Security record · archived quarter
MLYS
Mineralys Therapeutics, Inc. · Healthcare · Biotechnology
87Tracked holders
+2Δ holders
39.40MShares held
$1.08BReported value
+7New positions
−5Exits
Momentum inputs (comparable managers):
holder breadth +2.4% ·
share flow -1.2% ·
net new positions +2.3%
· formula
Ownership fragmentation: more holders, smaller aggregate stake
All ownership figures: tracked 13F managers only, common-stock positions, reporting period Q1 2026
Ownership over time
| Quarter | Holders | Δ | Shares | Reported value | New | Exits |
|---|---|---|---|---|---|---|
| Q2 2026 | 86 | +2 | 43.69M | $1.18B | +8 | −6 |
| Q1 2026 | 87 | +2 | 39.40M | $1.08B | +7 | −5 |
| Q4 2025 | 84 | +1 | 40.64M | $1.47B | +2 | −1 |
| Q3 2025 | 17 | +2 | 19.50M | $739.53M | +2 | n/a |
| Q2 2025 | 12 | -1 | 9.30M | $125.82M | n/a | −1 |
| Q1 2025 | 10 | +4 | 2.76M | $43.90M | +4 | n/a |
| Q4 2024 | 6 | 0 | 2.45M | $30.15M | +1 | −1 |
| Q3 2024 | 5 | 0 | 890.52K | $10.79M | +1 | −1 |
| Q2 2024 | 5 | n/a | 738.83K | $8.65M | n/a | n/a |
Who holds it · Q1 2026
| # | Manager | Shares | Δ shares | Value | Their weight | Held | ||
|---|---|---|---|---|---|---|---|---|
| 1 | Fidelity (FMR) ✦ | 4.86M | -3.9% | $131.69M | 0.0% | ▼ Trim | 4 | SEC ↗ ×4 |
| 2 | BlackRock ✦ (passive) | 4.48M | +3.6% | $121.41M | 0.0% | ▲ Add | 4 | SEC ↗ ×14 |
| 3 | Wellington Management ✦ | 3.36M | +328.3% | $91.00M | 0.0% | ▲ Add | 7 | SEC ↗ ×7 |
| 4 | State Street Global Advisors ✦ (passive) | 2.94M | -7.8% | $79.53M | 0.0% | ▼ Trim | 6 | SEC ↗ |
| 5 | Vanguard Capital Management Llc | 2.45M | n/a | $66.49M | 0.0% | n/c | 1 | SEC ↗ |
| 6 | Point72 Asset Management ✦ | 1.91M | +58.3% | $51.78M | 0.1% | ▲ Add | 3 | SEC ↗ |
| 7 | Franklin Resources Inc | 1.78M | -0.2% | $48.35M | 0.0% | ▼ Trim | 2 | SEC ↗ ×4 |
| 8 | T. Rowe Price ✦ | 1.34M | +1.4% | $36.39M | 0.0% | ▲ Add | 6 | SEC ↗ ×2 |
| 9 | Alliancebernstein L.P. | 975.96K | +5.8% | $35.42M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 10 | Geode Capital Management ✦ (passive) | 1.30M | +3.5% | $35.25M | 0.0% | ▲ Add | 8 | SEC ↗ ×2 |
| 11 | Jennison Associates Llc | 1.27M | +0.6% | $34.30M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 12 | Bank Of America Corp /De/ | 1.10M | +11.4% | $29.81M | 0.0% | ▲ Add | 2 | SEC ↗ ×3 |
| 13 | Pictet Asset Management Holding SA | 1.03M | +21.3% | $28.02M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 14 | Qube Research & Technologies Ltd | 914.73K | +84.2% | $24.78M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 15 | D. E. Shaw & Co. ✦ | 887.19K | -22.9% | $24.03M | 0.0% | ▼ Trim | 5 | SEC ↗ ×2 |
| 16 | American Century Companies Inc | 884.11K | -2.6% | $23.95M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 17 | Morgan Stanley ✦ | 849.18K | +32.8% | $23.00M | 0.0% | ▲ Add | 3 | SEC ↗ ×8 |
| 18 | Goldman Sachs Group ✦ | 785.04K | -45.9% | $21.27M | 0.0% | ▼ Trim | 3 | SEC ↗ ×2 |
| 19 | Citadel Advisors ✦ | 600.04K | +50.0% | $16.26M | 0.0% | ▲ Add | 5 | SEC ↗ ×2 |
| 20 | Millennium Management ✦ | 525.26K | +568.1% | $14.23M | 0.0% | ▲ Add | 8 | SEC ↗ |
| 21 | Charles Schwab Investment… | 443.90K | -3.8% | $12.03M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 22 | Northern Trust Corp | 442.87K | +47.7% | $12.00M | 0.0% | ▲ Add | 2 | SEC ↗ ×5 |
| 23 | Capital World Investors ✦ | 398.18K | New | $10.79M | 0.0% | New | 1 | SEC ↗ |
| 24 | Renaissance Technologies ✦ | 382.80K | +18.9% | $10.37M | 0.0% | ▲ Add | 8 | SEC ↗ |
| 25 | Two Sigma Investments ✦ | 311.49K | -49.0% | $8.44M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 26 | Ameriprise Financial Inc | 221.31K | +378.5% | $6.00M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 27 | Voya Investment Management Llc | 216.09K | +91.8% | $5.85M | 0.0% | ▲ Add | 2 | SEC ↗ ×3 |
| 28 | Russell Investments Group, Ltd. | 203.50K | +16.1% | $5.51M | 0.0% | ▲ Add | 2 | SEC ↗ ×6 |
