Security record · archived quarter
INSM
Insmed Incorporated · Healthcare · Biotechnology
159Tracked holders
-1Δ holders
156.45MShares held
$27.23BReported value
+1New positions
−1Exits
Momentum inputs (comparable managers):
holder breadth -0.6% ·
share flow -13.5% ·
net new positions 0.0%
· formula
Broad distribution: falling shares and fewer holders
All ownership figures: tracked 13F managers only, common-stock positions, reporting period Q4 2025
Ownership over time
| Quarter | Holders | Δ | Shares | Reported value | New | Exits |
|---|---|---|---|---|---|---|
| Q3 2026 | 3 | 0 | 1.33M | $149.97M | n/a | −2 |
| Q2 2026 | 156 | -6 | 147.06M | $15.68B | +6 | −13 |
| Q1 2026 | 166 | +6 | 152.11M | $24.63B | +9 | −4 |
| Q4 2025 | 159 | -1 | 156.45M | $27.23B | +1 | −1 |
| Q3 2025 | 21 | +1 | 121.03M | $17.43B | +1 | −1 |
| Q2 2025 | 18 | +1 | 70.35M | $7.08B | +2 | −1 |
| Q1 2025 | 14 | -1 | 33.99M | $2.59B | n/a | −1 |
| Q4 2024 | 15 | 0 | 31.46M | $2.17B | +1 | −1 |
| Q3 2024 | 14 | -1 | 23.46M | $1.71B | n/a | −1 |
| Q2 2024 | 15 | n/a | 25.91M | $1.74B | n/a | n/a |
Who holds it · Q4 2025
| # | Manager | Shares | Δ shares | Value | Their weight | Held | ||
|---|---|---|---|---|---|---|---|---|
| 1 | JPMorgan Chase ✦ | 23.20M | -49.7% | $4.04B | 0.3% | ▼ Trim | 2 | SEC ↗ ×15 |
| 2 | The Vanguard Group ✦ (passive) | 21.08M | +5.7% | $3.67B | 0.1% | ▲ Add | 3 | SEC ↗ ×5 |
| 3 | BlackRock ✦ (passive) | 15.07M | +21.8% | $2.62B | 0.0% | ▲ Add | 3 | SEC ↗ ×22 |
| 4 | Fidelity (FMR) ✦ | 9.93M | +8.1% | $1.73B | 0.1% | ▲ Add | 3 | SEC ↗ ×6 |
| 5 | Invesco Ltd. | 7.52M | n/a | $1.31B | 0.1% | n/c | 1 | SEC ↗ ×12 |
| 6 | State Street Global Advisors ✦ (passive) | 5.20M | +30.6% | $905.31M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 7 | Capital International Investors | 5.15M | n/a | $896.60M | 0.1% | n/c | 1 | SEC ↗ |
| 8 | Artisan Partners Limited Partnership | 4.84M | n/a | $843.01M | 1.3% | n/c | 1 | SEC ↗ |
| 9 | D. E. Shaw & Co. ✦ | 4.35M | -23.1% | $757.25M | 0.6% | ▼ Trim | 7 | SEC ↗ ×2 |
| 10 | Geode Capital Management ✦ (passive) | 4.30M | +14.3% | $751.94M | 0.0% | ▲ Add | 7 | SEC ↗ ×2 |
| 11 | T. Rowe Price ✦ | 4.04M | -41.7% | $703.03M | 0.1% | ▼ Trim | 7 | SEC ↗ ×2 |
| 12 | Norges Bank ✦ (passive) | 2.91M | New | $506.63M | 0.1% | New | 1 | SEC ↗ |
| 13 | Franklin Resources Inc | 2.76M | n/a | $479.57M | 0.1% | n/c | 1 | SEC ↗ ×8 |
| 14 | Ameriprise Financial Inc | 1.97M | n/a | $342.66M | 0.1% | n/c | 1 | SEC ↗ ×7 |
| 15 | UBS Group AG | 1.87M | n/a | $325.04M | 0.1% | n/c | 1 | SEC ↗ ×5 |
| 16 | Bank Of America Corp /De/ | 1.73M | n/a | $300.34M | 0.0% | n/c | 1 | SEC ↗ ×8 |
| 17 | Morgan Stanley ✦ | 1.63M | +69.3% | $284.02M | 0.0% | ▲ Add | 2 | SEC ↗ ×15 |
| 18 | Duquesne Family Office ✦ | 1.48M | -38.9% | $257.88M | 6.1% | ▼ Trim | 7 | SEC ↗ |
| 19 | Bank of New York Mellon Corp | 1.39M | n/a | $241.92M | 0.0% | n/c | 1 | SEC ↗ ×17 |
