Security record · archived quarter
PRAX
Praxis Precision Medicines, Inc. · Healthcare · Biotechnology
101Tracked holders
+1Δ holders
18.04MShares held
$5.32BReported value
+2New positions
−0Exits
Momentum inputs (comparable managers):
holder breadth +1.0% ·
share flow -0.8% ·
net new positions +2.0%
· formula
Ownership fragmentation: more holders, smaller aggregate stake
All ownership figures: tracked 13F managers only, common-stock positions, reporting period Q4 2025
Ownership over time
| Quarter | Holders | Δ | Shares | Reported value | New | Exits |
|---|---|---|---|---|---|---|
| Q3 2026 | 1 | 0 | 905 | $238,513 | n/a | n/a |
| Q2 2026 | 110 | +10 | 16.58M | $5.55B | +16 | −6 |
| Q1 2026 | 103 | +2 | 17.55M | $5.65B | +11 | −10 |
| Q4 2025 | 101 | +1 | 18.04M | $5.32B | +2 | n/a |
| Q3 2025 | 17 | +1 | 10.82M | $573.60M | +1 | −1 |
| Q2 2025 | 14 | 0 | 8.51M | $357.72M | +1 | −1 |
| Q1 2025 | 11 | -2 | 4.62M | $175.13M | n/a | −2 |
| Q4 2024 | 13 | 0 | 4.07M | $313.25M | n/a | n/a |
| Q3 2024 | 12 | 0 | 3.95M | $227.16M | +1 | −1 |
| Q2 2024 | 12 | n/a | 4.09M | $168.97M | n/a | n/a |
Who holds it · Q4 2025
| # | Manager | Shares | Δ shares | Value | Their weight | Held | ||
|---|---|---|---|---|---|---|---|---|
| 1 | Janus Henderson Group Plc | 3.24M | n/a | $954.83M | 0.4% | n/c | 1 | SEC ↗ ×3 |
| 2 | BlackRock ✦ (passive) | 2.08M | +15.4% | $612.62M | 0.0% | ▲ Add | 3 | SEC ↗ ×16 |
| 3 | The Vanguard Group ✦ (passive) | 1.46M | +15.3% | $430.60M | 0.0% | ▲ Add | 3 | SEC ↗ ×5 |
| 4 | Fidelity (FMR) ✦ | 1.36M | +3044.3% | $400.46M | 0.0% | ▲ Add | 3 | SEC ↗ ×5 |
| 5 | Adage Capital Partners ✦ | 965.31K | -59.3% | $284.52M | 0.4% | ▼ Trim | 7 | SEC ↗ |
| 6 | Morgan Stanley ✦ | 889.89K | +38.3% | $262.29M | 0.0% | ▲ Add | 2 | SEC ↗ ×6 |
| 7 | State Street Global Advisors ✦ (passive) | 882.22K | -2.7% | $260.02M | 0.0% | ▼ Trim | 5 | SEC ↗ |
| 8 | T. Rowe Price ✦ | 785.99K | -21.7% | $231.66M | 0.0% | ▼ Trim | 7 | SEC ↗ ×2 |
| 9 | Goldman Sachs Group ✦ | 716.18K | +20.8% | $211.09M | 0.0% | ▲ Add | 2 | SEC ↗ ×4 |
| 10 | Geode Capital Management ✦ (passive) | 562.38K | +23.1% | $165.78M | 0.0% | ▲ Add | 7 | SEC ↗ ×2 |
| 11 | Barclays Plc | 530.75K | n/a | $156.43M | 0.1% | n/c | 1 | SEC ↗ ×3 |
| 12 | Bank Of America Corp /De/ | 522.76K | n/a | $154.08M | 0.0% | n/c | 1 | SEC ↗ ×6 |
| 13 | Point72 Asset Management ✦ | 492.35K | -67.1% | $145.11M | 0.2% | ▼ Trim | 7 | SEC ↗ |
| 14 | Assenagon Asset Management S.A. | 408.79K | n/a | $120.49M | 0.2% | n/c | 1 | SEC ↗ |
| 15 | Franklin Resources Inc | 356.07K | n/a | $104.95M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 16 | Pictet Asset Management Holding SA | 240.59K | n/a | $71.09M | 0.1% | n/c | 1 | SEC ↗ |
| 17 | Charles Schwab Investment… | 198.30K | n/a | $58.45M | 0.0% | n/c | 1 | SEC ↗ |
