Security record · archived quarter
IRON
Disc Medicine, Inc. · Healthcare · Biotechnology
77Tracked holders
-1Δ holders
22.10MShares held
$1.75BReported value
+1New positions
−2Exits
Momentum inputs (comparable managers):
holder breadth -1.3% ·
share flow +8.6% ·
net new positions -1.3%
— formula
Concentrated accumulation — rising shares among fewer holders
All ownership figures: tracked 13F managers only, common-stock positions, reporting period Q4 2025
Ownership over time
| Quarter | Holders | Δ | Shares | Reported value | New | Exits |
|---|---|---|---|---|---|---|
| Q2 2026 | 83 | +7 | 22.99M | $1.68B | +9 | −2 |
| Q1 2026 | 79 | +1 | 22.38M | $1.43B | +7 | −6 |
| Q4 2025 | 77 | -1 | 22.10M | $1.75B | +1 | −2 |
| Q3 2025 | 17 | +3 | 15.61M | $1.03B | +3 | — |
| Q2 2025 | 11 | -1 | 11.75M | $622.02M | +1 | −2 |
| Q1 2025 | 9 | -1 | 6.07M | $301.51M | — | −1 |
| Q4 2024 | 10 | +3 | 5.16M | $327.26M | +3 | — |
| Q3 2024 | 6 | -1 | 5.16M | $253.75M | — | −1 |
| Q2 2024 | 7 | — | 5.00M | $225.18M | — | — |
Who holds it · Q4 2025
| # | Manager | Shares | Δ shares | Value | Their weight | Held | ||
|---|---|---|---|---|---|---|---|---|
| 1 | Fidelity (FMR) ✦ | 5.45M | +10.4% | $432.80M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 2 | Fidelity (FMR) ✦ | 5.45M | +10.4% | $432.80M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 3 | Fidelity (FMR) ✦ | 5.45M | +10.4% | $432.80M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 4 | Fidelity (FMR) ✦ | 5.45M | +10.4% | $432.80M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 5 | Fidelity (FMR) ✦ | 5.45M | +10.4% | $432.80M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 6 | BlackRock ✦ (passive) | 2.27M | +12.7% | $180.66M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 7 | BlackRock ✦ (passive) | 2.27M | +12.7% | $180.66M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 8 | BlackRock ✦ (passive) | 2.27M | +12.7% | $180.66M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 9 | BlackRock ✦ (passive) | 2.27M | +12.7% | $180.66M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 10 | BlackRock ✦ (passive) | 2.27M | +12.7% | $180.66M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 11 | BlackRock ✦ (passive) | 2.27M | +12.7% | $180.66M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 12 | BlackRock ✦ (passive) | 2.27M | +12.7% | $180.66M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 13 | BlackRock ✦ (passive) | 2.27M | +12.7% | $180.66M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 14 | BlackRock ✦ (passive) | 2.27M | +12.7% | $180.66M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 15 | BlackRock ✦ (passive) | 2.27M | +12.7% | $180.66M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 16 | BlackRock ✦ (passive) | 2.27M | +12.7% | $180.66M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 17 | BlackRock ✦ (passive) | 2.27M | +12.7% | $180.66M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 18 | BlackRock ✦ (passive) | 2.27M | +12.7% | $180.66M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 19 | The Vanguard Group ✦ (passive) | 1.77M | +22.1% | $140.37M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 20 | The Vanguard Group ✦ (passive) | 1.77M | +22.1% | $140.37M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 21 | The Vanguard Group ✦ (passive) | 1.77M | +22.1% | $140.37M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 22 | The Vanguard Group ✦ (passive) | 1.77M | +22.1% | $140.37M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 23 | The Vanguard Group ✦ (passive) | 1.77M | +22.1% | $140.37M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 24 | T. Rowe Price ✦ | 1.70M | +28.0% | $134.84M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 25 | T. Rowe Price ✦ | 1.70M | +28.0% | $134.84M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 26 | JPMorgan Chase ✦ | 1.58M | +5.0% | $125.56M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 27 | JPMorgan Chase ✦ | 1.58M | +5.0% | $125.56M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 28 | JPMorgan Chase ✦ | 1.58M | +5.0% | $125.56M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 29 | JPMorgan Chase ✦ | 1.58M | +5.0% | $125.56M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 30 | JPMorgan Chase ✦ | 1.58M | +5.0% | $125.56M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 31 | JPMorgan Chase ✦ | 1.58M | +5.0% | $125.56M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 32 | Wellington Management ✦ | 1.52M | +7.7% | $120.57M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 33 | Wellington Management ✦ | 1.52M | +7.7% | $120.57M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 34 | Wellington Management ✦ | 1.52M | +7.7% | $120.57M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 35 | Wellington Management ✦ | 1.52M | +7.7% | $120.57M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 36 | Wellington Management ✦ | 1.52M | +7.7% | $120.57M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 37 | Wellington Management ✦ | 1.52M | +7.7% | $120.57M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 38 | Wellington Management ✦ | 1.52M | +7.7% | $120.57M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 39 | Wellington Management ✦ | 1.52M | +7.7% | $120.57M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 40 | State Street Global Advisors ✦ (passive) | 1.19M | +13.6% | $94.34M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 41 | Goldman Sachs Group ✦ | 754.20K | +42.5% | $59.89M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 42 | Goldman Sachs Group ✦ | 754.20K | +42.5% | $59.89M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 43 | Geode Capital Management ✦ (passive) | 684.96K | +9.0% | $54.40M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 44 | Geode Capital Management ✦ (passive) | 684.96K | +9.0% | $54.40M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 45 | Jennison Associates Llc | 532.08K | — | $42.25M | 0.0% | n/c | 1 | SEC ↗ |
| 46 | Pictet Asset Management Holding SA | 394.37K | — | $31.32M | 0.0% | n/c | 1 | SEC ↗ |
| 47 | Assenagon Asset Management S.A. | 357.84K | — | $28.42M | 0.0% | n/c | 1 | SEC ↗ |
| 48 | Loomis Sayles & Co L P | 282.41K | — | $22.43M | 0.0% | n/c | 1 | SEC ↗ |
| 49 | Loomis Sayles & Co L P | 282.41K | — | $22.43M | 0.0% | n/c | 1 | SEC ↗ |
| 50 | Charles Schwab Investment… | 247.04K | — | $19.62M | 0.0% | n/c | 1 | SEC ↗ |
| 51 | Aberdeen Group plc | 234.36K | — | $18.61M | 0.0% | n/c | 1 | SEC ↗ |
| 52 | Northern Trust Corp | 228.07K | — | $18.11M | 0.0% | n/c | 1 | SEC ↗ |
| 53 | Northern Trust Corp | 228.07K | — | $18.11M | 0.0% | n/c | 1 | SEC ↗ |
| 54 | Northern Trust Corp | 228.07K | — | $18.11M | 0.0% | n/c | 1 | SEC ↗ |
| 55 | Northern Trust Corp | 228.07K | — | $18.11M | 0.0% | n/c | 1 | SEC ↗ |
| 56 | Northern Trust Corp | 228.07K | — | $18.11M | 0.0% | n/c | 1 | SEC ↗ |
| 57 | Northern Trust Corp | 228.07K | — | $18.11M | 0.0% | n/c | 1 | SEC ↗ |
| 58 | Dimensional Fund Advisors Lp | 223.57K | — | $17.75M | 0.0% | n/c | 1 | SEC ↗ |
| 59 | Dimensional Fund Advisors Lp | 223.57K | — | $17.75M | 0.0% | n/c | 1 | SEC ↗ |
| 60 | Dimensional Fund Advisors Lp | 223.57K | — | $17.75M | 0.0% | n/c | 1 | SEC ↗ |
| 61 | Dimensional Fund Advisors Lp | 223.57K | — | $17.75M | 0.0% | n/c | 1 | SEC ↗ |
| 62 | Dimensional Fund Advisors Lp | 223.57K | — | $17.75M | 0.0% | n/c | 1 | SEC ↗ |
| 63 | Balyasny Asset Management L.P. | 221.76K | — | $17.61M | 0.0% | n/c | 1 | SEC ↗ |
| 64 | Millennium Management ✦ | 184.78K | +14.8% | $14.67M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 65 | Ensign Peak Advisors, Inc | 177.05K | — | $14.06M | 0.0% | n/c | 1 | SEC ↗ |
| 66 | Bank Of America Corp /De/ | 135.99K | — | $10.80M | 0.0% | n/c | 1 | SEC ↗ |
| 67 | Bank Of America Corp /De/ | 135.99K | — | $10.80M | 0.0% | n/c | 1 | SEC ↗ |
| 68 | Bank Of America Corp /De/ | 135.99K | — | $10.80M | 0.0% | n/c | 1 | SEC ↗ |
| 69 | Bank Of America Corp /De/ | 135.99K | — | $10.80M | 0.0% | n/c | 1 | SEC ↗ |
| 70 | Bank Of America Corp /De/ | 135.99K | — | $10.80M | 0.0% | n/c | 1 | SEC ↗ |
