Security record · archived quarter
LXRX
Lexicon Pharmaceuticals, Inc. · Healthcare · Biotechnology
51Tracked holders
+1Δ holders
73.64MShares held
$84.69MReported value
+2New positions
−1Exits
Momentum inputs (comparable managers):
holder breadth +2.0% ·
share flow +2.0% ·
net new positions +2.0%
· formula
Broad accumulation: rising shares across more holders
All ownership figures: tracked 13F managers only, common-stock positions, reporting period Q4 2025
Ownership over time
| Quarter | Holders | Δ | Shares | Reported value | New | Exits |
|---|---|---|---|---|---|---|
| Q3 2026 | 1 | 0 | 11.77K | $20,706 | n/a | n/a |
| Q2 2026 | 68 | +16 | 115.42M | $276.97M | +20 | −4 |
| Q1 2026 | 53 | +1 | 96.42M | $150.42M | +5 | −4 |
| Q4 2025 | 51 | +1 | 73.64M | $84.69M | +2 | −1 |
| Q3 2025 | 13 | 0 | 62.78M | $84.76M | +2 | −2 |
| Q2 2025 | 10 | +2 | 57.50M | $54.38M | +4 | −2 |
| Q1 2025 | 5 | -2 | 7.56M | $3.49M | +1 | −3 |
| Q4 2024 | 7 | -2 | 16.13M | $11.91M | +1 | −3 |
| Q3 2024 | 8 | 0 | 7.88M | $12.37M | n/a | n/a |
| Q2 2024 | 8 | n/a | 12.44M | $20.91M | n/a | n/a |
Who holds it · Q4 2025
| # | Manager | Shares | Δ shares | Value | Their weight | Held | ||
|---|---|---|---|---|---|---|---|---|
| 1 | Fidelity (FMR) ✦ | 37.83M | -2.2% | $43.51M | 0.0% | ▼ Trim | 3 | SEC ↗ ×3 |
| 2 | The Vanguard Group ✦ (passive) | 9.61M | +0.9% | $11.05M | 0.0% | ▲ Add | 3 | SEC ↗ ×3 |
| 3 | Millennium Management ✦ | 4.82M | +25.9% | $5.54M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 4 | BlackRock ✦ (passive) | 3.19M | -6.0% | $3.67M | 0.0% | ▼ Trim | 3 | SEC ↗ ×4 |
| 5 | UBS Group AG | 3.01M | n/a | $3.46M | 0.0% | n/c | 1 | SEC ↗ ×4 |
| 6 | Geode Capital Management ✦ (passive) | 2.50M | +4.3% | $2.88M | 0.0% | ▲ Add | 7 | SEC ↗ ×2 |
| 7 | Jane Street Group, Llc | 1.72M | n/a | $1.98M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 8 | Citadel Advisors ✦ | 1.71M | -35.0% | $1.97M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 9 | Marshall Wace ✦ | 1.26M | New | $1.45M | 0.0% | New | 1 | SEC ↗ ×3 |
| 10 | Susquehanna International Group, Llp | 1.21M | n/a | $1.39M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 11 | Charles Schwab Investment… | 1.06M | n/a | $1.21M | 0.0% | n/c | 1 | SEC ↗ |
| 12 | Goldman Sachs Group ✦ | 921.20K | +1452.2% | $1.06M | 0.0% | ▲ Add | 2 | SEC ↗ ×2 |
| 13 | State Street Global Advisors ✦ (passive) | 884.74K | +0.5% | $1.02M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 14 | Two Sigma Investments ✦ | 637.31K | +14.0% | $732,904 | 0.0% | ▲ Add | 3 | SEC ↗ |
| 15 | Invesco Ltd. | 594.88K | n/a | $684,115 | 0.0% | n/c | 1 | SEC ↗ |
| 16 | Northern Trust Corp | 412.16K | n/a | $473,989 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 17 | Point72 Asset Management ✦ | 284.02K | New | $326,629 | 0.0% | New | 1 | SEC ↗ |
| 18 | Renaissance Technologies ✦ | 263.25K | -10.0% | $302,742 | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 19 | Group One Trading Llc | 224.31K | n/a | $257,954 | 0.0% | n/c | 1 | SEC ↗ |
| 20 | Barclays Plc | 194.74K | n/a | $223,954 | 0.0% | n/c | 1 | SEC ↗ |
| 21 | Morgan Stanley ✦ | 193.03K | +14.2% | $221,990 | 0.0% | ▲ Add | 2 | SEC ↗ ×5 |
| 22 | Cerity Partners LLC | 144.94K | n/a | $166,686 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 23 | AQR Capital Management ✦ | 144.80K | -52.2% | $166,520 | 0.0% | ▼ Trim | 4 | SEC ↗ ×3 |