| 18 | Northern Trust Corp | 192.28K | n/a | $56.67M | 0.0% | n/c | 1 | SEC ↗ ×6 |
| 19 | Wellington Management ✦ | 176.56K | +188.3% | $52.04M | 0.0% | ▲ Add | 7 | SEC ↗ ×7 |
| 20 | Qube Research & Technologies Ltd | 168.90K | n/a | $49.78M | 0.1% | n/c | 1 | SEC ↗ |
| 21 | Aberdeen Group plc | 134.99K | n/a | $39.79M | 0.1% | n/c | 1 | SEC ↗ |
| 22 | UBS Group AG | 89.20K | n/a | $26.29M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 23 | First Trust Advisors Lp | 88.70K | n/a | $26.14M | 0.0% | n/c | 1 | SEC ↗ |
| 24 | Bank of New York Mellon Corp | 77.90K | n/a | $22.96M | 0.0% | n/c | 1 | SEC ↗ ×6 |
| 25 | Invesco Ltd. | 77.09K | n/a | $22.72M | 0.0% | n/c | 1 | SEC ↗ ×4 |
| 26 | American Century Companies Inc | 75.37K | n/a | $22.21M | 0.0% | n/c | 1 | SEC ↗ |
| 27 | Alyeska Investment Group, L.P. | 74.38K | n/a | $21.92M | 0.1% | n/c | 1 | SEC ↗ |
| 28 | Canada Pension Plan Investment Board | 69.71K | n/a | $20.55M | 0.0% | n/c | 1 | SEC ↗ |
| 29 | Marshall Wace ✦ | 69.24K | +1.6% | $20.41M | 0.0% | ▲ Add | 2 | SEC ↗ ×2 |
| 30 | Renaissance Technologies ✦ | 66.23K | New | $19.52M | 0.0% | New | 1 | SEC ↗ |
| 31 | Ensign Peak Advisors, Inc | 64.28K | n/a | $18.95M | 0.0% | n/c | 1 | SEC ↗ |
| 32 | JPMorgan Chase ✦ | 55.30K | +5.5% | $16.30M | 0.0% | ▲ Add | 2 | SEC ↗ ×7 |
| 33 | Deutsche Bank Ag\ | 50.81K | n/a | $14.98M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 34 | Nuveen, LLC | 49.97K | n/a | $14.73M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 35 | Td Asset Management Inc | 46.15K | n/a | $13.60M | 0.0% | n/c | 1 | SEC ↗ |
| 36 | Swiss National Bank | 40.50K | n/a | $11.94M | 0.0% | n/c | 1 | SEC ↗ |
| 37 | D. E. Shaw & Co. ✦ | 37.48K | +89.3% | $11.05M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 38 | Universal- Beteiligungs- und… | 37.38K | n/a | $11.02M | 0.0% | n/c | 1 | SEC ↗ |
| 39 | UBS AM, a distinct business unit of… | 35.29K | n/a | $10.40M | 0.0% | n/c | 1 | SEC ↗ ×8 |
| 40 | Citadel Advisors ✦ | 34.92K | +347.8% | $10.29M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 41 | Manufacturers Life Insurance… | 33.29K | n/a | $9.86M | 0.0% | n/c | 1 | SEC ↗ |
| 42 | AQR Capital Management ✦ | 28.83K | +31.6% | $8.50M | 0.0% | ▲ Add | 3 | SEC ↗ ×6 |
| 43 | Rhumbline Advisers | 28.32K | n/a | $8.35M | 0.0% | n/c | 1 | SEC ↗ |
| 44 | Neuberger Berman Group LLC | 25.68K | n/a | $7.57M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 45 | MIRAE ASSET GLOBAL ETFS HOLDINGS… | 25.56K | n/a | $7.54M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 46 | Wells Fargo & Company/Mn | 25.23K | n/a | $7.44M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 47 | Alliancebernstein L.P. | 25.07K | n/a | $7.39M | 0.0% | n/c | 1 | SEC ↗ |
| 48 | Dimensional Fund Advisors Lp | 23.54K | n/a | $6.94M | 0.0% | n/c | 1 | SEC ↗ |
