证券记录 · 已归档季度
MLYS
Mineralys Therapeutics, Inc. · Healthcare · Biotechnology
84被追踪持有人
+1Δ持有人
40.64M持有股份
$1.47B报告持仓市值
+2新建仓位
−1清仓
动量输入（同类管理人）：
持有人广度 +1.2% ·
股份流向 +17.3% ·
净新建仓位 +1.2%
· 公式
广泛增持：持股数量上升，持有人数量增加
所有持股数据：仅限已追踪的 13F 管理人，普通股持仓，报告期 Q4 2025
持股变化趋势
| 季度 | 持有人 | Δ | 股份 | 报告持仓市值 | 新增 | 清仓 |
|---|---|---|---|---|---|---|
| Q2 2026 | 86 | +2 | 43.69M | $1.18B | +8 | −6 |
| Q1 2026 | 87 | +2 | 39.40M | $1.08B | +7 | −5 |
| Q4 2025 | 84 | +1 | 40.64M | $1.47B | +2 | −1 |
| Q3 2025 | 17 | +2 | 19.50M | $739.53M | +2 | n/a |
| Q2 2025 | 12 | -1 | 9.30M | $125.82M | n/a | −1 |
| Q1 2025 | 10 | +4 | 2.76M | $43.90M | +4 | n/a |
| Q4 2024 | 6 | 0 | 2.45M | $30.15M | +1 | −1 |
| Q3 2024 | 5 | 0 | 890.52K | $10.79M | +1 | −1 |
| Q2 2024 | 5 | n/a | 738.83K | $8.65M | n/a | n/a |
持有人 · Q4 2025
| # | 管理人 | 股份 | Δ股份 | 价值 | 其权重 | 持有 | ||
|---|---|---|---|---|---|---|---|---|
| 1 | Fidelity (FMR) ✦ | 5.06M | +144.2% | $183.54M | 0.0% | ▲ Add | 3 | SEC ↗ ×4 |
| 2 | BlackRock ✦ (被动) | 4.33M | +17.9% | $157.05M | 0.0% | ▲ Add | 3 | SEC ↗ ×13 |
| 3 | The Vanguard Group ✦ (被动) | 3.35M | +11.1% | $121.68M | 0.0% | ▲ Add | 3 | SEC ↗ ×5 |
| 4 | State Street Global Advisors ✦ (被动) | 3.18M | +144.4% | $115.58M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 5 | Franklin Resources Inc | 1.79M | n/a | $64.91M | 0.0% | n/c | 1 | SEC ↗ ×4 |
| 6 | Holocene Advisors, LP | 1.60M | n/a | $58.14M | 0.1% | n/c | 1 | SEC ↗ |
| 7 | Goldman Sachs Group ✦ | 1.45M | +103.9% | $52.65M | 0.0% | ▲ Add | 2 | SEC ↗ ×2 |
| 8 | T. Rowe Price ✦ | 1.33M | +6097.1% | $48.09M | 0.0% | ▲ Add | 5 | SEC ↗ ×2 |
| 9 | Jennison Associates Llc | 1.26M | n/a | $45.68M | 0.0% | n/c | 1 | SEC ↗ |
| 10 | Geode Capital Management ✦ (被动) | 1.26M | +11.9% | $45.64M | 0.0% | ▲ Add | 7 | SEC ↗ ×2 |
| 11 | Janus Henderson Group Plc | 1.21M | n/a | $44.01M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 12 | Point72 Asset Management ✦ | 1.21M | -32.9% | $43.81M | 0.1% | ▼ Trim | 2 | SEC ↗ |
| 13 | Capital International Investors | 1.16M | n/a | $42.22M | 0.0% | n/c | 1 | SEC ↗ |
| 14 | D. E. Shaw & Co. ✦ | 1.15M | +88.3% | $41.76M | 0.0% | ▲ Add | 4 | SEC ↗ |
| 15 | Bank Of America Corp /De/ | 987.28K | n/a | $35.83M | 0.0% | n/c | 1 | SEC ↗ ×5 |
| 16 | Alliancebernstein L.P. | 922.52K | n/a | $33.48M | 0.0% | n/c | 1 | SEC ↗ |
| 17 | American Century Companies Inc | 908.09K | n/a | $32.95M | 0.0% | n/c | 1 | SEC ↗ |
| 18 | Pictet Asset Management Holding SA | 852.88K | n/a | $30.95M | 0.0% | n/c | 1 | SEC ↗ |
| 19 | Wellington Management ✦ | 784.27K | +0.1% | $28.46M | 0.0% | ▲ Add | 6 | SEC ↗ ×7 |
| 20 | Morgan Stanley ✦ | 639.51K | -53.6% | $23.21M | 0.0% | ▼ Trim | 2 | SEC ↗ ×9 |
| 21 | Two Sigma Investments ✦ | 610.40K | 新增 | $22.15M | 0.0% | New | 1 | SEC ↗ |
| 22 | Qube Research & Technologies Ltd | 496.55K | n/a | $18.02M | 0.0% | n/c | 1 | SEC ↗ |
| 23 | Charles Schwab Investment… | 461.30K | n/a | $16.74M | 0.0% | n/c | 1 | SEC ↗ |
| 24 | Citadel Advisors ✦ | 399.92K | -80.7% | $14.51M | 0.0% | ▼ Trim | 4 | SEC ↗ ×2 |
