Security record · archived quarter
PRME
Prime Medicine, Inc. · Healthcare · Biotechnology
18Tracked holders
+3Δ holders
30.74MShares held
$170.29MReported value
+3New positions
−0Exits
Momentum inputs (comparable managers):
holder breadth +20.0% ·
share flow +30.0% ·
net new positions +16.7%
— formula
Broad accumulation — rising shares across more holders
All ownership figures: tracked 13F managers only, common-stock positions, reporting period Q3 2025
Ownership over time
| Quarter | Holders | Δ | Shares | Reported value | New | Exits |
|---|---|---|---|---|---|---|
| Q2 2026 | 78 | +1 | 62.51M | $230.64M | +6 | −5 |
| Q1 2026 | 80 | +2 | 55.31M | $192.04M | +9 | −7 |
| Q4 2025 | 78 | 0 | 56.37M | $195.61M | +1 | −1 |
| Q3 2025 | 18 | +3 | 30.74M | $170.29M | +3 | — |
| Q2 2025 | 12 | +1 | 18.57M | $45.87M | +1 | — |
| Q1 2025 | 8 | 0 | 10.06M | $20.03M | +1 | −1 |
| Q4 2024 | 8 | -1 | 11.48M | $33.53M | +2 | −3 |
| Q3 2024 | 8 | -1 | 11.29M | $43.71M | +1 | −2 |
| Q2 2024 | 9 | — | 11.11M | $57.12M | — | — |
Who holds it · Q3 2025
| # | Manager | Shares | Δ shares | Value | Their weight | Held | ||
|---|---|---|---|---|---|---|---|---|
| 1 | BlackRock ✦ (passive) | 5.65M | +26.0% | $31.31M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 2 | BlackRock ✦ (passive) | 5.65M | +26.0% | $31.31M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 3 | BlackRock ✦ (passive) | 5.65M | +26.0% | $31.31M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 4 | BlackRock ✦ (passive) | 5.65M | +26.0% | $31.31M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 5 | BlackRock ✦ (passive) | 5.65M | +26.0% | $31.31M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 6 | BlackRock ✦ (passive) | 5.65M | +26.0% | $31.31M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 7 | BlackRock ✦ (passive) | 5.65M | +26.0% | $31.31M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 8 | BlackRock ✦ (passive) | 5.65M | +26.0% | $31.31M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 9 | ARK Investment Management ✦ | 5.48M | +135.8% | $30.35M | 0.2% | ▲ Add | 6 | SEC ↗ |
| 10 | The Vanguard Group ✦ (passive) | 4.92M | +35.7% | $27.27M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 11 | The Vanguard Group ✦ (passive) | 4.92M | +35.7% | $27.27M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 12 | The Vanguard Group ✦ (passive) | 4.92M | +35.7% | $27.27M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 13 | Fidelity (FMR) ✦ | 2.81M | -24.9% | $15.58M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 14 | Fidelity (FMR) ✦ | 2.81M | -24.9% | $15.58M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 15 | Fidelity (FMR) ✦ | 2.81M | -24.9% | $15.58M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 16 | D. E. Shaw & Co. ✦ | 2.22M | New | $12.28M | 0.0% | New | 1 | SEC ↗ |
| 17 | Geode Capital Management ✦ (passive) | 1.77M | +16.9% | $9.79M | 0.0% | ▲ Add | 6 | SEC ↗ |
| 18 | Geode Capital Management ✦ (passive) | 1.77M | +16.9% | $9.79M | 0.0% | ▲ Add | 6 | SEC ↗ |
| 19 | Millennium Management ✦ | 1.42M | +858.5% | $7.86M | 0.0% | ▲ Add | 6 | SEC ↗ |
| 20 | State Street Global Advisors ✦ (passive) | 1.30M | +4.6% | $7.18M | 0.0% | ▲ Add | 4 | SEC ↗ |