| 20 | Millennium Management ✦ | 1.31M | -43.9% | $228.28M | 0.2% | ▼ Trim | 7 | SEC ↗ |
| 21 | Goldman Sachs Group ✦ | 1.24M | +50.1% | $216.66M | 0.0% | ▲ Add | 2 | SEC ↗ ×5 |
| 22 | Northern Trust Corp | 1.24M | n/a | $215.54M | 0.0% | n/c | 1 | SEC ↗ ×7 |
| 23 | Nomura Asset Management… | 1.18M | n/a | $205.89M | 0.3% | n/c | 1 | SEC ↗ |
| 24 | Citadel Advisors ✦ | 1.16M | -43.8% | $201.42M | 0.1% | ▼ Trim | 7 | SEC ↗ ×2 |
| 25 | Charles Schwab Investment… | 1.03M | n/a | $178.80M | 0.0% | n/c | 1 | SEC ↗ |
| 26 | Two Sigma Investments ✦ | 962.16K | +24.5% | $167.45M | 0.3% | ▲ Add | 7 | SEC ↗ |
| 27 | Pictet Asset Management Holding SA | 958.96K | n/a | $167.26M | 0.2% | n/c | 1 | SEC ↗ |
| 28 | UBS AM, a distinct business unit of… | 943.31K | n/a | $164.17M | 0.0% | n/c | 1 | SEC ↗ ×10 |
| 29 | Amundi | 917.00K | n/a | $159.59M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 30 | Bnp Paribas Financial Markets | 915.42K | n/a | $159.32M | 0.1% | n/c | 1 | SEC ↗ |
| 31 | Sei Investments Co | 890.17K | n/a | $154.92M | 0.2% | n/c | 1 | SEC ↗ ×3 |
| 32 | FIL Ltd | 838.51K | n/a | $145.93M | 0.1% | n/c | 1 | SEC ↗ |
| 33 | Clearbridge Investments, LLC | 819.01K | n/a | $142.54M | 0.1% | n/c | 1 | SEC ↗ |
| 34 | Holocene Advisors, LP | 801.16K | n/a | $139.43M | 0.3% | n/c | 1 | SEC ↗ |
| 35 | Janus Henderson Group Plc | 800.55K | n/a | $139.33M | 0.1% | n/c | 1 | SEC ↗ ×4 |
| 36 | Raymond James Financial Inc | 779.25K | n/a | $135.65M | 0.0% | n/c | 1 | SEC ↗ ×6 |
| 37 | Principal Financial Group Inc | 771.36K | n/a | $134.25M | 0.1% | n/c | 1 | SEC ↗ ×2 |
| 38 | Nuveen, LLC | 650.40K | n/a | $113.20M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 39 | Victory Capital Management Inc | 646.71K | n/a | $112.55M | 0.1% | n/c | 1 | SEC ↗ |
| 40 | Alliancebernstein L.P. | 642.72K | n/a | $111.86M | 0.0% | n/c | 1 | SEC ↗ |
| 41 | Federated Hermes, Inc. | 632.30K | n/a | $110.05M | 0.2% | n/c | 1 | SEC ↗ ×2 |
| 42 | Deutsche Bank Ag\ | 590.03K | n/a | $102.69M | 0.0% | n/c | 1 | SEC ↗ ×7 |
| 43 | Wells Fargo & Company/Mn | 586.65K | n/a | $102.10M | 0.0% | n/c | 1 | SEC ↗ ×5 |
| 44 | Swiss National Bank | 579.11K | n/a | $100.79M | 0.1% | n/c | 1 | SEC ↗ |
| 45 | Jennison Associates Llc | 562.30K | n/a | $97.86M | 0.1% | n/c | 1 | SEC ↗ |
| 46 | Legal & General Group Plc | 540.31K | n/a | $94.04M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 47 | Royal Bank Of Canada | 506.81K | n/a | $88.20M | 0.0% | n/c | 1 | SEC ↗ ×8 |
| 48 | Wellington Management ✦ | 486.14K | -32.3% | $84.61M | 0.0% | ▼ Trim | 7 | SEC ↗ ×5 |
| 49 | AQR Capital Management ✦ | 468.26K | +63.0% | $81.50M | 0.0% | ▲ Add | 7 | SEC ↗ ×6 |
| 50 | Barclays Plc | 444.71K | n/a | $77.40M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 51 | Sumitomo Mitsui Trust Group, Inc. | 435.44K | n/a | $75.78M | 0.0% | n/c | 1 | SEC ↗ |
| 52 | Dimensional Fund Advisors Lp | 399.07K | n/a | $69.46M | 0.0% | n/c | 1 | SEC ↗ ×5 |