| 25 | Renaissance Technologies ✦ | 322.10K | +579.5% | $11.69M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 26 | Northern Trust Corp | 299.86K | n/a | $10.88M | 0.0% | n/c | 1 | SEC ↗ ×5 |
| 27 | Marshall Wace ✦ | 249.13K | 新增 | $9.04M | 0.0% | New | 1 | SEC ↗ ×2 |
| 28 | Squarepoint Ops LLC | 246.80K | n/a | $8.96M | 0.0% | n/c | 1 | SEC ↗ |
| 29 | Barclays Plc | 223.28K | n/a | $8.10M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 30 | Swedbank AB | 221.40K | n/a | $8.03M | 0.0% | n/c | 1 | SEC ↗ |
| 31 | UBS Group AG | 201.28K | n/a | $7.30M | 0.0% | n/c | 1 | SEC ↗ ×4 |
| 32 | Russell Investments Group, Ltd. | 175.36K | n/a | $6.36M | 0.0% | n/c | 1 | SEC ↗ ×5 |
| 33 | Bnp Paribas Financial Markets | 172.93K | n/a | $6.28M | 0.0% | n/c | 1 | SEC ↗ |
| 34 | Susquehanna International Group, Llp | 143.21K | n/a | $5.20M | 0.0% | n/c | 1 | SEC ↗ |
| 35 | Dimensional Fund Advisors Lp | 137.64K | n/a | $4.99M | 0.0% | n/c | 1 | SEC ↗ ×4 |
| 36 | Bank of New York Mellon Corp | 131.84K | n/a | $4.78M | 0.0% | n/c | 1 | SEC ↗ ×6 |
| 37 | Nuveen, LLC | 122.95K | n/a | $4.46M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 38 | Voya Investment Management Llc | 112.67K | n/a | $4.09M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 39 | Ensign Peak Advisors, Inc | 112.19K | n/a | $4.07M | 0.0% | n/c | 1 | SEC ↗ |
| 40 | DZ BANK AG Deutsche Zentral… | 111.75K | n/a | $4.06M | 0.0% | n/c | 1 | SEC ↗ |
| 41 | Swiss National Bank | 90.10K | n/a | $3.27M | 0.0% | n/c | 1 | SEC ↗ |
| 42 | Prudential Financial Inc | 89.06K | n/a | $3.23M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 43 | Hrt Financial Lp | 87.24K | n/a | $3.17M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 44 | Millennium Management ✦ | 78.62K | -80.6% | $2.85M | 0.0% | ▼ Trim | 7 | SEC ↗ |
| 45 | UBS AM, a distinct business unit of… | 75.90K | n/a | $2.75M | 0.0% | n/c | 1 | SEC ↗ ×6 |
| 46 | AQR Capital Management ✦ | 62.30K | +243.8% | $2.26M | 0.0% | ▲ Add | 4 | SEC ↗ ×6 |
| 47 | Wells Fargo & Company/Mn | 56.76K | n/a | $2.06M | 0.0% | n/c | 1 | SEC ↗ ×4 |
| 48 | Rhumbline Advisers | 54.28K | n/a | $1.97M | 0.0% | n/c | 1 | SEC ↗ |
| 49 | State Of Wisconsin Investment Board | 49.94K | n/a | $1.81M | 0.0% | n/c | 1 | SEC ↗ |
| 50 | JPMorgan Chase ✦ | 46.68K | -87.3% | $1.69M | 0.0% | ▼ Trim | 2 | SEC ↗ ×4 |
| 51 | Ameriprise Financial Inc | 46.25K | n/a | $1.68M | 0.0% | n/c | 1 | SEC ↗ |
| 52 | Legal & General Group Plc | 43.94K | n/a | $1.59M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 53 | California State Teachers… | 43.35K | n/a | $1.57M | 0.0% | n/c | 1 | SEC ↗ |
| 54 | Tudor Investment Corp Et Al | 39.05K | n/a | $1.42M | 0.0% | n/c | 1 | SEC ↗ |
| 55 | Deutsche Bank Ag\ | 37.24K | n/a | $1.35M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 56 | Victory Capital Management Inc | 32.88K | n/a | $1.19M | 0.0% | n/c | 1 | SEC ↗ |
| 57 | Allianz Asset Management GmbH | 30.20K | n/a | $1.10M | 0.0% | n/c | 1 | SEC ↗ |
| 58 | Canada Pension Plan Investment Board | 29.60K | n/a | $1.07M | 0.0% | n/c | 1 | SEC ↗ |
| 59 | Invesco Ltd. | 29.14K | n/a | $1.06M | 0.0% | n/c | 1 | SEC ↗ ×4 |