| 21 | Renaissance Technologies ✦ | 1.13M | +407.9% | $6.29M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 22 | Citadel Advisors ✦ | 900.14K | +72.6% | $4.99M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 23 | Citadel Advisors ✦ | 900.14K | +72.6% | $4.99M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 24 | Adage Capital Partners ✦ | 771.36K | New | $4.27M | 0.0% | New | 1 | SEC ↗ |
| 25 | Morgan Stanley ✦ | 731.00K | — | $4.05M | 0.0% | n/c | 1 | SEC ↗ |
| 26 | Morgan Stanley ✦ | 731.00K | — | $4.05M | 0.0% | n/c | 1 | SEC ↗ |
| 27 | Morgan Stanley ✦ | 731.00K | — | $4.05M | 0.0% | n/c | 1 | SEC ↗ |
| 28 | Morgan Stanley ✦ | 731.00K | — | $4.05M | 0.0% | n/c | 1 | SEC ↗ |
| 29 | Morgan Stanley ✦ | 731.00K | — | $4.05M | 0.0% | n/c | 1 | SEC ↗ |
| 30 | Morgan Stanley ✦ | 731.00K | — | $4.05M | 0.0% | n/c | 1 | SEC ↗ |
| 31 | Two Sigma Investments ✦ | 447.67K | +73.2% | $2.48M | 0.0% | ▲ Add | 6 | SEC ↗ |
| 32 | AQR Capital Management ✦ | 414.21K | -2.4% | $2.29M | 0.0% | ▼ Trim | 4 | SEC ↗ |
| 33 | AQR Capital Management ✦ | 414.21K | -2.4% | $2.29M | 0.0% | ▼ Trim | 4 | SEC ↗ |
| 34 | AQR Capital Management ✦ | 414.21K | -2.4% | $2.29M | 0.0% | ▼ Trim | 4 | SEC ↗ |
| 35 | AQR Capital Management ✦ | 414.21K | -2.4% | $2.29M | 0.0% | ▼ Trim | 4 | SEC ↗ |
| 36 | Goldman Sachs Group ✦ | 410.74K | — | $2.28M | 0.0% | n/c | 1 | SEC ↗ |
| 37 | Goldman Sachs Group ✦ | 410.74K | — | $2.28M | 0.0% | n/c | 1 | SEC ↗ |
| 38 | Wellington Management ✦ | 205.32K | New | $1.14M | 0.0% | New | 1 | SEC ↗ |
| 39 | Wellington Management ✦ | 205.32K | New | $1.14M | 0.0% | New | 1 | SEC ↗ |
| 40 | Wellington Management ✦ | 205.32K | New | $1.14M | 0.0% | New | 1 | SEC ↗ |
| 41 | JPMorgan Chase ✦ | 86.78K | — | $480,750 | 0.0% | n/c | 1 | SEC ↗ |
| 42 | JPMorgan Chase ✦ | 86.78K | — | $480,750 | 0.0% | n/c | 1 | SEC ↗ |
| 43 | JPMorgan Chase ✦ | 86.78K | — | $480,750 | 0.0% | n/c | 1 | SEC ↗ |
| 44 | JPMorgan Chase ✦ | 86.78K | — | $480,750 | 0.0% | n/c | 1 | SEC ↗ |
| 45 | T. Rowe Price ✦ | 74.50K | +14.1% | $413,000 | 0.0% | ▲ Add | 6 | SEC ↗ |
“Their weight” = the position's share of that manager's reported 13F equity value — the conviction measure. ✦ = curated manager.
New buyers
| D. E. Shaw & Co. | $12.28M | 0.0% |
| Adage Capital Partners | $4.27M | 0.0% |
| Wellington Management | $1.14M | 0.0% |
| Wellington Management | $1.14M | 0.0% |
| Wellington Management | $1.14M | 0.0% |
Exited
| No tracked exits this quarter. |
Full-market context: across ALL 13F filers (SEC structured data, Q1 2026): 189 holders, 97.53M shares, $314.58M reported. This is a different, older period than the tracked-universe figures above and the two are never mixed.
Frequently co-owned
What else this security's tracked holders most often hold — shared-ownership counts, not fundamental relationships.
Provenance: Ownership from parsed 13F common-stock positions (tracked universe, comparable sets for changes); insider rows from Forms 3/4/5; stakes from Schedules 13D/13G; every filing links to its original on SEC EDGAR.
Reporting period: Q3 2025 ·
Methodology ·
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