context: across ALL 13F filers (SEC structured data, Q1 2026): 189 holders, 97.53M shares, $314.58M reported. This is a different, older period than the tracked-universe figures above and the two are never mixed.
Frequently co-owned
What else this security's tracked holders most often hold — shared-ownership counts, not fundamental relationships.
Provenance: Ownership from parsed 13F common-stock positions (tracked universe, comparable sets for changes); insider rows from Forms 3/4/5; stakes from Schedules 13D/13G; every filing links to its original on SEC EDGAR.
Reporting period: Q4 2025 ·
Methodology ·
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