| 60 | MIRAE ASSET GLOBAL ETFS HOLDINGS… | 29.18K | n/a | $1.05M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 61 | Raymond James Financial Inc | 24.97K | n/a | $906,306 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 62 | Creative Planning | 21.10K | n/a | $765,828 | 0.0% | n/c | 1 | SEC ↗ |
| 63 | Citigroup Inc | 18.32K | n/a | $664,651 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 64 | Quantinno Capital Management LP | 18.24K | n/a | $662,038 | 0.0% | n/c | 1 | SEC ↗ |
| 65 | Zurcher Kantonalbank (Zurich… | 17.35K | n/a | $629,559 | 0.0% | n/c | 1 | SEC ↗ |
| 66 | Manufacturers Life Insurance… | 16.18K | n/a | $587,208 | 0.0% | n/c | 1 | SEC ↗ |
| 67 | New York State Common Retirement… | 12.56K | n/a | $455,948 | 0.0% | n/c | 1 | SEC ↗ |
| 68 | ProShare Advisors LLC | 12.04K | n/a | $436,932 | 0.0% | n/c | 1 | SEC ↗ |
| 69 | Universal- Beteiligungs- und… | 12.00K | n/a | $435,371 | 0.0% | n/c | 1 | SEC ↗ |
| 70 | Mariner, LLC | 10.23K | n/a | $371,452 | 0.0% | n/c | 1 | SEC ↗ |
| 71 | Sei Investments Co | 8.78K | n/a | $318,624 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 72 | State Board Of Administration Of… | 7.56K | n/a | $274,389 | 0.0% | n/c | 1 | SEC ↗ |
| 73 | Connor, Clark & Lunn Investment… | 6.86K | n/a | $248,949 | 0.0% | n/c | 1 | SEC ↗ |
| 74 | Cwm, Llc | 5.10K | n/a | $185,000 | 0.0% | n/c | 1 | SEC ↗ |
| 75 | Simplex Trading, Llc | 4.80K | n/a | $174,264 | 0.0% | n/c | 1 | SEC ↗ |
| 76 | Mirae Asset Global Investments Co.… | 3.85K | n/a | $139,571 | 0.0% | n/c | 1 | SEC ↗ |
| 77 | Pnc Financial Services Group, Inc. | 2.23K | n/a | $81,072 | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 78 | Royal Bank Of Canada | 1.53K | n/a | $56,000 | 0.0% | n/c | 1 | SEC ↗ ×4 |
| 79 | Osaic Holdings, Inc. | 1.16K | n/a | $41,915 | 0.0% | n/c | 1 | SEC ↗ |
| 80 | Daiwa Securities Group Inc. | 235 | n/a | $9,000 | 0.0% | n/c | 1 | SEC ↗ |
| 81 | Rockefeller Capital Management L.P. | 134 | n/a | $4,863 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 82 | Us Bancorp \De\ | 81 | n/a | $2,939 | 0.0% | n/c | 1 | SEC ↗ |
| 83 | Optiver Holding B.V. | 42 | n/a | $1,524 | 0.0% | n/c | 1 | SEC ↗ |
| 84 | Nomura Asset Management Co Ltd | 0 | n/a | $0 | 0.0% | n/c | 1 | SEC ↗ |
"持仓权重"指该仓位占该管理人13F申报股票组合市值的比例，即持仓信心指标。✦ = 精选管理人。
新增买入方
| Two Sigma Investments | $22.15M | 0.0% |
| Marshall Wace | $9.04M | 0.0% |
已清仓
| Adage Capital Partners | $3.98M | 曾为 0.0% |
全市场背景: 涵盖所有13F申报机构（SEC结构化数据， Q1 2026): 213 持有人, 90.27M 股份, $2.39B 已申报. 这是与上方被追踪全域数据不同的较早期间，两者从不混用。
常见共同持仓
持有该证券的受追踪机构最常同时持有的其他证券：基于共同持有计数，而非基本面关联。
公开市场买入 (P)
在我们的覆盖窗口内无内部人士公开市场买入记录。
公开市场卖出 (S)
Sep 30
Congleton Jon
Officer, Director · 75.00K 股 · $1.91M
Sep 22
Slingsby Brian Taylor
Director · 104.32K 股 · $3.01M
Sep 21
Warren Eric
Officer · 7.44K 股 · $209,136
Sep 15
Karydas Daphne
Director · 3.00K 股 · $85,740
Aug 21
Warren Eric
Officer · 7.44K 股 · $193,189
Aug 10
Rodman David Malcom
Officer · 2.17K 股 · $58,785
授予、行权及税务代扣代缴在本平台均不计入买入或卖出。 方法论
Aug 06
SC 13G/A: FMR LLC
数据来源: 持股数据来源于已解析的13F普通股持仓（被追踪范围，变动对比集）；内部人行为来自Form 3/4/5；重大持股来自Schedule 13D/13G；所有文件均链接至SEC EDGAR原始申报。
报告期: Q4 2025 ·
方法论 ·
通过API获取此数据