| 53 | Marshall Wace ✦ | 389.88K | -40.8% | $67.85M | 0.1% | ▼ Trim | 7 | SEC ↗ ×2 |
| 54 | Ensign Peak Advisors, Inc | 382.20K | n/a | $66.52M | 0.1% | n/c | 1 | SEC ↗ |
| 55 | Balyasny Asset Management L.P. | 380.56K | n/a | $66.23M | 0.1% | n/c | 1 | SEC ↗ |
| 56 | California Public Employees… | 354.91K | n/a | $61.77M | 0.0% | n/c | 1 | SEC ↗ |
| 57 | ProShare Advisors LLC | 340.74K | n/a | $59.30M | 0.1% | n/c | 1 | SEC ↗ |
| 58 | BNP Paribas Asset Management… | 328.33K | n/a | $57.16M | 0.1% | n/c | 1 | SEC ↗ ×3 |
| 59 | California State Teachers… | 310.33K | n/a | $54.01M | 0.1% | n/c | 1 | SEC ↗ |
| 60 | Adage Capital Partners ✦ | 300.00K | -76.0% | $52.21M | 0.1% | ▼ Trim | 7 | SEC ↗ |
| 61 | National Pension Service | 280.44K | n/a | $48.81M | 0.0% | n/c | 1 | SEC ↗ |
| 62 | New York State Common Retirement… | 276.28K | n/a | $48.08M | 0.1% | n/c | 1 | SEC ↗ |
| 63 | Envestnet Asset Management Inc | 276.11K | n/a | $48.05M | 0.0% | n/c | 1 | SEC ↗ |
| 64 | Rhumbline Advisers | 268.33K | n/a | $46.70M | 0.0% | n/c | 1 | SEC ↗ |
| 65 | Td Asset Management Inc | 262.48K | n/a | $45.68M | 0.0% | n/c | 1 | SEC ↗ |
| 66 | Aberdeen Group plc | 253.11K | n/a | $44.05M | 0.1% | n/c | 1 | SEC ↗ ×3 |
| 67 | First Trust Advisors Lp | 247.94K | n/a | $43.15M | 0.0% | n/c | 1 | SEC ↗ |
| 68 | Hsbc Holdings Plc | 246.53K | n/a | $42.99M | 0.0% | n/c | 1 | SEC ↗ ×16 |
| 69 | Citigroup Inc | 237.91K | n/a | $41.41M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 70 | Mitsubishi UFJ Asset Management… | 222.27K | n/a | $39.37M | 0.0% | n/c | 1 | SEC ↗ |
| 71 | Allspring Global Investments… | 220.08K | n/a | $38.98M | 0.1% | n/c | 1 | SEC ↗ ×3 |
| 72 | Neuberger Berman Group LLC | 207.87K | n/a | $36.18M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 73 | Voya Investment Management Llc | 200.96K | n/a | $34.98M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 74 | Loomis Sayles & Co L P | 199.96K | n/a | $34.80M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 75 | Susquehanna International Group, Llp | 188.58K | n/a | $32.82M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 76 | American Century Companies Inc | 185.09K | n/a | $32.21M | 0.0% | n/c | 1 | SEC ↗ |
| 77 | State Board Of Administration Of… | 180.29K | n/a | $31.38M | 0.1% | n/c | 1 | SEC ↗ |
| 78 | Zurcher Kantonalbank (Zurich… | 161.82K | n/a | $28.16M | 0.1% | n/c | 1 | SEC ↗ |
| 79 | Russell Investments Group, Ltd. | 145.09K | n/a | $25.25M | 0.0% | n/c | 1 | SEC ↗ ×12 |
| 80 | LPL Financial LLC | 132.78K | n/a | $23.11M | 0.0% | n/c | 1 | SEC ↗ |
| 81 | State Of Wisconsin Investment Board | 131.62K | n/a | $22.91M | 0.1% | n/c | 1 | SEC ↗ |
| 82 | MIRAE ASSET GLOBAL ETFS HOLDINGS… | 120.38K | n/a | $20.95M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 83 | Manufacturers Life Insurance… | 118.85K | n/a | $20.69M | 0.0% | n/c | 1 | SEC ↗ |