| 24 | Hrt Financial Lp | 117.55K | n/a | $135,000 | 0.0% | n/c | 1 | SEC ↗ |
| 25 | Bank Of America Corp /De/ | 102.10K | n/a | $117,412 | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 26 | Citigroup Inc | 91.67K | n/a | $105,421 | 0.0% | n/c | 1 | SEC ↗ |
| 27 | LPL Financial LLC | 87.06K | n/a | $100,116 | 0.0% | n/c | 1 | SEC ↗ |
| 28 | Bank Of Montreal /Can/ | 70.00K | n/a | $80,500 | 0.0% | n/c | 1 | SEC ↗ |
| 29 | Squarepoint Ops LLC | 60.47K | n/a | $69,543 | 0.0% | n/c | 1 | SEC ↗ |
| 30 | Optiver Holding B.V. | 52.59K | n/a | $60,484 | 0.0% | n/c | 1 | SEC ↗ |
| 31 | CIBC Asset Management Inc | 39.52K | n/a | $45,448 | 0.0% | n/c | 1 | SEC ↗ |
| 32 | Prudential Financial Inc | 33.80K | n/a | $38,870 | 0.0% | n/c | 1 | SEC ↗ |
| 33 | Victory Capital Management Inc | 21.19K | n/a | $24,370 | 0.0% | n/c | 1 | SEC ↗ |
| 34 | Bank of New York Mellon Corp | 19.12K | n/a | $21,992 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 35 | Credit Agricole S A | 18.98K | n/a | $21,821 | 0.0% | n/c | 1 | SEC ↗ |
| 36 | Simplex Trading, Llc | 14.76K | n/a | $16,971 | 0.0% | n/c | 1 | SEC ↗ |
| 37 | Cetera Investment Advisers | 14.19K | n/a | $16,316 | 0.0% | n/c | 1 | SEC ↗ |
| 38 | Lazard Asset Management Llc | 14.09K | n/a | $16,204 | 0.0% | n/c | 1 | SEC ↗ |
| 39 | Truist Financial Corp | 14.00K | n/a | $16,100 | 0.0% | n/c | 1 | SEC ↗ |
| 40 | Wealth Enhancement Advisory… | 13.52K | n/a | $15,413 | 0.0% | n/c | 1 | SEC ↗ |
| 41 | Cwm, Llc | 13.18K | n/a | $15,000 | 0.0% | n/c | 1 | SEC ↗ |
| 42 | Captrust Financial Advisors | 11.73K | n/a | $13,495 | 0.0% | n/c | 1 | SEC ↗ |
| 43 | Royal Bank Of Canada | 6.77K | n/a | $7,000 | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 44 | Pnc Financial Services Group, Inc. | 1.46K | n/a | $1,679 | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 45 | Jones Financial Companies Lllp | 1.11K | n/a | $1,272 | 0.0% | n/c | 1 | SEC ↗ |
| 46 | Osaic Holdings, Inc. | 642 | n/a | $738 | 0.0% | n/c | 1 | SEC ↗ |
| 47 | Northwestern Mutual Wealth… | 500 | n/a | $575 | 0.0% | n/c | 1 | SEC ↗ |
| 48 | Rockefeller Capital Management L.P. | 335 | n/a | $385 | 0.0% | n/c | 1 | SEC ↗ |
| 49 | Bnp Paribas Financial Markets | 11 | n/a | $13 | 0.0% | n/c | 1 | SEC ↗ |
| 50 | Rhumbline Advisers | 0 | n/a | $2 | 0.0% | n/c | 1 | SEC ↗ |
| 51 | Wells Fargo & Company/Mn | 1 | n/a | $1 | 0.0% | n/c | 1 | SEC ↗ |
“Their weight” = the position's share of that manager's reported 13F equity value: the conviction measure. ✦ = curated manager.
New buyers
| Marshall Wace | $1.45M | 0.0% |
| Point72 Asset Management | $326,629 | 0.0% |
Exited
| JPMorgan Chase | $81,100 | was 0.0% |
Full-market context: across ALL 13F filers (SEC structured data, Q1 2026): 136 holders, 323.38M shares, $502.11M reported. This is a different, older period than the tracked-universe figures above and the two are never mixed.
Frequently co-owned
What else this security's tracked holders most often hold: shared-ownership counts, not fundamental relationships.
Provenance: Ownership from parsed 13F common-stock positions (tracked universe, comparable sets for changes); insider rows from Forms 3/4/5; stakes from Schedules 13D/13G; every filing links to its original on SEC EDGAR.
Reporting period: Q4 2025 ·
Methodology ·
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