PRME
Prime Medicine, Inc. · Healthcare · Biotechnology
Momentum inputs (comparable managers):
holder breadth -11.1% ·
share flow -7.8% ·
net new positions -12.5%
— formula
Broad distribution — falling shares and fewer holders
All ownership figures: tracked 13F managers only, common-stock positions, reporting period Q4 2024
| Quarter | Holders | Δ | Shares | Reported value | New | Exits |
|---|---|---|---|---|---|---|
| Q2 2026 | 78 | +1 | 62.51M | $230.64M | +6 | −5 |
| Q1 2026 | 80 | +2 | 55.31M | $192.04M | +9 | −7 |
| Q4 2025 | 78 | 0 | 56.37M | $195.61M | +1 | −1 |
| Q3 2025 | 18 | +3 | 30.74M | $170.29M | +3 | — |
| Q2 2025 | 12 | +1 | 18.57M | $45.87M | +1 | — |
| Q1 2025 | 8 | 0 | 10.06M | $20.03M | +1 | −1 |
| Q4 2024 | 8 | -1 | 11.48M | $33.53M | +2 | −3 |
| Q3 2024 | 8 | -1 | 11.29M | $43.71M | +1 | −2 |
| Q2 2024 | 9 | — | 11.11M | $57.12M | — | — |
| # | Manager | Shares | Δ shares | Value | Their weight | Held | ||
|---|---|---|---|---|---|---|---|---|
| 1 | ARK Investment Management ✦ | 5.15M | -9.0% | $15.04M | 0.1% | ▼ Trim | 3 | SEC ↗ |
| 2 | Millennium Management ✦ | 1.87M | -14.7% | $5.47M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 3 | T. Rowe Price ✦ | 1.58M | +2.5% | $4.63M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 4 | T. Rowe Price ✦ | 1.58M | +2.5% | $4.63M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 5 | Geode Capital Management ✦ (passive) | 1.47M | +7.9% | $4.29M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 6 | Geode Capital Management ✦ (passive) | 1.47M | +7.9% | $4.29M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 7 | State Street Global Advisors ✦ (passive) | 1.15M | — | $3.37M | 0.0% | n/c | 1 | SEC ↗ |
| 8 | Two Sigma Investments ✦ | 166.20K | -47.8% | $485,301 | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 9 | Point72 Asset Management ✦ | 68.53K | New | $200,102 | 0.0% | New | 1 | SEC ↗ |
| 10 | AQR Capital Management ✦ | 16.05K | New | $46,854 | 0.0% | New | 1 | SEC ↗ |
| 11 | AQR Capital Management ✦ | 16.05K | New | $46,854 | 0.0% | New | 1 | SEC ↗ |
| 12 | AQR Capital Management ✦ | 16.05K | New | $46,854 | 0.0% | New | 1 | SEC ↗ |
“Their weight” = the position's share of that manager's reported 13F equity value — the conviction measure. ✦ = curated manager.
New buyers
| Point72 Asset Management | $200,102 | 0.0% |
| AQR Capital Management | $46,854 | 0.0% |
| AQR Capital Management | $46,854 | 0.0% |
| AQR Capital Management | $46,854 | 0.0% |
Exited
| D. E. Shaw & Co. | $539,675 | was 0.0% |
| Citadel Advisors | $197,351 | was 0.0% |
| Renaissance Technologies | $77,400 | was 0.0% |
Full-market context: across ALL 13F filers (SEC structured data, Q1 2026): 189 holders, 97.53M shares, $314.58M reported. This is a different, older period than the tracked-universe figures above and the two are never mixed.
What else this security's tracked holders most often hold — shared-ownership counts, not fundamental relationships.