| 29 | Tudor Investment Corp Et Al | 155.74K | +298.9% | $4.22M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 30 | AQR Capital Management ✦ | 149.09K | +139.3% | $4.04M | 0.0% | ▲ Add | 5 | SEC ↗ ×7 |
| 31 | Dimensional Fund Advisors Lp | 137.43K | -0.1% | $3.72M | 0.0% | ▼ Trim | 2 | SEC ↗ ×4 |
| 32 | Bank of New York Mellon Corp | 129.96K | -1.4% | $3.52M | 0.0% | ▼ Trim | 2 | SEC ↗ ×6 |
| 33 | Swedbank AB | 122.10K | -44.9% | $3.31M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 34 | Schroder Investment Management Group | 130.59K | n/a | $3.07M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 35 | Ensign Peak Advisors, Inc | 112.19K | 0.0% | $3.04M | 0.0% | Held | 2 | SEC ↗ |
| 36 | Nuveen, LLC | 112.01K | -8.9% | $3.03M | 0.0% | ▼ Trim | 2 | SEC ↗ ×2 |
| 37 | Squarepoint Ops LLC | 105.49K | -57.3% | $2.86M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 38 | UBS Group AG | 98.03K | -51.3% | $2.66M | 0.0% | ▼ Trim | 2 | SEC ↗ ×3 |
| 39 | Hrt Financial Lp | 95.92K | +9.9% | $2.60M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 40 | Swiss National Bank | 90.10K | 0.0% | $2.44M | 0.0% | Held | 2 | SEC ↗ |
| 41 | UBS AM, a distinct business unit of… | 79.54K | +4.8% | $2.15M | 0.0% | ▲ Add | 2 | SEC ↗ ×6 |
| 42 | State Of Wisconsin Investment Board | 64.14K | +28.4% | $1.74M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 43 | California State Teachers… | 61.27K | +41.3% | $1.66M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 44 | Prudential Financial Inc | 59.55K | -33.1% | $1.61M | 0.0% | ▼ Trim | 2 | SEC ↗ ×2 |
| 45 | DZ BANK AG Deutsche Zentral… | 59.24K | -47.0% | $1.60M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 46 | Rhumbline Advisers | 57.44K | +5.8% | $1.56M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 47 | Canada Pension Plan Investment Board | 51.40K | +73.7% | $1.39M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 48 | JPMorgan Chase ✦ | 51.92K | +11.2% | $1.22M | 0.0% | ▲ Add | 3 | SEC ↗ ×5 |
| 49 | Invesco Ltd. | 42.31K | +45.2% | $1.15M | 0.0% | ▲ Add | 2 | SEC ↗ ×4 |
| 50 | Deutsche Bank Ag\ | 40.12K | +7.7% | $1.09M | 0.0% | ▲ Add | 2 | SEC ↗ ×2 |
| 51 | Legal & General Group Plc | 38.47K | -12.4% | $1.04M | 0.0% | ▼ Trim | 2 | SEC ↗ ×3 |
| 52 | Barclays Plc | 33.88K | -84.8% | $917,726 | 0.0% | ▼ Trim | 2 | SEC ↗ ×3 |
| 53 | Victory Capital Management Inc | 33.14K | +0.8% | $897,790 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 54 | MIRAE ASSET GLOBAL ETFS HOLDINGS… | 29.18K | 0.0% | $766,686 | 0.0% | ▲ Add | 2 | SEC ↗ ×2 |
| 55 | Manufacturers Life Insurance… | 26.41K | +63.2% | $715,474 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 56 | Wells Fargo & Company/Mn | 26.08K | -54.0% | $706,535 | 0.0% | ▼ Trim | 2 | SEC ↗ ×4 |
| 57 | Raymond James Financial Inc | 24.68K | -1.2% | $668,500 | 0.0% | ▼ Trim | 2 | SEC ↗ ×2 |
| 58 | Creative Planning | 24.30K | +15.2% | $658,314 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 59 | Allianz Asset Management GmbH | 21.90K | -27.5% | $593,271 | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 60 | Quantinno Capital Management LP | 20.54K | +12.6% | $556,456 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 61 | Nomura Holdings Inc | 20.00K | New | $541,800 | 0.0% | New | 1 | SEC ↗ |
| 62 | Janus Henderson Group Plc | 19.85K | -98.4% | $537,285 | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 63 | Universal- Beteiligungs- und… | 19.69K | +64.1% | $533,375 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 64 | Zurcher Kantonalbank (Zurich… | 19.64K | +13.2% | $532,075 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 65 | Simplex Trading, Llc | 19.56K | +307.4% | $529,934 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 66 | Bnp Paribas Financial Markets | 16.72K | -90.3% | $452,836 | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 67 | Susquehanna International Group, Llp | 15.77K | -89.0% | $427,209 | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 68 | New York State Common Retirement… | 15.36K | +22.3% | $416,211 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 69 | Citigroup Inc | 15.09K | -17.6% | $408,652 | 0.0% | ▼ Trim | 2 | SEC ↗ ×2 |