| 71 | Bnp Paribas Financial Markets | 122.15K | — | $9.70M | 0.0% | n/c | 1 | SEC ↗ |
| 72 | UBS Group AG | 116.11K | — | $9.22M | 0.0% | n/c | 1 | SEC ↗ |
| 73 | UBS Group AG | 116.11K | — | $9.22M | 0.0% | n/c | 1 | SEC ↗ |
| 74 | UBS Group AG | 116.11K | — | $9.22M | 0.0% | n/c | 1 | SEC ↗ |
| 75 | UBS Group AG | 116.11K | — | $9.22M | 0.0% | n/c | 1 | SEC ↗ |
| 76 | UBS AM, a distinct business unit of… | 114.35K | — | $9.08M | 0.0% | n/c | 1 | SEC ↗ |
| 77 | UBS AM, a distinct business unit of… | 114.35K | — | $9.08M | 0.0% | n/c | 1 | SEC ↗ |
| 78 | UBS AM, a distinct business unit of… | 114.35K | — | $9.08M | 0.0% | n/c | 1 | SEC ↗ |
| 79 | UBS AM, a distinct business unit of… | 114.35K | — | $9.08M | 0.0% | n/c | 1 | SEC ↗ |
| 80 | UBS AM, a distinct business unit of… | 114.35K | — | $9.08M | 0.0% | n/c | 1 | SEC ↗ |
| 81 | UBS AM, a distinct business unit of… | 114.35K | — | $9.08M | 0.0% | n/c | 1 | SEC ↗ |
| 82 | Citadel Advisors ✦ | 100.39K | +99.2% | $7.97M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 83 | Citadel Advisors ✦ | 100.39K | +99.2% | $7.97M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 84 | Barclays Plc | 99.61K | — | $7.91M | 0.0% | n/c | 1 | SEC ↗ |
| 85 | Barclays Plc | 99.61K | — | $7.91M | 0.0% | n/c | 1 | SEC ↗ |
| 86 | Barclays Plc | 99.61K | — | $7.91M | 0.0% | n/c | 1 | SEC ↗ |
| 87 | Ameriprise Financial Inc | 82.98K | — | $6.59M | 0.0% | n/c | 1 | SEC ↗ |
| 88 | Raymond James Financial Inc | 80.27K | — | $6.18M | 0.0% | n/c | 1 | SEC ↗ |
| 89 | Raymond James Financial Inc | 80.27K | — | $6.18M | 0.0% | n/c | 1 | SEC ↗ |
| 90 | Raymond James Financial Inc | 80.27K | — | $6.18M | 0.0% | n/c | 1 | SEC ↗ |
| 91 | Victory Capital Management Inc | 76.34K | — | $6.06M | 0.0% | n/c | 1 | SEC ↗ |
| 92 | Morgan Stanley ✦ | 74.83K | +33.4% | $5.94M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 93 | Morgan Stanley ✦ | 74.83K | +33.4% | $5.94M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 94 | Morgan Stanley ✦ | 74.83K | +33.4% | $5.94M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 95 | Morgan Stanley ✦ | 74.83K | +33.4% | $5.94M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 96 | Morgan Stanley ✦ | 74.83K | +33.4% | $5.94M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 97 | Morgan Stanley ✦ | 74.83K | +33.4% | $5.94M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 98 | Morgan Stanley ✦ | 74.83K | +33.4% | $5.94M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 99 | Td Asset Management Inc | 69.63K | — | $5.53M | 0.0% | n/c | 1 | SEC ↗ |
| 100 | Bank of New York Mellon Corp | 67.71K | — | $5.38M | 0.0% | n/c | 1 | SEC ↗ |
“Their weight” = the position's share of that manager's reported 13F equity value — the conviction measure. ✦ = curated manager.
New buyers
| No new tracked buyers this quarter. |
Exited
| Adage Capital Partners | $29.74M | was 0.0% |
| Point72 Asset Management | $609,627 | was 0.0% |
Full-market context: across ALL 13F filers (SEC structured data, Q1 2026): 203 holders, 40.63M shares, $2.48B reported. This is a different, older period than the tracked-universe figures above and the two are never mixed.
Frequently co-owned
What else this security's tracked holders most often hold — shared-ownership counts, not fundamental relationships.
Open-market purchases (P)
No open-market insider purchases in our coverage window.
Open-market sales (S)
Aug 17
Quisel John D
Officer, Director · 8.40K sh · $656,091
Aug 17
Quisel John D
Officer, Director · 12.71K sh · $1.01M
Aug 17
Quisel John D
Officer, Director · 11.89K sh · $949,162
Aug 12
Yu Jonathan Yen-Wen
Officer · 804 sh · $66,445
Awards, exercises and tax withholding are never counted as buys or sales here. Methodology
Aug 06
SC 13G/A — FMR LLC
Provenance: Ownership from parsed 13F common-stock positions (tracked universe, comparable sets for changes); insider rows from Forms 3/4/5; stakes from Schedules 13D/13G; every filing links to its original on SEC EDGAR.
Reporting period: Q4 2025 ·
Methodology ·
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