| 49 | Two Sigma Investments ✦ | 23.10K | +319.4% | $6.81M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 50 | Ameriprise Financial Inc | 22.71K | n/a | $6.70M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 51 | Man Group plc | 21.17K | n/a | $6.24M | 0.0% | n/c | 1 | SEC ↗ |
| 52 | Russell Investments Group, Ltd. | 20.61K | n/a | $6.08M | 0.0% | n/c | 1 | SEC ↗ ×6 |
| 53 | California State Teachers… | 19.67K | n/a | $5.80M | 0.0% | n/c | 1 | SEC ↗ |
| 54 | Legal & General Group Plc | 17.98K | n/a | $5.30M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 55 | Tudor Investment Corp Et Al | 16.01K | n/a | $4.72M | 0.0% | n/c | 1 | SEC ↗ |
| 56 | Sei Investments Co | 15.80K | n/a | $4.66M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 57 | State Of Wisconsin Investment Board | 15.23K | n/a | $4.49M | 0.0% | n/c | 1 | SEC ↗ |
| 58 | Prudential Financial Inc | 14.86K | n/a | $4.38M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 59 | Voya Investment Management Llc | 13.65K | n/a | $4.02M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 60 | Victory Capital Management Inc | 13.30K | n/a | $3.92M | 0.0% | n/c | 1 | SEC ↗ |
| 61 | Creative Planning | 10.84K | n/a | $3.20M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 62 | New York State Common Retirement… | 7.30K | n/a | $2.15M | 0.0% | n/c | 1 | SEC ↗ |
| 63 | Connor, Clark & Lunn Investment… | 6.87K | n/a | $2.02M | 0.0% | n/c | 1 | SEC ↗ |
| 64 | State Board Of Administration Of… | 5.81K | n/a | $1.71M | 0.0% | n/c | 1 | SEC ↗ |
| 65 | Citigroup Inc | 5.59K | n/a | $1.65M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 66 | Envestnet Asset Management Inc | 5.55K | n/a | $1.64M | 0.0% | n/c | 1 | SEC ↗ |
| 67 | Group One Trading Llc | 5.54K | n/a | $1.63M | 0.0% | n/c | 1 | SEC ↗ |
| 68 | Raymond James Financial Inc | 5.24K | n/a | $1.54M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 69 | ProShare Advisors LLC | 5.21K | n/a | $1.54M | 0.0% | n/c | 1 | SEC ↗ |
| 70 | Bnp Paribas Financial Markets | 4.63K | n/a | $1.36M | 0.0% | n/c | 1 | SEC ↗ |
| 71 | Healthcare Of Ontario Pension Plan… | 4.59K | n/a | $1.35M | 0.0% | n/c | 1 | SEC ↗ |
| 72 | Norges Bank ✦ (passive) | 4.35K | New | $1.28M | 0.0% | New | 1 | SEC ↗ |
| 73 | Cerity Partners LLC | 3.93K | n/a | $1.16M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 74 | Royal Bank Of Canada | 3.38K | n/a | $995,000 | 0.0% | n/c | 1 | SEC ↗ ×4 |
| 75 | Massachusetts Financial Services Co… | 3.32K | n/a | $977,358 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 76 | Quantinno Capital Management LP | 2.72K | n/a | $802,577 | 0.0% | n/c | 1 | SEC ↗ |
| 77 | Allianz Asset Management GmbH | 2.40K | n/a | $707,376 | 0.0% | n/c | 1 | SEC ↗ |
| 78 | Susquehanna International Group, Llp | 2.34K | n/a | $690,576 | 0.0% | n/c | 1 | SEC ↗ |