| 70 | Sei Investments Co | 11.69K | +33.2% | $316,730 | 0.0% | ▲ Add | 2 | SEC ↗ ×2 |
| 71 | ProShare Advisors LLC | 10.46K | -13.1% | $283,335 | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 72 | Man Group plc | 10.14K | New | $274,666 | 0.0% | New | 1 | SEC ↗ ×2 |
| 73 | Capstone Investment Advisors, Llc | 9.68K | New | $262,096 | 0.0% | New | 1 | SEC ↗ |
| 74 | Marshall Wace ✦ | 8.99K | -96.4% | $243,458 | 0.0% | ▼ Trim | 2 | SEC ↗ ×2 |
| 75 | State Board Of Administration Of… | 7.67K | +1.5% | $207,834 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 76 | Cwm, Llc | 6.05K | +18.7% | $163,922 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 77 | Mirae Asset Global Investments Co.… | 4.13K | +7.3% | $111,828 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 78 | Pnc Financial Services Group, Inc. | 2.23K | 0.0% | $60,519 | 0.0% | Held | 2 | SEC ↗ ×3 |
| 79 | Osaic Holdings, Inc. | 1.16K | +0.4% | $31,424 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 80 | BNP Paribas Asset Management… | 837 | New | $22,674 | 0.0% | New | 1 | SEC ↗ |
| 81 | Fifth Third Bancorp | 784 | New | $21,240 | 0.0% | New | 1 | SEC ↗ |
| 82 | Rockefeller Capital Management L.P. | 555 | +314.2% | $15,035 | 0.0% | ▲ Add | 2 | SEC ↗ ×3 |
| 83 | Us Bancorp \De\ | 302 | +272.8% | $8,181 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 84 | FIL Ltd | 229 | New | $6,204 | 0.0% | New | 1 | SEC ↗ |
| 85 | Royal Bank Of Canada | 152 | -90.1% | $4,000 | 0.0% | ▼ Trim | 2 | SEC ↗ ×3 |
| 86 | Optiver Holding B.V. | 80 | +90.5% | $2,167 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 87 | Nomura Asset Management Co Ltd | 0 | n/a | $0 | 0.0% | Held | 2 | SEC ↗ |
“Their weight” = the position's share of that manager's reported 13F equity value: the conviction measure. ✦ = curated manager.
New buyers
| Capital World Investors | $10.79M | 0.0% |
| Nomura Holdings Inc | $541,800 | 0.0% |
| Man Group plc | $274,666 | 0.0% |
| Capstone Investment Advisors… | $262,096 | 0.0% |
| BNP Paribas Asset Management… | $22,674 | 0.0% |
| Fifth Third Bancorp | $21,240 | 0.0% |
| FIL Ltd | $6,204 | 0.0% |
Exited
| Holocene Advisors, LP | $58.14M | was 0.1% |
| Capital International… | $42.22M | was 0.0% |
| Mariner, LLC | $371,452 | was 0.0% |
| Connor, Clark & Lunn… | $248,949 | was 0.0% |
| Daiwa Securities Group Inc. | $9,000 | was 0.0% |
Full-market context: across ALL 13F filers (SEC structured data, Q1 2026): 213 holders, 90.27M shares, $2.39B reported. This is a different, older period than the tracked-universe figures above and the two are never mixed.
Frequently co-owned
What else this security's tracked holders most often hold: shared-ownership counts, not fundamental relationships.
Open-market purchases (P)
No open-market insider purchases in our coverage window.
Open-market sales (S)
Sep 30
Congleton Jon
Officer, Director · 75.00K sh · $1.91M
Sep 22
Slingsby Brian Taylor
Director · 104.32K sh · $3.01M
Sep 21
Warren Eric
Officer · 7.44K sh · $209,136
Sep 15
Karydas Daphne
Director · 3.00K sh · $85,740
Aug 21
Warren Eric
Officer · 7.44K sh · $193,189
Aug 10
Rodman David Malcom
Officer · 2.17K sh · $58,785
Awards, exercises and tax withholding are never counted as buys or sales here. Methodology
Aug 06
SC 13G/A: FMR LLC
Provenance: Ownership from parsed 13F common-stock positions (tracked universe, comparable sets for changes); insider rows from Forms 3/4/5; stakes from Schedules 13D/13G; every filing links to its original on SEC EDGAR.
Reporting period: Q1 2026 ·
Methodology ·
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