| 84 | Man Group plc | 118.36K | n/a | $20.60M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 85 | Danske Bank A/S | 110.26K | n/a | $19.19M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 86 | Aviva Plc | 109.40K | n/a | $19.04M | 0.0% | n/c | 1 | SEC ↗ |
| 87 | National Bank Of Canada /Fi/ | 108.71K | n/a | $18.92M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 88 | LMR Partners LLP | 107.51K | n/a | $18.71M | 0.2% | n/c | 1 | SEC ↗ |
| 89 | Assenagon Asset Management S.A. | 106.83K | n/a | $18.59M | 0.0% | n/c | 1 | SEC ↗ |
| 90 | Universal- Beteiligungs- und… | 103.31K | n/a | $17.98M | 0.0% | n/c | 1 | SEC ↗ |
| 91 | Nomura Asset Management Co Ltd | 83.54K | n/a | $14.54M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 92 | Mitsubishi UFJ Trust & Banking Corp | 83.03K | n/a | $14.45M | 0.0% | n/c | 1 | SEC ↗ |
| 93 | Asset Management One Co., Ltd. | 80.89K | n/a | $14.26M | 0.0% | n/c | 1 | SEC ↗ |
| 94 | Mirae Asset Global Investments Co.… | 78.49K | n/a | $13.66M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 95 | Korea Investment CORP | 72.63K | n/a | $12.64M | 0.0% | n/c | 1 | SEC ↗ |
| 96 | Creative Planning | 70.50K | n/a | $12.27M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 97 | Stifel Financial Corp | 69.24K | n/a | $12.05M | 0.0% | n/c | 1 | SEC ↗ ×5 |
| 98 | Squarepoint Ops LLC | 66.40K | n/a | $11.56M | 0.0% | n/c | 1 | SEC ↗ |
| 99 | Healthcare Of Ontario Pension Plan… | 65.31K | n/a | $11.37M | 0.0% | n/c | 1 | SEC ↗ |
| 100 | Bank Of Montreal /Can/ | 62.80K | n/a | $10.93M | 0.0% | n/c | 1 | SEC ↗ ×5 |
“Their weight” = the position's share of that manager's reported 13F equity value: the conviction measure. ✦ = curated manager.
New buyers
| Norges Bank | $506.63M | 0.1% |
Exited
| Point72 Asset Management | $66.85M | was 0.2% |
Full-market context: across ALL 13F filers (SEC structured data, Q1 2026): 664 holders, 192.22M shares, $30.07B reported. This is a different, older period than the tracked-universe figures above and the two are never mixed.
Frequently co-owned
What else this security's tracked holders most often hold: shared-ownership counts, not fundamental relationships.
Open-market purchases (P)
No open-market insider purchases in our coverage window.
Open-market sales (S)
Sep 09
Brennan David R
Director · 25.00K sh · $3.10M
Aug 17
SHAROKY MELVIN MD
Director · 5.00K sh · $637,650
Aug 10
Adsett Roger
Officer · 239.85K sh · $31.96M
Awards, exercises and tax withholding are never counted as buys or sales here. Methodology
Aug 14
SC 13G/A: Darwin Global Management, Ltd.
Aug 06
SC 13G/A: FMR LLC
Jul 22
SC 13G/A: JPMORGAN CHASE & CO
Provenance: Ownership from parsed 13F common-stock positions (tracked universe, comparable sets for changes); insider rows from Forms 3/4/5; stakes from Schedules 13D/13G; every filing links to its original on SEC EDGAR.
Reporting period: Q4 2025 ·
Methodology ·
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