| 79 | Squarepoint Ops LLC | 1.89K | n/a | $557,059 | 0.0% | n/c | 1 | SEC ↗ |
| 80 | Us Bancorp \De\ | 1.82K | n/a | $537,901 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 81 | Allspring Global Investments… | 1.73K | n/a | $496,045 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 82 | Hsbc Holdings Plc | 1.65K | n/a | $488,764 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 83 | Mackenzie Financial Corp | 1.40K | n/a | $414,713 | 0.0% | n/c | 1 | SEC ↗ |
| 84 | Mirae Asset Global Investments Co.… | 1.22K | n/a | $358,109 | 0.0% | n/c | 1 | SEC ↗ |
| 85 | Mercer Global Advisors Inc /Adv | 1.21K | n/a | $357,224 | 0.0% | n/c | 1 | SEC ↗ |
| 86 | Principal Financial Group Inc | 995 | n/a | $293,266 | 0.0% | n/c | 1 | SEC ↗ |
| 87 | CIBC Asset Management Inc | 900 | n/a | $265,266 | 0.0% | n/c | 1 | SEC ↗ |
| 88 | Cwm, Llc | 874 | n/a | $258,000 | 0.0% | n/c | 1 | SEC ↗ |
| 89 | Mml Investors Services, Llc | 864 | n/a | $254,655 | 0.0% | n/c | 1 | SEC ↗ |
| 90 | Amundi | 790 | n/a | $232,845 | 0.0% | n/c | 1 | SEC ↗ |
| 91 | Commonwealth Equity Services, Llc | 745 | n/a | $219,580 | 0.0% | n/c | 1 | SEC ↗ |
| 92 | Pnc Financial Services Group, Inc. | 714 | n/a | $210,445 | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 93 | BNP Paribas Asset Management… | 279 | n/a | $82,000 | 0.0% | n/c | 1 | SEC ↗ |
| 94 | Danske Bank A/S | 200 | n/a | $58,948 | 0.0% | n/c | 1 | SEC ↗ |
| 95 | Zurcher Kantonalbank (Zurich… | 98 | n/a | $28,885 | 0.0% | n/c | 1 | SEC ↗ |
| 96 | Osaic Holdings, Inc. | 83 | n/a | $24,462 | 0.0% | n/c | 1 | SEC ↗ |
| 97 | Daiwa Securities Group Inc. | 72 | n/a | $21,000 | 0.0% | n/c | 1 | SEC ↗ |
| 98 | Rockefeller Capital Management L.P. | 64 | n/a | $18,863 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 99 | Optiver Holding B.V. | 60 | n/a | $17,684 | 0.0% | n/c | 1 | SEC ↗ |
| 100 | Federated Hermes, Inc. | 44 | n/a | $12,969 | 0.0% | n/c | 1 | SEC ↗ |
“Their weight” = the position's share of that manager's reported 13F equity value: the conviction measure. ✦ = curated manager.
New buyers
| Renaissance Technologies | $19.52M | 0.0% |
| Norges Bank | $1.28M | 0.0% |
Exited
| No tracked exits this quarter. |
Full-market context: across ALL 13F filers (SEC structured data, Q1 2026): 287 holders, 28.34M shares, $8.85B reported. This is a different, older period than the tracked-universe figures above and the two are never mixed.
Frequently co-owned
What else this security's tracked holders most often hold: shared-ownership counts, not fundamental relationships.
Provenance: Ownership from parsed 13F common-stock positions (tracked universe, comparable sets for changes); insider rows from Forms 3/4/5; stakes from Schedules 13D/13G; every filing links to its original on SEC EDGAR.
Reporting period: Q4 2025 ·
Methodology ·
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